Levetiracetam combined with Midazolam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Fibrillation Other Serious 7/14/2010 26 Female 176 lb 7/26/2010 Physician Portugal
Primary
Concomitant
Weight Increased Hospitalization 16 Male 9/29/2010 Physician United States
Primary
Secondary
Concomitant
Facial Bones Fracture Hospitalization 19 Female 2/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 16 Male 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 19 Female 3/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 12/1/2010 74 Male 143 lb 3/29/2011 Physician Spain
Primary
Concomitant
International Normalised Ratio Increased Other Serious 71 Female 5/11/2011 Other Health Professional United States
Primary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 71 Female 11/23/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 71 Female 11/23/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Complex Partial Seizures Other Serious 11/27/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Pseudomonal Bacteraemia Hospitalization 6/22/2011 46 Female 117 lb 11/28/2011 Consumer Germany
Primary
Concomitant
Epilepsy Other Serious 71 Female 12/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Lactic Acid Increased Hospitalization 12/8/2011 United States
Primary
Concomitant
Interacting
Gaze Palsy Other Serious 25 Female 12/16/2011 Physician United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 32 Male 134 lb 12/22/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 32 Male 134 lb 12/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hellp Syndrome Other Serious 41 Female 161 lb 12/20/2011 Other Health Professional India
Primary
Secondary
Tubulointerstitial Nephritis Hospitalization 32 Male 134 lb 12/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 1/1/2011 32 Male 134 lb 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 32 Male 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 32 Male 61 lb 12/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis Hospitalization 32 Male 12/30/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Propofol Infusion Syndrome Death 14 Female 2/10/2012 Physician Korea, Republic Of
Primary
Concomitant
Activated Partial Thromboplastin Time Prolonged Required Intervention 71 Female 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Gaze Palsy Other Serious 4/1/2011 25 Female 2/16/2012 Physician United Kingdom
Primary
Concomitant
Toxicity To Various Agents Hospitalization 8 Male 3/9/2012 Other Health Professional France
Primary
Secondary
Drug Interaction Other Serious 32 Female 3/19/2012 Other Health Professional Colombia
Primary
Concomitant
Interacting
Alanine Aminotransferase Increased Other Serious 42 Male 3/20/2012 Other Health Professional Colombia
Primary
Concomitant
Interacting
Gaze Palsy Other Serious 4/1/2011 25 Female 3/28/2012 Physician United Kingdom
Primary
Concomitant
Status Epilepticus Hospitalization 12 Male 4/18/2012 Physician Turkey
Primary
Secondary
Concomitant
Chorea Hospitalization 16 Female 110 lb 5/16/2012 Other Health Professional Australia
Primary
Concomitant
Affective Disorder Other Serious 16 Male 5/30/2012 Physician United States
Primary
Secondary
Interacting
Jaundice Hospitalization 5/12/2012 47 Male 172 lb 6/6/2012 Physician Netherlands
Primary
Secondary
Concomitant
Death Death 27 Female 6/12/2012 Other Health Professional Canada
Primary
Secondary
Death Death 27 Female 6/12/2012 Other Health Professional Canada
Primary
Secondary
Sepsis Other Serious 37 Female 6/26/2012 Other Health Professional Argentina
Primary
Concomitant
Interacting
Sepsis Other Serious 56 Female 6/26/2012 Other Health Professional Argentina
Primary
Concomitant
Interacting
Hepatic Function Abnormal Hospitalization 5/4/2012 47 Male 172 lb 6/27/2012 Physician Netherlands
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/1/2011 32 Male 134 lb 6/29/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 56 Female 6/29/2012 Other Health Professional Brazil
Primary
Concomitant
Interacting
Death Death 27 Female 7/2/2012 Other Health Professional Canada
Primary
Secondary
Inhibitory Drug Interaction Death 37 Female 7/2/2012 Other Health Professional Argentina
Primary
Concomitant
Interacting
Death Death 27 Female 7/2/2012 Other Health Professional Canada
Primary
Secondary
Tubulointerstitial Nephritis Hospitalization 11/1/2011 32 Male 7/5/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Protrusion Tongue Other Serious 31 Female 7/9/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 11/1/2011 32 Male 7/10/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 31 Female 7/13/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 32 Male 61 lb 7/5/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Movement Disorder Other Serious 31 Female 7/10/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 31 Female 7/10/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 60 Male 8/14/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 30 Female 8/15/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 6/2/2012 78 Male 219 lb 8/27/2012 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 16 Male 3/8/2013 Physician Us
Primary
Secondary
Interacting
Weight Increased Hospitalization 16 Male 3/18/2013 Other Health Professional Country Not Specified
Primary
Secondary
Jaundice Hospitalization 22 Female 2/8/2013 Pharmacist Cn
Primary
Secondary
Concomitant
Hyperammonaemic Encephalopathy Other Serious 32 Female 11/13/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Interacting
Hyperammonaemic Encephalopathy Other Serious 42 Male 11/13/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Interacting
Status Epilepticus Death 27 Female 10/25/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Hypotension Other Serious 60 Male 9/14/2012 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 69 Male 9/15/2012 Physician Country Not Specified
Primary
Secondary
Drug Ineffective Hospitalization 60 Male 9/15/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 19 Male 9/15/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 69 Female 11/14/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 41 Female 9/15/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 55 Female 9/15/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 76 Male 9/15/2012 Physician Country Not Specified
Primary
Secondary
Drug Ineffective Hospitalization 35 Female 9/15/2012 Physician Country Not Specified
Primary
Secondary
Drug Ineffective Hospitalization 62 Male 11/13/2012 Physician Country Not Specified
Primary
Secondary
Drug Ineffective Hospitalization 48 Female 9/15/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 52 Male 9/15/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 74 Male 9/15/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 61 Male 9/15/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 64 Male 9/15/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 84 Male 9/15/2012 Physician Country Not Specified
Primary
Secondary
Drug Ineffective Hospitalization 65 Female 9/15/2012 Physician Country Not Specified
Primary
Secondary
Drug Ineffective Hospitalization 59 Male 11/13/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 23 Female 11/15/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Death Death 63 Female 9/17/2012 Physician Ch
Primary
Secondary
Death Death 64 Male 9/17/2012 Physician Ch
Primary
Secondary
No Therapeutic Response Death 23 Female 9/10/2012 Us
Primary
Secondary
Concomitant
Death Death 69 Male 9/21/2012 Physician Ch
Primary
Secondary
Death Death 76 Male 9/21/2012 Physician Ch
Primary
Secondary
Death Death 32 Male 9/21/2012 Physician Ch
Primary
Secondary
Death Death 84 Male 9/21/2012 Physician Ch
Primary
Secondary
Death Death 60 Male 9/21/2012 Physician Ch
Primary
Secondary
Death Death 39 Male 9/21/2012 Physician Ch
Primary
Secondary
Treatment Failure Hospitalization 23 Female 9/14/2012 Cl
Primary
Secondary
Concomitant
Hyperammonaemic Encephalopathy Hospitalization 42 Male 9/29/2012 Other Health Professional Co
Primary
Concomitant
Interacting
Potentiating Drug Interaction Hospitalization 32 Female 9/29/2012 Other Health Professional Co
Primary
Concomitant
Interacting
Pneumonia Other Serious 55 Female 10/25/2012 Other Health Professional Us
Primary
Concomitant
Drug Ineffective For Unapproved Indication Hospitalization 5 Female 11/30/2012 Physician Es
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/22/2010 44 Female 9/16/2013 Lawyer Us
Primary
Concomitant
Hyperammonaemic Encephalopathy Other Serious 32 Female 12/5/2012 Other Health Professional Co
Primary
Concomitant
Interacting
Hyperammonaemic Encephalopathy Other Serious 42 Male 12/5/2012 Other Health Professional Co
Primary
Concomitant
Interacting
Status Epilepticus Hospitalization 47 Male 4/22/2013 Physician At
Primary
Concomitant
Physical Disability Other Serious 36 Female 1/4/2013 Physician Ch
Primary
Secondary
Concomitant
Tachycardia Other Serious 1 Female 1/14/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Shock Death 27 Female 1/29/2013 Physician Ca
Primary
Secondary
Shock Death 27 Female 1/29/2013 Physician Ca
Primary
Secondary
Electroencephalogram Abnormal Other Serious 57 Female 2/7/2013 Other Health Professional De
Primary
Secondary
Respiratory Acidosis Other Serious 11/28/2012 1 Female 19 lb 2/14/2013 Physician Gb
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Hospitalization 1/2013 72 Male 4/4/2013 Physician De
Primary
Secondary
Concomitant
Respiratory Acidosis Death 11/28/2012 1 Female 19 lb 10/8/2013 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 11/28/2012 1 Female 2/20/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Electroencephalogram Abnormal Other Serious 57 Female 2/22/2013 Physician De
Primary
Secondary
Tachycardia Other Serious 0 Male 2/28/2013 Us
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 76 Male 3/7/2013 Physician Gb
Primary
Concomitant
Viral Infection Death 1/3/2013 8 Male 2/12/2013 Other Health Professional Nl
Primary
Secondary
Respiratory Acidosis Death 11/28/2012 1 Female 19 lb 2/22/2013 Consumer Gb
Primary
Secondary
Concomitant
Respiratory Acidosis Death 11/28/2012 1 Female 19 lb 2/21/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 76 Male 3/18/2013 Physician Gb
Primary
Concomitant
Grand Mal Convulsion Life Threatening 11/2012 11 Male 72 lb 3/13/2013 Consumer Gb
Primary
Concomitant
Status Epilepticus Other Serious 78 Male 3/22/2013 Physician Gb
Primary
Concomitant
Myocarditis Other Serious 14 Male 4/15/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
No Therapeutic Response Death 0 Male 7 lb 4/30/2013 Other Health Professional Au
Primary
Secondary
Drug Ineffective For Unapproved Indication Death 74 Female 4/29/2013 Physician Be
Primary
Secondary
Concomitant
Drug Ineffective For Unapproved Indication Death 32 Male 4/29/2013 Physician Be
Primary
Secondary
Concomitant
Death Death 1 Male 5/21/2013 Physician Be
Primary
Concomitant
Death Neonatal Death Female 6/5/2013 Physician Au
Primary
Concomitant
Drug Ineffective For Unapproved Indication Other Serious 21 Male 6/27/2013 Physician Us
Primary
Concomitant
Shock Death 27 Female 6/28/2013 Physician Ca
Primary
Secondary
Off Label Use Other Serious 22 Male 7/8/2013 Other Health Professional Us
Primary
Concomitant
Cytomegalovirus Infection Other Serious 4/24/2013 55 Male 238 lb 8/27/2013 Physician Us
Primary
Secondary
Concomitant
Hypotension Hospitalization 60 Male 7/29/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Sepsis Other Serious 39 Male 8/1/2013 Physician Th
Primary
Concomitant
Sepsis Death 83 Male 8/2/2013 Physician Th
Primary
Concomitant
Sepsis Other Serious 69 Female 8/2/2013 Physician Th
Primary
Concomitant
Sepsis Other Serious 49 Male 8/2/2013 Physician Th
Primary
Concomitant
Sepsis Other Serious 49 Male 8/2/2013 Physician Th
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious Female 8/2/2013 Physician Ro
Primary
Concomitant
Withdrawal Syndrome Other Serious 26 Female 8/2/2013 Other Health Professional Ro
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 7/24/2013 54 Female 234 lb 11/13/2013 Pharmacist Us
Primary
Concomitant
Rash Other Serious 6/9/2013 46 Male 187 lb 11/6/2013 Other Health Professional De
Primary
Secondary
Concomitant
No Adverse Event 4/10/2013 55 Male 238 lb 11/1/2013 Physician Us
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 76 Male 4/9/2013 Gb
Primary
Concomitant
Status Epilepticus Death 11/2008 35 Female 11/1/2013 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Death 1 Male 9/25/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 1 Male 10/3/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Status Epilepticus Life Threatening 1 Male 10/1/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 0 Female 10/1/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 10 Male 10/8/2013 Physician Us
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 10 Female 10/8/2013 Physician Us
Primary
Secondary
Concomitant
Septic Shock Other Serious 0 Female 10/8/2013 Physician Us
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 30 Male 10/9/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Vision Blurred Other Serious Male 10/10/2013 Other Health Professional Au
Primary
Secondary
Concomitant
Drug Ineffective Death 27 Female 10/7/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 46 Female 10/15/2013 Other Health Professional Tr
Primary
Secondary
Toxicity To Various Agents Other Serious 46 Female 10/15/2013 Other Health Professional Tr
Primary
Secondary
Toxicity To Various Agents Hospitalization 46 Female 10/15/2013 Other Health Professional Tr
Primary
Secondary

Drug Data