Levemir combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Injection Site Swelling Other Serious 6/30/2005 58 Female 150 lb 1/5/2006 Physician Turkey
Primary
Concomitant
Fall Hospitalization 2/3/2006 73 Female 2/28/2006 Consumer Brazil
Primary
Secondary
Concomitant
Injection Site Ulcer Other Serious 2/13/2006 51 Male 249 lb 3/2/2006 Other Health Professional Canada
Primary
Concomitant
Head Injury Hospitalization 2/3/2006 73 Female 123 lb 3/23/2006 Consumer Brazil
Primary
Secondary
Concomitant
Head Injury Hospitalization 2/3/2006 73 Female 123 lb 4/14/2006 Consumer Brazil
Primary
Secondary
Concomitant
Cellulitis Hospitalization 12/27/2005 61 Male 359 lb 6/15/2006 Physician Canada
Primary
Concomitant
Road Traffic Accident Hospitalization 9/18/2005 56 Male 245 lb 6/15/2006 Physician United Kingdom
Primary
Concomitant
Tendonitis 12/1/2005 70 Female 198 lb 4/17/2006 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 4/25/2005 61 Female 132 lb 7/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 11/28/2006 62 Female 180 lb 12/11/2006 Consumer United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 11/30/2006 79 Male 12/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 11/30/2006 79 Male 1/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 4/4/2007 49 Male 4/9/2007 Consumer United States
Primary
Concomitant
Hyperhidrosis Other Serious Female 9/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sinusitis 12/23/2006 68 Male 208 lb 8/16/2007 Physician United States
Primary
Concomitant
Injection Site Rash Other Serious Male 220 lb 10/17/2007 Lawyer United Arab Emirates
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 64 Male 12/31/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Injection Site Pain 1/1/2006 Male 220 lb 3/15/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 9/1/2007 53 Female 3/17/2008 Consumer United States
Primary
Concomitant
Weight Increased 4/1/2007 24 Female 3/14/2008 Consumer United States
Primary
Concomitant
Autoimmune Hepatitis Hospitalization 5/1/2008 60 Female 7/14/2008 Physician Japan
Primary
Secondary
Concomitant
Stomach Discomfort Other Serious 7/1/2008 Female 301 lb 9/4/2008 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 8/1/2008 45 Male 10/8/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 9/26/2008 58 Female 207 lb 10/16/2008 Consumer Brazil
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/26/2008 58 Female 207 lb 10/28/2008 Physician Brazil
Primary
Secondary
Concomitant
Oedema Mouth 11/4/2008 51 Male 350 lb 12/2/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2007 55 Female 180 lb 1/23/2009 Consumer United States
Primary
Concomitant
Metabolic Syndrome Hospitalization 12/19/2008 22 Male 287 lb 2/3/2009 Physician Finland
Primary
Concomitant
Gangrene Other Serious 9/1/2008 48 Male 187 lb 2/26/2009 Pharmacist Israel
Primary
Concomitant
Hysterectomy Other Serious 2/9/2009 37 Female 2/26/2009 Consumer Israel
Primary
Concomitant
Insulin Resistance Other Serious 68 Female 2/27/2009 Physician United Kingdom
Primary
Concomitant
Retinopathy Other Serious 68 Female 3/23/2009 Physician United Kingdom
Primary
Concomitant
Death Death 3/2/2009 Male 3/25/2009 Physician United States
Primary
Concomitant
Pyrexia Other Serious 12/18/2008 58 Female 134 lb 3/27/2009 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Pancreatitis Hospitalization 8/1/2007 Male 275 lb 3/25/2009 Physician United States
Primary
Concomitant
Hysterectomy Other Serious 2/9/2009 37 Female 4/1/2009 Consumer Israel
Primary
Concomitant
Road Traffic Accident Other Serious 10/15/2008 66 Male 201 lb 6/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Post Procedural Haematoma Hospitalization 47 176 lb 6/10/2009 Physician United Kingdom
Primary
Concomitant
Blood Glucose Increased 65 Female 7/21/2008 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 8/1/2007 76 Female 4/25/2008 Consumer United States
Primary
Concomitant
Nausea 2/18/2008 66 Male 4/25/2008 Consumer United States
Primary
Concomitant
Weight Increased 62 Female 4/25/2008 Consumer United States
Primary
Secondary
Concomitant
Injection Site Haematoma 53 Female 1/23/2008 Consumer United States
Primary
Concomitant
Palpitations 3/1/2008 65 Male 7/21/2008 Consumer United States
Primary
Concomitant
Palpitations 4/1/2008 60 Female 7/21/2008 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/23/2008 68 Female 179 lb 7/24/2009 Physician Germany
Primary
Concomitant
Rectal Haemorrhage 1/1/2009 Female 288 lb 7/29/2009 Consumer United States
Primary
Concomitant
Fall Hospitalization 3/3/2007 Male 164 lb 8/3/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Death 3/2/2009 Male 8/6/2009 Physician United States
Primary
Concomitant
Renal Disorder Death 67 Male 8/3/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2009 59 Male 231 lb 8/12/2009 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Stromal Tumour Life Threatening Male 8/17/2009 Physician Australia
Primary
Concomitant
Renal Failure Acute Death 3/2/2009 Male 8/20/2009 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/14/2009 United States
Primary
Concomitant
Wound Dehiscence Hospitalization 4/2/2009 68 Female 179 lb 9/18/2009 Physician Germany
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 10/22/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 5/1/2009 Female 315 lb 11/5/2009 Physician United States
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 8/27/2009 Female 220 lb 11/25/2009 Consumer United States
Primary
Concomitant
Swelling Face Life Threatening 11/19/2009 Male 266 lb 12/16/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/23/2009 1/4/2010 Physician Netherlands
Primary
Secondary
Concomitant
Urine Output Increased Other Serious 12/1/2009 53 Female 157 lb 1/14/2010 Physician Korea, Republic Of
Primary
Concomitant
Vomiting Hospitalization 1/1/2009 53 Female 157 lb 1/18/2010 Physician Korea, Republic Of
Primary
Concomitant
Urine Output Decreased Other Serious 4/19/2008 Female 200 lb 1/18/2010 Physician United States
Primary
Secondary
Concomitant
Swelling Face Life Threatening 11/19/2009 Male 266 lb 1/20/2010 Physician United States
Primary
Secondary
Concomitant
Swelling Face Life Threatening 11/19/2009 Male 266 lb 2/3/2010 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 2/1/2010 Male 155 lb 3/19/2010 Consumer United States
Primary
Secondary
Concomitant
Pruritus 60 Male 4/7/2010 Consumer
Primary
Concomitant
Somnolence 2/17/2010 60 Male 4/7/2010 Consumer
Primary
Concomitant
Sternal Fracture Hospitalization 1/1/2009 54 Male 287 lb 4/14/2010 Physician Germany
Primary
Concomitant
Loss Of Consciousness Hospitalization 2/1/2010 69 Male 154 lb 4/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/26/2010 60 Male 355 lb 5/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 4/7/2009 35 Female 112 lb 6/4/2010 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/17/2010 62 Female 6/4/2010 Physician France
Primary
Secondary
Concomitant
Vision Blurred Other Serious 9/1/2008 65 Female 229 lb 6/7/2010 Physician Canada
Primary
Concomitant
Increased Appetite Other Serious 31 Female 146 lb 6/7/2010 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Other Serious 3/2/2010 55 Male 222 lb 6/10/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/20/2003 61 Female 203 lb 6/11/2010 Other Health Professional United States
Primary
Concomitant
Testicular Swelling Hospitalization 3/1/2010 73 Male 236 lb 6/17/2010 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 54 Female 205 lb 6/18/2010 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Other Serious Female 172 lb 7/19/2010 Physician United States
Primary
Concomitant
Night Sweats Other Serious 7/1/2010 42 Male 301 lb 8/2/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Vessel Disorder Other Serious 4/7/2010 63 Male 8/2/2010 Physician United States
Primary
Concomitant
Tibia Fracture Other Serious 7/31/2010 51 Male 207 lb 8/16/2010 Consumer Brazil
Primary
Concomitant
Skin Burning Sensation 10/1/2009 46 Male 8/16/2010 Consumer United States
Primary
Concomitant
Injection Site Pain Other Serious 7/24/2010 68 Male 204 lb 8/17/2010 Physician Pakistan
Primary
Concomitant
Weight Decreased Other Serious Female 219 lb 8/13/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/11/2010 72 Female 8/20/2010 Consumer United States
Primary
Concomitant
Sepsis Hospitalization Male 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 6/1/2010 69 Male 295 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Flushing 8/1/2009 75 Male 177 lb 8/27/2010 United States
Primary
Concomitant
Nausea Female 225 lb 8/28/2010 United States
Primary
Concomitant
Pruritus Male 280 lb 8/28/2010 Consumer United States
Primary
Concomitant
Vision Blurred 3/1/2010 58 8/29/2010 Consumer United States
Primary
Concomitant
Flushing 5/27/2010 65 Female 245 lb 8/29/2010 Consumer United States
Primary
Concomitant
Pruritus 6/1/2010 48 Female 211 lb 8/29/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 8/1/2010 51 Female 9/1/2010 Consumer United States
Primary
Concomitant
Injection Site Pain Other Serious 7/26/2010 68 Male 204 lb 9/7/2010 Physician Pakistan
Primary
Concomitant
Rash Generalised Other Serious 8/1/2009 57 Female 180 lb 9/10/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 7/15/2010 59 Male 202 lb 8/30/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2010 67 Female 9/24/2010 Consumer France
Primary
Secondary
Concomitant
Vomiting Other Serious 6/30/2010 67 Female 9/27/2010 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 6/1/2010 69 Male 295 lb 9/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 7/1/2010 66 Female 10/6/2010 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Hospitalization 71 Female 10/7/2010 Pharmacist Canada
Primary
Concomitant
Pneumonia Hospitalization 1/1/2009 72 Female 170 lb 10/4/2010 Consumer United States
Primary
Concomitant
Myalgia Other Serious 7/15/2010 Female 10/8/2010 Physician South Africa
Primary
Concomitant
Pancreatitis Acute Other Serious Female 171 lb 10/11/2010 Consumer United States
Primary
Concomitant
Off Label Use Hospitalization Female 175 lb 10/11/2010 Consumer United States
Primary
Concomitant
Blood Potassium Increased Other Serious 9/20/2010 68 Male 150 lb 10/13/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 9/2/2010 48 Male 250 lb 9/30/2010 Physician United States
Primary
Concomitant
Tuberculosis Hospitalization 6/1/2010 52 Male 10/18/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 1/1/2010 66 Male 188 lb 10/22/2010 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Death 1/22/2010 58 Female 245 lb 10/28/2010 Physician Greece
Primary
Secondary
Concomitant
Headache 45 Female 10/13/2010 Consumer United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 5/11/2010 59 Female 301 lb 11/2/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 8/1/2010 51 Female 11/3/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 64 Female 11/12/2010 Consumer United States
Primary
Secondary
Tendonitis Other Serious Female 11/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Metastatic Life Threatening 10/1/2010 63 Female 209 lb 11/17/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Tremor Other Serious 6/10/2010 49 Female 324 lb 10/28/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 48 Male 11/24/2010 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 38 Female 239 lb 11/29/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 63 Male 271 lb 11/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 65 Female 287 lb 11/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 63 Male 11/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 63 Male 11/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 63 Male 271 lb 12/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 8/18/2010 56 Female 168 lb 12/2/2010 Other Health Professional Canada
Primary
Concomitant
Visual Acuity Reduced Other Serious Female 200 lb 12/1/2010 Consumer United States
Primary
Concomitant
Blood Potassium Increased Other Serious 9/20/2010 68 Male 150 lb 12/7/2010 Consumer United States
Primary
Concomitant
Panniculitis Hospitalization Male 524 lb 12/13/2010 Physician United States
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization Female 12/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatic Carcinoma Metastatic Life Threatening 10/1/2010 63 Female 209 lb 12/17/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Blood Potassium Increased Other Serious 9/20/2010 68 Male 150 lb 12/29/2010 Consumer United States
Primary
Concomitant
Overdose 68 Female 1/7/2011 Consumer United States
Primary
Concomitant
Application Site Pruritus Other Serious 12/1/2010 86 Male 168 lb 1/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cataract Other Serious 4/1/2010 58 Female 222 lb 1/12/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 4/1/2010 54 Male 270 lb 1/27/2011 Consumer United States
Primary
Concomitant
Depression 10/1/2010 74 Female 185 lb 1/30/2011 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious Female 2/2/2011 Consumer United States
Primary
Secondary
Concomitant
Acute Abdomen Hospitalization 12/12/2010 66 Female 216 lb 2/2/2011 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 1/21/2011 79 Female 2/3/2011 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 1/1/2007 41 Female 273 lb 2/10/2011 United States
Primary
Secondary
Concomitant
Abortion Spontaneous Hospitalization 4/12/2010 26 Female 236 lb 2/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Injection Site Erythema Other Serious 1/12/2010 84 Female 2/21/2011 Consumer United States
Primary
Concomitant
Colitis Hospitalization 12/12/2010 66 Female 216 lb 2/22/2011 Consumer United Kingdom
Primary
Concomitant
Drug Dose Omission Other Serious 1/17/2011 57 Female 2/28/2011 Consumer United States
Primary
Concomitant
Skin Depigmentation 1/1/2010 82 Male 3/11/2011 Consumer United States
Primary
Concomitant
Haemoptysis Other Serious 12/12/2010 66 Female 216 lb 3/14/2011 Consumer Germany
Primary
Concomitant
Pneumonia Hospitalization 1/21/2011 79 Female 3/14/2011 Physician United States
Primary
Concomitant

Drug Data