Leuprolide Acetate combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Other Serious 69 Male 3/15/2006 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/9/2005 79 Male 3/21/2006 Germany
Primary
Secondary
Rhabdomyolysis Hospitalization 12/9/2005 79 Male 3/30/2006 Germany
Primary
Secondary
Streptococcal Sepsis Hospitalization 3/3/2006 72 Male 306 lb 4/10/2006 Physician France
Primary
Concomitant
Weight Decreased Other Serious 1/10/2006 72 Male 150 lb 12/28/2006 Consumer United States
Primary
Concomitant
Mobility Decreased Other Serious Female 1/16/2007 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Disability 2/22/2006 73 Male 182 lb 4/16/2007 Physician Canada
Primary
Secondary
Concomitant
Sensory Loss Hospitalization 7/8/2007 64 Male 222 lb 9/13/2007 Physician United States
Primary
Secondary
Concomitant
Mobility Decreased Other Serious Female 7/30/2007 Consumer United States
Primary
Secondary
Concomitant
Purulent Discharge Other Serious 1/1/2007 54 Female 106 lb 10/18/2007 Physician Japan
Primary
Concomitant
Purulent Discharge Other Serious 1/1/2007 54 Female 106 lb 10/25/2007 Physician Japan
Primary
Concomitant
Purulent Discharge Other Serious 1/1/2007 54 Female 106 lb 10/31/2007 Japan
Primary
Concomitant
Purulent Discharge Other Serious 1/1/2007 54 Female 106 lb 11/13/2007 Japan
Primary
Concomitant
Paraneoplastic Syndrome Hospitalization 11/15/2007 73 Male 12/14/2007 Austria
Primary
Concomitant
X-ray Dental Hospitalization 3/26/2006 60 Male 4/10/2008 Italy
Primary
Concomitant
Osteomyelitis Other Serious 5/12/2007 87 Male 4/11/2008 Italy
Primary
Concomitant
Interstitial Lung Disease Death 6/12/2008 78 Male 130 lb 8/4/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 6/12/2008 78 Male 130 lb 8/26/2008 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 3/1/2007 Male 10/15/2008 Japan
Primary
Concomitant
Tooth Extraction Other Serious 3/1/2006 Male 11/7/2008 France
Primary
Concomitant
Osteonecrosis Other Serious Male 12/10/2008 Physician Italy
Primary
Concomitant
Stomatitis Other Serious 11/12/2008 Male 146 lb 1/2/2009 Physician Japan
Primary
Concomitant
Renal Impairment Disability 6/22/2007 Male 2/13/2009 Japan
Primary
Concomitant
Cerebral Infarction Life Threatening 11/21/2008 46 Female 90 lb 2/19/2009 Other Health Professional Japan
Primary
Concomitant
Tooth Extraction Other Serious 10/1/2008 Male 3/16/2009 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 10/1/2008 Male 3/19/2009 Physician Japan
Primary
Concomitant
Cerebral Infarction Life Threatening 11/21/2008 46 Female 90 lb 3/20/2009 Other Health Professional Japan
Primary
Concomitant
Purulent Discharge Other Serious 3/12/2009 76 Male 3/26/2009 Physician Japan
Primary
Concomitant
Osteonecrosis Disability 12/31/2008 68 Male 8/10/2009 Other Health Professional Italy
Primary
Concomitant
Osteonecrosis Disability 12/31/2008 68 Male 9/17/2009 Other Health Professional Italy
Primary
Concomitant
Osteomyelitis Other Serious 8/12/2008 Female 9/29/2009 Other Health Professional Italy
Primary
Concomitant
Surgery Other Serious 1/31/2007 Male 9/29/2009 Other Health Professional Italy
Primary
Concomitant
Surgery Other Serious 1/31/2007 Male 10/21/2009 Other Health Professional Italy
Primary
Concomitant
Osteomyelitis Other Serious 8/12/2008 Female 10/21/2009 Other Health Professional Italy
Primary
Concomitant
Cerebral Ischaemia Disability 10/28/2009 69 Male 192 lb 11/9/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Toothache Other Serious 3/7/2003 Female 127 lb 1/20/2010 Physician United States
Primary
Concomitant
Toothache Other Serious 3/7/2003 Female 127 lb 2/5/2010 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 7/25/2008 Male 2/10/2010 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 11/1/2005 Male 2/22/2010 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Other Serious 11/1/2008 Male 2/24/2010 Other Health Professional Italy
Primary
Concomitant
Toothache Other Serious 3/7/2003 Female 127 lb 2/26/2010 Physician United States
Primary
Concomitant
Prostate Cancer Stage Iv Death 10/29/2008 69 Male 2/26/2010 Japan
Primary
Concomitant
Osteonecrosis Other Serious 11/1/2008 Male 3/5/2010 Other Health Professional Italy
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2009 Male 3/11/2010 United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/14/2005 Female 127 lb 3/12/2010 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 11/1/2005 Male 3/22/2010 Other Health Professional United States
Primary
Concomitant
Tooth Infection Other Serious 1/7/2010 Male 3/24/2010 Other Health Professional France
Primary
Concomitant
Prostate Cancer Stage Iv Death Male 4/8/2010 Japan
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2009 79 Male 4/13/2010 United States
Primary
Secondary
Concomitant
Death Death 11/10/2008 87 Male 4/20/2010 Japan
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2009 79 Male 4/26/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/14/2005 55 Female 127 lb 5/7/2010 United States
Primary
Concomitant
Death Death 11/10/2008 87 Male 101 lb 5/13/2010 Japan
Primary
Concomitant
Breast Cancer Female Death 12/28/2009 34 Female 5/21/2010 Japan
Primary
Concomitant
Breast Cancer Female Death 12/28/2009 34 Female 99 lb 6/1/2010 Other Health Professional Japan
Primary
Concomitant
Weight Decreased Other Serious 4/14/2005 55 Female 127 lb 6/11/2010 United States
Primary
Concomitant
Weight Decreased 8/27/2007 67 Male 177 lb 6/23/2010 Other Health Professional United States
Primary
Concomitant
Tooth Infection Other Serious 1/7/2010 77 Male 6/25/2010 Other Health Professional France
Primary
Concomitant
Prostate Cancer Death 5/31/2009 46 Male 150 lb 6/29/2010 Physician Japan
Primary
Concomitant
Venous Pressure Jugular Increased Hospitalization 4/19/2010 55 Male 207 lb 7/14/2010 Physician United Kingdom
Primary
Concomitant
Venous Pressure Jugular Increased Hospitalization 1/21/2010 55 Male 207 lb 8/11/2010 Physician United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 11/1/2005 57 Male 8/24/2010 Other Health Professional United States
Primary
Concomitant
Venous Pressure Jugular Increased Hospitalization 1/21/2010 55 Male 207 lb 8/26/2010 Physician United Kingdom
Primary
Concomitant
Venous Pressure Jugular Increased Hospitalization 1/21/2010 55 Male 207 lb 9/9/2010 Physician United Kingdom
Primary
Concomitant
Prostate Cancer Stage Iv Death 12/21/2007 68 Male 9/14/2010 Other Health Professional Japan
Primary
Concomitant
Cardiac Failure Life Threatening 3/9/2009 71 Male 9/14/2010 Other Health Professional Japan
Primary
Concomitant
Breast Cancer Female Death 5/31/2008 53 Female 9/14/2010 Physician Japan
Primary
Concomitant
Cardiac Failure Life Threatening 3/9/2009 71 Male 121 lb 9/23/2010 Other Health Professional Japan
Primary
Concomitant
Prostate Cancer Stage Iv Death 1/21/2010 62 Male 9/24/2010 Physician Japan
Primary
Concomitant
Breast Cancer Female Death 5/31/2008 53 Female 114 lb 9/24/2010 Physician Japan
Primary
Concomitant
Prostate Cancer Stage Iv Death 12/21/2007 68 Male 10/1/2010 Other Health Professional Japan
Primary
Concomitant
Prostate Cancer Stage Iv Hospitalization 11/20/2007 65 Male 10/7/2010 Other Health Professional Japan
Primary
Concomitant
Prostate Cancer Stage Iv Death 55 Male 10/22/2010 Other Health Professional Japan
Primary
Concomitant
Urinary Incontinence Other Serious 11/1/2005 56 Male 10/28/2010 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Life Threatening 3/9/2009 71 Male 121 lb 10/28/2010 Other Health Professional Japan
Primary
Concomitant
Prostate Cancer Death 4/8/2010 83 Male 10/28/2010 Other Health Professional Japan
Primary
Concomitant
Prostate Cancer Stage Iv Hospitalization 11/20/2007 65 Male 11/5/2010 Other Health Professional Japan
Primary
Concomitant
Prostate Cancer Death 4/8/2010 83 Male 11/9/2010 Other Health Professional Japan
Primary
Concomitant
Pneumothorax Hospitalization 11/1/2009 69 Male 11/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Prostate Cancer Stage Iv Death 1/21/2010 62 Male 11/11/2010 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 8/1/2010 80 Male 183 lb 10/25/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Death 1/20/2009 82 Male 11/30/2010 Other Health Professional Japan
Primary
Concomitant
Lymphocyte Stimulation Test Positive Hospitalization 11/1/2009 69 Male 1/17/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 12/1/2010 62 Male 223 lb 1/10/2011 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 8/1/2010 62 Male 2/7/2011 Physician France
Primary
Concomitant
General Physical Health Deterioration Other Serious 4/6/2010 65 Male 201 lb 3/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Prostate Cancer Stage Iv Death 5/8/2010 78 Male 3/23/2011 Physician Japan
Primary
Concomitant
Bone Lesion Other Serious 1/7/2010 77 Male 4/1/2011 Other Health Professional France
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2010 49 Female 4/18/2011 Japan
Primary
Secondary
Concomitant
Retinal Vein Thrombosis Other Serious 7/27/2010 62 Male 5/16/2011 Physician France
Primary
Concomitant
Osteonecrosis Of Jaw Hospitalization Male 280 lb 5/30/2011 Physician Germany
Primary
Secondary
Concomitant
Bone Lesion Other Serious 1/7/2010 77 Male 5/24/2011 Other Health Professional France
Primary
Concomitant
Metastases To Central Nervous System Hospitalization 8/26/2009 32 Female 194 lb 6/9/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2010 49 Female 6/10/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2010 49 Female 6/10/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2010 49 Female 6/10/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2010 49 Female 6/10/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2010 49 Female 6/10/2011 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 5/3/2011 81 Male 157 lb 6/30/2011 Physician Australia
Primary
Secondary
Concomitant
Cholangitis Hospitalization 8/26/2009 32 Female 194 lb 7/1/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Cholesterol Increased Hospitalization 1/1/2011 46 Female 139 lb 7/12/2011 Pharmacist Turkey
Primary
Concomitant
Syncope Hospitalization 5/3/2011 81 Male 157 lb 7/13/2011 Physician Australia
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/3/2011 81 Male 157 lb 7/18/2011 Physician Australia
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/4/2011 70 Male 7/20/2011 Physician Australia
Primary
Secondary
Concomitant
Malaise Hospitalization 6/1/2011 80 Male 7/20/2011 Netherlands
Primary
Concomitant
Bone Disorder Other Serious 1/4/2011 75 Male 7/27/2011 Physician Japan
Primary
Concomitant
Blood Cholesterol Increased Hospitalization 1/1/2011 46 Female 139 lb 7/28/2011 Pharmacist Turkey
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 7/4/2011 70 Male 8/1/2011 Physician Australia
Primary
Secondary
Concomitant
Neoplasm Progression Death 12/8/2010 75 Male 8/2/2011 Pharmacist Netherlands
Primary
Concomitant
Renal Impairment Hospitalization 6/1/2011 80 Male 8/8/2011 Consumer Netherlands
Primary
Concomitant
Myocardial Infarction Life Threatening 7/4/2011 70 Male 8/11/2011 Physician Australia
Primary
Secondary
Concomitant
Haematochezia Death 1/22/2008 57 Male 157 lb 9/6/2011 Physician Japan
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious Male 9/11/2011 Other Health Professional France
Primary
Concomitant
Bone Fistula Other Serious 6/27/2011 67 Male 9/15/2011 Other Health Professional Italy
Primary
Concomitant
Pain Hospitalization 9/5/2011 57 Male 9/23/2011 Netherlands
Primary
Concomitant
Blood Urea Increased Other Serious 74 Male 10/4/2011 Japan
Primary
Concomitant
Arteriosclerosis Coronary Artery Hospitalization 3/5/2008 75 Male 10/14/2011 Physician Australia
Primary
Concomitant
Neoplasm Progression Other Serious 7/15/2011 84 Male 143 lb 10/19/2011 Netherlands
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 8/21/2011 76 Male 10/19/2011 Physician Japan
Primary
Concomitant
Hypotension Hospitalization 5/3/2011 81 Male 157 lb 11/2/2011 Physician Australia
Primary
Secondary
Concomitant
Device Occlusion Hospitalization 8/27/2010 55 Male 11/4/2011 Other Health Professional Netherlands
Primary
Concomitant
Cerebral Infarction Other Serious 8/21/2011 76 Male 11/9/2011 Physician Japan
Primary
Concomitant
Bone Pain Other Serious 10/18/2011 60 Male 11/9/2011 Netherlands
Primary
Concomitant
Interstitial Lung Disease Death 10/4/2011 77 Male 11/14/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/8/2011 71 Male 11/17/2011 Physician Japan
Primary
Concomitant
Mobility Decreased Hospitalization 9/4/2011 57 Male 11/21/2011 Other Health Professional Netherlands
Primary
Concomitant
Arthritis Hospitalization Male 11/22/2011 Other Health Professional Netherlands
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 5/1/2011 58 Male 209 lb 11/23/2011 Other Health Professional Germany
Primary
Concomitant
Hyperthyroidism Other Serious 1/1/2008 64 Male 11/29/2011 Other Health Professional Germany
Primary
Concomitant
Urinary Retention Hospitalization 5/20/2011 71 Male 12/6/2011 Physician Germany
Primary
Concomitant
Osteonecrosis Of Jaw Hospitalization 9/19/2011 64 Male 174 lb 12/8/2011 Consumer United States
Primary
Concomitant
Osteonecrosis Of Jaw Disability 43 Female 12/13/2011 Other Health Professional Switzerland
Primary
Concomitant
Death Death 83 Male 12/13/2011 Physician Germany
Primary
Concomitant
Hepatomegaly Death 10/28/2011 34 Female 152 lb 12/19/2011 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Death 83 Male 12/27/2011 Physician Germany
Primary
Concomitant
Gastric Cancer Death 82 Male 12/28/2011 Physician Germany
Primary
Concomitant
Asthenia Hospitalization 9/4/2011 57 Male 12/29/2011 Physician Netherlands
Primary
Concomitant
Drug Intolerance Hospitalization 11/1/2011 77 Male 12/30/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastric Cancer Death 82 Male 132 lb 12/30/2011 Physician Germany
Primary
Concomitant
Cardiac Failure Death 83 Male 143 lb 12/30/2011 Physician Germany
Primary
Concomitant
Haemoglobin Decreased Other Serious 12/3/2011 66 Male 12/31/2011 Physician Japan
Primary
Concomitant
Pain Death 11/1/2011 65 Male 1/2/2012 Other Health Professional Netherlands
Primary
Concomitant
Neck Pain Other Serious 10/10/2011 60 Male 1/3/2012 Netherlands
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 12/3/2011 66 Male 1/6/2012 Pharmacist Japan
Primary
Concomitant
Necrotising Fasciitis Hospitalization 8/27/2010 55 Male 1/9/2012 Netherlands
Primary
Concomitant
Haemoglobin Decreased Hospitalization 5/1/2011 67 Male 141 lb 1/12/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Pain In Jaw Death 5/1/2011 67 Male 141 lb 1/12/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Tooth Abscess Other Serious Male 1/19/2012 Lawyer United States
Primary
Secondary
Concomitant
Aphasia Hospitalization 1/15/2012 67 Male 1/24/2012 Netherlands
Primary
Concomitant
Terminal State Other Serious 4/1/2011 76 Male 1/25/2012 Other Health Professional Netherlands
Primary
Concomitant

Drug Data