Leucovorin Calcium combined with Zofran

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Life Threatening 5/30/2005 Male 235 lb 1/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/5/2005 57 Male 1/13/2006 Physician United States
Primary
Concomitant
Tremor Hospitalization 11/21/2005 56 Female 106 lb 1/13/2006 Physician Canada
Primary
Secondary
Concomitant
Tremor Hospitalization 11/21/2005 56 Female 106 lb 1/18/2006 Physician Canada
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/28/2005 42 Female 205 lb 1/18/2006 Physician Canada
Primary
Secondary
Concomitant
Gastritis Hospitalization 9/11/2005 57 Female 180 lb 1/20/2006 Physician Germany
Primary
Secondary
Concomitant
Scab Other Serious 55 Male 2/1/2006 Physician Netherlands
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/11/2005 63 Male 2/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Life Threatening 1/31/2006 Male 194 lb 2/28/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 2/15/2006 64 Male 243 lb 3/7/2006 Physician United States
Primary
Secondary
Concomitant
Tremor Life Threatening 2/14/2006 Male 3/16/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 2/15/2006 64 Male 243 lb 3/21/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/8/2005 55 Male 181 lb 3/30/2006 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/13/2006 55 Male 128 lb 4/12/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/17/2006 63 Female 102 lb 5/5/2006 Physician United States
Primary
Secondary
Concomitant
Gastritis Hospitalization 9/11/2005 57 Female 180 lb 5/11/2006 Other Health Professional Germany
Primary
Concomitant
Weight Decreased Hospitalization 1/13/2006 55 Male 128 lb 5/10/2006 Physician France
Primary
Secondary
Concomitant
Vision Blurred 2/6/2006 56 Male 3/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
Duodenal Perforation Required Intervention 2/12/2006 81 Male 143 lb 3/1/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 57 Female 5/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 11/21/2005 56 Female 106 lb 5/16/2006 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/7/2006 70 Female 5/12/2006 United States
Primary
Secondary
Concomitant
Nasal Septum Perforation Other Serious 55 Male 6/5/2006 Physician Netherlands
Primary
Concomitant
Pruritus Other Serious 5/22/2006 56 Male 7/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 61 Male 179 lb 5/31/2006 Physician United States
Primary
Concomitant
Swelling Other Serious 7/1/2006 56 Male 7/31/2006 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/24/2006 72 Male 137 lb 8/7/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Other Serious 6/30/2006 56 Male 8/23/2006 Physician United States
Primary
Concomitant
Dermatitis Acneiform 6/1/2006 60 Male 8/29/2006 Pharmacist United States
Primary
Concomitant
Disease Progression Death 12/7/2004 Male 116 lb 7/24/2006 Physician United States
Primary
Concomitant
Pyrexia Death 1/1/2006 80 Male 10/27/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/4/2005 Female 170 lb 10/24/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/19/2005 65 Male 10/25/2006 Physician Ireland
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 5/26/2006 Female 167 lb 11/15/2006 Physician United States
Primary
Concomitant
Dysphagia Hospitalization 1/24/2005 Male 168 lb 11/17/2006 Other Health Professional France
Primary
Secondary
Concomitant
Epilepsy Other Serious 11/6/2006 Male 247 lb 11/17/2006 Physician Germany
Primary
Secondary
Concomitant
Epilepsy Other Serious 10/23/2006 Male 247 lb 11/17/2006 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/4/2006 Male 11/22/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 57 Female 1/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 10/1/2001 62 Female 140 lb 2/10/2007 United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 2/4/2006 Male 2/16/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 8/31/2006 Female 105 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/9/2007 Male 158 lb 2/22/2007 United States
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 1/19/2007 73 Male 2/16/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 2/9/2007 Male 158 lb 3/2/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/9/2007 Male 158 lb 3/13/2007 United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 2/4/2006 Male 3/14/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/9/2007 Male 158 lb 3/16/2007 Other Health Professional
Primary
Secondary
Concomitant
Oxygen Saturation Decreased 7/1/2004 Male 220 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/11/2005 63 Male 3/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/9/2007 Male 158 lb 3/30/2007 Other Health Professional
Primary
Secondary
Concomitant
Tracheal Disorder Hospitalization 2/6/2007 70 Male 172 lb 3/28/2007 Physician United States
Primary
Secondary
Concomitant
Tracheal Disorder Hospitalization 2/6/2007 71 Male 172 lb 3/29/2007 Physician United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 2/26/2007 Male 173 lb 4/11/2007 Physician United States
Primary
Concomitant
Palpitations Other Serious 7/12/2006 Male 4/17/2007 Physician
Primary
Concomitant
Drug Interaction Other Serious 2/22/2007 14 Male 62 lb 4/12/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/24/2007 Female 112 lb 4/27/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 5/24/2006 Male 159 lb 5/7/2007 Other Health Professional France
Primary
Secondary
Concomitant
Drug Interaction Other Serious 2/22/2007 14 Male 62 lb 5/2/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 4/28/2007 Female 195 lb 5/7/2007 United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 5/15/2007 Male 205 lb 5/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 52 Female 6/6/2007 Consumer United States
Primary
Concomitant
Ileus Hospitalization 3/1/2007 Male 6/13/2007 Physician Austria
Primary
Secondary
Concomitant
Death Death 5/24/2006 Male 159 lb 6/14/2007 Other Health Professional France
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/22/2005 Male 6/15/2007 Physician United States
Primary
Secondary
Concomitant
Impetigo Hospitalization 6/4/2007 Male 6/28/2007 Physician Hungary
Primary
Concomitant
Myocardial Infarction Life Threatening 1/24/2007 Female 112 lb 6/28/2007 Physician United States
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 4/11/2007 Female 145 lb 7/9/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Impetigo Hospitalization 6/4/2007 Male 7/18/2007 Physician Hungary
Primary
Concomitant
Rash Generalised 6/14/2007 Female 7/23/2007 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 4/7/2004 Male 2461 lb 7/23/2007 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/26/2007 Male 236 lb 7/30/2007 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 8/14/2007 Female 165 lb 8/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 5/15/2007 Male 205 lb 8/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Perirectal Abscess Hospitalization 7/19/2007 Female 127 lb 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/16/2007 41 Female 8/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Impetigo Hospitalization 5/29/2007 Male 8/31/2007 Physician Hungary
Primary
Concomitant
Stomatitis Hospitalization 7/22/2007 Female 9/6/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 8/14/2007 Female 165 lb 11/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ileus Hospitalization 3/1/2007 Male 11/29/2007 Physician Austria
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 10/15/2007 41 Female 11/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Gastritis Hospitalization 9/11/2005 Female 180 lb 11/30/2007 Physician United Kingdom
Primary
Concomitant
Syncope Hospitalization 8/14/2007 Female 165 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 10/15/2007 41 Female 12/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 2/22/2007 14 Male 62 lb 11/29/2007 Physician Germany
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 10/15/2007 41 Female 12/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 11/28/2007 42 Female 159 lb 12/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/22/2007 Female 12/20/2007 Physician United States
Primary
Secondary
Concomitant
Urticaria Required Intervention 12/14/2007 29 Female 140 lb 12/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/9/2007 Male 224 lb 2/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Petechiae Other Serious 7/23/2007 Female 179 lb 3/10/2008 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 1/15/2008 Male 3/12/2008 Physician Hungary
Primary
Concomitant
Coronary Artery Stenosis Life Threatening 10/8/2007 Male 263 lb 3/25/2008 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 3/14/2008 Female 3/26/2008 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 3/15/2008 43 Female 128 lb 3/26/2008 Pharmacist United States
Primary
Concomitant
Influenza Like Illness 12/1/2007 Male 171 lb 3/28/2008 Physician United States
Primary
Concomitant
Pain 5/30/2007 53 Female 3/28/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 1/15/2008 Male 3/31/2008 Physician Hungary
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 2/26/2008 Female 119 lb 4/1/2008 Physician United States
Primary
Concomitant
Gallbladder Perforation Hospitalization 4/11/2007 Female 145 lb 4/4/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 3/14/2008 Female 113 lb 4/10/2008 Physician Canada
Primary
Concomitant
Hypersensitivity 3/12/2008 57 Male 4/11/2008 Other Health Professional United States
Primary
Concomitant
Rectal Haemorrhage Death 3/8/2008 Male 4/14/2008 Physician France
Primary
Concomitant
Intra-abdominal Haemorrhage Death 4/1/2008 Male 201 lb 4/17/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 3/14/2008 Female 113 lb 5/1/2008 Physician Canada
Primary
Concomitant
Rectal Haemorrhage Death 3/8/2008 Male 5/14/2008 Physician France
Primary
Concomitant
Hypersensitivity 3/12/2008 57 Male 5/15/2008 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Hospitalization 4/30/2008 Male 143 lb 5/15/2008 Physician United Kingdom
Primary
Concomitant
Cholecystitis Hospitalization 4/11/2007 Female 145 lb 5/20/2008 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Perforation Death 4/1/2008 Male 201 lb 5/28/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Hypotension Other Serious 2/13/2008 72 Male 6/4/2008 Physician Bulgaria
Primary
Secondary
Insomnia Disability 4/20/2007 61 Male 5/23/2008 Physician United States
Primary
Concomitant
Hypersensitivity Other Serious 2/26/2008 Female 119 lb 6/12/2008 Physician United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 3/28/2008 Male 134 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 2/26/2008 Female 119 lb 6/17/2008 Physician United States
Primary
Concomitant
Cardiac Disorder Other Serious 1/14/2007 Male 7/18/2008 Physician Canada
Primary
Secondary
Concomitant
Cardiac Disorder Other Serious 1/14/2007 57 Female 7/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Shock Haemorrhagic Hospitalization 3/28/2008 Male 134 lb 7/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 3/31/2008 Male 134 lb 7/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 5/31/2008 50 Male 220 lb 8/1/2008 Consumer United States
Primary
Secondary
Concomitant
Cardiac Disorder Other Serious 1/14/2007 57 Female 8/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 5/15/2007 Male 205 lb 8/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 3/28/2008 Male 134 lb 8/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/29/2008 Female 114 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 8/15/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 1/14/2007 Male 10/10/2008 Physician Canada
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 1/14/2007 Female 10/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/29/2008 Female 114 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 10/16/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 1/14/2007 Male 10/23/2008 Physician Canada
Primary
Secondary
Concomitant
Shock Other Serious 11/30/2007 Male 35 lb 11/3/2008 Other Health Professional Brazil
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/18/2008 Male 57 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Other Serious 5/21/2008 Male 194 lb 11/4/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Disease Progression Death 5/8/2008 Female 157 lb 11/10/2008 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/19/2007 Male 11/14/2008 Consumer Japan
Primary
Secondary
Concomitant
Delirium Febrile Hospitalization 11/5/2008 Male 12/3/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Shock Other Serious 4/7/2008 67 Female 12/10/2008 Pharmacist Canada
Primary
Concomitant
Shock Haemorrhagic Life Threatening 3/28/2008 Male 134 lb 12/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 8/20/2008 Male 12/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 3/31/2008 Male 134 lb 12/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Delirium Febrile Hospitalization 11/5/2008 Male 12/31/2008 Other Health Professional Canada
Primary
Secondary
Concomitant

Drug Data