Leucovorin Calcium combined with Vincristine Sulfate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Stomatitis Other Serious 11/21/2005 Female 138 lb 1/17/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/11/2006 Female 214 lb 4/28/2006 United States
Primary
Secondary
Pyrexia Other Serious 5/8/2006 Female 122 lb 6/7/2006 United States
Primary
Secondary
Mucosal Inflammation Hospitalization 7/31/2006 Male 168 lb 8/1/2006 United States
Primary
Secondary
Tachycardia Hospitalization 3/4/2006 Male 311 lb 8/11/2006 United States
Primary
Secondary
Pain Hospitalization 9/21/2006 Male 168 lb 10/11/2006 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 10/9/2006 Male 52 lb 10/20/2006 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 10/9/2006 Male 52 lb 11/22/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 11/16/2006 Male 136 lb 11/17/2006 United States
Primary
Secondary
Vomiting Hospitalization 12/10/2006 Female 100 lb 12/13/2006 United States
Primary
Secondary
Small Intestinal Obstruction Hospitalization 12/3/2006 Female 147 lb 12/15/2006 United States
Primary
Secondary
Vomiting Hospitalization 12/10/2006 Female 100 lb 1/12/2007 United States
Primary
Secondary
Aspartate Aminotransferase Increased Hospitalization 8/31/2006 Female 105 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/19/2007 Male 198 lb 5/8/2007 United States
Primary
Secondary
Treatment Noncompliance Hospitalization 4/27/2007 Male 194 lb 5/8/2007 United States
Primary
Secondary
Tachycardia Hospitalization 6/3/2007 Male 188 lb 6/8/2007 United States
Primary
Secondary
Nephropathy Toxic Other Serious 4/1/2005 13 Male 7/2/2007 Other Health Professional United States
Primary
Secondary
Osteoarthritis Hospitalization 6/22/2007 Female 229 lb 7/5/2007 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 7/18/2007 Female 141 lb 7/20/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/25/2007 Male 187 lb 7/30/2007 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 7/17/2007 Male 234 lb 8/23/2007 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/6/2007 Male 200 lb 9/14/2007 United States
Primary
Secondary
Tumour Lysis Syndrome Hospitalization 9/18/2007 Male 492 lb 10/2/2007 United States
Primary
Secondary
Mucosal Inflammation Hospitalization 10/5/2007 Female 64 lb 10/9/2007 United States
Primary
Secondary
Wound Secretion Hospitalization 9/27/2007 Male 467 lb 10/8/2007 United States
Primary
Secondary
Depressed Level Of Consciousness 10/16/2007 Female 114 lb 10/22/2007 United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 10/15/2007 Female 229 lb 10/26/2007 United States
Primary
Secondary
Pharyngolaryngeal Pain Hospitalization 10/5/2007 Female 64 lb 10/30/2007 United States
Primary
Secondary
Pharyngolaryngeal Pain Hospitalization 10/5/2007 Female 64 lb 11/4/2007 United States
Primary
Secondary
Pulmonary Embolism Hospitalization 11/9/2007 Male 175 lb 11/19/2007 United States
Primary
Secondary
Tongue Biting Hospitalization 11/9/2007 Male 203 lb 11/20/2007 United States
Primary
Secondary
Swelling Face Hospitalization 10/31/2007 Male 291 lb 11/20/2007 United States
Primary
Secondary
Pyrexia Hospitalization 11/29/2007 Male 291 lb 12/4/2007 United States
Primary
Secondary
Vomiting Other Serious 11/11/2007 Male 289 lb 12/4/2007 United States
Primary
Secondary
Pseudomonas Infection Hospitalization 12/12/2007 Female 166 lb 1/2/2008 United States
Primary
Secondary
Tachycardia Hospitalization 12/21/2007 Male 289 lb 1/7/2008 United States
Primary
Secondary
Treatment Noncompliance Hospitalization 2/19/2008 Male 187 lb 2/28/2008 United States
Primary
Secondary
Hypocalcaemia Hospitalization 3/4/2008 Male 183 lb 5/8/2008 United States
Primary
Secondary
Odynophagia Hospitalization 9/30/2006 Male 61 lb 7/10/2008 United States
Primary
Secondary
Malabsorption 7/28/2008 Male 125 lb 7/28/2008 United States
Primary
Secondary
Oedema Peripheral Hospitalization 7/6/2008 Female 134 lb 7/29/2008 United States
Primary
Secondary
Transient Ischaemic Attack Hospitalization 7/22/2008 9 Male 76 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Wound Infection Bacterial Hospitalization 5/27/2007 Female 141 lb 6/20/2007 United States
Primary
Secondary
Renal Failure Acute Hospitalization 2/28/2008 Female 234 lb 3/6/2008 United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 9/15/2008 Consumer France
Primary
Secondary
Concomitant
Urine Leukocyte Esterase Positive Hospitalization 10/5/2008 Male 209 lb 10/9/2008 United States
Primary
Secondary
Gamma-glutamyltransferase Increased 10/20/2008 Male 104 lb 10/22/2008 United States
Primary
Secondary
Stomatitis Hospitalization 10/18/2008 Male 159 lb 10/20/2008 United States
Primary
Secondary
Rash Macular Hospitalization 11/5/2007 Female 190 lb 11/10/2008 United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 11/24/2008 Consumer France
Primary
Secondary
Concomitant
Death Death 67 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 66 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Sinusitis Other Serious 4/1/2002 12/17/2008 Other Health Professional France
Primary
Secondary
Concomitant
Wheezing Hospitalization 6/30/2005 Female 139 lb 1/5/2009 United States
Primary
Secondary
Urine Leukocyte Esterase Positive Hospitalization 11/23/2008 Male 209 lb 1/8/2009 United States
Primary
Secondary
Pharyngeal Oedema Hospitalization 12/27/2008 Male 183 lb 12/30/2008 United States
Primary
Secondary
Stomatitis Hospitalization 11/24/2008 Male 36 lb 1/13/2009 United States
Primary
Secondary
Sepsis Hospitalization 11/15/2008 Male 192 lb 2/9/2009 United States
Primary
Secondary
Weight Decreased Hospitalization 10/6/2008 Male 192 lb 2/11/2009 United States
Primary
Secondary
Type 2 Diabetes Mellitus Hospitalization 1/14/2009 Male 260 lb 2/18/2009 United States
Primary
Secondary
No Therapeutic Response Hospitalization 2/6/2009 Female 41 lb 3/4/2009 United States
Primary
Secondary
No Therapeutic Response Hospitalization 2/6/2009 Female 41 lb 3/16/2009 United States
Primary
Secondary
Soft Tissue Disorder Hospitalization 4/1/2009 Male 176 lb 4/6/2009 United States
Primary
Secondary
Pyrexia Hospitalization 5/2/2009 Male 157 lb 5/19/2009 United States
Primary
Secondary
Vomiting Hospitalization 7/5/2009 Male 163 lb 7/13/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/12/2009 Male 163 lb 6/23/2009 United States
Primary
Secondary
Vomiting Hospitalization 7/19/2009 Male 104 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/19/2009 Male 104 lb 7/24/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/28/2009 Female 30 lb 8/14/2009 United States
Primary
Secondary
Ventricular Extrasystoles Hospitalization 8/12/2009 Male 254 lb 8/19/2009 United States
Primary
Secondary
Vomiting Hospitalization 10/29/2009 Female 99 lb 11/13/2009 United States
Primary
Secondary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/8/2010 51 Female 147 lb 4/19/2010 United States
Primary
Secondary
Pulmonary Embolism Hospitalization 4/8/2010 51 Female 147 lb 4/20/2010 United States
Primary
Secondary
Paraesthesia Other Serious 13 Male 88 lb 5/3/2010 Other Health Professional Canada
Primary
Concomitant
Urticaria Required Intervention 3/18/2010 38 Female 5/21/2010 Pharmacist Canada
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 7/31/2010 44 Female 250 lb 8/6/2010 United States
Primary
Secondary
Neuropathy Peripheral Other Serious 2 Male 33 lb 8/2/2010 Other Health Professional Canada
Primary
Concomitant
Neutropenic Sepsis Death 10/25/2010 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 10/25/2010 Other Health Professional United States
Primary
Secondary
Neuropathy Peripheral Other Serious 10/25/2010 Other Health Professional United States
Primary
Secondary
Neuropathy Peripheral Other Serious 10/25/2010 Other Health Professional United States
Primary
Secondary
Burning Sensation Hospitalization Male 101 lb 3/3/2011 Other Health Professional Canada
Primary
Concomitant
Renal Failure Death 72 Female 174 lb 3/9/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/21/2011 16 Female 4/18/2011 Physician Spain
Primary
Secondary
Concomitant
Bone Marrow Failure Death 5/5/2011 Physician United States
Primary
Secondary
Concomitant
Infection In An Immunocompromised Host Other Serious 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Death 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Marrow Failure Death 5/5/2011 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 5/5/2011 Physician United States
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 5/5/2011 Physician United States
Primary
Secondary
Concomitant
Bone Marrow Failure Death 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Infection In An Immunocompromised Host Death 5/5/2011 Physician United States
Primary
Secondary
Concomitant
Candidiasis Hospitalization 4/1/2009 49 Male 128 lb 4/26/2011 United States
Primary
Secondary
Concomitant
Infection Hospitalization 11/2/2010 18 Male 124 lb 5/13/2011 Physician United States
Primary
Secondary
Acute Lymphocytic Leukaemia Hospitalization 4/8/2011 10 Male 90 lb 5/11/2011 United States
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Other Health Professional India
Primary
Secondary
Pregnancy Other Serious Female 7/14/2011 Physician India
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Physician India
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Physician India
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Physician India
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Physician India
Primary
Secondary
Pregnancy Other Serious Female 7/14/2011 Other Health Professional India
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Other Health Professional India
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Other Health Professional India
Primary
Secondary
General Physical Health Deterioration Hospitalization 9/10/2011 7 Male 57 lb 9/12/2011 Physician United States
Primary
Secondary
B-cell Lymphoma Other Serious 8/4/2011 48 Male 9/22/2011 Consumer United Kingdom
Primary
Concomitant
Aspergillosis Oral Hospitalization 9/11/2011 4 Female 40 lb 9/27/2011 United States
Primary
Secondary
Myelodysplastic Syndrome Hospitalization 3/9/2011 43 Male 202 lb 9/29/2011 United States
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 3/9/2011 43 Male 202 lb 9/29/2011 United States
Primary
Secondary
Neutropenia Other Serious 41 Female 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 26 Male 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 54 Female 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 51 Male 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 22 Female 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 49 Female 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 53 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 69 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 36 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 18 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 26 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Death 41 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 54 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 22 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 49 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 36 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Death 51 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 33 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 52 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Hepatitis B Other Serious 9/15/2011 47 Male 137 lb 12/1/2011 Other Health Professional France
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 11/14/2011 10 Female 60 lb 12/5/2011 Physician United States
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 11/19/2011 3 Male 29 lb 12/5/2011 Physician United States
Primary
Secondary
Pancreatitis Hospitalization 12/15/2011 9 Male 69 lb 12/16/2011 United States
Primary
Secondary
Tumour Lysis Syndrome Other Serious 39 Female 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/19/2011 31 Male 1/24/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Shock 12/4/2011 4 Female 32 lb 1/24/2012 United States
Primary
Secondary
Leukoencephalopathy Death 49 Male 2/10/2012 Physician Korea, Democratic People's Republic Of
Primary
Secondary
Alanine Aminotransferase Increased Other Serious 12/9/2011 48 Female 121 lb 2/18/2012 Consumer United States
Primary
Secondary
Pancreatitis Acute Hospitalization 12/17/2011 57 Female 3/5/2012 Other Health Professional France
Primary
Secondary
General Physical Health Deterioration Death 2/12/2012 16 Male 3/13/2012 Other Health Professional France
Primary
Secondary
Concomitant
Cytokine Storm Hospitalization 1/3/2012 42 Male 257 lb 3/20/2012 United States
Primary
Secondary

Drug Data