Leucovorin Calcium combined with Protonix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 Female 169 lb 5/3/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 Male 250 lb 5/3/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 67 Male 250 lb 5/10/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/2/2006 Female 169 lb 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Perforated Ulcer Hospitalization 5/18/2006 Female 169 lb 5/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 Male 250 lb 5/10/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/7/2006 70 Female 5/12/2006 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 9/26/2004 65 Female 370 lb 5/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2006 65 Female 5/30/2006 United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 81 Female 130 lb 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 67 Male 250 lb 5/31/2006 Consumer United States
Primary
Secondary
Concomitant
X-ray Of Pelvis And Hip Abnormal Life Threatening 5/2/2006 81 Female 139 lb 6/2/2006 Other Health Professional United States
Primary
Concomitant
Vascular Occlusion Life Threatening 5/2/2006 81 Female 139 lb 6/2/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Life Threatening 65 Female 169 lb 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/28/2006 Female 169 lb 7/3/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/2/2006 81 Female 139 lb 7/7/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 81 Female 130 lb 7/7/2006 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 11/22/2005 68 Female 132 lb 5/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 67 Male 250 lb 7/19/2006 United States
Primary
Secondary
Concomitant
Tumour Associated Fever Hospitalization 7/15/2006 Male 190 lb 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Stent Placement Life Threatening 5/1/2006 65 Female 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/15/2006 53 Male 190 lb 8/2/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/15/2006 53 Male 190 lb 8/21/2006 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/15/2006 53 Male 190 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 9/14/2006 52 Female 161 lb 10/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 10/24/2006 60 Male 203 lb 10/25/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 8/14/2006 Male 160 lb 12/4/2006 Physician United States
Primary
Concomitant
Urinary Retention Hospitalization 6/7/2005 Male 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 153 lb 1/19/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 153 lb 2/20/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 2/20/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 67 Male 250 lb 2/28/2007 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/14/2005 Male 210 lb 3/28/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 8/17/2003 Male 152 lb 4/5/2007 United States
Primary
Secondary
Intestinal Obstruction Other Serious 8/17/2003 57 Male 152 lb 4/16/2007 United States
Primary
Secondary
Intestinal Obstruction Hospitalization 8/18/2003 58 Male 152 lb 4/17/2007 United States
Primary
Secondary
Septic Shock Hospitalization 3/31/2006 Male 4/20/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/17/2003 Male 152 lb 4/27/2007 Physician United States
Primary
Secondary
Intestinal Obstruction Other Serious 8/17/2003 57 Male 4/30/2007 Physician United States
Primary
Secondary
Intestinal Obstruction Other Serious 8/17/2003 Male 152 lb 4/17/2007 United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 8/17/2003 57 Male 4/25/2007 United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 3/31/2006 Male 5/14/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 8/18/2003 58 Male 152 lb 7/12/2007 United States
Primary
Secondary
Intestinal Obstruction Other Serious 8/17/2003 57 Male 152 lb 7/19/2007 United States
Primary
Secondary
Sepsis Hospitalization 6/19/2007 53 Female 139 lb 7/20/2007 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 6/1/2007 48 Female 160 lb 7/25/2007 United States
Primary
Concomitant
Vomiting Other Serious 8/10/2007 41 Female 8/27/2007 Consumer United States
Primary
Concomitant
Perirectal Abscess Hospitalization 7/19/2007 Female 127 lb 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 7/17/2007 Male 234 lb 8/23/2007 United States
Primary
Secondary
Concomitant
Ureteric Obstruction Hospitalization 8/9/2007 55 Female 179 lb 9/10/2007 Other Health Professional United States
Primary
Secondary
Ureteric Obstruction Hospitalization 8/9/2007 55 Female 9/21/2007 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 8/9/2007 55 Female 9/17/2007 United States
Primary
Secondary
Ureteric Obstruction Hospitalization 8/9/2007 55 Female 10/2/2007 United States
Primary
Secondary
Ureteric Obstruction Hospitalization 8/9/2007 55 Female 10/11/2007 Physician United States
Primary
Secondary
Rash Macular Hospitalization 11/5/2007 Female 190 lb 11/6/2007 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 2/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 1/1/2008 Female 2/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 2/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Required Intervention 6/14/2006 78 Female 1/17/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2006 Female 3/31/2008 Pharmacist United States
Primary
Concomitant
Intestinal Obstruction Other Serious 8/17/2003 57 Male 4/9/2008 United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 8/17/2003 57 Male 4/9/2008 United States
Primary
Secondary
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 6/9/2008 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 6/23/2008 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 7/16/2008 Physician France
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 7/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 7/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 11/12/2007 59 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/7/2007 59 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/9/2007 55 Female 8/12/2008 United States
Primary
Secondary
Perinephric Collection Hospitalization 8/9/2007 55 Female 8/15/2008 United States
Primary
Secondary
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 9/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Macular Hospitalization 11/5/2007 Female 190 lb 11/10/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/8/2008 Female 194 lb 1/8/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/8/2008 Female 194 lb 1/23/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 1/28/2009 Male 169 lb 2/26/2009 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 3/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Necrosis Hospitalization 9/14/2006 Female 239 lb 3/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 11/12/2007 59 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/7/2007 59 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/28/2009 Male 169 lb 3/30/2009 Consumer United States
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 8/17/2003 57 Male 152 lb 3/26/2009 United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 4/8/2009 Male 4/24/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/8/2008 Female 194 lb 4/30/2009 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/17/2009 Male 174 lb 5/26/2009 United States
Primary
Secondary
Concomitant
Ill-defined Disorder 5/1/2009 Female 170 lb 6/12/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 10/1/2009 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 10/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 11/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 12/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 12/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 12/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 12/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 1/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 1/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 1/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 1/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 1/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 6/12/2009 Male 244 lb 6/19/2009 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 8/1/2005 Male 2/22/2010 Physician United States
Primary
Concomitant
Wheezing Hospitalization 11/20/2003 61 Female 140 lb 5/18/2010 Lawyer United States
Primary
Secondary
Concomitant
Lymphadenitis Hospitalization 6/10/2010 44 Female 123 lb 6/17/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/9/2010 40 Female 144 lb 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/9/2010 40 Female 7/20/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 134 lb 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
No Adverse Event 7/7/2007 53 Male 213 lb 7/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 134 lb 8/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 134 lb 9/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Lymphadenitis Hospitalization 6/10/2010 44 Female 123 lb 10/19/2010 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Disease Life Threatening 68 Male 226 lb 2/7/2011 Physician United States
Primary
Concomitant
Cardiac Arrest Death 1/21/2009 52 Female 151 lb 7/13/2011 Physician United States
Primary
Secondary
Concomitant
Dysstasia Other Serious 10/1/2006 58 Male 145 lb 8/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Colon Cancer Other Serious 1/2/2008 34 Female 10/17/2011 Consumer United States
Primary
Concomitant
Neoplasm Malignant Hospitalization 1/2/2008 34 Female 10/24/2011 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 10/27/2011 62 Male 11/2/2011 Physician United States
Primary
Concomitant
Leukocytosis Other Serious 1/1/2005 64 Male 179 lb 11/2/2011 Physician United States
Primary
Concomitant
Bronchitis 8/26/2011 57 Female 155 lb 11/6/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 1/18/2011 47 Female 11/17/2011 Pharmacist United States
Primary
Concomitant
Plasma Protein Metabolism Disorder Other Serious Male 11/24/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/19/2005 46 Female 120 lb 12/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyskinesia Hospitalization 1/2/2008 34 Female 12/14/2011 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 10/27/2011 62 Male 12/15/2011 Physician United States
Primary
Concomitant
Fatigue Hospitalization 9/19/2011 31 Male 12/19/2011 United States
Primary
Secondary
Concomitant
Breast Cancer Metastatic Hospitalization 1/2/2008 34 Female 1/1/2012 Lawyer United States
Primary
Concomitant
Radicular Cyst Death 12/1/2007 68 Male 1/6/2012 Physician United States
Primary
Concomitant
Lymphadenopathy Other Serious 12/1/2007 68 Male 1/9/2012 Physician United States
Primary
Concomitant
Sinus Tachycardia Other Serious Female 160 lb 1/4/2012 Lawyer United States
Primary
Concomitant
Staphylococcal Sepsis Death 12/1/2007 68 Male 1/13/2012 Physician United States
Primary
Concomitant
Colon Cancer Metastatic Hospitalization 1/2/2008 34 Female 1/23/2012 Consumer United States
Primary
Concomitant
Gout Hospitalization 12/1/2007 68 Male 1/24/2012 Physician United States
Primary
Concomitant
Mental Status Changes Hospitalization 10/27/2011 62 Male 1/25/2012 Physician United States
Primary
Concomitant
Hypotension Hospitalization 9/19/2011 31 Male 1/30/2012 Physician United States
Primary
Secondary
Concomitant
Device Malfunction 9/26/2011 68 Male 1/28/2012 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 12/1/2007 68 Male 2/6/2012 Lawyer United States
Primary
Concomitant
Fall Other Serious 12/1/2007 68 Male 3/8/2012 Physician United States
Primary
Concomitant
Electrocardiogram Qrs Complex Prolonged Hospitalization 12/1/2007 68 Male 4/24/2012 Lawyer United States
Primary
Concomitant
Ascites Hospitalization 3/12/2012 32 Male 183 lb 5/3/2012 Consumer United States
Primary
Secondary
Concomitant
Polyarthritis Hospitalization 3/16/2012 50 Male 375 lb 5/23/2012 Physician United States
Primary
Secondary
Concomitant
Migraine Hospitalization 1/2/2008 34 Female 5/29/2012 Consumer United States
Primary
Concomitant

Drug Data