Leucovorin Calcium combined with Prednisone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 6/5/2005 57 Male 1/13/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/29/2001 55 Female 148 lb 1/20/2006 Lawyer United States
Primary
Concomitant
Ureteral Disorder Hospitalization 12/30/2005 25 Female 1/26/2006 Argentina
Primary
Concomitant
Nephrolithiasis Hospitalization 2/17/2006 46 Female 129 lb 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 10/10/2005 70 Male 181 lb 2/17/2006 Physician France
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 1/1/1999 37 Female 148 lb 2/28/2006 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 1/31/2006 Male 194 lb 2/28/2006 Physician United States
Primary
Secondary
Concomitant
Rib Fracture Other Serious Female 135 lb 6/14/2006 Other Health Professional Canada
Primary
Concomitant
Lung Adenocarcinoma Hospitalization 12/12/2005 Male 8/1/2006 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 4/20/2006 Female 148 lb 8/10/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/21/2006 Female 139 lb 9/22/2006 Physician Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 153 lb 1/19/2007 Physician United States
Primary
Concomitant
Malignant Melanoma Other Serious Female 2/1/2007 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 153 lb 2/20/2007 Physician United States
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 8/31/2006 Female 105 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Other Serious 4/26/2006 Female 2/28/2007 Other Health Professional Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 3/21/2006 Female 163 lb 3/6/2007 United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 10/1/2005 52 Male 182 lb 4/2/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/6/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 3/31/2007 Female 7/13/2007 Other Health Professional Canada
Primary
Concomitant
Toothache Other Serious 1/25/2005 41 Female 244 lb 7/16/2007 United States
Primary
Secondary
Concomitant
Bradycardia Hospitalization 7/5/2007 Female 176 lb 7/18/2007 Other Health Professional United States
Primary
Concomitant
Muscular Weakness Other Serious 47 Female 9/10/2007 Other Health Professional Canada
Primary
Concomitant
Atrioventricular Block Second Degree Hospitalization 7/5/2007 Female 176 lb 9/21/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 8 Male 10/2/2007
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 9/18/2007 Male 492 lb 10/2/2007 United States
Primary
Secondary
Mucosal Inflammation Hospitalization 10/5/2007 Female 64 lb 10/9/2007 United States
Primary
Secondary
Wound Secretion Hospitalization 9/27/2007 Male 467 lb 10/8/2007 United States
Primary
Secondary
Depressed Level Of Consciousness 10/16/2007 Female 114 lb 10/22/2007 United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/17/2007 Female 187 lb 11/2/2007 Consumer United States
Primary
Concomitant
Wound Treatment Hospitalization 1/25/2005 41 Female 220 lb 11/14/2007 United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 5/12/2006 69 Male 174 lb 11/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nasopharyngitis 1/15/2007 Female 130 lb 12/11/2007 Physician United States
Primary
Concomitant
Liver Disorder Hospitalization 10/17/2007 Female 187 lb 12/12/2007 Consumer United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis 2/22/2007 Female 148 lb 12/13/2007 Physician United States
Primary
Concomitant
Gastritis 7/15/2007 Female 124 lb 12/13/2007 Physician United States
Primary
Concomitant
Drug Ineffective 6/1/2007 Female 214 lb 3/14/2008 United States
Primary
Concomitant
Viral Infection Other Serious 4/1/2007 Female 107 lb 3/24/2008 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 3/22/2006 Female 223 lb 4/25/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 2/14/2008 Male 220 lb 4/25/2008 Physician Switzerland
Primary
Concomitant
Duodenal Ulcer Hospitalization 9/23/2005 Female 4/25/2008 Physician United Kingdom
Primary
Secondary
Subileus Hospitalization 11/14/2007 Male 4/28/2008 Physician France
Primary
Secondary
Concomitant
Duodenal Ulcer Hospitalization 9/23/2005 Female 4/30/2008 Other Health Professional United States
Primary
Secondary
Oedema Peripheral Hospitalization 11/5/2007 74 Male 6/2/2008 France
Primary
Concomitant
Urosepsis Hospitalization 6/9/2006 Female 6/26/2008 Physician United States
Primary
Concomitant
Fatigue Hospitalization 2/14/2008 Male 220 lb 7/29/2008 Physician Switzerland
Primary
Concomitant
Transplant Rejection Hospitalization 10/30/1999 Male 175 lb 8/4/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/1/2006 Female 9/19/2008 Physician
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 10/1/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/1/2006 62 Female 10/13/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 12/24/2008 Physician United States
Primary
Secondary
Concomitant
Kaposi's Sarcoma Other Serious 11/1/2008 77 Male 12/29/2008 Physician Canada
Primary
Concomitant
Vomiting Life Threatening 11/24/2008 55 Male 123 lb 12/30/2008 Physician Ecuador
Primary
Concomitant
Kaposi's Sarcoma Other Serious 11/1/2008 77 Male 1/16/2009 Physician Canada
Primary
Concomitant
Renal Failure Other Serious Male 1/21/2009 Consumer United Kingdom
Primary
Secondary
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/20/2009 Physician United States
Primary
Concomitant
Neurotoxicity Other Serious 16 Male 2/25/2009
Primary
Secondary
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 3/3/2009 Physician United States
Primary
Secondary
Concomitant
No Therapeutic Response Hospitalization 2/6/2009 Female 41 lb 3/4/2009 United States
Primary
Secondary
Hypersensitivity 12/18/2008 Female 155 lb 3/14/2009
Primary
Concomitant
Pain In Extremity Other Serious 11/16/2008 Female 3/16/2009
Primary
Concomitant
Suicidal Ideation Hospitalization 2/19/2009 58 Male 171 lb 3/4/2009 Physician United States
Primary
Concomitant
No Therapeutic Response Hospitalization 2/6/2009 Female 41 lb 3/16/2009 United States
Primary
Secondary
Mucosal Inflammation Other Serious 3/20/2009 Physician Japan
Primary
Concomitant
Mucosal Inflammation Other Serious 3/20/2009 Physician Japan
Primary
Concomitant
Hepatotoxicity Other Serious 3/20/2009 Physician Japan
Primary
Concomitant
Cellulitis Hospitalization 3/14/2009 Female 3/24/2009 Physician United States
Primary
Concomitant
Neurotoxicity Hospitalization 16 Male 4/28/2009 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2008 Female 125 lb 5/12/2009 Physician United States
Primary
Concomitant
Osteonecrosis Disability 1/7/2009 80 Female 128 lb 5/14/2009 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Osteonecrosis Disability 1/7/2009 80 Female 128 lb 5/22/2009 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Urticaria Hospitalization 4/1/2005 Female 5/22/2009 Physician United States
Primary
Concomitant
Incorrect Dose Administered 3/17/2009 Female 180 lb 6/12/2009 Consumer United States
Primary
Concomitant
Herpes Zoster Hospitalization 6/2/2009 Female 192 lb 6/26/2009 Physician Canada
Primary
Concomitant
Herpes Zoster Hospitalization 6/2/2009 Female 192 lb 7/17/2009 Physician Canada
Primary
Concomitant
Skin Disorder Hospitalization 3/11/2009 Female 136 lb 8/11/2009 Other Health Professional Canada
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Lymphoma Other Serious 7/1/2009 66 Male 210 lb 8/17/2009 Other Health Professional Canada
Primary
Concomitant
Lymphoma Other Serious 7/1/2009 66 Male 210 lb 8/19/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 11/16/2008 Female 9/3/2009 Canada
Primary
Concomitant
Inappropriate Schedule Of Drug Administration 5/30/2009 Female 165 lb 9/18/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Systemic Lupus Erythematosus Rash Other Serious 51 Male 9/24/2009 Physician Italy
Primary
Secondary
Concomitant
Periorbital Cellulitis Hospitalization 6/11/2009 Female 192 lb 10/12/2009 Physician Canada
Primary
Concomitant
Pruritus Hospitalization 8/5/2009 Female 63 lb 11/3/2009 United States
Primary
Concomitant
Histoplasmosis Disseminated Hospitalization 10/3/2009 Male 199 lb 11/20/2009 Physician Canada
Primary
Concomitant
Thrombocytopenia Other Serious 3/7/2008 Female 170 lb 11/20/2009 Physician United States
Primary
Concomitant
Histoplasmosis Disseminated Hospitalization 10/3/2009 Male 199 lb 11/25/2009 Physician Canada
Primary
Concomitant
Wound Infection Other Serious 7/22/2009 Male 224 lb 12/3/2009 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 17 Male 12/9/2009
Primary
Secondary
Concomitant
Throat Tightness Other Serious 8/9/2004 Female 180 lb 12/29/2009 Consumer United States
Primary
Concomitant
Haematoma Hospitalization 12/28/2009 Female 149 lb 1/14/2010 Other Health Professional Canada
Primary
Concomitant
Wound Infection Other Serious 7/22/2009 Male 224 lb 2/5/2010 Consumer United States
Primary
Concomitant
Rib Fracture Hospitalization 12/28/2009 Female 149 lb 2/16/2010 Other Health Professional Canada
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 8/1/2005 Male 2/22/2010 Physician United States
Primary
Concomitant
Peripheral Sensory Neuropathy Disability 11/1/2009 32 Male 3/16/2010 Physician Switzerland
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 4/29/2010 United States
Primary
Secondary
Skin Toxicity Death 4/30/2010 Physician United Kingdom
Primary
Secondary
Paraesthesia Other Serious 13 Male 88 lb 5/3/2010 Other Health Professional Canada
Primary
Concomitant
Thrombosis Hospitalization Female 275 lb 6/8/2010 Consumer United States
Primary
Concomitant
Lymphadenitis Hospitalization 6/10/2010 44 Female 123 lb 6/17/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/5/2005 53 Male 174 lb 6/25/2010 Physician United States
Primary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 6/5/2005 53 Male 174 lb 7/1/2010 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 51 Female 8/3/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/31/2010 44 Female 250 lb 8/6/2010 United States
Primary
Secondary
Coronary Artery Occlusion Other Serious Male 140 lb 8/13/2010 Consumer Canada
Primary
Concomitant
Vomiting Other Serious 6/5/2005 53 Male 174 lb 8/18/2010 Physician United States
Primary
Concomitant
Coronary Artery Occlusion Other Serious Male 140 lb 8/20/2010 Physician Canada
Primary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 7/31/2010 62 Female 220 lb 9/8/2010 Consumer Canada
Primary
Concomitant
Lung Infection Hospitalization Male 128 lb 10/14/2010 United States
Primary
Concomitant
Pneumonia Hospitalization Male 128 lb 10/15/2010 United States
Primary
Concomitant
Lymphadenitis Hospitalization 6/10/2010 44 Female 123 lb 10/19/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization Male 128 lb 10/25/2010 United States
Primary
Concomitant
Neutropenic Sepsis Death 10/25/2010 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 10/25/2010 Other Health Professional United States
Primary
Secondary
Neuropathy Peripheral Other Serious 10/25/2010 Other Health Professional United States
Primary
Secondary
Neuropathy Peripheral Other Serious 10/25/2010 Other Health Professional United States
Primary
Secondary
Pneumonia Hospitalization Male 128 lb 10/27/2010 United States
Primary
Concomitant
Pneumonia Hospitalization 11/8/2010 70 Female 210 lb 11/23/2010 Physician Canada
Primary
Concomitant
Dyskinesia Hospitalization 11/17/2010 23 Female 12/23/2010 Other Health Professional France
Primary
Secondary
Concomitant
Headache Other Serious 9/1/2007 50 Male 194 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Injection Site Pain 8/6/2010 60 Female 1/29/2011 Consumer United States
Primary
Concomitant
Muscular Weakness 9/1/2010 60 Female 1/30/2011 Consumer United States
Primary
Concomitant
Arthralgia 10/30/2010 54 Female 1/30/2011 Consumer United States
Primary
Concomitant
Joint Swelling 7/1/2010 15 Male 156 lb 1/30/2011 Consumer United States
Primary
Concomitant
Decreased Appetite Other Serious 11/24/2010 72 Female 171 lb 2/3/2011 Physician United States
Primary
Concomitant
Haemorrhage Other Serious 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Burning Sensation Hospitalization Male 101 lb 3/3/2011 Other Health Professional Canada
Primary
Concomitant
Anxiety Death 3/8/2011 15 Female 144 lb 3/23/2011 Physician United States
Primary
Secondary
Peripheral Nerve Palsy Other Serious 3/28/2011 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Death 3/29/2011 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 3/29/2011 Physician Italy
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 3/31/2011 Physician Italy
Primary
Secondary
Concomitant
Asthenia Disability Female 4/29/2011 Lawyer United States
Primary
Concomitant
Infection Hospitalization 11/2/2010 18 Male 124 lb 5/13/2011 Physician United States
Primary
Secondary
Hypersensitivity Hospitalization 9/7/2010 74 Female 5/20/2011 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Death 3/8/2011 15 Female 144 lb 5/24/2011 Physician United States
Primary
Secondary
Drug Ineffective Other Serious 3/3/2011 65 Female 148 lb 6/21/2011 Other Health Professional Canada
Primary
Concomitant
Arthralgia Other Serious 8/1/2009 49 Female 187 lb 6/23/2011 Consumer Brazil
Primary
Secondary
Concomitant
Chills Hospitalization 6/1/2009 53 Female 213 lb 6/27/2011 Consumer United States
Primary
Secondary
Concomitant
Decubitus Ulcer Other Serious 62 Female 6/23/2011 Other Health Professional Germany
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 5/16/2011 66 Female 7/5/2011 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Hypotension Other Serious 3/8/2011 15 Female 144 lb 7/21/2011 Physician United States
Primary
Secondary

Drug Data