Leucovorin Calcium combined with Potassium Chloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Life Threatening 5/30/2005 Male 235 lb 1/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/28/2005 42 Female 205 lb 1/18/2006 Physician Canada
Primary
Secondary
Concomitant
Sepsis Syndrome Required Intervention 11/1/2005 23 Female 139 lb 12/5/2005 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/23/2005 69 Female 3/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Perforation Hospitalization 7/5/2005 68 Female 245 lb 6/5/2006 Physician Canada
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 7/18/2006 78 Female 8/25/2006 Pharmacist United States
Primary
Concomitant
Malignant Neoplasm Progression Death 56 Female 137 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 5/12/2006 69 Male 174 lb 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 2/18/2007 72 Male 192 lb 3/16/2007 Physician Germany
Primary
Secondary
Concomitant
Illusion Other Serious 3/6/2007 78 Female 128 lb 3/23/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 2/26/2007 Male 173 lb 4/11/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 7/18/2006 Female 5/17/2007 United States
Primary
Concomitant
Prostate Cancer Other Serious Male 217 lb 6/11/2007 Physician United States
Primary
Concomitant
Confusional State Other Serious 3/6/2007 Female 128 lb 7/5/2007 Consumer United States
Primary
Secondary
Concomitant
Trichiasis Other Serious 5/30/2007 Female 7/17/2007 Physician United Kingdom
Primary
Concomitant
Cerebral Ischaemia Hospitalization 7/1/2007 71 Male 8/16/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 8/14/2007 Female 165 lb 8/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/22/2007 77 Female 9/13/2007 United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 3/19/2007 65 Male 234 lb 11/8/2007 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 8/14/2007 Female 165 lb 11/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 8/14/2007 Female 165 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2000 Female 106 lb 12/6/2007 Physician United States
Primary
Concomitant
Abdominal Pain Hospitalization 5/12/2006 69 Male 174 lb 11/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/10/2007 Female 304 lb 12/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 2/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/26/2007 Female 2/6/2008 Physician Austria
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 2/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/26/2007 Female 3/17/2008 Physician Austria
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 1/1/2008 3/21/2008 Pharmacist France
Primary
Concomitant
Coronary Artery Stenosis Life Threatening 10/8/2007 Male 263 lb 3/25/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 4/21/2008 Male 4/24/2008 India
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/7/2008 Female 4/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 4/21/2008 Male 5/2/2008 India
Primary
Secondary
Concomitant
Oral Candidiasis Death 4/21/2008 Male 5/9/2008 India
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2000 Female 106 lb 6/11/2008 Physician United States
Primary
Concomitant
Death Death 4/21/2008 Male 7/3/2008 India
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/19/2008 72 Female 130 lb 7/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2000 Female 106 lb 7/10/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 7/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 1/1/2008 72 Female 130 lb 7/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 5/31/2008 50 Male 220 lb 8/1/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/14/2008 Male 8/4/2008 Physician United States
Primary
Concomitant
Swelling Face Hospitalization 4/1/2007 Female 8/6/2008 Physician United Kingdom
Primary
Concomitant
Swelling Face Hospitalization 4/1/2007 Female 8/18/2008 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 61 Female 199 lb 8/21/2008 United States
Primary
Concomitant
Pneumonia Hospitalization 7/14/2008 Male 9/4/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 9/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Hospitalization 8/31/2008 Male 170 lb 10/1/2008 Physician United States
Primary
Concomitant
Colitis Hospitalization 8/31/2008 Male 170 lb 10/8/2008 Physician United States
Primary
Concomitant
Hypokalaemia Hospitalization 10/14/2008 Female 110 lb 10/20/2008 United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 Female 138 lb 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 11/18/2008 53 Male 12/17/2008 Other Health Professional United States
Primary
Concomitant
Tenderness Hospitalization 12/10/2008 Female 140 lb 12/12/2008 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/7/2008 Female 12/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 10 Male 2/10/2009
Primary
Secondary
Concomitant
Pain Hospitalization 11/23/2007 54 Male 3/23/2009 Other Health Professional Israel
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/15/2007 Female 4/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 9/10/2008 4/23/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Temperature Intolerance Other Serious 3/1/2009 Female 128 lb 5/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Temperature Intolerance Other Serious 3/1/2009 Female 128 lb 5/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/26/2007 Female 6/8/2009 Physician Austria
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 2/12/2008 Female 8/13/2009 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/7/2008 69 Female 109 lb 1/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/8/2009 Female 138 lb 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Death 1/29/2010 Male 100 lb 2/16/2010 Consumer United States
Primary
Secondary
Concomitant
Disease Progression Death 1/29/2010 Male 100 lb 3/5/2010 Consumer United States
Primary
Secondary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Wheezing Hospitalization 11/20/2003 61 Female 140 lb 5/18/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/12/2009 72 Male 7/16/2010 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 4/12/2010 66 Female 264 lb 7/16/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 59 Female 132 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Hypophagia Death 1/1/2009 74 Female 133 lb 11/12/2010 Consumer United States
Primary
Concomitant
Hypophagia Death 1/1/2009 74 Female 133 lb 11/15/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 9/8/2010 50 Female 97 lb 11/30/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Dyskinesia Hospitalization 11/17/2010 23 Female 12/23/2010 Other Health Professional France
Primary
Secondary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/16/2010 14 Female 130 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/4/2011 16 Male 169 lb 5/11/2011 Physician United States
Primary
Concomitant
Decreased Appetite Hospitalization 7/1/2008 73 Female 5/24/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/8/2011 42 Male 161 lb 5/26/2011 Physician Austria
Primary
Secondary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 6/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/12/2011 11 Female 6/9/2011 Physician United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 2/8/2011 42 Male 161 lb 6/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Primary Atypical Hospitalization 5/8/2011 42 Male 161 lb 6/27/2011 Physician Austria
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Death 4/18/2011 73 Female 207 lb 6/27/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Primary Atypical Hospitalization 5/8/2011 42 Male 161 lb 7/6/2011 Physician Austria
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/1/2010 40 Male 126 lb 7/6/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Primary Atypical Hospitalization 5/8/2011 42 Male 161 lb 7/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dysstasia Other Serious 10/1/2006 58 Male 145 lb 8/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/5/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 8/8/2011 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 7/25/2011 67 Male 182 lb 8/28/2011 Physician United States
Primary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/30/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 9/2/2011 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 8/27/2009 60 Female 172 lb 9/13/2011 Physician Spain
Primary
Secondary
Concomitant
Enterocolitis Hospitalization Female 9/26/2011 Physician United States
Primary
Secondary
Concomitant
Enterocolitis Hospitalization Female 9/28/2011 Physician United States
Primary
Secondary
Concomitant
Colon Cancer Other Serious 1/2/2008 34 Female 10/17/2011 Consumer United States
Primary
Concomitant
Neoplasm Malignant Hospitalization 1/2/2008 34 Female 10/24/2011 Consumer United States
Primary
Concomitant
Enterocolitis Hospitalization Female 10/26/2011 Physician United States
Primary
Secondary
Concomitant
Drug Dose Omission Hospitalization 10/1/2010 54 Female 11/7/2011 Physician United States
Primary
Concomitant
Infection Hospitalization 10/1/2010 54 Female 11/9/2011 Physician United States
Primary
Concomitant
Death Hospitalization 11/28/2011 36 Male 204 lb 11/30/2011 Physician United States
Primary
Concomitant
Death Death 11/28/2011 36 Male 204 lb 12/3/2011 Physician United States
Primary
Concomitant
Hemiparesis Hospitalization 11/17/2007 71 Male 122 lb 12/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyskinesia Hospitalization 1/2/2008 34 Female 12/14/2011 Consumer United States
Primary
Concomitant
Leukopenia Other Serious 2/26/2007 68 Male 173 lb 12/20/2011 Consumer United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 2/26/2007 68 Male 173 lb 12/27/2011 Consumer United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 2/26/2007 68 Male 173 lb 12/29/2011 Physician United States
Primary
Secondary
Concomitant
Breast Cancer Metastatic Hospitalization 1/2/2008 34 Female 1/1/2012 Lawyer United States
Primary
Concomitant
Radicular Cyst Death 12/1/2007 68 Male 1/6/2012 Physician United States
Primary
Concomitant
Lymphadenopathy Other Serious 12/1/2007 68 Male 1/9/2012 Physician United States
Primary
Concomitant
Colitis Ulcerative Life Threatening 1/1/2011 28 Female 1/10/2012 Physician France
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious Female 160 lb 1/4/2012 Lawyer United States
Primary
Concomitant
Staphylococcal Sepsis Death 12/1/2007 68 Male 1/13/2012 Physician United States
Primary
Concomitant
Cardiac Arrest Life Threatening 11/28/2011 36 Male 204 lb 1/23/2012 Physician United States
Primary
Concomitant
Colon Cancer Metastatic Hospitalization 1/2/2008 34 Female 1/23/2012 Consumer United States
Primary
Concomitant
Gout Hospitalization 12/1/2007 68 Male 1/24/2012 Physician United States
Primary
Concomitant
Enterocolitis Hospitalization Female 1/24/2012 Physician United States
Primary
Secondary
Concomitant
Pyrexia 10/1/2011 77 Female 148 lb 1/29/2012 Consumer United States
Primary
Secondary
Concomitant
Melaena Other Serious 12/1/2011 64 Female 1/31/2012 Consumer Italy
Primary
Concomitant
Injection Site Haematoma Female 1/29/2012 Consumer United States
Primary
Concomitant
Pain 6/1/2011 74 Male 1/28/2012 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 12/1/2007 68 Male 2/6/2012 Lawyer United States
Primary
Concomitant
Anaemia Other Serious 12/1/2011 64 Female 2/7/2012 Physician Italy
Primary
Concomitant
Anaemia Other Serious 12/1/2011 64 Female 2/13/2012 Physician Italy
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 1/24/2012 77 Male 2/21/2012 Other Health Professional France
Primary
Secondary
Concomitant
Overdose Other Serious 1/24/2012 77 Male 2/28/2012 Other Health Professional France
Primary
Secondary
Concomitant
Lymphoedema Hospitalization 1/3/2012 63 Female 108 lb 3/8/2012 Physician Finland
Primary
Secondary
Concomitant
Fall Other Serious 12/1/2007 68 Male 3/8/2012 Physician United States
Primary
Concomitant
Hypocoagulable State Hospitalization 12/27/2009 78 Female 3/29/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 16 Female 106 lb 4/2/2012 Pharmacist Canada
Primary
Concomitant
Dyspnoea Hospitalization Male 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 11/28/2011 36 Male 204 lb 4/17/2012 Physician United States
Primary
Concomitant
Hypocoagulable State Hospitalization 12/27/2009 78 Female 4/17/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Malaise Hospitalization 4/10/2012 59 Female 230 lb 4/11/2012 United States
Primary
Secondary
Concomitant
Electrocardiogram Qrs Complex Prolonged Hospitalization 12/1/2007 68 Male 4/24/2012 Lawyer United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 3/9/2012 59 Female 150 lb 4/27/2012 Other Health Professional France
Primary
Concomitant
Coronary Artery Disease Death Female 140 lb 5/7/2012 Consumer United States
Primary
Secondary
Concomitant
Serum Ferritin Increased Hospitalization 4/1/2011 55 Female 5/14/2012 Consumer United States
Primary
Concomitant
Anaemia Hospitalization 12/1/2009 65 Female 5/15/2012 Consumer Italy
Primary
Concomitant
Dehydration Hospitalization 9/8/2010 50 Female 97 lb 5/22/2012 Consumer Germany
Primary
Secondary
Concomitant
Migraine Hospitalization 1/2/2008 34 Female 5/29/2012 Consumer United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 1/1/2012 59 Female 150 lb 5/31/2012 Other Health Professional France
Primary
Concomitant
Interacting
Haemorrhage Intracranial Hospitalization 4/1/2012 74 Male 183 lb 6/14/2012 Physician United States
Primary
Concomitant
Renal Failure Chronic Other Serious 4/1/2011 83 Female 6/14/2012 Physician United States
Primary
Concomitant

Drug Data