Leucovorin Calcium combined with Panitumumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Coronary Artery Disease Other Serious 62 Male 8/21/2006 Physician United States
Primary
Secondary
Mitral Valve Incompetence Other Serious 8/8/2006 62 Male 154 lb 9/1/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 7/1/2005 Male 10/30/2006 Physician United States
Primary
Secondary
Concomitant
Skin Infection Hospitalization 10/4/2006 Female 10/30/2006 Physician
Primary
Concomitant
Malnutrition Hospitalization 10/10/2006 Female 10/30/2006 Physician United States
Primary
Secondary
Syncope Hospitalization 10/28/2006 Male 11/8/2006 Physician Canada
Primary
Concomitant
Malnutrition Hospitalization 10/10/2006 Female 11/8/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2006 Female 11/9/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 7/1/2005 Male 11/13/2006 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 11/13/2006 Physician United States
Primary
Secondary
Small Intestinal Obstruction Hospitalization 5/26/2006 Female 167 lb 11/15/2006 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 5/12/2006 Male 11/16/2006 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/1/2006 Female 11/16/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/25/2006 Male 11/17/2006 Physician Australia
Primary
Secondary
White Blood Cell Count Increased Hospitalization 9/29/2006 Male 11/20/2006 Physician Australia
Primary
Concomitant
Large Intestine Perforation Hospitalization 1/23/2006 Male 11/20/2006 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 11/11/2006 Female 11/22/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/4/2006 Male 11/22/2006 Physician United States
Primary
Concomitant
Rash Hospitalization 10/27/2006 Female 11/22/2006 Physician Australia
Primary
Secondary
Concomitant
Dyspnoea Death 5/21/2006 Female 11/22/2006 Physician United States
Primary
Concomitant
Gait Disturbance Hospitalization 11/13/2006 Male 11/22/2006 Physician Australia
Primary
Concomitant
Hypotension Hospitalization 11/7/2006 Male 11/22/2006 Physician Australia
Primary
Secondary
Concomitant
Abscess Hospitalization 11/11/2006 Male 11/28/2006 Physician United Kingdom
Primary
Concomitant
Abscess Hospitalization 11/11/2006 Male 12/4/2006 Physician United Kingdom
Primary
Concomitant
Hypotension Hospitalization 11/11/2006 Female 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 8/9/2006 Male 12/6/2006 Physician Australia
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 11/13/2006 Male 12/6/2006 Physician Australia
Primary
Concomitant
Hypomagnesaemia Life Threatening 9/26/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Vena Cava Thrombosis Other Serious 11/29/2006 Male 12/11/2006 Physician Australia
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/3/2006 Male 12/11/2006 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 10/10/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 11/11/2006 Male 12/11/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/26/2006 Female 12/11/2006 Physician United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 11/13/2006 Male 12/15/2006 Physician Australia
Primary
Concomitant
Urinary Retention Hospitalization 6/7/2005 Male 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Rash Disability 6/5/2006 Female 12/20/2006 Physician United States
Primary
Secondary
Concomitant
Hypomagnesaemia Life Threatening 9/26/2006 Female 12/20/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 12/7/2006 Female 12/27/2006 Physician United States
Primary
Secondary
Concomitant
Ulcer Hospitalization 10/31/2005 Male 12/27/2006 Physician United States
Primary
Concomitant
Rash Pustular Disability 6/5/2006 Female 12/27/2006 Physician United States
Primary
Secondary
Concomitant
Colitis Ulcerative Hospitalization 11/7/2005 Female 1/2/2007 Physician United States
Primary
Concomitant
Ulcer Hospitalization 10/31/2005 Male 1/2/2007 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 12/27/2006 Male 1/16/2007 Physician Australia
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 12/22/2006 Female 1/22/2007 Physician Australia
Primary
Secondary
Fatigue Hospitalization 11/27/2006 Male 1/22/2007 Physician Poland
Primary
Concomitant
Chest Pain Hospitalization 1/12/2007 Male 1/24/2007 Physician Ireland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/8/2007 Female 1/29/2007 Physician Poland
Primary
Concomitant
Fatigue Hospitalization 11/27/2006 Male 1/30/2007 Physician Poland
Primary
Concomitant
Fatigue Hospitalization 11/27/2006 Male 1/31/2007 Physician Poland
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 11/27/2006 Male 2/9/2007 Physician Poland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/8/2007 Female 2/12/2007 Physician Poland
Primary
Concomitant
Pyelonephritis Hospitalization 12/22/2006 Female 2/19/2007 Physician Australia
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/27/2006 Male 2/19/2007 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/8/2007 Female 2/23/2007 Physician Poland
Primary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 139 lb 2/26/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2/9/2007 Female 3/1/2007 Physician United States
Primary
Concomitant
Septic Shock Life Threatening 3/31/2006 Male 3/1/2007 Physician United States
Primary
Concomitant
Skin Infection Hospitalization 2/14/2007 Female 3/2/2007 Physician Chile
Primary
Concomitant
Atrial Fibrillation Other Serious 2/17/2007 Male 3/5/2007 Physician Canada
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/26/2007 Male 3/9/2007 Physician Australia
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 2/19/2007 Female 3/9/2007 Physician Australia
Primary
Secondary
Diarrhoea Hospitalization 12/27/2006 Male 3/12/2007 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/8/2007 Female 3/13/2007 Physician Poland
Primary
Concomitant
Diarrhoea Other Serious 2/18/2007 Female 3/15/2007 Physician Chile
Primary
Concomitant
Skin Infection Hospitalization 2/14/2007 Female 3/19/2007 Physician Chile
Primary
Concomitant
Intestinal Obstruction Hospitalization 3/1/2007 Female 3/20/2007 Physician
Primary
Concomitant
Febrile Neutropenia Hospitalization 3/7/2007 Male 160 lb 3/23/2007 Physician United States
Primary
Secondary
Sepsis Hospitalization 3/10/2007 Male 3/23/2007 Physician Australia
Primary
Secondary
Skin Infection Hospitalization 10/4/2006 Female 3/26/2007 Physician
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 2/19/2007 Female 3/28/2007 Physician Australia
Primary
Secondary
Hypokalaemia Hospitalization 3/1/2007 Female 136 lb 4/2/2007 Physician United States
Primary
Concomitant
Rash Hospitalization 3/17/2007 Male 4/2/2007 Physician Australia
Primary
Secondary
Concomitant
Skin Infection Hospitalization 2/14/2007 Female 4/2/2007 Physician Chile
Primary
Concomitant
Skin Infection Hospitalization 10/4/2006 Female 4/2/2007 Physician
Primary
Concomitant
Nausea Hospitalization 3/17/2007 Female 4/3/2007 Physician United States
Primary
Concomitant
Oral Soft Tissue Disorder Hospitalization 3/7/2007 Male 160 lb 4/5/2007 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 139 lb 4/5/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 3/24/2007 Male 4/11/2007 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 3/29/2007 Male 4/13/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 3/10/2007 Male 4/17/2007 Physician Australia
Primary
Secondary
Intestinal Obstruction Hospitalization 3/1/2007 Female 4/17/2007 Physician United States
Primary
Concomitant
Palpitations Other Serious 7/12/2006 Male 4/17/2007 Physician
Primary
Concomitant
Mucosal Inflammation Hospitalization 3/29/2007 Male 4/20/2007 Physician United States
Primary
Concomitant
Syncope Hospitalization 10/28/2006 Male 4/20/2007 Physician Canada
Primary
Concomitant
Septic Shock Hospitalization 3/31/2006 Male 4/20/2007 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 4/8/2007 Male 4/20/2007 Physician Hungary
Primary
Concomitant
Pancytopenia Hospitalization 3/24/2007 Male 164 lb 4/20/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2/9/2007 Female 4/24/2007 Physician United States
Primary
Secondary
Pericardial Effusion Hospitalization 8/6/2006 Male 4/24/2007 Physician United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 8/6/2006 Male 4/24/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Infection Hospitalization 4/14/2007 Male 4/26/2007 Physician Poland
Primary
Concomitant
Rash Hospitalization 3/17/2007 Male 4/26/2007 Physician Australia
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 2/19/2007 Female 4/27/2007 Physician Australia
Primary
Secondary
Female Genital Tract Fistula Other Serious 8/30/2005 Female 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Dermatitis Infected Hospitalization 8/23/2006 Male 5/4/2007 Physician Australia
Primary
Concomitant
Thrombosis Hospitalization 4/2/2007 Male 5/4/2007 Physician Poland
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 4/8/2007 Male 5/4/2007 Physician Hungary
Primary
Concomitant
Tooth Infection Hospitalization 4/14/2007 Male 5/7/2007 Physician Poland
Primary
Concomitant
Atrial Fibrillation Hospitalization 4/26/2007 Female 5/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Asthenia Hospitalization 4/12/2007 Male 5/7/2007 Physician Romania
Primary
Concomitant
Diarrhoea Other Serious 4/23/2007 Female 5/8/2007 Physician Argentina
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/23/2006 Male 5/11/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 3/31/2006 Male 5/14/2007 Physician United States
Primary
Concomitant
Jugular Vein Thrombosis Hospitalization 8/13/2006 Female 5/14/2007 Physician United States
Primary
Secondary
Atrial Fibrillation Other Serious 2/17/2007 Male 5/14/2007 Physician Canada
Primary
Secondary
Concomitant
Syncope Hospitalization 10/28/2006 Male 5/14/2007 Physician Canada
Primary
Concomitant
Pancytopenia Hospitalization 3/24/2007 Male 164 lb 5/14/2007 Physician United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 4/26/2007 Female 5/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Lethargy Hospitalization 5/4/2007 Male 5/17/2007 Physician Australia
Primary
Concomitant
Platelet Count Decreased Hospitalization 3/29/2007 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/23/2007 Female 5/17/2007 Physician Argentina
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 4/8/2007 Male 5/18/2007 Physician Hungary
Primary
Concomitant
Rash Disability 6/5/2006 Female 5/21/2007 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/7/2007 Male 160 lb 5/21/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/10/2007 Male 5/21/2007 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 5/14/2007 Male 5/24/2007 Physician Italy
Primary
Concomitant
Tooth Infection Hospitalization 4/14/2007 Male 5/24/2007 Physician Poland
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/14/2007 Female 5/24/2007 Physician Italy
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 8/9/2006 Male 5/25/2007 Physician Australia
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 4/8/2007 Male 5/25/2007 Physician Hungary
Primary
Concomitant
Vomiting Other Serious 5/8/2007 Male 5/29/2007 Physician Australia
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 139 lb 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 5/1/2007 Female 5/31/2007 Physician United Kingdom
Primary
Concomitant
Swelling Face Hospitalization 4/1/2007 Female 5/31/2007 Physician United Kingdom
Primary
Concomitant
Pseudomonal Sepsis Hospitalization 4/23/2007 Female 6/1/2007 Physician Argentina
Primary
Secondary
Concomitant
Vomiting Other Serious 5/8/2007 Male 6/4/2007 Physician Australia
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/5/2007 Male 6/4/2007 Physician Ireland
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/30/2007 Male 6/4/2007 Physician Argentina
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/4/2007 Male 6/4/2007 Physician Australia
Primary
Concomitant
Asthenia Hospitalization 4/12/2007 Male 6/4/2007 Physician Romania
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/4/2007 Male 6/8/2007 Physician Australia
Primary
Concomitant
Febrile Neutropenia Hospitalization 3/30/2007 Male 6/8/2007 Physician Argentina
Primary
Secondary
Concomitant
Hair Growth Abnormal Other Serious 5/30/2007 Female 6/12/2007 Physician United Kingdom
Primary
Concomitant
Thrombosis Hospitalization 4/2/2007 Male 6/12/2007 Physician Poland
Primary
Concomitant
Ileus Hospitalization 3/1/2007 Male 6/13/2007 Physician Austria
Primary
Secondary
Concomitant
Impetigo Hospitalization 6/4/2007 Male 6/13/2007 Physician Hungary
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 5/14/2007 Male 6/15/2007 Physician Australia
Primary
Concomitant
Dehydration Hospitalization 11/22/2005 Male 6/15/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 5/14/2007 Male 6/15/2007 Physician Italy
Primary
Concomitant
Venous Thrombosis Other Serious 5/31/2007 Male 6/15/2007 Physician Argentina
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/14/2007 Female 6/15/2007 Physician Italy
Primary
Concomitant
Pyrexia Hospitalization 6/3/2007 Female 6/18/2007 Physician Spain
Primary
Secondary
Large Intestine Perforation Life Threatening 6/6/2007 Male 6/19/2007 Physician Chile
Primary
Concomitant
Sepsis Hospitalization 6/1/2007 Female 6/19/2007 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 3/30/2007 Male 6/20/2007 Physician Argentina
Primary
Secondary
Concomitant
Hyperhidrosis Hospitalization 6/14/2007 Male 6/21/2007 Physician Australia
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 5/1/2007 Female 6/22/2007 Physician United Kingdom
Primary
Concomitant
Hair Growth Abnormal Other Serious 5/30/2007 Female 6/25/2007 Physician United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 6/8/2007 Male 6/25/2007 Physician Chile
Primary
Concomitant
Vaginal Pain Hospitalization 5/7/2007 Female 6/25/2007 Physician Belgium
Primary
Concomitant

Drug Data