Leucovorin Calcium combined with Oxycontin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Hospitalization 6/30/2005 62 Male 3/15/2006 Physician United States
Primary
Secondary
Vomiting Hospitalization 8/8/2005 55 Male 181 lb 3/30/2006 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 Female 169 lb 5/3/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 57 Female 5/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 65 Female 169 lb 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/28/2005 62 Female 6/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/28/2006 Female 169 lb 7/3/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2006 65 Female 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stent Placement Life Threatening 5/1/2006 65 Female 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/1/2006 65 Female 7/20/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/19/2006 56 Male 223 lb 7/27/2006 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/2/2006 Male 150 lb 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/4/2006 Male 11/22/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 8/14/2006 Male 160 lb 12/4/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 3/24/2005 70 Male 8/29/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 153 lb 1/19/2007 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 57 Female 1/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 153 lb 2/20/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/9/2007 Male 158 lb 2/22/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/9/2007 Male 158 lb 3/2/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/9/2007 Male 158 lb 3/13/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/9/2007 Male 158 lb 3/16/2007 Other Health Professional
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/9/2007 Male 158 lb 3/30/2007 Other Health Professional
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2005 48 Male 4/2/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 12/6/2006 Male 4/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/2/2007 Male 149 lb 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 5/27/2007 Male 106 lb 7/17/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 10/8/2007 75 Female 10/9/2007 Physician United States
Primary
Concomitant
Renal Infarct Hospitalization 9/25/2007 Male 11/14/2007 Physician Australia
Primary
Concomitant
Pneumonia Hospitalization 10/8/2007 75 Female 11/8/2007 Physician United States
Primary
Concomitant
Renal Infarct Hospitalization 9/25/2007 Male 11/19/2007 Physician Australia
Primary
Concomitant
Sepsis Hospitalization 10/26/2007 Male 169 lb 11/21/2007 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/26/2007 Male 169 lb 11/27/2007 United States
Primary
Secondary
Concomitant
Renal Infarct Hospitalization 9/25/2007 Male 11/29/2007 Physician Australia
Primary
Concomitant
Renal Infarct Hospitalization 9/25/2007 Male 12/5/2007 Physician Australia
Primary
Concomitant
Perirectal Abscess Hospitalization 11/13/2007 Male 12/11/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 10/26/2007 Male 162 lb 12/17/2007 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/8/2007 75 Female 12/17/2007 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 2/24/2005 Male 177 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2/24/2005 Male 177 lb 2/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Haematemesis Hospitalization 1/13/2008 Male 2/6/2008 Physician France
Primary
Concomitant
Pneumonia Hospitalization 2/13/2008 57 Male 2/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Melaena Hospitalization 1/13/2008 Male 2/27/2008 Physician France
Primary
Secondary
Concomitant
Melaena Hospitalization 1/13/2008 Male 3/12/2008 Physician France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/30/2007 75 Female 3/4/2008 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 2/13/2008 57 Male 3/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Musculoskeletal Pain Hospitalization 9/4/2007 Male 3/24/2008 Physician Australia
Primary
Concomitant
Stomatitis Hospitalization 9/2/2007 Female 6/20/2008 Physician Japan
Primary
Secondary
Concomitant
Nausea Life Threatening 6/25/2008 Female 118 lb 7/28/2008 Physician Japan
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 5/26/2008 28 Male 121 lb 8/25/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/11/2008 Male 8/29/2008 Physician United Kingdom
Primary
Concomitant
Sepsis Life Threatening 7/11/2008 Male 10/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/11/2008 Male 10/22/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/14/2008 Male 11/10/2008 Japan
Primary
Secondary
Concomitant
Perinephric Collection Hospitalization 9/25/2007 Male 11/19/2008 Physician Australia
Primary
Concomitant
Sepsis Other Serious 7/11/2008 Male 12/1/2008 Japan
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 11/17/2008 Male 12/15/2008 Physician United States
Primary
Concomitant
Hepatitis Other Serious 6/11/2008 Female 135 lb 12/19/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 11/17/2008 Male 12/24/2008 Physician United States
Primary
Concomitant
Road Traffic Accident Other Serious 11/17/2008 Male 12/31/2008 Physician United States
Primary
Concomitant
Road Traffic Accident Other Serious 11/17/2008 Male 1/6/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 11/17/2008 Female 132 lb 2/19/2009 Physician United States
Primary
Secondary
Concomitant
Road Traffic Accident Hospitalization 11/17/2008 Male 2/24/2009 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 10/26/2007 Male 162 lb 3/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Anorectal Operation Hospitalization 4/10/2009 Male 166 lb 4/23/2009 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Perforation Hospitalization 11/5/2008 Male 5/5/2009 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 4/10/2009 Male 166 lb 5/12/2009 Physician United States
Primary
Secondary
Concomitant
Central Line Infection Hospitalization 8/12/2009 Male 9/4/2009 Physician United Kingdom
Primary
Concomitant
Paraesthesia Other Serious 9/2/2009 Female 148 lb 9/14/2009 Pharmacist Australia
Primary
Concomitant
Delirium Hospitalization 2/20/2009 Male 9/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Delirium Hospitalization 2/20/2009 Male 9/23/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Paraesthesia Other Serious 9/2/2009 Female 148 lb 9/28/2009 Pharmacist Australia
Primary
Concomitant
Central Line Infection Hospitalization 8/12/2009 Male 9/28/2009 Physician United Kingdom
Primary
Concomitant
Ventricular Fibrillation Death 7/23/2009 Female 174 lb 10/7/2009 Consumer Australia
Primary
Secondary
Concomitant
Myocardial Infarction Death 7/23/2009 Female 10/9/2009 Consumer Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/7/2009 Female 126 lb 10/15/2009 United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Hospitalization 10/20/2009 Female 126 lb 11/11/2009 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 10/13/2009 72 Male 128 lb 11/25/2009 Physician Israel
Primary
Secondary
Concomitant
Paraesthesia Other Serious 9/2/2009 Female 148 lb 12/4/2009 Pharmacist Australia
Primary
Concomitant
Pyrexia Other Serious 10/13/2009 72 Male 128 lb 12/11/2009 Physician Israel
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 10/20/2009 71 Female 126 lb 12/16/2009 Physician Germany
Primary
Concomitant
Paraesthesia Other Serious 9/2/2009 Female 148 lb 12/17/2009 Pharmacist Australia
Primary
Concomitant
Pyrexia Other Serious 10/13/2009 72 Male 128 lb 12/18/2009 Physician Israel
Primary
Secondary
Concomitant
Vomiting Other Serious 9/20/2007 47 Female 141 lb 4/19/2010 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 10/20/2009 71 Female 126 lb 4/29/2010 Physician Germany
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 7/13/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Malaise Hospitalization 6/25/2010 65 Female 8/4/2010 Physician Japan
Primary
Secondary
Concomitant
Ileal Perforation Hospitalization 12/30/2009 49 Female 8/10/2010 Physician Spain
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2009 62 Male 148 lb 8/11/2010 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 6/4/2010 65 Female 8/19/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/8/2008 56 Male 8/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/8/2008 56 Male 8/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/1/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Small Intestinal Perforation Other Serious 5/6/2010 62 Male 141 lb 9/8/2010 Physician Japan
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Malaise Hospitalization 6/4/2010 65 Female 9/21/2010 Physician Japan
Primary
Secondary
Concomitant
Small Intestine Ulcer Other Serious 7/28/2010 55 Male 115 lb 9/24/2010 Physician Japan
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/28/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 10/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/1/2010 69 Female 1/13/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 10/20/2010 69 Female 95 lb 1/14/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 2/22/2010 72 Male 123 lb 1/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Abdominal Infection Other Serious 1/1/2010 69 Female 1/20/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 10/20/2010 69 Female 95 lb 1/24/2011 Physician Japan
Primary
Secondary
Concomitant
Perirectal Abscess 2/15/2011 34 Male 167 lb 2/15/2011 United States
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 10/20/2010 69 Female 95 lb 3/28/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Infection Hospitalization 1/1/2010 69 Female 3/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 12/10/2010 77 Female 126 lb 5/16/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Death 12/10/2010 77 Female 126 lb 5/16/2011 Physician Japan
Primary
Secondary
Concomitant
Metastases To Lung Death 10/3/2009 72 Female 127 lb 5/10/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Febrile Neutropenia Death 4/26/2010 60 Male 163 lb 5/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/11/2010 65 Female 101 lb 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Colorectal Cancer Death 10/18/2010 75 Female 115 lb 5/25/2011 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Death 10/18/2010 58 Male 165 lb 5/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Ischaemia Disability 8/29/2010 56 Female 108 lb 5/27/2011 Physician France
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 5/11/2011 61 Male 152 lb 5/29/2011 Physician Germany
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 11/24/2010 62 Female 95 lb 6/1/2011 Physician Japan
Primary
Concomitant
Pain Other Serious 8/18/2010 66 Male 159 lb 6/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Small Intestine Ulcer Hospitalization 75 Male 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 8/29/2010 56 Female 6/9/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Dermatitis Death 7/29/2010 65 Male 104 lb 6/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Colorectal Cancer Other Serious 12/7/2010 55 Female 104 lb 6/29/2011 Physician Japan
Primary
Secondary
Concomitant
Headache Hospitalization 6/20/2011 55 Male 6/29/2011 Physician Japan
Primary
Concomitant
Headache Hospitalization 6/20/2011 55 Male 6/30/2011 Physician Japan
Primary
Concomitant
Neuralgia Hospitalization 6/20/2011 55 Male 6/30/2011 Physician Japan
Primary
Concomitant
Colorectal Cancer Other Serious 8/18/2010 66 Male 159 lb 7/1/2011 Physician Japan
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 11/24/2010 62 Female 95 lb 7/18/2011 Physician Japan
Primary
Concomitant
Hyperhidrosis Hospitalization 5/24/2011 55 Male 128 lb 7/18/2011 Pharmacist Japan
Primary
Concomitant
Decreased Appetite Hospitalization 6/20/2011 51 Male 192 lb 7/20/2011 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Death 10/10/2010 61 Female 121 lb 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 6/20/2011 57 Female 8/1/2011 Consumer United States
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious 9/15/2010 69 Female 95 lb 8/16/2011 Physician Japan
Primary
Secondary
Concomitant
Duodenal Ulcer Other Serious 12/18/2009 56 Female 117 lb 8/17/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 7/29/2010 65 Male 104 lb 8/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Nausea Death 10/10/2010 61 Female 121 lb 8/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Colorectal Cancer Death 12/7/2010 55 Female 104 lb 8/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Feeling Hot Hospitalization 7/12/2011 63 Male 132 lb 9/6/2011 Consumer Japan
Primary
Concomitant
Colon Cancer Other Serious 1/2/2008 34 Female 10/17/2011 Consumer United States
Primary
Concomitant
Neoplasm Malignant Hospitalization 1/2/2008 34 Female 10/24/2011 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/29/2010 56 Female 108 lb 11/7/2011 France
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/22/2011 58 Female 265 lb 12/9/2011 Other Health Professional Australia
Primary
Concomitant
Dyskinesia Hospitalization 1/2/2008 34 Female 12/14/2011 Consumer United States
Primary
Concomitant
Breast Cancer Metastatic Hospitalization 1/2/2008 34 Female 1/1/2012 Lawyer United States
Primary
Concomitant
Radicular Cyst Death 12/1/2007 68 Male 1/6/2012 Physician United States
Primary
Concomitant
Lymphadenopathy Other Serious 12/1/2007 68 Male 1/9/2012 Physician United States
Primary
Concomitant
Staphylococcal Sepsis Death 12/1/2007 68 Male 1/13/2012 Physician United States
Primary
Concomitant
Colon Cancer Metastatic Hospitalization 1/2/2008 34 Female 1/23/2012 Consumer United States
Primary
Concomitant
Gout Hospitalization 12/1/2007 68 Male 1/24/2012 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Bacterial Female 1/28/2012 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 12/1/2007 68 Male 2/6/2012 Lawyer United States
Primary
Concomitant

Drug Data