Leucovorin Calcium combined with Oxaliplatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Life Threatening 5/30/2005 Male 235 lb 1/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 5/25/2005 69 Male 132 lb 1/4/2006 Physician Switzerland
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Required Intervention 12/29/2005 Male 203 lb 1/5/2006 United States
Primary
Secondary
Oesophagitis Life Threatening 11/5/2005 Male 205 lb 1/31/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pneumatosis Hospitalization 3/10/2005 Male 162 lb 1/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Polyuria Other Serious 10/7/2005 71 Male 132 lb 2/15/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Throat Tightness Required Intervention 1/31/2006 Female 112 lb 2/9/2006 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 10/11/2005 63 Male 2/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 2/17/2006 46 Female 129 lb 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 10/10/2005 70 Male 181 lb 2/17/2006 Physician France
Primary
Secondary
Concomitant
Vocal Cord Paralysis Disability 7/1/2005 52 Female 166 lb 2/22/2006 Physician United States
Primary
Concomitant
Central Line Infection Hospitalization 8/19/2004 61 Male 154 lb 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2005 3/3/2006 Physician United States
Primary
Secondary
Large Intestine Perforation Hospitalization 2/25/2006 70 Male 2/28/2006 Pharmacist United States
Primary
Secondary
Staphylococcal Infection Hospitalization 1/17/2005 73 Male 141 lb 3/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 2/17/2006 Male 159 lb 3/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/29/2006 52 Male 3/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 11/6/2005 Male 3/9/2006 Physician United States
Primary
Secondary
Renal Failure Acute Hospitalization 1/1/2006 73 Male 141 lb 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/15/2006 Male 3/10/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 8/6/2005 Male 3/14/2006 Physician Germany
Primary
Secondary
Concomitant
Arrhythmia Hospitalization 2/28/2006 Male 3/15/2006 Physician Canada
Primary
Secondary
Syncope Hospitalization 6/30/2005 62 Male 3/15/2006 Physician United States
Primary
Secondary
Colitis Ulcerative Life Threatening 11/12/2005 Female 3/16/2006 Physician France
Primary
Secondary
Tremor Life Threatening 2/14/2006 Male 3/16/2006 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/15/2006 Male 3/21/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombosis Hospitalization 12/22/2005 61 Female 3/21/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Death 3/28/2006 Male 164 lb 4/10/2006 United States
Primary
Secondary
Vocal Cord Paralysis Other Serious Unknown 4/10/2006 Pharmacist United States
Primary
Concomitant
Vasculitis Hospitalization 74 Male 5/11/2006 Other Health Professional Ireland
Primary
Concomitant
Impaired Healing Female 3/1/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred 70 Male 3/1/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 8/11/2005 Male 132 lb 6/6/2006 Other Health Professional Japan
Primary
Secondary
Metastases To Bone Other Serious 11/12/2005 Male 119 lb 6/6/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/31/2005 Male 6/6/2006 Consumer United States
Primary
Secondary
Vasculitis Hospitalization 74 Male 5/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 8/3/2005 Male 121 lb 6/6/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 5/23/2006 75 Male 5/31/2006 Other Health Professional United States
Primary
Concomitant
Therapy Non-responder Death 3/31/2006 76 Male 126 lb 6/13/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Peritonitis Other Serious 6/20/2005 Female 84 lb 6/14/2006 Other Health Professional Japan
Primary
Secondary
Pneumonitis Other Serious Female 6/15/2006 Physician Germany
Primary
Concomitant
Shock Life Threatening 2/5/2006 Male 139 lb 6/15/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Other Serious 6/2/2006 61 Male 6/20/2006 Other Health Professional Germany
Primary
Secondary
Splenomegaly Other Serious Male 6/13/2006 Physician France
Primary
Concomitant
Pneumonitis Death Female 6/26/2006 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 4/28/2005 62 Female 6/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/2/2006 Male 6/28/2006 Physician France
Primary
Secondary
Concomitant
Pneumothorax Other Serious 5/4/2006 Male 6/29/2006 Physician Germany
Primary
Concomitant
Fistula Hospitalization 6/14/2006 Female 154 lb 6/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatorenal Syndrome Other Serious 6/2/2006 61 Male 7/3/2006 Other Health Professional Germany
Primary
Secondary
Bradycardia Hospitalization 6/17/2006 69 Male 6/29/2006 Other Health Professional United States
Primary
Secondary
Stomatitis Hospitalization 11/24/2005 Male 119 lb 7/1/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/28/2006 Female 169 lb 7/3/2006 Physician United States
Primary
Secondary
Concomitant
Motor Dysfunction Hospitalization 1/1/2006 53 Male 6/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/29/2006 52 Male 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 6/16/2006 Female 7/7/2006 Physician Russian Federation
Primary
Secondary
Pruritus Other Serious 5/22/2006 56 Male 7/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pneumothorax Other Serious 5/4/2006 Male 7/12/2006 Physician Germany
Primary
Concomitant
Interstitial Lung Disease Other Serious 64 Female 7/6/2006 Pharmacist United States
Primary
Concomitant
Interstitial Lung Disease Other Serious 64 Female 7/5/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 3/8/2005 67 Female 7/17/2006 Consumer United States
Primary
Secondary
Vomiting Life Threatening 5/11/2006 70 Female 176 lb 7/18/2006 Physician United States
Primary
Secondary
Pulmonary Embolism Hospitalization 61 Male 179 lb 5/31/2006 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 69 Male 5/31/2006 Other Health Professional United States
Primary
Concomitant
Confusional State Life Threatening 4/9/2006 80 Male 7/14/2006 Physician France
Primary
Secondary
Pulmonary Oedema Death 6/21/2006 58 Male 7/21/2006 Physician Japan
Primary
Secondary
Vomiting Life Threatening 5/1/2006 65 Female 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 67 Male 250 lb 7/19/2006 United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/18/2005 Female 7/24/2006 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/17/2006 63 Female 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 5/25/2006 Male 166 lb 7/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/31/2005 Male 7/27/2006 Consumer United States
Primary
Secondary
Vomiting Life Threatening 5/1/2006 65 Female 7/20/2006 Physician United States
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 6/28/2006 67 Female 163 lb 7/28/2006 Physician Germany
Primary
Concomitant
Myocardial Ischaemia Hospitalization 7/10/2006 Male 7/28/2006 Other Health Professional Russian Federation
Primary
Secondary
Vomiting 5/2/2006 67 Male 250 lb 7/21/2006 United States
Primary
Secondary
Concomitant
Enterocutaneous Fistula Hospitalization 7/5/2005 Female 8/1/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 5/1/2006 Female 8/3/2006 Physician United States
Primary
Secondary
Somnolence Death 7/11/2006 Male 146 lb 8/3/2006 Other Health Professional Italy
Primary
Secondary
Mental Status Changes Other Serious 11/6/2005 Male 8/4/2006 Physician United States
Primary
Secondary
Renal Tubular Necrosis Life Threatening 5/9/2006 Female 8/4/2006 Physician United States
Primary
Secondary
Concomitant
Splenomegaly Other Serious 9/1/2005 Female 8/8/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 7/15/2006 53 Male 190 lb 8/2/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Death 5/23/2006 Male 159 lb 8/8/2006 Physician Japan
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 7/13/2006 46 Male 147 lb 8/2/2006 Other Health Professional United States
Primary
Concomitant
Renal Impairment Hospitalization 10/24/2005 Male 8/11/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/24/2005 52 Male 149 lb 8/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Death 5/23/2006 Male 159 lb 8/15/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/4/2006 30 Male 8/8/2006 Physician Canada
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 7/28/2006 Male 8/9/2006 Physician United States
Primary
Concomitant
Palpitations Hospitalization 7/5/2006 66 Female 82 lb 8/10/2006 Other Health Professional United States
Primary
Secondary
Sudden Death Death 7/5/2006 Female 8/16/2006 Other Health Professional United States
Primary
Secondary
Somnolence Hospitalization 8/4/2006 Female 73 lb 8/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 5/23/2006 70 Male 8/12/2006 Physician United States
Primary
Secondary
Concomitant
Urticaria 7/20/2006 54 Male 176 lb 7/20/2006 Other Health Professional United States
Primary
Secondary
Tachycardia Hospitalization 10/24/2005 52 Male 149 lb 8/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious 8/1/2006 42 Female 8/18/2006 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 7/15/2006 53 Male 190 lb 8/21/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/29/2006 52 Male 8/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/15/2006 53 Male 190 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 7/27/2006 69 Male 8/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 5/19/2006 75 Male 185 lb 8/7/2006 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 5/25/2006 54 Male 157 lb 8/3/2006 Consumer United States
Primary
Secondary
Intestinal Perforation Other Serious 8/1/2006 42 Female 8/25/2006 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 6/8/2006 47 Male 8/2/2006 Physician United States
Primary
Secondary
Staphylococcal Infection Hospitalization 2/2/2006 55 Male 205 lb 8/23/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperammonaemia Other Serious 8/14/2006 75 Male 9/4/2006 Physician Japan
Primary
Secondary
Wrong Drug Administered Other Serious 7/13/2006 46 Male 147 lb 8/30/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/9/2006 60 Female 101 lb 9/1/2006 United States
Primary
Secondary
Concomitant
Pyonephrosis Hospitalization 5/5/2005 61 Male 9/1/2006 Other Health Professional Hungary
Primary
Secondary
Palpitations Life Threatening 7/5/2006 66 Female 82 lb 9/6/2006 Physician United States
Primary
Secondary
Vena Cava Thrombosis Life Threatening 6/20/2005 43 Male 187 lb 9/5/2006 Physician Brazil
Primary
Concomitant
Speech Disorder Other Serious 5/24/2006 63 Male 9/6/2006 Pharmacist Canada
Primary
Concomitant
Hypovolaemia Hospitalization 3/25/2005 67 Male 230 lb 9/9/2006 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/6/2006 67 Female 104 lb 9/19/2006 Other Health Professional United States
Primary
Secondary
Malignant Hypertension Other Serious 9/19/2006 Physician United States
Primary
Secondary
Depressed Level Of Consciousness Other Serious 8/6/2006 42 Male 9/20/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 5/24/2006 9/20/2006 Other Health Professional United States
Primary
Secondary
Peritonitis Other Serious 8/1/2006 42 Female 9/20/2006 Other Health Professional United States
Primary
Concomitant
Skin Ulcer Other Serious 7/17/2006 70 Male 9/15/2006 Other Health Professional United States
Primary
Secondary
Vena Cava Thrombosis Life Threatening 6/20/2005 43 Male 187 lb 9/15/2006 Physician Brazil
Primary
Concomitant
Respiratory Arrest Death 7/27/2006 Male 130 lb 9/21/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenia Life Threatening 7/12/2006 Male 128 lb 9/25/2006 Physician Japan
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 6/5/2006 Female 63 lb 9/25/2006 Physician United States
Primary
Secondary
Transient Ischaemic Attack Hospitalization 7/31/2006 77 Female 9/25/2006 Physician United States
Primary
Secondary
Vomiting Other Serious 8/10/2006 52 Male 163 lb 9/18/2006 United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Required Intervention 6/9/2006 56 Male 176 lb 9/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 7/17/2006 73 Male 176 lb 10/2/2006 Other Health Professional United States
Primary
Secondary
Wrong Drug Administered Other Serious 7/13/2006 46 Male 147 lb 9/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 9/22/2005 Female 10/4/2006 Physician Greece
Primary
Secondary
Thrombosis Other Serious 2/15/2006 Male 10/4/2006 Physician Canada
Primary
Secondary
Concomitant
Septic Shock Death 11/1/2005 Male 10/6/2006 Physician United States
Primary
Secondary
Neurotoxicity Other Serious Female 10/4/2006 Other Health Professional United States
Primary
Secondary
Sudden Death Death 9/9/2006 Female 10/10/2006 Other Health Professional United States
Primary
Secondary
Fatigue Hospitalization 10/5/2006 Male 206 lb 10/11/2006 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Death 10/2/2006 77 Male 10/13/2006 Physician Japan
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 7/31/2006 77 Female 10/6/2006 United States
Primary
Secondary
Thrombosis Hospitalization 9/4/2006 Male 10/16/2006 Other Health Professional United States
Primary
Secondary
Small Intestinal Obstruction Hospitalization 9/6/2006 41 Male 10/7/2006 Physician United States
Primary
Secondary
Intestinal Perforation Life Threatening 9/22/2005 Female 10/17/2006 Physician Greece
Primary
Secondary
Neutrophil Count Decreased Hospitalization 9/1/2006 62 Male 10/19/2006 Physician United States
Primary
Secondary
Skin Exfoliation Hospitalization 7/21/2003 Male 159 lb 10/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Somnolence Death 7/11/2006 Male 146 lb 10/20/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 1/13/2006 25 Male 187 lb 10/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Mallory-weiss Syndrome Hospitalization 8/25/2006 Female 10/23/2006 Physician
Primary
Secondary
Transient Ischaemic Attack Hospitalization 7/31/2006 77 Female 10/25/2006 Physician United States
Primary
Secondary
Depressed Level Of Consciousness Other Serious 8/7/2006 42 Male 10/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 7/13/2006 46 Male 147 lb 10/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Pressure Increased Hospitalization 8/5/2005 57 Male 161 lb 10/19/2006 Other Health Professional United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 7/1/2005 Male 10/30/2006 Physician United States
Primary
Secondary
Concomitant

Drug Data