Leucovorin Calcium combined with Ondansetron

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tremor Other Serious 5/25/2005 69 Male 132 lb 1/4/2006 Physician Switzerland
Primary
Secondary
Concomitant
Post Procedural Vomiting Life Threatening 9/30/2005 62 Male 166 lb 1/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Syndrome Required Intervention 11/1/2005 23 Female 139 lb 12/5/2005 United States
Primary
Concomitant
Stridor Other Serious 1/9/2006 Female 161 lb 1/31/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Fatigue Hospitalization 12/1/2005 73 Female 2/28/2006 Physician Canada
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/30/2005 63 Female 119 lb 2/16/2006 Physician Italy
Primary
Concomitant
Vomiting Other Serious 11/11/2005 Female 93 lb 3/8/2006 Pharmacist Ireland
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/30/2005 63 Female 119 lb 6/14/2006 Physician Italy
Primary
Concomitant
Renal Failure Acute Hospitalization 7/26/2006 54 Female 130 lb 9/21/2006 Physician France
Primary
Secondary
Ventricular Dysfunction Hospitalization 9/28/2006 61 Male 10/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 1/19/2006 Female 11/17/2006 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 12/29/2006 Male 192 lb 1/5/2007 Other Health Professional
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 12/29/2006 Male 192 lb 1/17/2007 Other Health Professional
Primary
Secondary
Concomitant
Deep Vein Thrombosis Required Intervention 12/20/2006 70 Male 218 lb 1/10/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 12/29/2006 Male 192 lb 2/13/2007 Other Health Professional
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/10/2004 Male 101 lb 2/16/2007 Other Health Professional Thailand
Primary
Secondary
Concomitant
Mucosal Inflammation Life Threatening 10/22/2006 76 Male 163 lb 2/16/2007 Physician Spain
Primary
Secondary
Concomitant
Confusional State Other Serious 3/6/2007 Female 128 lb 3/14/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 3/7/2007 Female 128 lb 5/7/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/24/2007 Male 143 lb 5/22/2007 Other Health Professional Hungary
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/24/2007 Male 143 lb 6/4/2007 Other Health Professional Hungary
Primary
Secondary
Concomitant
Hiccups 4/25/2007 Male 147 lb 6/4/2007 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 6/2/2007 Female 6/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Vasovagal Other Serious 6/6/2007 Female 163 lb 6/14/2007 Other Health Professional Chile
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/14/2007 Female 6/15/2007 Physician Italy
Primary
Concomitant
Hypotension Hospitalization 4/24/2007 Male 143 lb 6/15/2007 Other Health Professional Hungary
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 6/2/2007 Female 6/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Presyncope Other Serious 6/19/2007 Male 175 lb 6/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Vasovagal Other Serious 6/6/2007 Female 163 lb 6/27/2007 Other Health Professional Chile
Primary
Secondary
Concomitant
Presyncope Other Serious 6/19/2007 Male 175 lb 6/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Impetigo Hospitalization 6/4/2007 Male 6/28/2007 Physician Hungary
Primary
Concomitant
Confusional State Other Serious 3/6/2007 Female 128 lb 7/5/2007 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Impetigo Hospitalization 6/4/2007 Male 7/18/2007 Physician Hungary
Primary
Concomitant
Pancytopenia Hospitalization 3/7/2007 Female 128 lb 7/23/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/1/2007 Male 7/23/2007 Physician Poland
Primary
Concomitant
Pulmonary Oedema Hospitalization 55 Female 7/26/2007
Primary
Concomitant
Thrombocytopenia Life Threatening 6/21/2007 Male 8/2/2007 Physician Poland
Primary
Concomitant
Pulse Absent Hospitalization 7/16/2007 61 Male 8/24/2007 Physician Canada
Primary
Concomitant
Pyoderma Hospitalization 7/31/2007 Female 8/27/2007 Physician Hungary
Primary
Concomitant
Staphylococcal Impetigo Hospitalization 5/29/2007 Male 8/31/2007 Physician Hungary
Primary
Concomitant
Pulse Absent Hospitalization 7/16/2007 61 Male 8/31/2007 Physician Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 21 Female 9/5/2007 Other Health Professional United States
Primary
Secondary
General Physical Health Deterioration Hospitalization 8/21/2007 Female 91 lb 9/7/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 5/31/2007 Male 9/19/2007 Physician Argentina
Primary
Concomitant
General Physical Health Deterioration Hospitalization 8/21/2007 Female 91 lb 9/19/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Testicular Pain Disability 8/28/2007 Male 158 lb 9/19/2007 Consumer United Kingdom
Primary
Concomitant
Folliculitis Hospitalization 9/5/2007 Female 11/13/2007 Physician Italy
Primary
Concomitant
Folliculitis Hospitalization 9/5/2007 Female 11/29/2007 Physician Italy
Primary
Concomitant
Pulmonary Embolism Disability 5/16/2007 Female 12/14/2007 Physician Hungary
Primary
Concomitant
Gastric Haemorrhage Hospitalization 8/3/2007 Female 93 lb 12/18/2007 Physician Chile
Primary
Concomitant
Vomiting Hospitalization 11/7/2007 52 Female 150 lb 12/27/2007 Canada
Primary
Concomitant
Myalgia Other Serious 9/1/2007 39 Female 133 lb 1/25/2008 Consumer United States
Primary
Concomitant
Pulmonary Embolism Disability 5/16/2007 Female 1/30/2008 Physician Hungary
Primary
Concomitant
Gastric Haemorrhage Hospitalization 8/3/2007 Female 93 lb 2/5/2008 Physician Chile
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/16/2007 Female 2/13/2008 Physician Hungary
Primary
Concomitant
Death Death 2/19/2008 Male 141 lb 3/3/2008 Poland
Primary
Secondary
Concomitant
Death Death 2/19/2008 Male 141 lb 3/7/2008 Poland
Primary
Secondary
Concomitant
Petechiae Other Serious 7/23/2007 Female 179 lb 3/10/2008 Physician Germany
Primary
Concomitant
Generalised Erythema Other Serious 11/14/2007 Female 132 lb 3/10/2008 Physician Germany
Primary
Concomitant
Vomiting Other Serious 1/8/2008 Female 121 lb 3/12/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/8/2008 Female 121 lb 3/18/2008 United Kingdom
Primary
Secondary
Concomitant
Death Death 2/19/2008 Male 141 lb 3/19/2008 Poland
Primary
Secondary
Concomitant
Conjunctivitis Infective Hospitalization 2/9/2008 Male 3/25/2008 Physician Poland
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/8/2008 Female 121 lb 3/25/2008 United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Life Threatening 3/20/2008 Female 130 lb 3/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/15/2008 43 Female 128 lb 3/26/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 1/8/2008 Female 121 lb 4/10/2008 United Kingdom
Primary
Secondary
Concomitant
Conjunctivitis Infective Hospitalization 2/9/2008 Male 4/14/2008 Physician Poland
Primary
Concomitant
Sepsis Hospitalization 3/7/2008 Female 4/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2008 Male 106 lb 4/30/2008 India
Primary
Secondary
Concomitant
Pulmonary Artery Thrombosis Other Serious 1/15/2008 Male 5/1/2008 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2008 Male 106 lb 5/2/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2008 Male 106 lb 5/9/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2008 Male 106 lb 5/21/2008 India
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 6/4/2008 67 Female 123 lb 6/13/2008 Physician Belgium
Primary
Secondary
Concomitant
Cerebrovascular Accident Life Threatening 5/8/2008 Male 183 lb 6/30/2008 Physician Germany
Primary
Secondary
Concomitant
Pain Hospitalization 7/13/2007 77 Female 7/3/2008 Physician Belgium
Primary
Concomitant
Intestinal Obstruction Hospitalization 6/4/2008 67 Female 123 lb 7/9/2008 Physician Belgium
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 6/11/2008 67 Female 123 lb 7/9/2008 Physician Belgium
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 6/11/2008 67 Female 123 lb 7/10/2008 Physician Belgium
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/12/2008 Male 52 lb 7/28/2008 Other Health Professional Brazil
Primary
Concomitant
Gingival Hyperplasia Hospitalization 7/20/2008 Male 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/29/2008 Female 114 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 8/15/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 8/15/2008 Other Health Professional Brazil
Primary
Concomitant
Torsade De Pointes Hospitalization 6/4/2007 Female 8/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gingival Hyperplasia Hospitalization 7/20/2008 Male 8/21/2008 Physician United States
Primary
Secondary
Concomitant
Dysphagia 7/23/2008 Female 9/4/2008 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Life Threatening 2/28/2008 62 Female 132 lb 9/10/2008 Physician Germany
Primary
Secondary
Concomitant
Splenomegaly Other Serious 4/24/2007 59 Male 10/6/2008 Consumer United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 4/24/2006 Male 165 lb 10/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 12/26/2007 Male 10/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/29/2008 Female 114 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Other Serious 1/12/2008 Male 52 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Syncope Other Serious 10/13/2008 49 Male 204 lb 10/13/2008 Pharmacist United States
Primary
Concomitant
Oesophagitis Hospitalization 12/26/2007 Male 10/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 10/16/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 10/16/2008 Other Health Professional Brazil
Primary
Concomitant
Drug Hypersensitivity Life Threatening 11/7/2005 Female 108 lb 10/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Chemotherapeutic Drug Level Increased Other Serious 3/11/2008 4 Male 47 lb 10/7/2008 Pharmacist United States
Primary
Concomitant
Nephropathy Toxic Hospitalization 3/1/2008 17 Male 143 lb 10/7/2008 Pharmacist United States
Primary
Concomitant
Shock Other Serious 11/30/2007 Male 35 lb 11/3/2008 Other Health Professional Brazil
Primary
Concomitant
Death Death 2/19/2008 Male 141 lb 11/17/2008 Poland
Primary
Secondary
Concomitant
Gingival Hyperplasia 7/20/2008 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious 8/5/2008 Female 130 lb 11/26/2008 Physician United States
Primary
Concomitant
Laryngospasm Other Serious 12/2/2008 Male 131 lb 12/16/2008 Other Health Professional Canada
Primary
Concomitant
Death Death 12/16/2008 12/29/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/7/2008 Female 12/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 2/19/2008 3/4/2009 Physician Poland
Primary
Secondary
Concomitant
Vomiting Death 10/14/2008 47 Male 82 lb 3/12/2009 Other Health Professional Israel
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/15/2007 Female 4/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Disease Progression Death 8/23/2007 Female 91 lb 4/22/2009 Other Health Professional Brazil
Primary
Secondary
Concomitant
Oesophageal Ulcer Other Serious 60 Female 4/22/2009 Physician United Kingdom
Primary
Concomitant
Ulcerative Keratitis Other Serious 4/8/2009 Male 218 lb 4/17/2009 Pharmacist United States
Primary
Concomitant
Blood Bilirubin Increased Required Intervention 2/22/2009 30 Female 235 lb 2/24/2009 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 7/5/2008 28 5/21/2009 Physician India
Primary
Secondary
Concomitant
Death Death 2/19/2008 65 5/21/2009 Physician Poland
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 4/29/2009 Male 192 lb 6/4/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 4/29/2009 Male 192 lb 6/10/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/5/2008 28 6/10/2009 Physician India
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 62 Male 192 lb 6/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Torsade De Pointes Hospitalization 6/2/2007 Female 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 6/28/2008 Female 130 lb 6/29/2009 Other Health Professional Portugal
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 7/7/2009 United States
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 6/18/2009 57 Male 197 lb 7/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/19/2009 Male 104 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/19/2009 Male 104 lb 7/24/2009 United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 7/31/2009 United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/20/2009 Physician United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/28/2009 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 168 lb 9/8/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 77 Female 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 7/23/2009 Female 174 lb 10/7/2009 Consumer Australia
Primary
Secondary
Concomitant
Myocardial Infarction Death 7/23/2009 Female 10/9/2009 Consumer Australia
Primary
Secondary
Concomitant
Nausea Hospitalization 5/27/2009 78 Male 11/25/2009 Physician United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 28 Female 11/30/2009 Physician Poland
Primary
Secondary
Concomitant
Malaise Other Serious 9/24/2009 76 Female 108 lb 12/9/2009 Physician United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 28 Female 12/14/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Respiratory Distress Death 10/21/2009 69 Male 197 lb 1/6/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 10/7/2009 75 Female 97 lb 1/12/2010 Physician Spain
Primary
Secondary
Concomitant
Urticaria Other Serious 17 Male 123 lb 1/15/2010 Other Health Professional Canada
Primary
Concomitant
Oxygen Saturation Decreased Disability 1/27/2010 69 Male 259 lb 1/28/2010 Pharmacist United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/5/2009 Male 3/8/2010 Physician Spain
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 168 lb 3/16/2010 United States
Primary
Secondary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Vomiting Hospitalization 3/11/2010 Female 105 lb 3/23/2010 United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 6/23/2009 78 Male 168 lb 4/6/2010 United States
Primary
Secondary
Concomitant
Hiccups Other Serious 54 Male 4/7/2010
Primary
Secondary
Paraesthesia Other Serious 13 Male 88 lb 5/3/2010 Other Health Professional Canada
Primary
Concomitant

Drug Data