Leucovorin Calcium combined with Lorazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Life Threatening 5/30/2005 Male 235 lb 1/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/28/2005 42 Female 205 lb 1/18/2006 Physician Canada
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/2/2006 70 Male 3/17/2006 Physician Thailand
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/2/2006 70 Male 3/29/2006 Physician Thailand
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 Male 250 lb 5/3/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 67 Male 250 lb 5/10/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 Male 250 lb 5/10/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/6/2006 74 Female 194 lb 5/19/2006 Physician Belgium
Primary
Concomitant
Ventricular Extrasystoles Other Serious 2/2/2006 70 Male 5/23/2006 Physician Thailand
Primary
Secondary
Concomitant
Syncope Life Threatening 5/14/2006 38 Male 5/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 67 Male 250 lb 5/31/2006 Consumer United States
Primary
Secondary
Concomitant
Streptococcal Infection Life Threatening 5/14/2006 38 Male 6/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Hospitalization 5/2/2006 71 Female 185 lb 6/12/2006 Physician Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 67 Male 250 lb 6/19/2006 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/9/2006 56 Male 176 lb 6/21/2006 Consumer United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 6/9/2006 Male 176 lb 6/30/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 67 Male 250 lb 6/26/2006 United States
Primary
Secondary
Concomitant
Pneumonia Streptococcal Life Threatening 5/14/2006 38 Male 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/9/2006 56 Male 7/11/2006 United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/9/2006 56 Male 176 lb 7/11/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/1/2006 65 Female 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 67 Male 250 lb 7/19/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/17/2006 63 Female 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Tumour Associated Fever Hospitalization 7/15/2006 Male 190 lb 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting 5/2/2006 67 Male 250 lb 7/21/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 7/28/2003 35 Female 8/4/2006 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/28/2006 74 Male 8/21/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/15/2006 53 Male 190 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/9/2006 56 Male 176 lb 6/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 6/9/2006 56 Male 176 lb 8/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/11/2006 67 Male 250 lb 8/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/9/2006 60 Female 101 lb 9/1/2006 United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Required Intervention 6/9/2006 56 Male 176 lb 9/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/28/2006 74 Male 10/11/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/28/2006 74 Male 11/13/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Hospitalization 11/9/2006 Male 174 lb 11/17/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Hospitalization 11/9/2006 Male 174 lb 11/30/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious Female 2/1/2007 Other Health Professional Canada
Primary
Concomitant
Dehydration Hospitalization 2/4/2006 Male 2/16/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombosis Hospitalization 2/25/2006 Male 282 lb 2/27/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 5/2/2006 67 Male 250 lb 2/28/2007 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 2/4/2006 Male 3/14/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 6/2/2007 Female 6/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 6/2/2007 Female 6/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/16/2007 Male 215 lb 7/25/2007 United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 8/21/2007 Male 9/5/2007 Consumer Taiwan, Province Of China
Primary
Concomitant
Stomatitis Hospitalization 7/22/2007 Female 9/6/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 2/2/2006 Male 9/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 5/31/2007 Male 9/19/2007 Physician Argentina
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/19/2007 Female 125 lb 11/22/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/19/2007 Female 125 lb 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/22/2007 Female 12/20/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/7/2007 52 Female 150 lb 12/27/2007 Canada
Primary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Angina Pectoris Life Threatening 3/20/2008 Female 130 lb 3/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/15/2008 43 Female 128 lb 3/26/2008 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 9/6/2007 59 Female 3/28/2008 Consumer United States
Primary
Concomitant
Carotid Artery Occlusion Hospitalization 3/27/2008 60 4/9/2008 Other Health Professional
Primary
Secondary
Concomitant
Carotid Artery Occlusion Hospitalization 3/27/2008 60 Male 4/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/14/2008 Male 220 lb 4/25/2008 Physician Switzerland
Primary
Concomitant
Sepsis Hospitalization 3/7/2008 Female 4/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Hospitalization 3/27/2008 60 Male 4/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 4/8/2008 Male 88 lb 4/30/2008 India
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 4/8/2008 Male 88 lb 5/14/2008 India
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/28/2006 74 Male 207 lb 6/5/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/1/2006 74 Male 207 lb 6/12/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/1/2006 74 Male 207 lb 6/16/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/1/2006 74 Male 207 lb 6/18/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Pain Hospitalization 7/13/2007 77 Female 7/3/2008 Physician Belgium
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 5/14/2008 Female 7/24/2008 Physician United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 2/14/2008 Male 220 lb 7/29/2008 Physician Switzerland
Primary
Concomitant
Hypokalaemia Hospitalization 5/31/2008 50 Male 220 lb 8/1/2008 Consumer United States
Primary
Secondary
Concomitant
Torsade De Pointes Hospitalization 6/4/2007 Female 8/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dysphagia 7/23/2008 Female 9/4/2008 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Other Serious 9/8/2008 Female 192 lb 9/8/2008 Pharmacist United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 9/4/2008 Female 148 lb 9/10/2008 United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 9/15/2008 Consumer France
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/17/2008 Female 120 lb 9/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased 11/1/2007 63 Female 154 lb 9/25/2008 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 5/17/2008 Female 120 lb 9/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 9/13/2008 Male 10/7/2008 Physician Germany
Primary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 11/24/2008 Consumer France
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 4/8/2008 Male 88 lb 11/25/2008 India
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/9/2008 Female 12/5/2008 Physician Germany
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 12/17/2008 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/7/2008 Female 12/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/16/2008 Female 130 lb 12/23/2008 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/3/2007 Female 1/7/2009 Physician Spain
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 2/14/2008 Male 220 lb 1/14/2009 Physician Switzerland
Primary
Concomitant
Arrhythmia Death 1/1/2009 Female 190 lb 2/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Other Serious 9/13/2008 Male 2/9/2009 Physician Germany
Primary
Concomitant
Haematemesis Hospitalization 3/21/2006 59 Male 2/27/2009 Physician France
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 2/7/2009 Female 168 lb 3/6/2009 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 11/15/2007 Female 4/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Bilirubin Increased Required Intervention 2/22/2009 30 Female 235 lb 2/24/2009 Pharmacist United States
Primary
Concomitant
Hypokalaemia Other Serious 4/8/2008 55 5/21/2009 Physician India
Primary
Secondary
Concomitant
Disease Progression Other Serious 5/21/2005 Male 158 lb 5/26/2009 Other Health Professional United States
Primary
Concomitant
Torsade De Pointes Hospitalization 6/2/2007 Female 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/3/2007 Female 6/30/2009 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2009 67 Female 150 lb 8/14/2009 Physician United States
Primary
Concomitant
Hypercalcaemia Hospitalization 2/13/2008 Male 133 lb 8/20/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hypercalcaemia Hospitalization 2/13/2008 Male 133 lb 9/7/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/1/2009 Male 190 lb 9/17/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 4/27/2009 Female 146 lb 10/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 5/27/2009 78 Male 11/25/2009 Physician United States
Primary
Secondary
Concomitant
Hypertension Hospitalization 1/4/2010 Male 220 lb 1/20/2010 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 17 Male 123 lb 1/15/2010 Other Health Professional Canada
Primary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Hypertension Hospitalization 1/4/2010 Male 220 lb 2/6/2010 Physician United States
Primary
Secondary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Arrhythmia Death 1/1/2009 81 Female 190 lb 4/22/2010 Physician United States
Primary
Secondary
Concomitant
Hypertension Hospitalization 1/4/2010 48 Male 220 lb 4/26/2010 Physician France
Primary
Secondary
Concomitant
Paraesthesia Other Serious 13 Male 88 lb 5/3/2010 Other Health Professional Canada
Primary
Concomitant
Vomiting Death 1/18/2008 70 Female 185 lb 5/7/2010 Lawyer United States
Primary
Concomitant
Wheelchair User Other Serious 10/9/2001 65 Female 169 lb 6/15/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/9/2010 40 Female 6/25/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 6/9/2010 40 Female 7/20/2010 Physician United States
Primary
Secondary
Concomitant
Neutrophil Count Increased Other Serious 5/23/2010 55 Female 108 lb 7/27/2010 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/10/2008 82 Male 150 lb 7/21/2010 Physician Spain
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 5/24/2007 60 Male 139 lb 8/18/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 6/24/2007 60 Male 139 lb 8/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 10/9/2001 65 Female 169 lb 9/1/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 10/9/2001 65 Female 169 lb 9/6/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/9/2001 65 Female 169 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 9/15/2010 68 Female 140 lb 10/4/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 1/4/2010 48 Male 220 lb 10/29/2010 Physician France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/8/2010 70 Female 210 lb 11/23/2010 Physician Canada
Primary
Concomitant
Wound Drainage Other Serious 10/9/2001 65 Female 169 lb 11/24/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Required Intervention 1/4/2010 48 Male 11/29/2010 Physician United States
Primary
Secondary
Concomitant
Headache Other Serious 9/1/2007 50 Male 194 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective 10/1/2010 76 Female 1/30/2011 Consumer United States
Primary
Concomitant
Perirectal Abscess 2/15/2011 34 Male 167 lb 2/15/2011 United States
Primary
Secondary
Concomitant
Burning Sensation Hospitalization Male 101 lb 3/3/2011 Other Health Professional Canada
Primary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/16/2010 14 Female 130 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Psychomotor Hyperactivity Hospitalization 3/22/2011 79 Male 5/17/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 5/13/2011 67 Male 172 lb 6/1/2011 Physician Spain
Primary
Secondary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 6/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/2/2011 23 Female 108 lb 6/10/2011 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/2/2011 23 Female 108 lb 6/14/2011 Physician United States
Primary
Secondary
Concomitant
Pressure Of Speech Hospitalization 77 Female 6/17/2011 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 6/13/2011 38 Female 198 lb 9/13/2011 Physician Switzerland
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 8/27/2009 60 Female 172 lb 9/13/2011 Physician Spain
Primary
Secondary
Concomitant

Drug Data