Leucovorin Calcium combined with Lisinopril

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oesophageal Carcinoma Death Male 195 lb 1/3/2006 Physician United States
Primary
Concomitant
Swollen Tongue Hospitalization 8/8/2005 64 Female 189 lb 12/1/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 3/14/2006 61 Female 157 lb 3/29/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Vertigo Hospitalization 11/29/2005 62 Female 3/31/2006 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Pain Stimuli Hospitalization 12/14/2005 68 Female 143 lb 4/4/2006 Physician United States
Primary
Concomitant
Duodenal Perforation Required Intervention 2/12/2006 81 Male 143 lb 3/1/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 4/25/2006 66 Male 6/13/2006 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Other Serious 6/9/2006 Male 176 lb 6/30/2006 Consumer United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/9/2006 56 Male 176 lb 7/11/2006 Consumer United States
Primary
Secondary
Concomitant
Coma Other Serious 5/1/2005 75 Male 7/19/2006 Consumer United States
Primary
Concomitant
Walking Aid User Hospitalization 11/29/2005 62 Female 7/20/2006 Physician United States
Primary
Secondary
Concomitant
Tumour Associated Fever Hospitalization 7/15/2006 Male 190 lb 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Life Threatening 5/9/2006 Female 8/4/2006 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Life Threatening 5/9/2006 58 Female 157 lb 8/8/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/15/2006 53 Male 190 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 6/9/2006 56 Male 176 lb 8/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Required Intervention 6/9/2006 56 Male 176 lb 9/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 1/26/2006 69 Male 12/1/2006 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Death Female 116 lb 12/22/2006 Physician United States
Primary
Concomitant
Syncope Hospitalization 10/28/2006 63 Female 12/18/2006 Other Health Professional United States
Primary
Secondary
Subdural Haematoma Hospitalization 1/19/2007 73 Male 2/16/2007 Other Health Professional United States
Primary
Concomitant
Hydronephrosis Other Serious 2/22/2007 54 Female 4/12/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Life Threatening 5/9/2006 Female 157 lb 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 5/8/2006 Female 157 lb 4/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 5/8/2006 Female 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Prostate Cancer Other Serious Male 217 lb 6/11/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/10/2007 69 Female 187 lb 6/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/25/2007 66 Female 6/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 4/23/2007 Female 6/15/2007 Physician United Kingdom
Primary
Secondary
Enterocutaneous Fistula Hospitalization 11/15/2007 Male 159 lb 11/26/2007 United States
Primary
Concomitant
Syncope Other Serious 1/23/2006 Female 203 lb 11/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Injection Site Pain 5/1/2007 Female 150 lb 12/8/2007 Consumer
Primary
Concomitant
Enterocutaneous Fistula Hospitalization 11/15/2007 Male 159 lb 12/10/2007 United States
Primary
Concomitant
Rash Hospitalization 9/23/2007 72 Male 179 lb 12/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Enterocutaneous Fistula Hospitalization 10/24/2007 Male 12/17/2007 United States
Primary
Concomitant
Respiratory Failure Hospitalization 2/24/2005 Male 177 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2/24/2005 Male 177 lb 2/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Enterocutaneous Fistula Hospitalization 10/24/2007 Male 159 lb 2/21/2008 United States
Primary
Concomitant
Accidental Exposure 1/31/2008 Female 180 lb 3/15/2008 United States
Primary
Concomitant
Urticaria Other Serious 12/21/2006 Female 179 lb 3/28/2008 Physician United States
Primary
Concomitant
Urticaria Other Serious 1/31/2008 Female 3/28/2008 Consumer United States
Primary
Secondary
Concomitant
Carotid Artery Occlusion Hospitalization 3/27/2008 60 4/9/2008 Other Health Professional
Primary
Secondary
Concomitant
Carotid Artery Occlusion Hospitalization 3/27/2008 60 Male 4/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 3/12/2007 78 Female 2/28/2008 Physician United States
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 3/27/2008 60 Male 4/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/30/2007 57 Female 2/28/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 11/1/2006 Male 4/29/2008 Physician United Kingdom
Primary
Secondary
Mental Disorder Hospitalization 2/12/2008 Female 5/2/2008 Physician United States
Primary
Secondary
Concomitant
Flushing Hospitalization 10/17/2007 Female 170 lb 5/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 6/9/2008 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Flushing Hospitalization 10/17/2007 Female 170 lb 6/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2006 Female 139 lb 6/20/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 6/23/2008 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 7/16/2008 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 7/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 1/10/2007 Male 206 lb 7/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thyroid Neoplasm Other Serious 5/19/2004 Female 184 lb 8/8/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 61 Female 199 lb 8/21/2008 United States
Primary
Concomitant
Ejection Fraction Decreased Other Serious 7/1/2008 66 Male 174 lb 9/4/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 5/1/2008 Female 131 lb 9/13/2008 Consumer United States
Primary
Concomitant
Ejection Fraction Decreased Other Serious 7/1/2008 66 Male 174 lb 9/23/2008 Consumer United States
Primary
Concomitant
Weight Decreased 11/1/2007 63 Female 154 lb 9/25/2008 Consumer United States
Primary
Concomitant
Colitis Hospitalization 8/31/2008 Male 170 lb 10/1/2008 Physician United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 1/10/2007 Male 206 lb 10/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Hospitalization 8/31/2008 Male 170 lb 10/8/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 Female 138 lb 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Metastasis Other Serious 68 Male 12/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/16/2008 Male 174 lb 12/17/2008 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 59 Female 216 lb 1/12/2009
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 3/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Flushing Hospitalization 10/17/2007 Female 170 lb 3/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Enterocutaneous Fistula Hospitalization 10/24/2007 Male 159 lb 3/9/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Hypoxia Hospitalization 11/12/2008 51 Female 128 lb 4/22/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/16/2009 Male 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 10/17/2007 50 Female 170 lb 4/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/17/2009 Male 174 lb 5/26/2009 United States
Primary
Secondary
Concomitant
Anal Ulcer Hospitalization 3/30/2009 Female 139 lb 6/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulse Absent Hospitalization 4/28/2009 Male 171 lb 6/17/2009 Other Health Professional United States
Primary
Concomitant
Salivary Gland Mass Other Serious 1/1/2008 38 Female 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 7/7/2009 United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/7/2008 69 Female 109 lb 7/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 7/31/2009 United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Hyperosmolar State Hospitalization 4/23/2009 Female 8/12/2009 Physician United States
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 2/12/2008 Female 8/13/2009 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/20/2009 Physician United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/28/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 168 lb 9/8/2009 Physician United States
Primary
Secondary
Concomitant
Injection Site Extravasation 1/31/2008 Female 180 lb 9/12/2009 United States
Primary
Concomitant
Hyperosmolar State Hospitalization 4/23/2009 Female 9/23/2009 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 10/1/2009 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 77 Female 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 10/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 11/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 12/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 12/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 12/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 9/17/2009 Male 12/14/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 12/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 1/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Death 10/21/2009 69 Male 197 lb 1/6/2010 Pharmacist United States
Primary
Concomitant
Nervous System Disorder Other Serious 9/17/2009 Male 187 lb 1/8/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 1/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 1/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 1/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/21/2006 Female 139 lb 1/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/7/2008 69 Female 109 lb 1/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 9/17/2009 Male 187 lb 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 168 lb 3/16/2010 United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 6/23/2009 78 Male 168 lb 4/6/2010 United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 10/19/2006 69 Male 151 lb 4/6/2010 Physician United States
Primary
Secondary
Concomitant
Epiglottitis Hospitalization 4/25/2010 71 Female 185 lb 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Epiglottitis Hospitalization 4/25/2010 71 Female 185 lb 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/12/2009 72 Male 5/14/2010 Consumer United States
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Death 6/26/2010 42 Female 7/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/12/2009 72 Male 7/16/2010 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 51 Female 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Colitis Hospitalization 7/26/2010 58 Male 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 10/17/2007 50 Female 170 lb 8/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/8/2008 56 Male 8/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/8/2008 56 Male 8/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Hospitalization 7/26/2010 58 Male 10/4/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/15/2010 73 Male 10/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/15/2010 73 Male 11/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 2/12/2008 12/1/2010 Other Health Professional Algeria
Primary
Secondary
Concomitant
Syncope Hospitalization 1/6/2011 78 Male 146 lb 1/6/2011 United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 167 lb 1/27/2011 Consumer United States
Primary
Secondary
Concomitant
Eyelid Ptosis Hospitalization 1/15/2011 79 Female 159 lb 1/21/2011 Physician United States
Primary
Secondary
Concomitant
Diabetic Foot Infection Hospitalization 6/23/2009 78 Male 167 lb 3/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetic Foot Infection Hospitalization 6/23/2009 78 Male 167 lb 3/9/2011 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 6/23/2009 78 Male 167 lb 3/22/2011 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 10/30/2010 74 Male 190 lb 4/25/2011 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious 12/30/2010 52 Male 181 lb 5/18/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 7/5/2005 77 Male 6/21/2011 Other Health Professional Austria
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 5/16/2011 66 Female 7/5/2011 Consumer United States
Primary
Concomitant
Paronychia Hospitalization 8/31/2010 72 Male 176 lb 9/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Fatigue Hospitalization 69 Male 9/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Enterocutaneous Fistula Hospitalization 10/24/2007 72 Male 159 lb 10/3/2011 Other Health Professional United States
Primary
Concomitant
Pneumonitis Death 69 Male 10/6/2011 Other Health Professional United States
Primary
Concomitant
Fatigue Other Serious 69 Male 10/27/2011 Other Health Professional United States
Primary
Concomitant
Sensory Disturbance 1/16/2011 56 Female 102 lb 10/29/2011 Consumer United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 10/27/2011 62 Male 11/2/2011 Physician United States
Primary
Concomitant
Muscular Weakness 2/27/2011 72 Male 174 lb 11/3/2011 Consumer United States
Primary
Secondary
Concomitant

Drug Data