Letairis combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain In Extremity Other Serious 7/26/2007 Female 112 lb 8/30/2007 Other Health Professional United States
Primary
Concomitant
Oedema Hospitalization 8/21/2007 Female 249 lb 10/4/2007 Pharmacist United States
Primary
Concomitant
Prothrombin Time Abnormal Other Serious 9/25/2007 Female 11/1/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization Female 249 lb 11/9/2007 Physician United States
Primary
Concomitant
Pseudomonas Infection Other Serious 10/1/2007 51 Female 11/21/2007 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 10/31/2007 Female 80 lb 12/5/2007 Pharmacist United States
Primary
Concomitant
Fatigue Other Serious 10/1/2007 Female 143 lb 12/5/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization Female 203 lb 1/15/2008 Physician United States
Primary
Concomitant
Fluid Overload Hospitalization 12/7/2007 Female 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 10/31/2007 Female 80 lb 1/23/2008 Pharmacist United States
Primary
Concomitant
Death Death 12/16/2007 Male 1/29/2008 Physician United States
Primary
Concomitant
Tachycardia Other Serious 1/4/2008 Female 201 lb 1/29/2008 Other Health Professional United States
Primary
Concomitant
Blood Potassium Increased Other Serious 1/3/2008 Female 148 lb 1/30/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 12/31/2007 Male 216 lb 1/31/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 12/31/2007 Male 216 lb 2/8/2008 Consumer United States
Primary
Concomitant
Death Other Serious 1/3/2008 Female 148 lb 2/12/2008 Other Health Professional United States
Primary
Concomitant
Haemoptysis Hospitalization 1/1/2008 Female 80 lb 2/15/2008 Other Health Professional United States
Primary
Concomitant
Prothrombin Time Abnormal Other Serious 9/25/2007 Female 2/18/2008 Other Health Professional United States
Primary
Concomitant
Hypocoagulable State Hospitalization Female 192 lb 3/12/2008 Pharmacist United States
Primary
Concomitant
Rash Other Serious Male 212 lb 3/12/2008 Other Health Professional United States
Primary
Concomitant
Nasopharyngitis Male 3/17/2008 Consumer United States
Primary
Concomitant
Hypocoagulable State Hospitalization Female 192 lb 3/18/2008 Pharmacist United States
Primary
Concomitant
Hypocoagulable State Hospitalization Female 192 lb 3/25/2008 Physician United States
Primary
Concomitant
Rash Disability 12/27/2007 Male 296 lb 3/25/2008 Consumer United States
Primary
Concomitant
Hypocoagulable State Hospitalization Female 192 lb 3/28/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 10/10/2007 Female 250 lb 4/30/2008 Physician United States
Primary
Concomitant
Malaise Life Threatening Male 5/1/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased Other Serious Female 5/1/2008 Other Health Professional United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 4/10/2008 Female 5/12/2008 Pharmacist United States
Primary
Secondary
Concomitant
Treatment Noncompliance Death 5/11/2008 Female 185 lb 5/27/2008 Other Health Professional United States
Primary
Concomitant
Central Line Infection Hospitalization 1/16/2008 64 Male 5/30/2008 Consumer United States
Primary
Secondary
Concomitant
Serum Sickness Other Serious Female 220 lb 5/30/2008 Consumer United States
Primary
Concomitant
Hyperlipidaemia Hospitalization 4/2/2008 Female 230 lb 6/4/2008 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 11/23/2007 Male 190 lb 6/17/2008 Other Health Professional United States
Primary
Concomitant
Chest Discomfort Hospitalization 8/21/2007 Female 249 lb 6/20/2008 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Hospitalization 9/26/2007 Female 223 lb 7/3/2008 Other Health Professional United States
Primary
Concomitant
Central Line Infection Hospitalization 6/20/2008 Female 7/10/2008 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 1/11/2008 Female 7/11/2008 Physician United States
Primary
Concomitant
Catheter Related Infection Hospitalization 6/20/2008 46 Female 7/14/2008 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization Female 250 lb 7/17/2008 Physician United States
Primary
Concomitant
Clostridium Difficile Colitis Other Serious 6/27/2008 Female 175 lb 8/4/2008 Physician United States
Primary
Concomitant
Death Death 8/7/2008 Female 145 lb 8/14/2008 Consumer United States
Primary
Concomitant
Dry Mouth Disability 8/5/2008 Female 8/21/2008 Consumer United States
Primary
Concomitant
Death Death Female 9/16/2008 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 8/27/2008 Female 9/23/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization Female 10/9/2008 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Bacterial Other Serious 9/30/2008 Female 10/10/2008 Consumer United States
Primary
Concomitant
Blood Potassium Decreased Hospitalization Female 83 lb 10/10/2008 Consumer United States
Primary
Concomitant
Right Ventricular Failure Other Serious Female 150 lb 10/14/2008 Physician United States
Primary
Concomitant
Swelling Face Other Serious 8/27/2008 Female 10/16/2008 Physician United States
Primary
Concomitant
Photopsia Other Serious Male 160 lb 10/16/2008 Consumer United States
Primary
Concomitant
Photopsia Other Serious Male 160 lb 10/28/2008 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Death Female 11/3/2008 Physician United States
Primary
Concomitant
Death Death 10/24/2008 Male 220 lb 11/4/2008 Consumer United States
Primary
Concomitant
Hospitalisation Death 10/24/2008 Male 220 lb 11/10/2008 Physician United States
Primary
Concomitant
Central Line Infection Hospitalization Female 11/13/2008 Consumer United States
Primary
Concomitant
Blood Potassium Decreased Hospitalization Female 83 lb 11/17/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization Female 11/24/2008 Physician United States
Primary
Concomitant
Lethargy Hospitalization Female 11/24/2008 Consumer United States
Primary
Concomitant
Chest Discomfort Hospitalization 11/12/2008 Female 11/26/2008 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization Female 12/3/2008 Physician United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 12/8/2008 Female 12/17/2008 Consumer United States
Primary
Concomitant
Death Death Male 225 lb 12/23/2008 Consumer United States
Primary
Concomitant
Adverse Drug Reaction Hospitalization Female 150 lb 12/30/2008 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Death Male 225 lb 1/6/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/27/2008 Female 1/7/2009 Other Health Professional United States
Primary
Concomitant
Thyroid Function Test Abnormal Hospitalization Female 179 lb 1/9/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 1/5/2009 Female 1/19/2009 Consumer United States
Primary
Concomitant
Death Death 1/9/2009 Female 179 lb 1/20/2009 Consumer United States
Primary
Concomitant
Pain Other Serious Female 1/21/2009 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal Hospitalization 12/24/2008 Female 179 lb 1/21/2009 Physician United States
Primary
Concomitant
Renal Failure Death 1/1/2009 Female 1/22/2009 Physician United States
Primary
Concomitant
Death Death 1/9/2009 Female 179 lb 1/29/2009 Physician United States
Primary
Concomitant
Oedema Hospitalization 12/14/2008 Female 150 lb 2/5/2009 Physician United States
Primary
Concomitant
Death Death 1/26/2009 Female 105 lb 2/11/2009 Consumer United States
Primary
Concomitant
Death Death 1/29/2009 Female 2/12/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Bacterial Other Serious 9/30/2008 Female 2/13/2009 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/28/2009 Female 231 lb 2/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/28/2009 72 Female 2/20/2009 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Death 2/18/2009 Female 2/20/2009 Pharmacist United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization Male 140 lb 2/25/2009 Consumer United States
Primary
Concomitant
Rash Death 10/1/2008 Female 2/27/2009 Physician United States
Primary
Concomitant
Chest Pain Hospitalization Female 195 lb 3/3/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/28/2009 72 Female 3/3/2009 Physician United States
Primary
Secondary
Concomitant
Rectal Polyp Hospitalization 1/30/2009 Male 3/4/2009 Consumer United States
Primary
Concomitant
Death Death 1/8/2009 Male 162 lb 3/4/2009 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization Female 195 lb 3/5/2009 Physician United States
Primary
Concomitant
Abdominal Neoplasm Hospitalization Male 230 lb 3/5/2009 Consumer United States
Primary
Concomitant
Death Death 2/22/2009 Female 162 lb 3/5/2009 Consumer United States
Primary
Concomitant
Syncope Other Serious 2/28/2009 Male 220 lb 3/11/2009 Consumer United States
Primary
Concomitant
Syncope Other Serious 2/28/2009 Male 220 lb 3/16/2009 Physician United States
Primary
Concomitant
Sepsis Death 1/29/2009 Female 3/16/2009 Physician United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 1/20/2009 Female 3/17/2009 Physician United States
Primary
Concomitant
Death Death Female 199 lb 3/17/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization Male 140 lb 3/19/2009 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/28/2009 Female 231 lb 3/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death Female 199 lb 3/24/2009 Physician United States
Primary
Concomitant
Convulsion Hospitalization 3/15/2009 Female 160 lb 3/26/2009 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 11/24/2008 Male 180 lb 3/26/2009 Other Health Professional United States
Primary
Concomitant
Swelling Other Serious Female 175 lb 3/26/2009 Physician United States
Primary
Concomitant
Chest Discomfort Hospitalization 11/12/2008 Female 3/27/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/28/2009 72 Female 3/30/2009 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 11/24/2008 Male 180 lb 4/2/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Death Female 195 lb 4/8/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization Male 140 lb 4/8/2009 Physician United States
Primary
Concomitant
Syncope Hospitalization 2/28/2009 Male 220 lb 4/21/2009 Consumer United States
Primary
Concomitant
Pruritus Disability 10/15/2008 Female 108 lb 4/23/2009 Physician United States
Primary
Concomitant
Death Death 4/21/2009 Female 5/1/2009 Physician United States
Primary
Concomitant
Syncope Hospitalization 2/28/2009 Male 220 lb 5/5/2009 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization Female 5/13/2009 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 2/28/2009 Male 220 lb 5/13/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/24/2009 Female 5/13/2009 Consumer United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 4/7/2009 36 Male 5/14/2009 Physician United States
Primary
Concomitant
Pain Other Serious Female 139 lb 5/14/2009 Physician United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death 4/6/2009 Female 5/20/2009 Physician United States
Primary
Concomitant
Death Death 5/1/2009 Female 96 lb 5/20/2009 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization Female 5/21/2009 Physician United States
Primary
Concomitant
Pain Other Serious Female 139 lb 5/22/2009 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/28/2009 Female 231 lb 5/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Right Ventricular Failure Death 5/1/2009 Female 96 lb 5/29/2009 Physician United States
Primary
Concomitant
Right Ventricular Failure Other Serious 3/1/2009 Male 168 lb 5/29/2009 Physician United States
Primary
Concomitant
Syncope Hospitalization 2/28/2009 Male 220 lb 6/1/2009 Physician United States
Primary
Concomitant
Death Death Male 202 lb 6/3/2009 Consumer United States
Primary
Concomitant
Right Ventricular Failure Other Serious 3/1/2009 Male 168 lb 6/4/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/28/2009 72 Female 6/5/2009 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/1/2009 Male 168 lb 6/9/2009 Physician United States
Primary
Concomitant
Pleural Effusion Death Male 202 lb 6/12/2009 Physician United States
Primary
Concomitant
Death Death Female 250 lb 6/15/2009 Consumer United States
Primary
Concomitant
Right Ventricular Failure Life Threatening 4/24/2009 Female 6/24/2009 Physician United States
Primary
Concomitant
Cardiac Failure Death Female 250 lb 6/26/2009 Physician United States
Primary
Concomitant
Respiratory Arrest Hospitalization 3/15/2009 Female 160 lb 6/29/2009 Physician United States
Primary
Concomitant
Joint Swelling Other Serious Female 161 lb 6/30/2009 Physician United States
Primary
Concomitant
Nervous System Disorder Hospitalization 3/15/2009 Female 160 lb 7/7/2009 Physician United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 5/21/2009 Male 173 lb 7/13/2009 Physician United States
Primary
Concomitant
Death Death Male 156 lb 7/14/2009 Consumer United States
Primary
Concomitant
Subdural Haematoma Death 57 Male 7/15/2009 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 7/14/2009 Female 200 lb 7/28/2009 Other Health Professional United States
Primary
Concomitant
Death Hospitalization 7/21/2009 Female 159 lb 7/30/2009 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 5/21/2009 Male 173 lb 7/31/2009 Physician United States
Primary
Concomitant
Death Death Male 156 lb 8/4/2009 Physician United States
Primary
Concomitant
Death Death 7/16/2009 Male 312 lb 8/6/2009 Consumer United States
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization Female 8/18/2009 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization Female 161 lb 8/19/2009 Physician United States
Primary
Concomitant
Syncope Hospitalization 7/16/2009 Male 230 lb 8/19/2009 Physician United States
Primary
Concomitant
Death Death Male 8/24/2009 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 7/30/2009 Female 8/24/2009 Consumer United States
Primary
Secondary
Concomitant
Death Death Female 240 lb 8/25/2009 Consumer United States
Primary
Concomitant
Death Death 8/2/2009 Male 211 lb 8/26/2009 Consumer United States
Primary
Concomitant
Death Death 8/13/2009 Female 8/27/2009 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 7/30/2009 Female 8/28/2009 Physician United States
Primary
Secondary
Concomitant

Drug Data