Letairis combined with Metolazone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oedema Hospitalization 9/1/2007 Male 255 lb 9/28/2007 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious Female 250 lb 1/8/2008 Pharmacist United States
Primary
Concomitant
Death Death 12/16/2007 Male 1/29/2008 Physician United States
Primary
Concomitant
Oedema Peripheral 11/13/2007 Male 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/10/2007 Female 250 lb 4/30/2008 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 4/10/2008 Female 5/12/2008 Pharmacist United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 9/1/2007 Male 255 lb 7/1/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 9/1/2007 Male 255 lb 7/28/2008 Consumer United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 10/17/2007 Female 166 lb 7/30/2008 Pharmacist United States
Primary
Concomitant
Clostridium Difficile Colitis Other Serious 6/27/2008 Female 175 lb 8/4/2008 Physician United States
Primary
Concomitant
Arthralgia Other Serious 7/1/2008 Female 8/12/2008 Consumer United States
Primary
Concomitant
Dry Mouth Disability 8/5/2008 Female 8/21/2008 Consumer United States
Primary
Concomitant
Right Ventricular Failure Other Serious Female 150 lb 10/14/2008 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization Female 184 lb 11/7/2008 Other Health Professional United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 11/4/2008 Female 11/20/2008 Consumer United States
Primary
Concomitant
Syncope Other Serious Female 184 lb 12/10/2008 Consumer United States
Primary
Concomitant
Sickle Cell Anaemia Death Female 135 lb 12/17/2008 Physician United States
Primary
Concomitant
Death Death Male 225 lb 12/23/2008 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Death Male 225 lb 1/6/2009 Physician United States
Primary
Concomitant
Chest Pain Hospitalization Female 195 lb 3/3/2009 Other Health Professional United States
Primary
Concomitant
Death Death 1/8/2009 Male 162 lb 3/4/2009 Consumer United States
Primary
Concomitant
Syncope Other Serious 3/1/2008 Female 184 lb 3/5/2009 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization Female 195 lb 3/5/2009 Physician United States
Primary
Concomitant
Death Death 2/22/2009 Female 162 lb 3/5/2009 Consumer United States
Primary
Concomitant
Hypersensitivity Life Threatening Female 3/11/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Death Female 195 lb 4/8/2009 Physician United States
Primary
Concomitant
Death Death 4/7/2009 Female 190 lb 4/21/2009 Consumer United States
Primary
Concomitant
Sudden Death Death 4/7/2009 Female 190 lb 5/4/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization Male 366 lb 5/6/2009 Physician United States
Primary
Concomitant
Gout Hospitalization 4/21/2009 Female 5/14/2009 Consumer United States
Primary
Concomitant
Gout Hospitalization 4/21/2009 Female 5/21/2009 Physician United States
Primary
Concomitant
Hypertension Other Serious Male 210 lb 5/22/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Death Female 158 lb 6/2/2009 Other Health Professional United States
Primary
Concomitant
Liver Disorder Other Serious Female 111 lb 6/15/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/6/2009 Male 222 lb 6/19/2009 Physician United States
Primary
Concomitant
Death Death 5/29/2009 Female 140 lb 6/26/2009 Consumer United States
Primary
Concomitant
Death Death 6/22/2009 Male 134 lb 6/29/2009 Consumer United States
Primary
Concomitant
Renal Failure Chronic Hospitalization Male 217 lb 6/30/2009 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization Female 123 lb 7/6/2009 Physician United States
Primary
Concomitant
Death Death Female 119 lb 7/8/2009 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization Female 123 lb 7/13/2009 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization Female 123 lb 7/14/2009 Physician United States
Primary
Concomitant
Death Death 6/27/2009 Male 172 lb 7/15/2009 Other Health Professional United States
Primary
Concomitant
Fluid Retention Hospitalization 7/11/2009 Female 7/22/2009 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Death 6/27/2009 Male 172 lb 7/22/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death Female 140 lb 7/23/2009 Physician United States
Primary
Concomitant
Intestinal Haemorrhage Hospitalization Female 260 lb 8/4/2009 Consumer United States
Primary
Concomitant
Death Death 7/16/2009 Male 312 lb 8/6/2009 Consumer United States
Primary
Concomitant
Renal Failure Death Male 312 lb 8/31/2009 Physician United States
Primary
Concomitant
Death Death Female 279 lb 9/2/2009 Consumer United States
Primary
Concomitant
Haemorrhage Hospitalization Female 260 lb 9/16/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization Female 241 lb 9/23/2009 Physician United States
Primary
Concomitant
Death Death 10/1/2009 Female 10/12/2009 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Death 10/3/2009 Female 10/15/2009 Physician United States
Primary
Concomitant
Sepsis Hospitalization 9/16/2009 Female 12/9/2009 Physician United States
Primary
Concomitant
Transfusion Hospitalization 11/18/2009 Female 12/14/2009 Consumer United States
Primary
Concomitant
Death Death 12/10/2009 Female 139 lb 12/15/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Death Female 139 lb 12/18/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 11/18/2009 Female 12/23/2009 Physician United States
Primary
Concomitant
Death Death Female 1/5/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization Female 2/4/2010 Physician United States
Primary
Concomitant
Presyncope Hospitalization Female 98 lb 2/5/2010 Consumer United States
Primary
Concomitant
Syncope Hospitalization Female 220 lb 2/19/2010 Consumer United States
Primary
Concomitant
Syncope Hospitalization Female 220 lb 3/4/2010 Physician United States
Primary
Concomitant
Palpitations Disability 1/18/2010 Female 155 lb 3/19/2010 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 3/5/2010 Male 260 lb 3/26/2010 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 3/20/2010 Male 168 lb 3/30/2010 Consumer United States
Primary
Concomitant
Death Death Male 195 lb 4/2/2010 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 3/20/2010 89 Male 168 lb 4/6/2010 Physician United States
Primary
Concomitant
Respiratory Failure Death Male 195 lb 4/12/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization Female 259 lb 4/13/2010 Physician United States
Primary
Concomitant
Abdominal Distension Hospitalization Female 5/3/2010 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 4/7/2010 62 Male 271 lb 5/5/2010 Consumer United States
Primary
Concomitant
Pain Hospitalization Female 5/6/2010 Physician United States
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization Female 5/12/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 12/18/2008 58 Female 183 lb 5/27/2010 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 3/20/2010 89 Male 168 lb 6/3/2010 Physician United States
Primary
Concomitant
Death Death 4/29/2010 79 Male 6/9/2010 Consumer United States
Primary
Concomitant
Haemorrhage Hospitalization 6/2/2010 78 Male 230 lb 6/11/2010 Consumer United States
Primary
Concomitant
Death Death Female 6/11/2010 Consumer United States
Primary
Concomitant
Lymphoedema Hospitalization 5/1/2010 65 Male 150 lb 6/11/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 5/29/2010 62 Male 165 lb 6/14/2010 Consumer United States
Primary
Concomitant
Haemorrhage Hospitalization 6/2/2010 78 Male 230 lb 6/16/2010 Physician United States
Primary
Concomitant
Respiratory Failure Death Female 6/21/2010 Physician United States
Primary
Concomitant
Death Death Male 6/30/2010 Consumer United States
Primary
Concomitant
Drug Intolerance Hospitalization Female 236 lb 7/2/2010 Consumer United States
Primary
Concomitant
Cardiac Failure Death Female 7/6/2010 Other Health Professional United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death Male 7/9/2010 Physician United States
Primary
Concomitant
Liver Disorder Hospitalization Female 198 lb 7/9/2010 Consumer United States
Primary
Concomitant
Fluid Overload Hospitalization Female 236 lb 7/15/2010 Physician United States
Primary
Concomitant
Respiratory Failure Death 4/29/2010 79 Male 7/20/2010 Other Health Professional United States
Primary
Concomitant
Liver Disorder Hospitalization Female 198 lb 7/21/2010 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization Male 7/21/2010 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization Male 7/28/2010 Physician United States
Primary
Concomitant
Liver Disorder Hospitalization Female 198 lb 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 66 Female 187 lb 9/14/2010 Consumer United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death Female 187 lb 9/20/2010 Consumer United States
Primary
Concomitant
Death Death Male 171 lb 9/21/2010 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Death 9/5/2010 49 Female 9/17/2010 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization Female 9/23/2010 Physician United States
Primary
Concomitant
Death Death Male 9/24/2010 Consumer United States
Primary
Concomitant
Collapse Of Lung Hospitalization 70 Male 157 lb 9/28/2010 Consumer United States
Primary
Concomitant
Death Death Male 145 lb 9/28/2010 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization Female 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious Male 171 lb 9/30/2010 Consumer United States
Primary
Concomitant
Death Death 9/23/2010 79 Male 205 lb 10/5/2010 Other Health Professional United States
Primary
Concomitant
Blood Test Abnormal Hospitalization Female 129 lb 10/6/2010 Consumer United States
Primary
Concomitant
Renal Failure Death Male 145 lb 10/12/2010 Physician United States
Primary
Concomitant
Gastric Disorder Hospitalization 42 Female 174 lb 10/15/2010 Consumer United States
Primary
Concomitant
Death Death Male 10/18/2010 Physician United States
Primary
Concomitant
Respiratory Failure Death 9/21/2010 83 Male 10/20/2010 Consumer United States
Primary
Concomitant
Death Death Female 183 lb 10/20/2010 Consumer United States
Primary
Concomitant
Generalised Oedema Hospitalization Male 240 lb 10/20/2010 Physician United States
Primary
Concomitant
Fluid Overload Hospitalization 8/16/2010 71 Male 10/22/2010 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening Male 10/26/2010 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization Male 10/27/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 80 Female 200 lb 10/28/2010 Consumer United States
Primary
Concomitant
Presyncope Hospitalization Female 160 lb 10/28/2010 Consumer United States
Primary
Concomitant
Death Death Female 183 lb 11/1/2010 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening Male 11/11/2010 Physician United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization Male 11/15/2010 Consumer United States
Primary
Concomitant
Sepsis Hospitalization Female 11/16/2010 Consumer United States
Primary
Concomitant
Transaminases Increased Hospitalization Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization Female 12/14/2010 Physician United States
Primary
Concomitant
Right Ventricular Failure Death Male 3/16/2011 Other Health Professional United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 12/18/2010 71 Female 3/30/2011 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 8/19/2010 51 Female 332 lb 3/30/2011 Physician United States
Primary
Concomitant
Hypokalaemia Hospitalization 3/27/2011 49 Female 5/9/2011 Physician United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/25/2011 73 Female 5/17/2011 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 4/12/2011 40 Female 174 lb 6/24/2011 Physician United States
Primary
Concomitant
Death Death Male 245 lb 6/29/2011 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 6/21/2011 37 Male 7/15/2011 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 10/3/2011 Physician United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 8/18/2011 54 Male 187 lb 10/13/2011 Physician United States
Primary
Concomitant
Disease Progression Death Male 11/7/2011 Other Health Professional United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 11/17/2011 36 Female 12/12/2011 Physician United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 11/17/2011 36 Female 167 lb 12/20/2011 Physician United States
Primary
Secondary
Concomitant
Fluid Retention 4/1/2011 58 Male 2/29/2012 Consumer United States
Primary
Concomitant
Blood Potassium Decreased Hospitalization Female 3/6/2012 Consumer United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 11/17/2011 36 Female 3/15/2012 Physician United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 11/17/2011 36 Female 4/17/2012 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 37 Male 6/15/2012 Physician United States
Primary
Concomitant
Oedema 5/17/2012 37 Male 6/12/2012 Pharmacist United States
Primary
Concomitant
Condition Aggravated 5/17/2012 37 Male 6/12/2012 Pharmacist United States
Primary
Concomitant
Abdominal Discomfort Hospitalization 5/10/2012 6/29/2012 Pharmacist United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 5/10/2012 7/19/2012 Physician United States
Primary
Concomitant
Right Ventricular Failure Hospitalization Female 8/21/2012 Consumer United States
Primary
Concomitant
Drug Interaction Other Serious 11/17/2011 36 Female 168 lb 11/9/2012 Physician Us
Primary
Concomitant
Interacting
Right Ventricular Failure Hospitalization 7/2012 Male 12/4/2012 Consumer Us
Primary
Concomitant
Syncope Hospitalization Female 12/27/2012 Consumer Us
Primary
Concomitant

Drug Data