Letairis combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Oedema Hospitalization 6/8/2008 Male 265 lb 6/30/2008 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Hospitalization Female 220 lb 10/15/2008 Physician United States
Primary
Concomitant
Photopsia Other Serious Male 160 lb 10/16/2008 Consumer United States
Primary
Concomitant
Renal Failure Death 1/1/2009 Female 1/22/2009 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/29/2009 Female 222 lb 2/5/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Death 2/6/2009 Male 270 lb 3/4/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening 9/22/2008 Male 194 lb 3/24/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization Female 132 lb 3/26/2009 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2009 Male 3/27/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 5/6/2009 65 Male 6/10/2009 Physician United States
Primary
Secondary
Concomitant
Nasal Congestion Other Serious Male 210 lb 7/7/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization Female 210 lb 7/29/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization Female 210 lb 8/7/2009 Physician United States
Primary
Concomitant
Oxygen Saturation Decreased Other Serious Female 8/18/2009 Physician United States
Primary
Concomitant
Organising Pneumonia Life Threatening Female 10/7/2009 Physician United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 5/22/2009 Male 165 lb 10/20/2009 Physician United States
Primary
Concomitant
Death Death 9/25/2009 Female 10/20/2009 Consumer United States
Primary
Concomitant
Angina Pectoris Hospitalization Male 190 lb 10/21/2009 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Hospitalization Male 1/4/2010 Consumer United States
Primary
Concomitant
Idiopathic Pulmonary Fibrosis Hospitalization Male 1/8/2010 Physician United States
Primary
Concomitant
Blood Pressure Increased Hospitalization Female 1/28/2010 Pharmacist United States
Primary
Concomitant
Cardiac Failure Congestive Death Male 191 lb 2/3/2010 Other Health Professional United States
Primary
Concomitant
Death Death Male 2/3/2010 Consumer United States
Primary
Concomitant
Death Death Male 190 lb 2/15/2010 Consumer United States
Primary
Concomitant
Coronary Artery Bypass Hospitalization Female 127 lb 2/22/2010 Consumer United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death 2/2/2010 Male 2/22/2010 Consumer United States
Primary
Concomitant
Pulmonary Arterial Pressure Increased Other Serious Female 122 lb 2/23/2010 Consumer United States
Primary
Concomitant
Back Pain Hospitalization Female 138 lb 2/24/2010 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization Female 163 lb 4/5/2010 Other Health Professional United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 4/15/2010 68 Female 4/26/2010 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Death Female 163 lb 4/29/2010 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Death Male 190 lb 5/6/2010 Physician United States
Primary
Concomitant
Death Death 5/19/2010 82 Female 6/7/2010 Consumer United States
Primary
Concomitant
Pain Life Threatening 2/15/2010 68 Female 6/16/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/5/2010 74 Female 6/17/2010 Other Health Professional United States
Primary
Concomitant
Septic Shock Hospitalization Female 6/22/2010 Physician United States
Primary
Concomitant
Death Death 6/13/2010 54 Female 35 lb 6/22/2010 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Hospitalization 5/16/2010 70 Female 7/12/2010 Consumer United States
Primary
Concomitant
Death Death 6/9/2010 51 Female 264 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization Male 210 lb 8/24/2010 Consumer United States
Primary
Concomitant
Death Death 8/20/2010 73 Female 105 lb 9/1/2010 Consumer United States
Primary
Concomitant
Lung Cancer Metastatic Death Female 163 lb 9/9/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Hospitalization 7/4/2010 77 Female 9/21/2010 Physician United States
Primary
Concomitant
Haemorrhage Intracranial Death Female 105 lb 9/22/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization Female 9/23/2010 Physician United States
Primary
Concomitant
Lung Transplant Hospitalization 59 Male 195 lb 9/28/2010 Consumer United States
Primary
Concomitant
Death Death 9/23/2010 79 Male 205 lb 10/5/2010 Other Health Professional United States
Primary
Concomitant
Septic Shock Hospitalization Male 240 lb 10/5/2010 Physician United States
Primary
Concomitant
Catheterisation Cardiac Hospitalization Female 235 lb 10/6/2010 Physician United States
Primary
Concomitant
Death Death 9/20/2010 77 Male 172 lb 10/14/2010 Consumer United States
Primary
Concomitant
Adverse Drug Reaction Hospitalization 78 Female 155 lb 10/25/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening 9/8/2010 56 Female 315 lb 10/25/2010 Physician United States
Primary
Concomitant
Lung Transplant Hospitalization 59 Male 195 lb 10/26/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 10/18/2010 43 Female 10/29/2010 Physician United States
Primary
Concomitant
Malaise Hospitalization 78 Female 155 lb 11/24/2010 Physician United States
Primary
Concomitant
Malaise Hospitalization 78 Female 155 lb 12/22/2010 Physician United States
Primary
Concomitant
Hypoxic-ischaemic Encephalopathy Hospitalization Female 260 lb 12/23/2010 Other Health Professional United States
Primary
Concomitant
Back Pain Hospitalization 78 Female 155 lb 1/10/2011 Physician United States
Primary
Concomitant
Pulmonary Fibrosis Death Female 1/12/2011 Physician United States
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 1/9/2011 59 Female 2/3/2011 Physician United States
Primary
Concomitant
Hepatic Cirrhosis 1/25/2011 59 Female 1/28/2011 Pharmacist United States
Primary
Concomitant
Respiratory Failure Death Male 172 lb 2/9/2011 Physician United States
Primary
Concomitant
Dyspnoea Death 10/1/2010 85 Female 110 lb 2/23/2011 Physician United States
Primary
Concomitant
Ankle Fracture Other Serious Female 3/22/2011 Physician United States
Primary
Concomitant
Femur Fracture Hospitalization 12/3/2010 63 Female 387 lb 3/30/2011 Physician United States
Primary
Concomitant
Death Death Female 240 lb 4/14/2011 Other Health Professional United States
Primary
Concomitant
Non-alcoholic Steatohepatitis Other Serious 2/23/2012 69 Male 8/9/2012 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 8/2012 62 Male 6/14/2013 Physician Us
Primary
Secondary
Concomitant
Palpitations 11/23/2012 46 Female 11/26/2012 Pharmacist Us
Primary
Concomitant
Weight Increased Other Serious Female 2/13/2013 Physician Us
Primary
Concomitant
Death Death Male 1/29/2013 Consumer Us
Primary
Concomitant
Sepsis Death Female 3/6/2013 Consumer Us
Primary
Concomitant
Respiratory Failure Death 3/3/2013 82 Female 3/13/2013 Pharmacist Us
Primary
Concomitant
Respiratory Failure Hospitalization 2/26/2013 82 Female 6/17/2013 Physician Us
Primary
Concomitant
Unevaluable Event Life Threatening Male 3/21/2013 Consumer Us
Primary
Concomitant
Vomiting Other Serious 6/17/2011 37 Female 8/22/2013 Physician Us
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 2006 Male 240 lb 5/16/2013 Consumer Us
Primary
Concomitant
Syncope Hospitalization 8/5/2013 76 Male 8/15/2013 Consumer Us
Primary
Concomitant
Troponin Increased Death 9/19/2013 55 Male 10/1/2013 Physician Us
Primary
Concomitant
Urinary Retention Other Serious 9/2013 51 Female 10/11/2013 Consumer Us
Primary
Concomitant
Ulcer Haemorrhage Hospitalization 10/1/2013 64 Female 11/18/2013 Other Health Professional Us
Primary
Concomitant
Oedema Peripheral Other Serious 11/12/2013 70 Female 174 lb 11/15/2013 Other Health Professional Us
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 9/11/2007 53 Male 11/18/2013 Consumer Us
Primary
Concomitant
Oedema Peripheral Male 11/19/2013 Other Health Professional Us
Primary
Concomitant
Oedema Peripheral Other Serious Female 11/20/2013 Physician Us
Primary
Concomitant
Overdose 12/20/2007 75 Female 155 lb 11/20/2013 Other Health Professional Us
Primary
Concomitant
Palpitations 1/5/2008 60 Female 151 lb 11/20/2013 Other Health Professional Us
Primary
Concomitant
Insomnia Male 220 lb 11/20/2013 Pharmacist Us
Primary
Concomitant
Nasal Congestion 2/10/2008 49 Female 172 lb 11/20/2013 Other Health Professional Us
Primary
Concomitant
Nasal Congestion Female 310 lb 11/20/2013 Physician Us
Primary
Concomitant
Nausea Female 195 lb 11/20/2013 Pharmacist Us
Primary
Concomitant
Respiratory Gas Exchange Disorder Male 212 lb 11/20/2013 Pharmacist Us
Primary
Concomitant
Local Swelling 2/10/2008 75 Male 194 lb 11/20/2013 Other Health Professional Us
Primary
Concomitant
Oedema Peripheral 3/1/2008 67 Male 250 lb 11/21/2013 Other Health Professional Us
Primary
Concomitant
Nasal Congestion Female 132 lb 11/21/2013 Pharmacist Us
Primary
Concomitant
Tremor 3/28/2008 71 Female 11/21/2013 Pharmacist Us
Primary
Concomitant
Tremor Female 180 lb 11/21/2013 Pharmacist Us
Primary
Concomitant
Palpitations Female 325 lb 11/21/2013 Pharmacist Us
Primary
Concomitant
Haemoglobin Decreased 3/28/2008 81 Male 147 lb 11/21/2013 Pharmacist Us
Primary
Concomitant
Nasal Congestion 4/21/2008 57 Female 245 lb 11/21/2013 Other Health Professional Us
Primary
Concomitant
Dyspnoea Male 220 lb 11/21/2013 Pharmacist Us
Primary
Concomitant
Oedema Peripheral 5/29/2008 78 Female 11/21/2013 Pharmacist Us
Primary
Concomitant
Blood Glucose Abnormal 5/2008 47 Female 11/21/2013 Pharmacist Us
Primary
Concomitant
Weight Increased Female 136 lb 11/22/2013 Pharmacist Us
Primary
Concomitant
Oedema Peripheral Female 11/22/2013 Pharmacist Us
Primary
Concomitant
Liver Function Test Abnormal Female 179 lb 11/22/2013 Pharmacist Us
Primary
Concomitant
Constipation Male 240 lb 11/22/2013 Pharmacist Us
Primary
Concomitant
Oedema Peripheral Female 11/22/2013 Pharmacist Us
Primary
Concomitant
Joint Swelling Male 174 lb 11/22/2013 Pharmacist Us
Primary
Concomitant
Oedema Peripheral Female 11/22/2013 Pharmacist Us
Primary
Concomitant
Gait Disturbance Male 375 lb 11/22/2013 Pharmacist Us
Primary
Concomitant
Drug Hypersensitivity Female 175 lb 11/26/2013 Pharmacist Us
Primary
Concomitant
Dyspnoea 9/21/2008 73 Female 11/26/2013 Pharmacist Us
Primary
Concomitant
Fluid Overload Other Serious 7/31/2008 59 Male 208 lb 11/26/2013 Other Health Professional Us
Primary
Concomitant
Nasal Congestion Female 240 lb 11/26/2013 Pharmacist Us
Primary
Concomitant
Oedema Peripheral Female 11/26/2013 Pharmacist Us
Primary
Concomitant
Oedema Peripheral Female 175 lb 11/26/2013 Pharmacist Us
Primary
Concomitant
Swelling Female 195 lb 11/26/2013 Pharmacist Us
Primary
Concomitant
Local Swelling Female 235 lb 11/26/2013 Pharmacist Us
Primary
Concomitant
Anaemia Female 175 lb 11/26/2013 Pharmacist Us
Primary
Concomitant
Oedema Peripheral Disability 11/12/2008 53 Male 230 lb 11/26/2013 Physician Us
Primary
Concomitant
Palpitations Male 11/26/2013 Pharmacist Us
Primary
Concomitant
Gingival Swelling Female 168 lb 11/27/2013 Pharmacist Us
Primary
Concomitant
Swelling Face Female 144 lb 11/27/2013 Physician Us
Primary
Concomitant
Palpitations 1/17/2009 62 Male 157 lb 11/27/2013 Other Health Professional Us
Primary
Concomitant
Pruritus Female 190 lb 11/27/2013 Pharmacist Us
Primary
Concomitant
Weight Increased 12/1/2008 72 Male 11/27/2013 Pharmacist Us
Primary
Concomitant
Diarrhoea 10/6/2007 68 Female 215 lb 11/27/2013 Other Health Professional Us
Primary
Concomitant
Heart Rate Increased Female 235 lb 11/27/2013 Pharmacist Us
Primary
Concomitant
Oedema Peripheral Female 235 lb 11/27/2013 Pharmacist Us
Primary
Concomitant
Dyspnoea Hospitalization Female 222 lb 12/4/2013 Pharmacist Us
Primary
Concomitant
Swelling Face Female 147 lb 12/4/2013 Pharmacist Us
Primary
Concomitant
Pain In Extremity 4/10/2009 77 Female 205 lb 12/4/2013 Other Health Professional Us
Primary
Concomitant
Oedema Peripheral Female 260 lb 12/4/2013 Pharmacist Us
Primary
Concomitant
Hypersensitivity Male 12/4/2013 Pharmacist Us
Primary
Concomitant
Weight Increased Life Threatening Female 12/4/2013 Physician Us
Primary
Concomitant
Weight Increased Male 230 lb 12/4/2013 Pharmacist Us
Primary
Concomitant
Oedema Peripheral 5/15/2009 73 Female 12/4/2013 Pharmacist Us
Primary
Concomitant
Sinusitis Female 200 lb 12/4/2013 Pharmacist Us
Primary
Concomitant
Swelling Female 173 lb 12/4/2013 Other Health Professional Us
Primary
Concomitant
Thrombocytopenia 4/6/2009 61 Female 12/4/2013 Pharmacist Us
Primary
Concomitant
Presyncope Male 154 lb 12/4/2013 Pharmacist Us
Primary
Concomitant
Rhinorrhoea Female 240 lb 12/6/2013 Pharmacist Us
Primary
Concomitant
Local Swelling Female 215 lb 12/6/2013 Pharmacist Us
Primary
Concomitant
Palpitations 6/15/2009 69 Female 12/6/2013 Pharmacist Us
Primary
Concomitant
Oedema Peripheral 5/1/2009 67 Male 12/6/2013 Pharmacist Us
Primary
Concomitant
Hypotension Male 226 lb 12/6/2013 Pharmacist Us
Primary
Concomitant
Headache Female 147 lb 12/6/2013 Pharmacist Us
Primary
Concomitant
Swelling Female 12/6/2013 Other Health Professional Us
Primary
Concomitant
Nasal Congestion Female 165 lb 12/6/2013 Pharmacist Us
Primary
Concomitant

Drug Data