Leflunomide combined with Tramadol Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Arthritis Bacterial Hospitalization 11/28/2005 Female 3/9/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization Male 4/21/2006 Physician Belgium
Primary
Concomitant
Rheumatoid Arthritis Hospitalization Male 4/26/2006 Physician Belgium
Primary
Concomitant
Pulmonary Tuberculosis Death 7/6/2004 Male 126 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Lesion 8/15/2005 Male 148 lb 8/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization Male 8/7/2006 Physician Belgium
Primary
Concomitant
Knee Arthroplasty Hospitalization 1/24/2006 Female 203 lb 8/25/2006 Physician Germany
Primary
Concomitant
Tachycardia Other Serious 7/24/2006 Female 106 lb 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Wegener's Granulomatosis Hospitalization 11/3/2005 Female 9/21/2006 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 6/24/2005 Female 148 lb 9/27/2006 Consumer United Kingdom
Primary
Concomitant
Cerebral Infarction Other Serious Male 170 lb 10/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 9/24/2004 45 Female 168 lb 11/21/2006 France
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 4/15/2006 Female 143 lb 12/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Convulsion Hospitalization 10/15/2006 Male 141 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Death Female 128 lb 1/22/2007 France
Primary
Concomitant
Joint Dislocation Hospitalization 8/23/2004 Female 152 lb 1/24/2007 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Death 1/1/2005 Female 95 lb 1/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 Female 1/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Wegener's Granulomatosis Other Serious 2/24/2005 Female 2/6/2007 Physician Germany
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/2/2007 Female 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Infarction Death 11/13/2006 Female 128 lb 2/16/2007 France
Primary
Concomitant
Urinary Tract Infection Other Serious 11/16/2006 Female 123 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 8/15/2006 Male 223 lb 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 Female 6/4/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 6/1/2006 82 Female 190 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious 9/1/2004 Female 238 lb 7/5/2007 Consumer United Kingdom
Primary
Concomitant
Smear Cervix Abnormal Hospitalization 1/1/2007 Female 108 lb 7/11/2007 Consumer United States
Primary
Concomitant
Weight Decreased Death 1/1/2005 Female 95 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Smear Cervix Abnormal Hospitalization 1/1/2007 Female 108 lb 8/3/2007 Consumer United States
Primary
Concomitant
Intervertebral Disc Compression Hospitalization 7/1/2007 Female 128 lb 8/30/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/10/2007 Female 335 lb 10/19/2007 United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2007 76 Female 197 lb 10/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/4/2007 Female 11/1/2007 Belgium
Primary
Concomitant
Staphylococcal Infection Other Serious 9/19/2006 Male 11/28/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Viral Infection Hospitalization 12/20/2006 Male 146 lb 12/7/2007 United Kingdom
Primary
Concomitant
Urosepsis Life Threatening 6/10/2007 Female 335 lb 12/7/2007 United Kingdom
Primary
Concomitant
Furuncle 6/1/2007 Female 120 lb 12/14/2007 Consumer United States
Primary
Concomitant
Flatulence 10/24/2007 Male 148 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 12/19/2007 Germany
Primary
Concomitant
Interstitial Lung Disease Death 9/23/2007 80 1/16/2008
Primary
Concomitant
Dyspnoea Life Threatening 11/7/2007 Male 251 lb 2/29/2008 United Kingdom
Primary
Concomitant
Vomiting 1/14/2008 Female 183 lb 3/15/2008 United States
Primary
Concomitant
Injection Site Urticaria 1/31/2008 Female 124 lb 3/15/2008 United States
Primary
Concomitant
Vomiting 2/15/2008 Female 205 lb 3/15/2008 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 3/17/2008 Male 3/28/2008 Belgium
Primary
Concomitant
Peripheral Embolism Life Threatening 11/7/2007 Male 251 lb 4/4/2008 United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 9/23/2007 80 4/4/2008
Primary
Concomitant
Tachycardia Hospitalization 3/17/2008 Male 4/22/2008 Belgium
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/29/2007 Female 187 lb 4/25/2008 United Kingdom
Primary
Concomitant
Circulating Anticoagulant Life Threatening 3/1/2008 Female 137 lb 5/2/2008 Physician France
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/4/2007 Female 5/2/2008 Belgium
Primary
Concomitant
Benign Respiratory Tract Neoplasm Hospitalization 5/2/2008 48 Male 5/16/2008 Other Health Professional Sweden
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 5/2/2008 48 Male 5/23/2008 Other Health Professional Sweden
Primary
Concomitant
Skin Burning Sensation 1/1/2007 Male 190 lb 6/11/2008 United States
Primary
Concomitant
Arthralgia 2/1/2008 Female 6/12/2008 United States
Primary
Concomitant
Injection Site Pruritus 5/27/2008 Male 185 lb 6/13/2008 United States
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 49 Female 6/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/15/2007 Female 187 lb 7/11/2008 United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/2/2008 49 Female 7/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Cancer Other Serious 6/19/2006 Male 161 lb 7/21/2008 United Kingdom
Primary
Concomitant
Gastrointestinal Surgery Hospitalization 3/31/2008 Female 181 lb 7/23/2008 United Kingdom
Primary
Concomitant
Meningitis Tuberculous Hospitalization 11/8/2006 Female 170 lb 8/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rhinitis Allergic Other Serious 12/1/2007 Male 8/7/2008 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Death Female 146 lb 8/7/2008 United Kingdom
Primary
Concomitant
Temporal Arteritis Death Female 123 lb 8/12/2008 United Kingdom
Primary
Concomitant
Autoimmune Neutropenia Hospitalization 1/1/2001 56 Female 8/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Autoimmune Neutropenia Hospitalization 1/1/2001 56 Female 8/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 8/1/2006 Female 164 lb 9/5/2008 Consumer United States
Primary
Concomitant
Skin Burning Sensation 1/1/2007 Male 190 lb 9/12/2008 United States
Primary
Concomitant
Nasopharyngitis 7/30/2008 Female 225 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 9/18/2008 Germany
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 49 Female 10/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Death Female 146 lb 10/3/2008 United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 7/10/2008 Male 161 lb 10/6/2008 United Kingdom
Primary
Concomitant
Death Other Serious Male 152 lb 10/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Polydipsia Other Serious 6/1/2008 58 Female 10/20/2008 Physician Colombia
Primary
Concomitant
Polydipsia Other Serious 6/1/2008 58 Female 10/22/2008 Physician Colombia
Primary
Concomitant
Polydipsia Other Serious 6/1/2008 58 Female 115 lb 10/31/2008 Physician Colombia
Primary
Concomitant
Polydipsia Other Serious 6/1/2008 58 Female 115 lb 11/17/2008 Physician Colombia
Primary
Concomitant
Nerve Compression Hospitalization 11/4/2004 Female 176 lb 12/2/2008 United Kingdom
Primary
Concomitant
Wheezing 7/1/2008 Female 217 lb 12/12/2008 Physician United States
Primary
Concomitant
Psoriasis 10/16/2008 Female 12/12/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 10/1/2008 Male 152 lb 1/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Erythema Multiforme Disability 52 Female 154 lb 1/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 10/24/2008 Female 2/10/2009 United Kingdom
Primary
Concomitant
Sepsis Death 10/24/2008 Female 2/16/2009 United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 1/9/2008 Male 2/16/2009 United Kingdom
Primary
Concomitant
Injection Site Swelling Other Serious 12/1/2008 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Other Serious 9/15/2004 Female 134 lb 3/26/2009 Germany
Primary
Concomitant
Hypertension Other Serious 9/15/2004 Female 134 lb 3/27/2009 Germany
Primary
Concomitant
Hypertension Hospitalization 9/15/2004 Female 134 lb 4/14/2009 Germany
Primary
Concomitant
Vomiting Hospitalization 2/28/2009 64 Male 5/4/2009 Consumer Colombia
Primary
Concomitant
Osteonecrosis Other Serious 7/10/2008 Male 161 lb 5/11/2009
Primary
Concomitant
Respiratory Tract Infection Hospitalization 3/5/2009 67 Female 5/20/2009 Other Health Professional Spain
Primary
Concomitant
Interacting
Respiratory Tract Infection Hospitalization 3/5/2009 67 Female 5/21/2009 Physician Spain
Primary
Concomitant
Interacting
Respiratory Tract Infection Hospitalization 3/5/2009 67 Female 5/26/2009 Other Health Professional Spain
Primary
Concomitant
Interacting
Lymph Node Cancer Metastatic Other Serious 4/2/2009 Male 6/5/2009 United Kingdom
Primary
Concomitant
Hypertension Hospitalization 9/15/2004 Female 134 lb 6/5/2009 Germany
Primary
Concomitant
Respiratory Tract Infection Hospitalization 3/5/2009 67 Female 6/8/2009 Physician Spain
Primary
Concomitant
Interacting
Respiratory Tract Infection Hospitalization 3/5/2009 67 Female 6/8/2009 Other Health Professional Spain
Primary
Concomitant
Interacting
Non-small Cell Lung Cancer Metastatic Other Serious 4/2/2009 Male 6/11/2009 United Kingdom
Primary
Concomitant
Weight Decreased 10/24/2007 64 Male 148 lb 6/18/2009 United States
Primary
Secondary
Concomitant
Bursitis Other Serious Male 194 lb 8/21/2009 Brazil
Primary
Secondary
Concomitant
Incorrect Dose Administered 3/5/2007 Female 224 lb 9/11/2009 Consumer United States
Primary
Concomitant
Tongue Ulceration Other Serious 6/5/2009 69 Female 132 lb 9/18/2009 Consumer United States
Primary
Concomitant
Splenomegaly Life Threatening 7/1/2009 Female 178 lb 10/29/2009 Physician United States
Primary
Concomitant
Pneumonia Death Female 121 lb 11/10/2009 United Kingdom
Primary
Concomitant
Skin Cancer Other Serious 10/1/2007 Female 159 lb 11/24/2009 Consumer United Kingdom
Primary
Concomitant
Throat Tightness 1/1/2006 Female 12/1/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/28/2009 64 Male 12/1/2009 Consumer Colombia
Primary
Concomitant
Skin Cancer Other Serious Female 159 lb 11/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 7/1/2009 57 Female 178 lb 12/9/2009 Other Health Professional United States
Primary
Concomitant
Headache Other Serious 4/1/2009 39 Female 12/22/2009 Physician United Kingdom
Primary
Concomitant
Throat Irritation 9/17/2009 Female 182 lb 1/29/2010 United States
Primary
Concomitant
Nasopharyngitis Other Serious 9/1/2009 Male 296 lb 2/3/2010 United States
Primary
Concomitant
Chest Pain 68 Female 154 lb 2/22/2010 Other Health Professional United States
Primary
Concomitant
Headache 1/1/2009 55 Female 1/28/2010 Consumer United States
Primary
Concomitant
Skin Cancer Other Serious 10/1/2007 58 Female 159 lb 3/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Poor Quality Drug Administered Other Serious 1/1/2009 57 Male 235 lb 5/13/2010 United States
Primary
Concomitant
Peripheral Vascular Disorder Hospitalization 10/17/2009 59 Male 171 lb 6/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Endometrial Cancer Recurrent Life Threatening 5/29/2009 57 Female 201 lb 8/2/2010 Physician United States
Primary
Concomitant
Osteomyelitis Other Serious 7/27/2010 58 Female 150 lb 8/5/2010 Physician Canada
Primary
Concomitant
Oedema Peripheral Other Serious Male 8/19/2010 Consumer Germany
Primary
Concomitant
Sinusitis Other Serious 8/1/2009 51 Female 9/10/2010 Other Health Professional South Africa
Primary
Concomitant
Sepsis Death 6/5/2010 68 Female 11/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 11/14/2010 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 11/22/2010 Physician South Africa
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 11/24/2010 Physician South Africa
Primary
Concomitant
Pneumonia Hospitalization 11/4/2010 63 Male 158 lb 11/24/2010 Physician South Africa
Primary
Concomitant
Injection Site Pruritus 9/1/2009 12/19/2010 Consumer United States
Primary
Concomitant
Rash Pruritic 9/1/2009 12/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Hospitalization 11/17/2010 54 Female 12/27/2010 Pharmacist Colombia
Primary
Concomitant
Wheezing Disability 12/20/2010 64 Male 225 lb 1/6/2011 Physician United Kingdom
Primary
Concomitant
Injection Site Pain 8/6/2010 60 Female 1/29/2011 Consumer United States
Primary
Concomitant
Fatigue 2/1/2010 42 Female 1/29/2011 Consumer United States
Primary
Concomitant
Muscular Weakness 9/1/2010 60 Female 1/30/2011 Consumer United States
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/22/2009 67 Female 99 lb 4/21/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Endometrial Cancer Metastatic Hospitalization 5/29/2009 57 Female 201 lb 5/26/2011 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 5/3/2011 82 Female 6/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 2/24/2011 82 Female 6/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Hospitalization 5/27/2011 62 Male 7/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 5/27/2011 62 Male 166 lb 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/22/2009 67 Female 99 lb 7/6/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Bone Marrow Toxicity Hospitalization 5/27/2011 62 Male 166 lb 6/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 5/27/2011 62 Male 7/1/2011 United Kingdom
Primary
Concomitant
Pancytopenia Hospitalization 5/27/2011 62 Male 166 lb 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 5/27/2011 62 Male 166 lb 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 5/27/2011 62 Male 166 lb 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data