Leflunomide combined with Ramipril

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Radiation Oesophagitis Hospitalization 5/1/2005 Male 4/5/2006 Physician Germany
Primary
Concomitant
Nodule Other Serious 4/3/2005 Female 170 lb 5/5/2006 Consumer Canada
Primary
Concomitant
Hospitalisation Hospitalization Female 170 lb 5/12/2006 Consumer Canada
Primary
Concomitant
Renal Disorder Other Serious 4/6/2006 54 Female 135 lb 5/19/2006 Other Health Professional Canada
Primary
Concomitant
Staphylococcal Infection Hospitalization 4/21/2006 Female 170 lb 6/21/2006 Consumer Canada
Primary
Concomitant
Pulmonary Fibrosis Death 4/19/2006 Female 325 lb 7/7/2006 Physician Canada
Primary
Concomitant
Thyroid Neoplasm Life Threatening 4/21/2006 Female 167 lb 8/4/2006 Other Health Professional Canada
Primary
Concomitant
Shunt Occlusion Hospitalization 7/18/2006 Female 8/10/2006 Consumer Canada
Primary
Concomitant
Shock Haemorrhagic Other Serious 5/1/2005 Female 104 lb 8/10/2006 Physician Germany
Primary
Secondary
Concomitant
Metastasis Other Serious 6/20/2006 75 Female 8/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Radiation Oesophagitis Hospitalization 5/1/2005 Male 8/17/2006 Physician Germany
Primary
Concomitant
Shunt Occlusion Hospitalization 7/18/2006 Female 9/8/2006 Consumer Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 4/6/2006 54 Female 135 lb 9/22/2006 Other Health Professional Canada
Primary
Concomitant
Radiation Oesophagitis Hospitalization 5/1/2005 Male 9/28/2006 Physician Germany
Primary
Concomitant
Shunt Occlusion Hospitalization 7/18/2006 Female 11/7/2006 Consumer Canada
Primary
Concomitant
Ventricular Fibrillation Hospitalization Male 12/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 4/29/2005 Female 104 lb 1/17/2007 Consumer United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 Female 1/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/2/2007 Female 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Breast Mass Other Serious Female 148 lb 2/9/2007 Consumer Canada
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 Female 6/4/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 2/21/2007 56 Female 6/12/2007 Physician Germany
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 10/15/2006 Female 201 lb 7/5/2007 Physician Italy
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 2/21/2007 56 Female 8/18/2007 Physician Germany
Primary
Secondary
Concomitant
Tibia Fracture Other Serious 9/22/2007 Female 150 lb 10/12/2007 Canada
Primary
Concomitant
Syncope Other Serious 2/1/2007 Male 141 lb 11/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Life Threatening 3/1/2007 Male 196 lb 11/16/2007 Germany
Primary
Concomitant
Staphylococcal Infection Other Serious 9/19/2006 Male 11/28/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Septic Shock Hospitalization 8/15/2007 Female 170 lb 11/29/2007 United Kingdom
Primary
Concomitant
Rectosigmoid Cancer Other Serious 4/1/2007 Female 1/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 12/15/2006 56 Female 2/8/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Ischaemia Death 10/3/2007 Female 104 lb 2/25/2008 United Kingdom
Primary
Concomitant
Tibia Fracture Other Serious 9/22/2007 Female 150 lb 3/6/2008 Canada
Primary
Concomitant
Mobility Decreased 1/1/2008 Female 3/15/2008 United States
Primary
Concomitant
Injection Site Urticaria 1/31/2008 Female 124 lb 3/15/2008 United States
Primary
Concomitant
White Blood Cell Count Abnormal Hospitalization 5/6/2007 Male 229 lb 3/25/2008 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 10/15/2006 Female 201 lb 4/16/2008 Physician Italy
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/29/2007 Female 187 lb 4/25/2008 United Kingdom
Primary
Concomitant
Rectosigmoid Cancer Other Serious 4/1/2007 Female 5/28/2008 Other Health Professional France
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/2/2007 49 Female 6/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myositis Other Serious 70 Female 7/7/2008 Physician Switzerland
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/15/2007 Female 187 lb 7/11/2008 United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/2/2008 49 Female 7/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Surgery Hospitalization 7/1/2007 Male 242 lb 7/24/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/28/2008 Female 8/6/2008 Germany
Primary
Secondary
Concomitant
Myocardial Infarction Death 7/30/2008 Female 150 lb 8/15/2008 Canada
Primary
Concomitant
Weight Decreased Other Serious 7/11/2008 Male 150 lb 8/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Colitis Hospitalization 55 Female 128 lb 9/8/2008 Germany
Primary
Concomitant
Bronchial Carcinoma Death 8/10/2008 Male 150 lb 9/30/2008 United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 49 Female 10/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bronchial Carcinoma Death 8/10/2008 Male 150 lb 10/2/2008 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 7/11/2008 Male 150 lb 10/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Encephalitis Hospitalization 5/13/2008 Female 170 lb 10/8/2008 United Kingdom
Primary
Concomitant
Liver Injury Other Serious 19 Female 10/24/2008 Germany
Primary
Secondary
Musculoskeletal Chest Pain 10/16/2008 Female 12/12/2008 United States
Primary
Concomitant
Weight Decreased 10/1/2008 Female 105 lb 12/12/2008 Consumer United States
Primary
Concomitant
Erythema Multiforme Disability 11/1/2008 Female 154 lb 12/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 4/24/2008 69 Male 1/22/2009 Physician Germany
Primary
Secondary
Concomitant
Erythema Multiforme Disability 52 Female 154 lb 1/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 4/24/2008 69 Male 2/2/2009 Physician Germany
Primary
Secondary
Concomitant
Human Polyomavirus Infection Hospitalization 12/22/2008 Female 169 lb 2/9/2009 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 7/11/2008 Male 150 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious 74 Male 143 lb 2/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 10/7/2008 74 Male 143 lb 3/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 10/7/2008 74 Male 143 lb 5/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 10/7/2008 74 Male 143 lb 5/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urosepsis Hospitalization Female 187 lb 7/1/2009 United Kingdom
Primary
Concomitant
Osteonecrosis Hospitalization 4/24/2008 69 Male 8/3/2009 Physician Germany
Primary
Secondary
Concomitant
Exostosis Hospitalization 1/1/2009 46 Female 8/21/2009 Consumer Germany
Primary
Secondary
Concomitant
Musculoskeletal Stiffness 12/1/2006 Female 170 lb 9/11/2009 Consumer United States
Primary
Concomitant
Wound Dehiscence Life Threatening 10/17/2005 67 Male 9/28/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/28/2009 Female 10/12/2009 United Kingdom
Primary
Concomitant
Venous Thrombosis Other Serious 4/1/2007 Female 11/3/2009 Physician France
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Hospitalization 8/1/2009 58 Male 212 lb 11/5/2009 Physician Germany
Primary
Concomitant
Syncope Other Serious 11/16/2009 Male 200 lb 11/25/2009 Canada
Primary
Concomitant
Myocardial Infarction Life Threatening 12/11/2008 57 Female 165 lb 12/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 7/27/2009 Male 216 lb 1/8/2010 Consumer United Kingdom
Primary
Secondary
Renal Disorder Hospitalization 1/15/2008 46 Male 331 lb 1/25/2010 Germany
Primary
Secondary
Concomitant
Skin Cancer Hospitalization 4/24/2008 69 Male 2/2/2010 Physician Germany
Primary
Secondary
Concomitant
Leukocytosis Other Serious 1/1/2009 Male 220 lb 2/4/2010 Germany
Primary
Concomitant
Wound Dehiscence Life Threatening 10/17/2005 67 Male 2/5/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 7/27/2009 Male 216 lb 2/11/2010 Consumer Germany
Primary
Secondary
Leukocytosis Other Serious 1/1/2009 Male 220 lb 3/19/2010 Germany
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/28/2009 Female 3/26/2010 United Kingdom
Primary
Concomitant
Leukocytosis Other Serious 1/1/2009 57 Male 220 lb 6/10/2010 Physician Germany
Primary
Concomitant
Leukocytosis Other Serious 1/1/2009 57 Male 220 lb 6/24/2010 Physician Germany
Primary
Concomitant
Peripheral Vascular Disorder Hospitalization 10/17/2009 59 Male 171 lb 6/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious Male 8/19/2010 Consumer Germany
Primary
Concomitant
Swollen Tongue Other Serious 1/1/2010 71 Female 213 lb 9/2/2010 Consumer United States
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 1/1/2010 71 Female 213 lb 9/16/2010 Consumer United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 12/23/2009 73 Female 9/23/2010 Physician Germany
Primary
Concomitant
Injection Site Reaction 2/1/2010 12/22/2010 Consumer United States
Primary
Concomitant
Wheezing Disability 12/20/2010 64 Male 225 lb 1/6/2011 Physician United Kingdom
Primary
Concomitant
Headache Male 200 lb 1/29/2011 Consumer United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 12/1/2009 60 Female 153 lb 1/30/2011 Physician United States
Primary
Concomitant
Arthralgia Hospitalization 12/23/2009 73 Female 2/8/2011 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 11/1/2010 68 Female 5/4/2011 Consumer Canada
Primary
Concomitant
Bone Fistula Hospitalization 5/15/2010 53 Female 185 lb 6/9/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Chest Pain Other Serious 3/18/2009 61 Male 220 lb 8/17/2011 Physician United Kingdom
Primary
Concomitant
Pulmonary Congestion Other Serious 11/15/2008 71 Male 8/22/2011 Physician Germany
Primary
Concomitant
Bone Cyst Hospitalization 5/15/2010 53 Female 185 lb 8/31/2011 Physician Germany
Primary
Secondary
Concomitant
Limb Deformity Other Serious 1/1/2006 48 Female 167 lb 9/26/2011 Physician Canada
Primary
Concomitant
Gait Disturbance Other Serious Female 9/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 1/1/2006 48 Female 167 lb 10/14/2011 Physician Canada
Primary
Concomitant
Infection Other Serious 7/28/2011 70 Female 146 lb 10/25/2011 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Other Serious 1/1/2006 48 Female 167 lb 10/28/2011 Physician Canada
Primary
Concomitant
Fistula Hospitalization 5/1/2010 54 Female 11/7/2011 Germany
Primary
Secondary
Concomitant
Bone Fistula Hospitalization 5/15/2010 53 Female 185 lb 11/10/2011 Physician Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 3/24/2011 50 Female 199 lb 11/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Polyneuropathy Other Serious 7/1/2011 12/23/2011 Physician Germany
Primary
Concomitant
Polyneuropathy Other Serious 5/1/2011 12/23/2011 Other Health Professional Germany
Primary
Concomitant
Skin Necrosis Hospitalization 5/1/2010 53 Female 185 lb 1/26/2012 Physician Germany
Primary
Secondary
Concomitant
Fistula Hospitalization 5/1/2010 54 Female 2/7/2012 Physician Germany
Primary
Secondary
Concomitant
Retinopathy Other Serious 1/31/2012 56 Male 2/15/2012 Consumer Canada
Primary
Concomitant
Klebsiella Infection Hospitalization 5/1/2010 53 Female 185 lb 2/21/2012 Germany
Primary
Secondary
Concomitant
Endometrial Cancer Stage Iii Life Threatening 51 Female 132 lb 2/24/2012 Other Health Professional United Kingdom
Primary
Concomitant
Loss Of Consciousness Hospitalization 12/29/2011 77 Female 2/29/2012 Consumer Germany
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 11/1/2010 68 Female 2/29/2012 Physician Canada
Primary
Concomitant
Hyponatraemia Hospitalization 11/1/2010 68 Female 3/6/2012 Physician Canada
Primary
Concomitant
Arthralgia Hospitalization 11/1/2008 70 Female 3/16/2012 Physician Germany
Primary
Concomitant
Cardiac Arrest Death 6/4/2011 72 Female 3/28/2012 Physician Germany
Primary
Concomitant
Hypertension Hospitalization 1/25/2012 46 Female 209 lb 4/26/2012 Physician Germany
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 7/19/2011 75 Female 121 lb 5/16/2012 Physician Germany
Primary
Secondary
Concomitant
Skin Ulcer Disability 10/5/2010 Male 6/28/2012 Physician Germany
Primary
Secondary
Concomitant
Vasculitis Other Serious 11/1/2011 73 Male 7/23/2012 Other Health Professional Canada
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 6/1/2012 66 Male 403 lb 7/26/2012 Physician Germany
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 7/19/2011 75 Female 121 lb 8/3/2012 Physician Germany
Primary
Secondary
Concomitant
Eyelid Oedema 4/9/2012 61 Female 8/7/2012 Consumer United States
Primary
Secondary
Concomitant
Fistula Hospitalization 5/1/2010 53 Female 185 lb 8/22/2012 Physician Germany
Primary
Secondary
Concomitant
Cholelithiasis Other Serious 1/1/2009 63 Female 143 lb 8/22/2012 Physician Germany
Primary
Concomitant
Diarrhoea Haemorrhagic Death 12/29/2010 Male 154 lb 6/24/2013 Physician De
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 7/2011 75 Female 121 lb 12/26/2012 Physician De
Primary
Concomitant
Treatment Noncompliance 1/5/2011 63 Female 10/23/2012 Consumer Us
Primary
Concomitant
Rash Pruritic 1/19/2012 76 Female 129 lb 10/30/2012 Physician Gb
Primary
Concomitant
Endometrial Cancer Stage Iii Life Threatening 9/2011 51 Female 132 lb 10/15/2012 Other Health Professional Gb
Primary
Concomitant
Pleural Neoplasm Hospitalization 10/20/2011 82 Male 185 lb 5/21/2013 Physician De
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 12/12/2008 56 Female 9/25/2012 Physician Gb
Primary
Concomitant
Therapeutic Response Decreased Female 10/25/2012 Physician Us
Primary
Concomitant
Swelling Face 12/29/2011 71 Male 10/24/2012 Physician Us
Primary
Concomitant
Bronchitis Male 215 lb 11/8/2012 Consumer Us
Primary
Concomitant
Transient Ischaemic Attack Other Serious 10/29/2012 62 Male 169 lb 12/10/2012 Consumer Ca
Primary
Concomitant
Pruritus Disability 8/2012 57 Female 12/5/2012 Other Health Professional Gb
Primary
Concomitant
Psoriasis Other Serious Female 12/27/2012 Other Health Professional Gb
Primary
Concomitant
Spondylitis Hospitalization 6/15/2012 61 Female 1/10/2013 Physician De
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 9/26/2012 60 Female 187 lb 1/14/2013 Other Health Professional Gb
Primary
Concomitant
Postoperative Wound Complication Hospitalization 2/2012 74 Female 4/9/2013 Physician Ca
Primary
Concomitant
Synovectomy Hospitalization 5/31/2012 Male 2/21/2013 Physician Country Not Specified
Primary
Concomitant
Pallor 4/9/2012 61 Female 1/30/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2012 Male 2/15/2013 Physician Country Not Specified
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 9/26/2012 60 Female 187 lb 1/16/2013 Physician Gb
Primary
Concomitant

Drug Data