Leflunomide combined with Prednisone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Disorder Hospitalization 11/16/2005 Female 162 lb 1/3/2006 Consumer United States
Primary
Concomitant
Depression Hospitalization 12/19/2005 Female 140 lb 1/13/2006 United States
Primary
Concomitant
Toe Amputation Other Serious 8/1/2003 Female 199 lb 1/20/2006 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 11/16/2005 Female 162 lb 1/24/2006 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 8/11/2005 Female 1/27/2006 Italy
Primary
Concomitant
Osteoarthritis Other Serious 8/1/2005 Female 135 lb 1/27/2006 United States
Primary
Concomitant
Pancreatitis Hospitalization 1/4/2006 31 Female 128 lb 1/25/2006 Physician Mexico
Primary
Concomitant
Sudden Death Death 7/27/2004 Female 2/1/2006 United States
Primary
Concomitant
Sudden Death Death 7/27/2004 Female 2/1/2006 United States
Primary
Concomitant
Diverticulitis Hospitalization 1/1/2006 Female 155 lb 2/1/2006 Canada
Primary
Concomitant
Muscle Spasms Hospitalization 12/9/2005 Female 176 lb 2/2/2006 Canada
Primary
Secondary
Concomitant
Psoriasis Other Serious 8/4/2005 Female 120 lb 2/6/2006 Canada
Primary
Concomitant
Peridiverticular Abscess Hospitalization 1/1/2006 Female 155 lb 2/17/2006 Physician Canada
Primary
Concomitant
Meningitis Cryptococcal Hospitalization 12/7/2004 45 Male 2/20/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/28/2006 Consumer United States
Primary
Secondary
Concomitant
Cutaneous Lupus Erythematosus Other Serious 64 Female 3/6/2006 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 5/9/2005 58 Female 150 lb 12/27/2005 Other Health Professional United States
Primary
Concomitant
Tooth Infection Other Serious 2/1/2006 Female 130 lb 3/16/2006 Consumer Canada
Primary
Concomitant
Rheumatoid Arthritis Life Threatening 9/1/2002 54 Female 190 lb 3/17/2006 Physician Germany
Primary
Secondary
Concomitant
Eosinophilia Other Serious 7/1/2001 55 Female 3/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Acute Febrile Neutrophilic Dermatosis Other Serious 9/5/2005 Female 148 lb 3/30/2006 France
Primary
Concomitant
Wound Dehiscence Other Serious 7/29/2005 Female 117 lb 4/7/2006 Consumer Canada
Primary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 4/25/2006 Consumer United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 7/29/2005 Female 117 lb 5/30/2006 Consumer Canada
Primary
Concomitant
Yellow Skin Other Serious 4/1/1997 Female 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Hip Arthroplasty Hospitalization 5/5/2006 Female 140 lb 6/7/2006 Consumer Canada
Primary
Concomitant
Staphylococcal Infection Hospitalization 4/21/2006 Female 170 lb 6/21/2006 Consumer Canada
Primary
Concomitant
Tooth Infection Other Serious 5/14/2004 54 Male 229 lb 6/28/2006 Physician United States
Primary
Concomitant
Drug Ineffective 5/1/2006 Male 220 lb 6/30/2006 Consumer United States
Primary
Concomitant
Diffuse Large B-cell Lymphoma Stage Iii Other Serious 6/27/2005 Female 161 lb 7/11/2006 Other Health Professional United States
Primary
Concomitant
Propionibacterium Infection Other Serious 48 Female 7/14/2006 Spain
Primary
Secondary
Concomitant
Streptococcal Infection Life Threatening 7/8/2006 69 Female 7/21/2006 Physician Spain
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 66 Female 6/5/2006 United States
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Stage Iii Other Serious 6/27/2005 Female 161 lb 8/8/2006 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/14/2004 54 Male 229 lb 8/11/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/6/2006 54 Female 135 lb 9/22/2006 Other Health Professional Canada
Primary
Concomitant
Sepsis Hospitalization 1/1/2006 59 Female 192 lb 9/29/2006 Physician United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 59 Female 10/2/2006 Consumer United States
Primary
Concomitant
Wound Dehiscence Other Serious 7/29/2005 Female 117 lb 10/3/2006 Consumer Canada
Primary
Concomitant
Tooth Avulsion Other Serious 4/1/2005 69 Female 12/27/2006 Other Health Professional France
Primary
Concomitant
Urinary Tract Infection Other Serious 4/14/2006 Female 1/17/2007 Consumer Brazil
Primary
Concomitant
Dyspnoea Hospitalization 10/16/2006 Female 155 lb 1/18/2007 Consumer United States
Primary
Concomitant
Osteonecrosis Hospitalization 2/1/2004 64 Female 110 lb 1/19/2007 Physician Spain
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/5/2006 37 Female 1/18/2007 Consumer Canada
Primary
Concomitant
Death Death Female 128 lb 1/22/2007 France
Primary
Concomitant
Hepatic Enzyme Abnormal Other Serious 11/1/2006 Female 122 lb 1/27/2007 Consumer Canada
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 10/17/2006 Female 152 lb 1/27/2007 Physician Germany
Primary
Concomitant
Localised Infection Hospitalization 12/18/2006 Male 160 lb 1/27/2007 Pharmacist Canada
Primary
Concomitant
Transplant Rejection Hospitalization 8/24/2005 Male 140 lb 1/30/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 1/17/2005 Female 145 lb 2/7/2007 Physician Canada
Primary
Concomitant
Infection Hospitalization 9/6/2006 Female 2/8/2007 Consumer United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 11/13/2006 56 Male 2/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 127 lb 2/28/2007 Consumer Canada
Primary
Concomitant
Pustular Psoriasis Other Serious 19 Female 3/9/2007 Physician Canada
Primary
Concomitant
Coccidioidomycosis Other Serious 60 Female 3/22/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 127 lb 3/22/2007 Consumer Canada
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/5/2006 Female 178 lb 3/23/2007 Physician United States
Primary
Concomitant
Pharyngolaryngeal Pain 2/16/2007 47 Female 130 lb 3/27/2007 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 12/18/2006 Male 160 lb 3/29/2007 Pharmacist Canada
Primary
Concomitant
Gallbladder Operation Other Serious Male 190 lb 4/4/2007 Consumer Canada
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 3/12/2007 Female 117 lb 4/11/2007 Physician France
Primary
Concomitant
Smear Cervix Abnormal Hospitalization 1/1/2007 Female 108 lb 7/11/2007 Consumer United States
Primary
Concomitant
Diverticulitis Hospitalization 1/1/2006 Female 119 lb 7/19/2007 Portugal
Primary
Concomitant
Pain In Extremity Hospitalization 7/27/2007 Female 122 lb 8/20/2007 Canada
Primary
Concomitant
Intervertebral Disc Compression Hospitalization 7/1/2007 Female 128 lb 8/30/2007 Physician United States
Primary
Concomitant
Surgery Hospitalization 7/18/2007 Female 130 lb 8/31/2007 Consumer United States
Primary
Secondary
Concomitant
Oedema Hospitalization 23 Female 9/7/2007 Czech Republic
Primary
Concomitant
Upper Limb Deformity Other Serious 1/1/2006 64 Female 139 lb 9/7/2007 Brazil
Primary
Concomitant
Upper Limb Deformity Other Serious 1/1/2006 64 Female 139 lb 9/20/2007 Brazil
Primary
Concomitant
Foot Amputation Hospitalization 10/11/2006 34 Male 154 lb 9/18/2007 Physician United States
Primary
Concomitant
Neoplasm Skin Other Serious 9/15/2007 Male 9/26/2007 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious Female 130 lb 9/28/2007 Canada
Primary
Concomitant
Tibia Fracture Other Serious 9/22/2007 Female 150 lb 10/12/2007 Canada
Primary
Concomitant
Sinus Bradycardia Other Serious 1/1/2006 Female 10/12/2007 Belgium
Primary
Secondary
Concomitant
Foot Operation Other Serious 9/22/2007 Female 10/15/2007 Brazil
Primary
Concomitant
Spinal Column Stenosis Other Serious 7/1/2006 Female 162 lb 10/18/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 11/1/2005 Female 185 lb 10/24/2007 Other Health Professional United States
Primary
Concomitant
Leukoencephalopathy Other Serious 33 Female 10/24/2007 Physician El Salvador
Primary
Concomitant
Respiratory Disorder Female 10/25/2007 Consumer United States
Primary
Concomitant
Rhinitis Other Serious 10/3/2007 50 Female 143 lb 10/26/2007 Brazil
Primary
Secondary
Concomitant
Vasculitis Cerebral Other Serious 3/1/2007 33 Female 11/1/2007 Physician El Salvador
Primary
Concomitant
Medical Device Implantation Other Serious 9/22/2007 Female 141 lb 11/2/2007 Brazil
Primary
Concomitant
Rhinitis Other Serious 10/3/2007 50 Female 143 lb 11/2/2007 Brazil
Primary
Secondary
Concomitant
Pain Other Serious 11/1/2006 Female 122 lb 11/7/2007 Canada
Primary
Concomitant
Uterine Disorder Hospitalization 9/7/2007 45 Female 132 lb 12/10/2007 Brazil
Primary
Concomitant
Neoplasm Skin Other Serious 8/30/2007 Male 12/11/2007 Physician United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 53 Female 12/3/2007 Japan
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 11/27/2007 Female 154 lb 12/11/2007 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 60 Female 12/4/2007 Netherlands
Primary
Secondary
Concomitant
Pulmonary Cavitation Other Serious 68 Female 12/4/2007 Netherlands
Primary
Secondary
Concomitant
Pulmonary Cavitation Other Serious 78 Male 12/4/2007 Netherlands
Primary
Secondary
Concomitant
Lobar Pneumonia Other Serious 57 Male 12/4/2007 Netherlands
Primary
Secondary
Concomitant
Injection Site Pain 6/1/2005 Female 123 lb 12/14/2007 Consumer United States
Primary
Concomitant
Nausea 9/1/2007 Female 160 lb 12/14/2007 United States
Primary
Concomitant
Salmonellosis 1/1/2006 Female 166 lb 12/14/2007 United States
Primary
Concomitant
Pneumonia Hospitalization 6/1/2007 Male 228 lb 12/14/2007 Consumer United States
Primary
Concomitant
Injection Site Irritation 9/1/2007 Female 120 lb 12/14/2007 Consumer United States
Primary
Concomitant
Accidental Exposure 9/2/2007 Female 136 lb 12/14/2007 Consumer United States
Primary
Concomitant
Paraesthesia 1/1/2006 Female 120 lb 12/14/2007 Consumer United States
Primary
Concomitant
Swelling 1/1/2005 Female 163 lb 12/14/2007 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2007 Male 164 lb 12/14/2007 United States
Primary
Concomitant
Accidental Exposure 10/4/2007 Female 118 lb 12/14/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 10/1/2007 Female 110 lb 12/14/2007 Consumer United States
Primary
Concomitant
Pyrexia 11/21/2007 Female 12/15/2007 United States
Primary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 12/19/2007 Germany
Primary
Concomitant
Lower Limb Fracture Life Threatening 8/29/2007 Female 12/20/2007 Consumer United States
Primary
Concomitant
Vertebral Abscess Other Serious 9/8/2007 Female 12/21/2007 Physician Germany
Primary
Concomitant
Pain In Extremity Other Serious 12/1/2007 Female 163 lb 12/26/2007 Consumer United States
Primary
Concomitant
Rectosigmoid Cancer Other Serious 4/1/2007 Female 1/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 6/21/2007 Male 248 lb 1/22/2008 Other Health Professional United States
Primary
Concomitant
Tinnitus Hospitalization 1/7/2008 Female 110 lb 1/22/2008 Physician Brazil
Primary
Concomitant
Peripheral Sensorimotor Neuropathy Other Serious 65 Male 1/11/2008 Australia
Primary
Secondary
Rheumatoid Arthritis Other Serious 4/1/2005 69 Female 2/22/2008 Other Health Professional France
Primary
Concomitant
Pruritus 12/13/2007 Female 168 lb 3/14/2008 United States
Primary
Concomitant
Dyspnoea 12/5/2007 Male 230 lb 3/14/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased 10/1/2007 Female 154 lb 3/14/2008 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis 12/1/2007 Male 160 lb 3/14/2008 United States
Primary
Concomitant
Injection Site Pain 2/1/2007 Female 190 lb 3/14/2008 United States
Primary
Concomitant
Sinusitis 12/28/2007 Female 115 lb 3/14/2008 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 12/1/2007 Female 302 lb 3/15/2008 Physician United States
Primary
Concomitant
Injection Site Pain 10/1/2007 Male 206 lb 3/15/2008 Consumer United States
Primary
Concomitant
Pain 1/18/2008 Female 156 lb 3/15/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/1/2007 Female 3/15/2008 Consumer United States
Primary
Concomitant
Dizziness Male 197 lb 3/15/2008 United States
Primary
Concomitant
Sinusitis 2/5/2008 Female 150 lb 3/15/2008 United States
Primary
Concomitant
Injection Site Urticaria 1/31/2008 Female 124 lb 3/15/2008 United States
Primary
Concomitant
Paranasal Sinus Hypersecretion 2/2/2008 Female 140 lb 3/15/2008 United States
Primary
Concomitant
Skin Exfoliation 5/1/2007 Female 3/15/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 2/15/2008 Female 190 lb 3/15/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 2/19/2008 Male 195 lb 3/15/2008 Consumer United States
Primary
Concomitant
Skin Exfoliation Hospitalization 7/1/2007 56 Male 3/21/2008 Other Health Professional France
Primary
Concomitant
Metrorrhagia Hospitalization 5/1/2006 Female 143 lb 4/3/2008 Physician Italy
Primary
Concomitant
Vertigo Hospitalization 8/11/2005 Female 4/10/2008 Physician Italy
Primary
Concomitant
Oedema Peripheral Hospitalization 10/15/2006 Female 201 lb 4/16/2008 Physician Italy
Primary
Concomitant
Myocardial Infarction Hospitalization 11/13/2006 Female 128 lb 4/25/2008 France
Primary
Concomitant
Nasopharyngitis Other Serious 4/1/2008 Female 165 lb 4/25/2008 Canada
Primary
Concomitant
Weight Decreased Life Threatening 4/25/2008 Male 161 lb 4/29/2008 Physician United States
Primary
Secondary
Pneumonia Legionella Death 4/17/2008 Male 5/1/2008 Physician New Zealand
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 8/1/2007 Male 181 lb 5/6/2008 Brazil
Primary
Concomitant
Interacting
Osteonecrosis Hospitalization 2/1/2004 64 Female 110 lb 6/6/2008 Physician Spain
Primary
Concomitant
Cryptogenic Organising Pneumonia Other Serious 64 Female 6/24/2008 Consumer United Kingdom
Primary
Concomitant
Femur Fracture Other Serious 10/1/2004 63 Female 6/25/2008 Physician Australia
Primary
Concomitant
Nerve Root Lesion Hospitalization 5/9/2008 34 Male 6/26/2008 Physician Finland
Primary
Concomitant
Infarction Hospitalization 2/21/2008 Male 6/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 2/1/2000 67 Female 93 lb 7/3/2008 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 6/10/2008 14 Male 7/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Myositis Other Serious 70 Female 7/7/2008 Physician Switzerland
Primary
Concomitant
Cerebrovascular Accident Hospitalization 2/21/2008 Male 7/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant

Drug Data