Leflunomide combined with Prednisolone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cerebrovascular Accident Death 9/1/2005 Female 176 lb 1/13/2006 Physician United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/1/2005 Male 181 lb 1/18/2006 United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 6/30/2005 Female 1/23/2006 Germany
Primary
Concomitant
Pregnancy Other Serious 11/23/2005 29 Female 1/26/2006 Greece
Primary
Concomitant
Respiratory Failure Life Threatening 5/30/2005 Male 168 lb 1/27/2006 Physician United Kingdom
Primary
Concomitant
Polyarthritis Hospitalization 4/19/2005 41 Female 1/27/2006 France
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/30/2005 Female 2/3/2006 Germany
Primary
Concomitant
Polyarthritis Hospitalization 4/19/2005 41 Female 2/7/2006 France
Primary
Secondary
Concomitant
Vasculitis Life Threatening 3/7/2005 Male 190 lb 2/9/2006 United Kingdom
Primary
Concomitant
Joint Arthroplasty Hospitalization 58 Female 2/14/2006 Physician Germany
Primary
Concomitant
Impaired Healing Hospitalization 5/4/2005 65 Male 2/21/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Synovectomy Hospitalization 6/2/2005 Male 163 lb 2/23/2006 Physician Germany
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 8/1/2003 Female 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/27/2006 57 Female 2/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Intestinal Perforation Hospitalization 1/15/2005 63 Female 2/28/2006 Physician Australia
Primary
Secondary
Respiratory Failure Hospitalization 6/30/2005 Female 3/9/2006 Physician Germany
Primary
Concomitant
Lethargy Hospitalization 5/21/2005 Female 137 lb 3/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Function Test Decreased Hospitalization 1/1/2004 75 Male 3/11/2006 United Kingdom
Primary
Concomitant
Secondary Amyloidosis Hospitalization 11/27/2005 73 Female 3/30/2006 Physician Greece
Primary
Concomitant
Respiratory Failure Hospitalization 6/30/2005 Female 4/4/2006 Physician Germany
Primary
Concomitant
Sepsis Hospitalization Female 4/10/2006 Physician Germany
Primary
Concomitant
Sepsis Hospitalization Female 4/17/2006 Physician Germany
Primary
Concomitant
Mouth Ulceration Other Serious 1/29/2006 54 Female 112 lb 4/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Tract Infection Hospitalization 11/15/2005 Male 122 lb 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Hospitalization 7/1/2002 44 Female 4/27/2006 Norway
Primary
Concomitant
Muscular Weakness Hospitalization 7/27/2004 67 Male 4/28/2006 Norway
Primary
Concomitant
Hypertension Hospitalization 7/1/2002 44 Female 5/3/2006 Norway
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/7/2005 Female 126 lb 5/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Autoimmune Hepatitis Other Serious 1/23/2006 Female 198 lb 5/5/2006 Physician Germany
Primary
Concomitant
Staphylococcal Infection Other Serious 12/1/2004 Female 176 lb 5/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Streptococcal Infection Hospitalization Female 5/9/2006 Physician Germany
Primary
Concomitant
Transaminases Increased Other Serious 11/1/2005 Female 198 lb 5/22/2006 Physician Germany
Primary
Concomitant
Tooth Extraction Disability 12/22/2005 52 Female 5/23/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Synovectomy Hospitalization 11/10/2005 34 Female 5/24/2006 Physician Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/5/2005 Female 148 lb 5/25/2006 Greece
Primary
Concomitant
Osteonecrosis Hospitalization 9/15/2003 67 Female 5/31/2006 Other Health Professional Australia
Primary
Concomitant
Osteonecrosis Hospitalization 9/15/2003 67 Female 6/5/2006 Physician Australia
Primary
Concomitant
Transaminases Increased Other Serious 11/1/2005 Female 198 lb 6/2/2006 Physician Germany
Primary
Concomitant
Nausea Other Serious 4/20/2006 Male 247 lb 6/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Malabsorption Hospitalization 4/7/2006 Female 128 lb 6/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Thrombosis Death 4/4/2006 Male 185 lb 7/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tooth Abscess Hospitalization 6/30/2006 51 Female 7/21/2006 Physician Greece
Primary
Secondary
Concomitant
B-cell Lymphoma Stage Ii Other Serious 4/13/2006 68 Male 132 lb 7/31/2006 Other Health Professional Germany
Primary
Concomitant
Pulmonary Tuberculosis Death 7/6/2004 Male 126 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/25/2005 Male 181 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 5/2/2006 Male 188 lb 8/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lethargy Other Serious 5/17/2005 Female 137 lb 8/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious Female 8/10/2006 Physician Ireland
Primary
Concomitant
Shock Haemorrhagic Other Serious 5/1/2005 Female 104 lb 8/10/2006 Physician Germany
Primary
Secondary
Concomitant
Proctitis Ulcerative Other Serious 8/15/2005 56 Female 8/14/2006 Physician Germany
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 1/1/2005 Female 132 lb 8/17/2006 Physician Germany
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 11/7/2005 Female 126 lb 8/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Knee Arthroplasty Hospitalization 1/24/2006 Female 203 lb 8/25/2006 Physician Germany
Primary
Concomitant
Depression Hospitalization 7/4/2006 22 Female 8/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Abscess Limb Hospitalization 12/1/2005 63 Female 172 lb 9/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteitis Hospitalization 9/11/2006 Physician Belgium
Primary
Concomitant
Pneumonitis Hospitalization 1/1/2004 75 Male 9/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonitis Hospitalization 1/1/2004 75 Male 9/12/2006 United Kingdom
Primary
Concomitant
Ventricular Arrhythmia Life Threatening 2/22/2006 Female 9/21/2006 Physician Germany
Primary
Concomitant
Wegener's Granulomatosis Hospitalization 11/3/2005 Female 9/21/2006 Physician Germany
Primary
Secondary
Concomitant
Volvulus Other Serious 10/29/2005 Male 115 lb 9/27/2006 Consumer United Kingdom
Primary
Concomitant
Volvulus Other Serious 10/29/2005 Male 115 lb 10/4/2006 Consumer United Kingdom
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 7/1/2006 67 Female 10/5/2006 Physician Austria
Primary
Concomitant
Cerebral Infarction Other Serious Male 170 lb 10/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization Female 10/13/2006 Physician Australia
Primary
Concomitant
Streptococcal Infection Life Threatening 6/1/2006 Female 10/20/2006 Physician Australia
Primary
Concomitant
Bursitis Hospitalization 12/7/2005 Male 10/30/2006 Physician Switzerland
Primary
Concomitant
Urinary Retention Other Serious 8/15/2006 Male 223 lb 11/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lipase Increased Hospitalization 8/1/2006 Female 220 lb 11/3/2006 Physician Germany
Primary
Concomitant
Vulvar Dysplasia Other Serious 4/1/2006 51 Female 11/8/2006 Physician Turkey
Primary
Concomitant
Surgery Death Female 207 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 7/1/2005 Male 11/16/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Ruptured Cerebral Aneurysm Hospitalization 7/5/2005 Female 165 lb 11/17/2006 Physician Germany
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/6/2006 Female 11/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 10/10/2006 Male 11/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Sigmoiditis Hospitalization 9/29/2006 Female 12/1/2006 Physician Belgium
Primary
Concomitant
Unevaluable Event Hospitalization 11/14/2006 75 Female 154 lb 12/1/2006 Physician Greece
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 8/17/2006 70 Female 12/4/2006 Physician Greece
Primary
Concomitant
Metastases To Bone Other Serious Male 12/8/2006 Physician New Zealand
Primary
Concomitant
Tooth Abscess Life Threatening 9/25/2006 Female 12/11/2006 Physician New Zealand
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/5/2005 Female 148 lb 12/13/2006 Greece
Primary
Concomitant
Diarrhoea Hospitalization 8/29/2006 Female 121 lb 12/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 5/1/2006 Female 123 lb 12/14/2006 Physician Switzerland
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 5/1/2006 Female 123 lb 12/19/2006 Physician Switzerland
Primary
Secondary
Concomitant
Tooth Abscess Life Threatening 9/25/2006 Female 12/19/2006 Physician New Zealand
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/9/2006 Female 12/20/2006 Physician
Primary
Concomitant
Sepsis Hospitalization 4/5/2005 Female 148 lb 12/27/2006 Greece
Primary
Concomitant
Tuberculosis Hospitalization 8/17/2006 70 Female 12/27/2006 Physician Greece
Primary
Concomitant
Cellulitis Hospitalization 11/15/2006 Female 174 lb 1/16/2007 Physician United Kingdom
Primary
Concomitant
Surgery Death 7/26/2006 Female 207 lb 1/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Mitral Valve Incompetence Hospitalization 12/15/2006 Female 174 lb 1/19/2007 Physician United Kingdom
Primary
Concomitant
Coronary Artery Thrombosis Death 4/4/2006 Male 185 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sigmoiditis Hospitalization 9/29/2006 Female 1/19/2007 Physician Belgium
Primary
Concomitant
Hip Fracture Hospitalization 7/18/2006 Female 1/19/2007 Other Health Professional Belgium
Primary
Concomitant
Scab Other Serious 7/14/2006 39 Male 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 7/1/2006 76 Female 1/22/2007 Physician Greece
Primary
Concomitant
Vasculitis Other Serious 1/1/2006 Male 163 lb 1/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Joint Dislocation Hospitalization 8/23/2004 Female 152 lb 1/24/2007 Consumer United Kingdom
Primary
Concomitant
Psoriasis Hospitalization Female 1/25/2007 Physician Belgium
Primary
Concomitant
Myocardial Infarction Death 8/18/2006 Male 115 lb 1/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 7/1/2006 Female 201 lb 1/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 Female 1/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/26/2006 Male 212 lb 2/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Tract Infection Hospitalization 7/1/2006 76 Female 2/2/2007 Physician Greece
Primary
Secondary
Concomitant
Wegener's Granulomatosis Other Serious 2/24/2005 Female 2/6/2007 Physician Germany
Primary
Secondary
Concomitant
Osteitis Hospitalization 10/28/2005 Female 2/7/2007 Physician Belgium
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 Female 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Psoriasis Hospitalization Female 2/9/2007 Physician Belgium
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Female 163 lb 2/16/2007 Physician Germany
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/28/2005 Female 2/16/2007 Physician Belgium
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/18/2005 Female 2/21/2007 Physician Belgium
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 9/15/2003 67 Female 3/5/2007 Physician Australia
Primary
Concomitant
Pulmonary Oedema Hospitalization 12/1/2006 Female 185 lb 3/8/2007 Physician United Kingdom
Primary
Concomitant
Respiratory Tract Infection Hospitalization 7/1/2006 76 Female 3/8/2007 Physician Greece
Primary
Secondary
Concomitant
Joint Swelling Hospitalization 3/14/2006 Female 126 lb 3/8/2007 Consumer United Kingdom
Primary
Concomitant
Joint Swelling Hospitalization 5/12/2006 Female 119 lb 3/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hemiplegia Hospitalization 10/1/2005 Female 3/20/2007 Physician Costa Rica
Primary
Concomitant
Hepatitis Hospitalization 12/23/2006 Female 150 lb 3/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lymphocytosis Hospitalization 11/17/2005 Female 3/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Tract Infection Hospitalization 7/1/2006 76 Female 4/2/2007 Physician Greece
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 6/17/2006 Female 161 lb 4/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sigmoiditis Other Serious 9/29/2006 Female 4/4/2007 Physician Belgium
Primary
Concomitant
Sigmoiditis Other Serious 9/29/2006 Female 4/16/2007 Physician Belgium
Primary
Concomitant
Respiratory Tract Infection Hospitalization 7/1/2006 76 Female 4/20/2007 Physician Greece
Primary
Secondary
Concomitant
Urinary Retention Other Serious 8/15/2006 Male 223 lb 4/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/5/2007 Female 99 lb 4/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 4/12/2006 Male 161 lb 4/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 3/15/2007 75 Female 4/27/2007 Physician Greece
Primary
Concomitant
Syncope Hospitalization 4/12/2006 Female 143 lb 5/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/1/2006 81 Male 5/18/2007 Physician Greece
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 12/1/2003 Female 121 lb 5/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Other Serious 8/15/2006 Male 223 lb 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/1/2006 81 Male 5/31/2007 Physician Greece
Primary
Secondary
Concomitant
Syncope Hospitalization 4/12/2006 Female 143 lb 6/1/2007 Physician United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 Female 6/4/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Aortic Aneurysm Rupture Life Threatening 3/12/2007 Male 225 lb 6/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Aortic Aneurysm Rupture Life Threatening 3/12/2007 Male 225 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Ischaemia Death Male 157 lb 7/20/2007 United Kingdom
Primary
Concomitant
Joint Swelling Hospitalization 5/12/2006 Female 119 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Joint Swelling Hospitalization 3/14/2006 Female 126 lb 7/25/2007 Consumer United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 6/18/2007 Female 130 lb 7/31/2007 United Kingdom
Primary
Concomitant
Staphylococcal Infection Life Threatening 3/1/2007 68 Female 146 lb 8/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Spinal Decompression Other Serious 1/28/2007 Female 84 lb 8/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Life Threatening 3/1/2007 68 Female 146 lb 8/9/2007
Primary
Secondary
Concomitant
Acute Respiratory Failure Other Serious 7/31/2007 Female 8/13/2007 Greece
Primary
Concomitant
Oophorectomy Other Serious 3/1/2007 70 Female 8/13/2007 Germany
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2006 Male 142 lb 8/17/2007 Germany
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 4/1/2007 Female 140 lb 8/22/2007 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data