Leflunomide combined with Meloxicam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Other Serious 9/5/2005 Male 1/23/2006 Czech Republic
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 8/1/2003 Female 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Knee Arthroplasty Other Serious Male 138 lb 5/2/2006 Consumer Canada
Primary
Concomitant
Meniscus Operation Hospitalization 3/27/2006 58 Female 5/11/2006 Physician Austria
Primary
Concomitant
Pancreatic Carcinoma Life Threatening 5/19/2006 65 Female 8/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pustular Psoriasis Other Serious 7/1/2006 Female 9/15/2006 Physician Belgium
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Male 174 lb 11/3/2006 Physician United States
Primary
Secondary
Concomitant
Surgery Death Female 207 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Occlusion Other Serious 10/31/2006 Female 123 lb 11/13/2006 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Other Serious 10/31/2006 Female 123 lb 11/13/2006 Consumer United States
Primary
Concomitant
Skin Exfoliation Other Serious 7/1/2006 Female 11/22/2006 Physician Belgium
Primary
Secondary
Concomitant
Rectal Haemorrhage Death 9/13/2006 Female 163 lb 12/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Exfoliation Other Serious 7/1/2006 Female 12/13/2006 Physician Belgium
Primary
Secondary
Concomitant
Fatigue Hospitalization 11/1/2006 Female 134 lb 12/15/2006 Consumer Brazil
Primary
Concomitant
Weight Decreased Other Serious 8/1/2003 65 Female 12/18/2006 United States
Primary
Concomitant
Surgery Death 7/26/2006 Female 207 lb 1/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Injection Site Swelling Other Serious 11/1/2006 Male 212 lb 1/19/2007 Physician United States
Primary
Concomitant
Rectal Haemorrhage Death 9/13/2006 Female 163 lb 1/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oesophageal Neoplasm Other Serious 9/6/2006 71 Male 154 lb 2/12/2007 Physician Belgium
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/5/2006 Female 178 lb 3/23/2007 Physician United States
Primary
Concomitant
Lymphocytosis Hospitalization 11/17/2005 Female 3/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lung Neoplasm Other Serious 6/1/2006 82 Female 190 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Venous Pressure Jugular Increased Other Serious 3/15/2006 Female 146 lb 6/19/2007 Physician United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2004 Female 168 lb 6/26/2007 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 3/23/2007 Male 175 lb 6/29/2007 Physician United States
Primary
Concomitant
Hospitalisation Hospitalization Female 7/13/2007 Canada
Primary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/2004 Female 168 lb 7/26/2007 Consumer United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 6/3/2007 Female 126 lb 8/17/2007 United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 4/1/2007 Female 140 lb 8/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 7/7/2007 Female 155 lb 8/29/2007 Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 12/15/2006 Female 170 lb 9/10/2007 United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 63 Female 150 lb 10/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 7/13/2007 Female 11/21/2007 Belgium
Primary
Concomitant
Injection Site Pain 6/1/2005 Female 123 lb 12/14/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 6/1/2007 Male 228 lb 12/14/2007 Consumer United States
Primary
Concomitant
Swelling 11/8/2007 Female 12/14/2007 United States
Primary
Concomitant
Injection Site Pain Other Serious 1/1/2005 Female 150 lb 12/15/2007 Physician United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 2/21/2007 Female 139 lb 12/27/2007 United Kingdom
Primary
Concomitant
Intestinal Obstruction Other Serious 6/3/2007 Female 126 lb 1/21/2008 United Kingdom
Primary
Concomitant
Weight Increased Other Serious 12/5/2005 Female 133 lb 3/14/2008 United States
Primary
Concomitant
Neck Pain 8/1/2007 Female 145 lb 3/15/2008 Consumer United States
Primary
Concomitant
Knee Arthroplasty Other Serious 1/7/2008 24 Female 3/19/2008 Brazil
Primary
Concomitant
Femoral Neck Fracture Hospitalization 2/1/2008 62 Female 5/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 Male 5/21/2008 Germany
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/1/2007 Male 6/6/2008 Germany
Primary
Secondary
Concomitant
Urticaria 1/31/2008 Female 120 lb 6/12/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection 3/27/2007 Female 180 lb 6/12/2008 United States
Primary
Concomitant
Hepatic Enzyme Increased 4/10/2008 Female 140 lb 6/12/2008 Consumer United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis 11/1/2007 Female 195 lb 6/13/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 Male 8/8/2008 Germany
Primary
Secondary
Concomitant
Spinal Fusion Surgery Other Serious 1/1/2006 152 lb 8/11/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 Male 8/19/2008 Germany
Primary
Secondary
Concomitant
Syncope Other Serious 4/29/2008 Female 154 lb 8/21/2008 United Kingdom
Primary
Concomitant
Pneumonia Other Serious 1/24/2007 60 Female 190 lb 9/10/2008 Physician Finland
Primary
Secondary
Concomitant
Pain In Extremity 5/24/2008 Female 150 lb 9/12/2008 United States
Primary
Concomitant
Rash Pruritic 6/7/2008 Female 152 lb 9/12/2008 United States
Primary
Concomitant
Urticaria 7/1/2008 Female 200 lb 9/13/2008 United States
Primary
Concomitant
Surgery Hospitalization 1/1/2008 62 Female 9/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/1/2006 Male 321 lb 10/2/2008 Physician United States
Primary
Concomitant
Blood Glucose Increased Other Serious 9/29/2008 64 Male 220 lb 10/7/2008 Consumer United States
Primary
Concomitant
Encephalitis Hospitalization 5/13/2008 Female 170 lb 10/8/2008 United Kingdom
Primary
Concomitant
Rectal Haemorrhage Death 9/13/2006 Female 163 lb 10/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Death 9/13/2006 Female 163 lb 10/20/2008 United Kingdom
Primary
Concomitant
Nerve Compression Hospitalization 11/4/2004 Female 176 lb 12/2/2008 United Kingdom
Primary
Concomitant
Urticaria 8/28/2008 Female 12/12/2008 United States
Primary
Concomitant
Musculoskeletal Chest Pain 10/16/2008 Female 12/12/2008 United States
Primary
Concomitant
Psoriasis 10/16/2008 Female 12/12/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2003 65 Female 12/16/2008 United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Female 136 lb 12/17/2008
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/29/2008 Male 194 lb 1/12/2009 United Kingdom
Primary
Concomitant
Synovitis Hospitalization 5/8/2008 Female 170 lb 2/20/2009 United Kingdom
Primary
Secondary
Concomitant
Synovitis Hospitalization 5/8/2008 Female 170 lb 2/25/2009 United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis 11/1/2007 Female 195 lb 3/13/2009 Physician United States
Primary
Concomitant
Crohn's Disease Other Serious 1/1/2009 52 Female 5/15/2009 Consumer United Kingdom
Primary
Concomitant
Rash 4/13/2009 Female 132 lb 6/12/2009 United States
Primary
Concomitant
Tendon Rupture Other Serious Female 115 lb 6/15/2009 Brazil
Primary
Concomitant
Tuberculosis Other Serious 1/1/2009 Male 7/9/2009 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Tuberculosis Other Serious 1/1/2009 Male 148 lb 7/15/2009 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Loss Of Consciousness Hospitalization 1/19/2005 Female 126 lb 7/17/2009 United Kingdom
Primary
Concomitant
Malaise Hospitalization 5/17/2006 Female 146 lb 7/21/2009 United Kingdom
Primary
Concomitant
Tuberculosis Other Serious 1/1/2009 Male 148 lb 7/31/2009 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Tuberculosis Of Central Nervous System Hospitalization 5/8/2008 Female 170 lb 7/31/2009 United Kingdom
Primary
Secondary
Concomitant
Lumbar Radiculopathy Death 11/13/2008 Male 174 lb 8/10/2009 Physician United States
Primary
Concomitant
Pain Death 58 Female 7/30/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Death 58 Female 8/14/2009 Lawyer United States
Primary
Concomitant
Neck Pain 8/1/2007 Female 145 lb 9/12/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 4/10/2008 Female 140 lb 9/12/2009 Consumer United States
Primary
Secondary
Concomitant
Headache 6/11/2009 Female 9/19/2009 Consumer United States
Primary
Concomitant
Rhinorrhoea 7/12/2009 Female 162 lb 9/19/2009 United States
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 5/17/2006 Female 146 lb 10/7/2009 United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 55 Female 114 lb 11/24/2009 Physician Canada
Primary
Concomitant
Tendon Rupture Other Serious Female 101 lb 12/4/2009 Brazil
Primary
Concomitant
Loss Of Consciousness Other Serious 11/8/2009 74 Female 12/8/2009 Pharmacist South Africa
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 74 Female 12/10/2009 Pharmacist South Africa
Primary
Secondary
Concomitant
Rhinorrhoea 7/12/2009 Female 162 lb 12/10/2009 Consumer United States
Primary
Secondary
Concomitant
Hyponatraemia Disability 11/28/2009 79 Female 12/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Depression Other Serious 74 Female 12/17/2009 Pharmacist South Africa
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 11/28/2009 79 Female 12/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unevaluable Event Death 58 Female 1/12/2010 United States
Primary
Concomitant
Opportunistic Infection Other Serious 11/2/2009 55 Female 114 lb 1/22/2010 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 60 1/28/2010 Physician Korea, Republic Of
Primary
Concomitant
Pain Death 58 Female 1/22/2010 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 4/7/2009 Female 2/3/2010 United Kingdom
Primary
Concomitant
Opportunistic Infection Other Serious 11/2/2009 55 Female 114 lb 2/4/2010 Physician Canada
Primary
Concomitant
Tendon Rupture Other Serious 12/25/2008 Female 108 lb 2/4/2010 Brazil
Primary
Concomitant
Pulmonary Embolism Other Serious 3/25/2009 Female 3/22/2010 United Kingdom
Primary
Concomitant
Myocardial Infarction Death 2/19/2010 67 Female 130 lb 4/16/2010 Canada
Primary
Concomitant
Myocardial Infarction Death 2/19/2010 67 Female 130 lb 4/27/2010 Canada
Primary
Concomitant
Tendon Rupture Other Serious 12/25/2008 62 Female 108 lb 5/7/2010 Brazil
Primary
Concomitant
Tinnitus Other Serious 2/22/2010 63 Female 141 lb 5/19/2010 Physician United States
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 12/25/2008 62 Female 108 lb 5/21/2010 Brazil
Primary
Secondary
Concomitant
Unevaluable Event Death 58 Female 5/26/2010 Lawyer United States
Primary
Concomitant
Myocardial Infarction Death 2/19/2010 67 Female 130 lb 6/7/2010 Consumer Canada
Primary
Concomitant
Urinary Tract Infection Death Female 146 lb 6/17/2010 Consumer United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Death 58 Female 7/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 1/1/2010 71 Female 213 lb 9/2/2010 Consumer United States
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 1/1/2010 71 Female 213 lb 9/16/2010 Consumer United States
Primary
Secondary
Concomitant
Urticaria Other Serious 9/1/2008 10/21/2010 Physician United States
Primary
Concomitant
Sepsis Death 6/5/2010 68 Female 11/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 2/19/2010 67 Female 130 lb 11/19/2010 Physician Canada
Primary
Concomitant
Pulmonary Fibrosis Death 3/19/2010 53 Female 128 lb 11/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death 2/19/2010 67 Female 130 lb 12/1/2010 Physician Canada
Primary
Concomitant
Myocardial Infarction Death 2/19/2010 67 Female 130 lb 12/1/2010 Physician Canada
Primary
Concomitant
Pulmonary Fibrosis Death 3/19/2010 53 Female 128 lb 12/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Injection Site Reaction 12/26/2009 12/21/2010 Consumer United States
Primary
Concomitant
Pruritus Generalised 7/1/2010 12/23/2010 Consumer United States
Primary
Concomitant
Eye Haemorrhage Hospitalization 1/14/2011 37 Female 1/24/2011 Consumer Colombia
Primary
Concomitant
Incorrect Dose Administered 3/12/2010 56 Female 235 lb 1/28/2011 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 12/1/2009 48 Female 205 lb 2/1/2011 Consumer United States
Primary
Concomitant
Eye Haemorrhage Hospitalization 1/14/2011 37 Female 2/10/2011 Other Health Professional Colombia
Primary
Concomitant
Circulatory Collapse Hospitalization 1/1/2009 66 Female 119 lb 2/14/2011 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 48 Male 2/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Life Threatening 77 Female 88 lb United States
Primary
Concomitant
Blindness Unilateral Hospitalization 6/27/2011 66 Female 88 lb 7/12/2011 Physician Colombia
Primary
Concomitant
Optic Neuritis Hospitalization 6/27/2011 66 Female 88 lb 7/29/2011 Physician Colombia
Primary
Concomitant
Dyspnoea Hospitalization 6/25/2011 71 Female 132 lb 9/7/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Nasopharyngitis Other Serious 6/30/2011 53 Female 93 lb 9/20/2011 Consumer United Kingdom
Primary
Concomitant
Arthralgia Hospitalization 1/14/2011 37 Female 10/4/2011 Consumer Colombia
Primary
Concomitant
Condition Aggravated Other Serious 10/1/2010 54 Female 140 lb 10/19/2011 Physician Canada
Primary
Concomitant
Abasia Other Serious 5/1/2011 57 Female 10/20/2011 Consumer Colombia
Primary
Concomitant
Chills 10/29/2010 Female 10/27/2011 United States
Primary
Concomitant
Psoriasis Other Serious 7/12/2011 Female 251 lb 11/2/2011 Physician Germany
Primary
Concomitant
Cardiomyopathy Hospitalization 5/1/2011 64 Female 258 lb 11/22/2011 Physician United States
Primary
Concomitant
Psoriasis Other Serious 7/12/2011 Female 251 lb 11/29/2011 Physician Germany
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/1/2010 48 Male 227 lb 12/7/2011 Consumer Canada
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 5/1/2011 64 Female 258 lb 12/28/2011 Physician United States
Primary
Concomitant
Injection Site Pain Other Serious 1/1/2011 57 Female 1/10/2012 Other Health Professional Colombia
Primary
Concomitant
Rash 11/1/2010 37 Female 100 lb 1/27/2012 Consumer United States
Primary
Concomitant
Rash Pruritic 3/16/2011 50 Male 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Nodule 2/1/2011 63 Female 138 lb 1/28/2012 Consumer United States
Primary
Concomitant

Drug Data