Leflunomide combined with Lisinopril

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteitis Hospitalization 8/23/2004 Female 163 lb 2/15/2006 Netherlands
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 11/30/2004 Male 2/22/2006 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/30/2005 Female 128 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteomyelitis Hospitalization 1/1/2006 Female 163 lb 3/16/2006 Netherlands
Primary
Concomitant
Osteomyelitis Hospitalization 1/1/2006 Female 163 lb 3/16/2006 Netherlands
Primary
Concomitant
Pneumonia Hospitalization 12/30/2005 Female 128 lb 4/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteitis Hospitalization 8/23/2004 Female 163 lb 4/11/2006 Netherlands
Primary
Concomitant
Toe Amputation Hospitalization 8/23/2004 Female 163 lb 4/11/2006 Netherlands
Primary
Concomitant
Skin Disorder Hospitalization 1/1/2006 Female 163 lb 4/12/2006 Netherlands
Primary
Concomitant
Sepsis Hospitalization 12/30/2005 Female 128 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteomyelitis Hospitalization 1/1/2006 Female 163 lb 5/19/2006 Netherlands
Primary
Concomitant
Sepsis Hospitalization 12/30/2005 Female 128 lb 6/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 12/25/2005 Female 128 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 61 Female 9/25/2006
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 1/1/2006 Female 163 lb 10/18/2006 Netherlands
Primary
Concomitant
Osteomyelitis Hospitalization 1/1/2006 Female 163 lb 11/16/2006 Netherlands
Primary
Concomitant
Osteomyelitis Hospitalization 1/1/2006 Female 163 lb 11/20/2006 Netherlands
Primary
Concomitant
Heart Rate Increased 1/5/2005 74 Male 11/28/2006 Consumer United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 11/1/2006 Female 134 lb 12/15/2006 Consumer Brazil
Primary
Concomitant
Pyrexia Other Serious 12/3/2006 Female 350 lb 1/17/2007 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 9/26/2006 Male 212 lb 2/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Gallbladder Operation Other Serious Male 190 lb 4/4/2007 Consumer Canada
Primary
Concomitant
Pancreatic Carcinoma Other Serious Female 137 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Multi-organ Failure Death 1/1/2006 Male 6/22/2007 Physician Hong Kong
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 6/9/2007 Female 132 lb 6/29/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2007 Female 132 lb 8/23/2007 Other Health Professional United States
Primary
Concomitant
Multi-organ Failure Death 1/1/2006 Male 8/30/2007 Physician Hong Kong
Primary
Concomitant
Angioedema Other Serious 9/4/2007 77 Female 202 lb 10/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2007 76 Female 197 lb 10/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 5/6/2007 Male 154 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious Male 121 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wrist Fracture Other Serious 2/1/2000 67 Female 93 lb 11/28/2007 United States
Primary
Concomitant
Mitral Valve Prolapse Other Serious 8/21/2007 Female 1/21/2008 Belgium
Primary
Concomitant
Hypothermia Other Serious 10/16/2007 Male 121 lb 2/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Injection Site Pain 1/1/2007 Female 168 lb 3/14/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 12/20/2007 Female 120 lb 3/14/2008 Consumer United States
Primary
Concomitant
Sinusitis 12/28/2007 Female 115 lb 3/14/2008 Consumer United States
Primary
Concomitant
Rash Vesicular Hospitalization 4/26/2006 Female 116 lb 3/25/2008 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/16/2007 67 Female 184 lb 5/14/2008 Greece
Primary
Concomitant
Prostate Cancer Recurrent Other Serious 1/1/2005 Male 178 lb 6/12/2008 United States
Primary
Concomitant
Psoriatic Arthropathy 8/1/2006 32 Male 154 lb 6/13/2008 Physician United States
Primary
Concomitant
Pain 5/1/2008 Female 150 lb 6/13/2008 Consumer United States
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 1/1/2005 Male 178 lb 6/18/2008 United States
Primary
Concomitant
Wrist Fracture Other Serious 2/1/2000 67 Female 93 lb 7/3/2008 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 6/19/2006 Male 161 lb 7/21/2008 United Kingdom
Primary
Concomitant
Rash Vesicular Hospitalization 4/26/2006 Female 116 lb 8/5/2008 Other Health Professional Canada
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 12/20/2007 Male 8/8/2008 Physician United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection 12/20/2007 Male 8/14/2008 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 12/1/2006 Male 321 lb 8/19/2008 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 2/1/2000 67 Female 93 lb 8/21/2008 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 2/1/2000 67 Female 93 lb 8/29/2008 Physician United States
Primary
Concomitant
Psoriatic Arthropathy 8/1/2006 Male 154 lb 9/12/2008 Physician United States
Primary
Concomitant
Sneezing 3/19/2008 Female 123 lb 9/12/2008 United States
Primary
Concomitant
Blood Pressure Increased 6/10/2008 Male 175 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Pain 6/14/2008 Female 223 lb 9/12/2008 United States
Primary
Concomitant
Nasopharyngitis 7/30/2008 Female 225 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 5/1/2008 Female 131 lb 9/13/2008 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/23/2007 44 Male 9/25/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2008 Female 9/22/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2006 Male 321 lb 10/2/2008 Physician United States
Primary
Concomitant
Sarcoidosis Other Serious 1/1/2006 Female 10/22/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 54 Male 100 lb 11/26/2008 United States
Primary
Concomitant
Injection Site Erythema 10/18/2008 Male 215 lb 12/12/2008 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 140 lb 12/11/2008 Physician United States
Primary
Concomitant
Respiratory Tract Congestion Hospitalization 11/17/2008 Male 165 lb 12/17/2008 United States
Primary
Concomitant
Swelling Face 1/1/2008 56 Male 12/31/2008 Consumer United States
Primary
Concomitant
Renal Failure Death 1/1/2009 Female 1/22/2009 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 2/1/2000 67 Female 93 lb 3/10/2009 Physician United States
Primary
Concomitant
Alopecia 10/1/2008 Female 3/14/2009 Consumer United States
Primary
Secondary
Concomitant
Musculoskeletal Stiffness 1/1/2009 Female 3/14/2009 United States
Primary
Concomitant
Wrist Fracture Other Serious 2/1/2000 67 Female 93 lb 4/8/2009 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 2/1/2000 67 Female 93 lb 4/30/2009 Physician United States
Primary
Concomitant
Prostate Cancer Other Serious 7/11/2007 69 Male 170 lb 5/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Blood Pressure Increased 1/5/2009 Male 200 lb 6/11/2009 Consumer United States
Primary
Concomitant
Urticaria 4/8/2009 Female 178 lb 6/15/2009 Physician United States
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 6/10/2009 80 Female 95 lb 6/18/2009 Consumer United States
Primary
Concomitant
Pain In Jaw Other Serious 6/11/2009 Female 136 lb 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 6/11/2009 Female 136 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Lumbar Radiculopathy Death 11/13/2008 Male 174 lb 8/10/2009 Physician United States
Primary
Concomitant
Incorrect Dose Administered 9/17/2006 Male 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 12/20/2007 Female 120 lb 9/12/2009 Consumer United States
Primary
Concomitant
Pain 5/1/2008 Female 150 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 6/14/2008 Female 223 lb 9/12/2009 United States
Primary
Concomitant
Injection Site Pain 5/1/2008 Female 131 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vomiting Female 270 lb 9/19/2009 United States
Primary
Concomitant
Wrist Fracture Other Serious 2/1/2000 67 Female 93 lb 10/2/2009 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 2/1/2000 67 Female 93 lb 10/6/2009 Physician United States
Primary
Concomitant
Pain In Jaw Other Serious 6/11/2009 Female 136 lb 11/2/2009 Physician United States
Primary
Secondary
Concomitant
Stress 1/1/2007 Female 190 lb 1/30/2010 Other Health Professional
Primary
Concomitant
Osteonecrosis Other Serious 11/11/2009 71 Female 1/29/2010 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 1/1/2010 52 Male 400 lb 6/2/2010 Consumer United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 11/1/2006 70 Female 98 lb 6/16/2010 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Hospitalization 11/1/2006 70 Female 98 lb 7/8/2010 Consumer United States
Primary
Concomitant
Penile Pain Male 196 lb 7/31/2010 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 7/1/2010 74 Female 7/30/2010 Consumer United States
Primary
Concomitant
Death Death 66 Male 192 lb 8/13/2010 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 7/1/2010 74 Female 8/27/2010 Consumer United States
Primary
Concomitant
Wrist Fracture Other Serious 2/1/2000 67 Female 93 lb 9/10/2010 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 6/17/2010 62 Female 160 lb 9/22/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 10/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/1/2010 74 Female 10/19/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 10/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pharyngeal Disorder 74 Female 10/13/2010 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 11/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 1/1/2002 75 Female 138 lb 11/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash 12/13/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 12/14/2010 Physician United States
Primary
Concomitant
Injection Site Haematoma 11/18/2009 12/14/2010 Consumer United States
Primary
Concomitant
Injection Site Pain 12/19/2010 Consumer United States
Primary
Concomitant
Paraesthesia 12/19/2010 Consumer United States
Primary
Concomitant
Sinusitis 1/1/2009 12/20/2010 Physician United States
Primary
Concomitant
Deafness Other Serious 1/1/2010 49 Male 210 lb 1/20/2011 Consumer United States
Primary
Concomitant
Ingrowing Nail Other Serious 12/15/2010 46 Female 1/24/2011 Consumer United States
Primary
Concomitant
Localised Infection Hospitalization 12/1/2009 77 Female 128 lb 1/28/2011 Physician United States
Primary
Concomitant
Injection Site Pain 4/6/2010 62 Male 260 lb 1/28/2011 United States
Primary
Concomitant
Pain In Jaw 10/1/2009 56 Male 180 lb 1/29/2011 Physician United States
Primary
Concomitant
Liquid Product Physical Issue 7/18/2010 68 Female 1/29/2011 Consumer United States
Primary
Concomitant
Urinary Tract Infection 3/1/2010 53 Female 160 lb 1/29/2011 Consumer United States
Primary
Concomitant
Pyrexia 1/1/2006 65 Female 1/29/2011 Consumer United States
Primary
Concomitant
Chest Pain Other Serious 1/1/2009 68 Female 1/30/2011 Other Health Professional United States
Primary
Concomitant
Coronary Artery Occlusion Other Serious 1/1/2008 57 Female 2/4/2011 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Other Serious 1/1/2008 57 Female 2/9/2011 Consumer United States
Primary
Concomitant
No Adverse Event 11/7/2010 70 Female 175 lb 2/18/2011 Consumer United States
Primary
Concomitant
Vomiting Other Serious Female 2/24/2011 Consumer United States
Primary
Concomitant
Arrhythmia Other Serious 1/1/2008 57 Female 3/3/2011 Physician United States
Primary
Concomitant
Insomnia 4/1/2010 69 Female 3/25/2011 Consumer United States
Primary
Concomitant
Nausea Other Serious Female 99 lb 4/6/2011 Consumer United States
Primary
Concomitant
Hypoglycaemia Other Serious 3/1/2011 66 Female 102 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Arthritis 9/1/2009 Female 180 lb 5/13/2011 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 5/13/2011 43 Female 258 lb 6/22/2011 Consumer United States
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 5/5/2011 57 Female 231 lb 6/28/2011 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 5/27/2011 62 Male 7/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 5/27/2011 62 Male 166 lb 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Toxicity Hospitalization 5/27/2011 62 Male 166 lb 6/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 5/27/2011 62 Male 7/1/2011 United Kingdom
Primary
Concomitant
Pancytopenia Hospitalization 5/27/2011 62 Male 166 lb 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 5/27/2011 62 Male 166 lb 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 5/27/2011 62 Male 166 lb 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 5/27/2011 62 Male 166 lb 7/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 62 Male 166 lb 7/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 62 Male 7/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 62 Male 7/29/2011 United Kingdom
Primary
Concomitant
Death Hospitalization 1/1/2011 53 Female 261 lb 9/2/2011 Consumer United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 1/1/2002 66 Female 122 lb 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Osteoporosis Other Serious 1/1/2011 43 Male 10/25/2011 Consumer United States
Primary
Concomitant
Cough Female 165 lb 10/29/2011 Other Health Professional United States
Primary
Concomitant
Arthritis Other Serious 7/1/2011 49 Male 204 lb 11/23/2011 Physician United States
Primary
Concomitant
Hypocalcaemia Hospitalization 11/19/2011 73 Female 12/15/2011 Physician Netherlands
Primary
Concomitant

Drug Data