Lasix combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Hospitalization 1/23/2006 Female 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Other Serious 61 Female 227 lb 2/7/2006 Physician South Africa
Primary
Concomitant
Pneumonia Death 12/25/2005 57 Male 235 lb 2/14/2006 Other Health Professional United States
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 11/9/2004 56 Female 187 lb 3/7/2006 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 10/27/2005 74 Female 3/15/2006 Other Health Professional France
Primary
Concomitant
Psoriasis 8/1/2005 48 Female 276 lb 1/20/2006 Consumer United States
Primary
Concomitant
Prothrombin Time Shortened Hospitalization 1/8/2006 73 Female 3/30/2006 Other Health Professional Italy
Primary
Concomitant
Gastrointestinal Haemorrhage Death 4/4/2006 81 Male 4/20/2006 Consumer United States
Primary
Concomitant
Prothrombin Time Shortened Hospitalization 1/8/2006 73 Female 4/24/2006 Other Health Professional Italy
Primary
Concomitant
Blood Glucose Increased Other Serious 69 Female 4/26/2006 Pharmacist Canada
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/5/2006 80 Female 5/3/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 11/9/2004 56 Female 187 lb 5/3/2006 Physician United States
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Death 1/1/2004 38 Male 284 lb 5/10/2006 Lawyer United States
Primary
Concomitant
Pleural Effusion Hospitalization 8/1/2005 78 Male 202 lb 7/21/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 11/22/2005 80 Male 8/1/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Death 2/16/2006 70 Female 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 7/17/2006 47 Female 8/10/2006 Consumer United States
Primary
Concomitant
Parosmia 54 Female 12/14/2006 United States
Primary
Concomitant
Granulocytopenia Life Threatening 12/12/2006 67 Male 1/2/2007 Germany
Primary
Concomitant
Neoplasm Other Serious 1/1/2004 Male 180 lb 1/19/2007 Consumer United States
Primary
Concomitant
Muscular Weakness Disability 12/1/2006 70 Female 2/22/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/25/2007 43 Male 210 lb 3/15/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/25/2007 43 Male 210 lb 3/28/2007 Consumer United States
Primary
Concomitant
Muscular Weakness Disability 12/1/2006 70 Female 4/4/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/25/2007 43 Male 210 lb 5/8/2007 Consumer United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 1/31/2007 60 Female 6/11/2007 Physician Australia
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 10/1/2006 93 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 12/29/2006 54 Female 277 lb 4/26/2007 United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 8/1/2007 Male 220 lb 11/13/2007 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 10/1/2007 Female 11/12/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2007 68 Female 11/13/2007 Consumer United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 10/1/2006 93 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Gastrointestinal Ulcer Other Serious 1/1/2008 81 Female 130 lb 10/17/2008 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Ulcer Other Serious 1/1/2008 81 Female 130 lb 10/20/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/21/2008 71 Male 156 lb 10/21/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/17/2008 Male 304 lb 10/21/2008 United States
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Life Threatening 8/16/2008 65 Female 10/17/2008 Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Life Threatening 8/15/2008 65 Female 10/29/2008 Japan
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2008 Male 203 lb 3/31/2009 Physician United States
Primary
Concomitant
Renal Cell Carcinoma Other Serious 12/12/2008 Female 234 lb 4/24/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 40 Female 166 lb 5/14/2009 United States
Primary
Concomitant
Vision Blurred 12/15/2008 61 Female 5/15/2009 United States
Primary
Concomitant
Radiation Skin Injury 5/12/2009 50 Female 229 lb 5/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 12/12/2008 Female 234 lb 5/28/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 5/26/2009 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/27/2009 Female 6/2/2009 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 11/1/2000 55 Male 241 lb 6/4/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2007 Female 6/4/2009 Consumer
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/11/2007 51 Male 196 lb 6/5/2009 United States
Primary
Concomitant
Transfusion Hospitalization 5/6/2009 Male 6/5/2009 Physician United States
Primary
Secondary
Concomitant
Injection Site Haemorrhage 1/12/2008 Male 6/11/2009 Consumer
Primary
Concomitant
Weight Increased Hospitalization 10/1/2008 Female 265 lb 6/12/2009 United States
Primary
Concomitant
Pain In Extremity 2/1/2009 Male 240 lb 6/12/2009 United States
Primary
Concomitant
Injection Site Haemorrhage 1/12/2008 Male 6/12/2009 Consumer
Primary
Concomitant
Rheumatoid Arthritis 1/1/2005 Female 155 lb 6/15/2009 Other Health Professional United States
Primary
Concomitant
Photosensitivity Reaction 4/1/2009 Male 6/15/2009 Physician United States
Primary
Concomitant
Malaise Life Threatening 6/21/2009 83 Male 139 lb 7/20/2009 Other Health Professional Japan
Primary
Concomitant
Respiratory Failure Hospitalization 4/1/2009 Female 8/6/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 48 Female 172 lb 8/7/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 42 Female 8/26/2009 United States
Primary
Concomitant
Purpura Other Serious 7/7/2009 75 Male 9/9/2009 Other Health Professional
Primary
Secondary
Concomitant
Hyperinsulinaemia 10/26/2004 43 Male 297 lb 9/23/2009 United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 5/1/2004 46 Female 226 lb 9/30/2009 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 12/1/2008 52 Female 9/21/2009 Lawyer United States
Primary
Concomitant
Hiccups 8/24/2009 73 Male 216 lb 10/1/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 9/25/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 4/15/2008 60 Female 250 lb 9/24/2009 United States
Primary
Concomitant
Vitamin D Deficiency Hospitalization 72 Female 9/23/2009 United States
Primary
Concomitant
Tricuspid Valve Disease Hospitalization 6/5/2007 44 Male 213 lb 9/25/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 62 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 50 Male 354 lb 9/22/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 60 Female 9/29/2009 United States
Primary
Concomitant
Tremor 5/25/2009 53 Female 136 lb 10/12/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/7/2003 36 Male 222 lb 10/14/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 9/1/2009 Female 10/7/2009 Consumer United States
Primary
Concomitant
Drug Ineffective 2/1/2009 Female 10/15/2009 Consumer
Primary
Concomitant
Myocardial Infarction Hospitalization 3/1/2007 65 Male 211 lb 10/15/2009 Pharmacist United States
Primary
Concomitant
Chest Discomfort Death 75 Female 12/18/2009 Canada
Primary
Secondary
High Density Lipoprotein Decreased 5/26/2009 58 Female 1/4/2010 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Life Threatening 5/3/2008 86 Female 156 lb 1/5/2010 Pharmacist United States
Primary
Concomitant
Injury Other Serious Female 1/13/2010 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 12/28/2009 United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/6/2010 46 Male 476 lb 1/8/2010 Pharmacist United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 1/14/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2009 Male 183 lb 1/22/2010 Pharmacist United States
Primary
Concomitant
Interacting
Urinary Tract Obstruction Hospitalization 76 Male 1/22/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious 8/1/2009 Female 2/18/2010 Physician Canada
Primary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Wheezing Hospitalization 79 Male 2/5/2010 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Nausea Hospitalization 76 Female 2/26/2010 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 350 lb 2/25/2010 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2010 76 Female 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 4/1/2009 Female 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2010 76 Female 3/2/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 12/4/2007 71 Female 121 lb 3/3/2010 Lawyer United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 11/16/2009 Male 3/3/2010 Consumer Brazil
Primary
Concomitant
Renal Failure Other Serious 10/1/2007 61 Male 214 lb 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2008 Male 162 lb 3/8/2010 Physician United States
Primary
Concomitant
Nausea 2/1/2010 66 Female 174 lb 3/8/2010 Consumer United States
Primary
Concomitant
Sciatica Other Serious Female 3/9/2010 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 68 Female 216 lb 3/17/2010 Pharmacist United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 3/1/2007 Female 242 lb 3/16/2010 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2006 Female 3/18/2010 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 10/1/2006 59 Male 297 lb 3/17/2010 Physician United States
Primary
Concomitant
Renal Disorder Other Serious 11/1/2006 Male 250 lb 3/17/2010 Physician United States
Primary
Concomitant
Pancreatitis Relapsing Other Serious 6/1/2008 Male 280 lb 3/17/2010 Physician United States
Primary
Concomitant
Renal Injury Hospitalization 12/1/2007 Male 258 lb 3/17/2010 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/29/2010 Female 210 lb 3/22/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 10/1/2007 68 Male 159 lb 3/22/2010 Lawyer United States
Primary
Concomitant
Renal Injury Hospitalization Female 3/22/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Male 179 lb 3/22/2010 Consumer United States
Primary
Concomitant
Toothache Other Serious 11/1/2009 70 Female 149 lb 4/26/2010 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 3/23/2010 62 Male 203 lb 5/10/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/28/2010 United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 77 Female 155 lb 5/11/2010 Pharmacist United States
Primary
Concomitant
Skin Ulcer Hospitalization 1/29/2010 64 Male 160 lb 5/12/2010 Physician United States
Primary
Concomitant
Product Substitution Issue Other Serious 1/1/2010 Female 5/10/2010 Pharmacist United States
Primary
Concomitant
Sinus Arrhythmia Hospitalization 3/24/2010 87 Male 5/17/2010 Other Health Professional France
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 77 Female 155 lb 5/19/2010 Pharmacist United States
Primary
Concomitant
Dyspnoea Hospitalization Male 289 lb 5/19/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 5/11/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 89 Male 5/20/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 4/28/2010 69 Female 187 lb 5/20/2010 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 12/1/2008 64 Male 5/21/2010 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/24/2010 64 Female 211 lb 5/21/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2009 67 Female 184 lb 5/26/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 10/20/2009 66 Male 300 lb 5/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Catheterisation Cardiac Abnormal Hospitalization 5/13/2010 59 Female 301 lb 5/27/2010 Consumer United States
Primary
Secondary
Concomitant
Transplant Rejection Life Threatening 11/1/2009 53 Female 5/27/2010 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 49 Female 304 lb 5/28/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/26/2010 -1 Male 154 lb 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 12/12/2008 60 Female 234 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Vascular Insufficiency Disability 8/1/2009 52 Male 306 lb 7/2/2010 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 5/26/2010 70 Male 154 lb 7/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vascular Insufficiency Disability 8/1/2009 52 Male 306 lb 8/6/2010 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 5/26/2010 70 Male 154 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 219 lb 9/10/2010 Physician United States
Primary
Concomitant
Total Lung Capacity Decreased 1/1/2009 70 Male 202 lb 9/14/2010 Consumer United States
Primary
Concomitant
Nausea 5/26/2009 70 Female 270 lb 10/26/2010 Physician United States
Primary
Concomitant
Nausea Other Serious 1/1/2010 Female 11/3/2010 Other Health Professional United States
Primary
Concomitant
Application Site Rash 7/1/2010 80 Female 156 lb 11/23/2010 Consumer United States
Primary
Concomitant
Hypertension Other Serious 61 Female 238 lb 12/23/2010 Consumer Brazil
Primary
Concomitant
Ischaemic Cardiomyopathy Other Serious 7/8/2009 67 Male 1/17/2011 Consumer Italy
Primary
Concomitant
Death Death 2/5/2011 77 Female 227 lb 2/11/2011 Consumer United States
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 1/6/2011 76 Male 2/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data