Lasix combined with Loxonin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 10/27/2005 74 Female 1/6/2006 Other Health Professional France
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 5/27/2005 48 Female 12/30/2005 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 10/29/2004 46 Female 1/18/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/10/2005 67 Male 143 lb 2/1/2006 Physician Japan
Primary
Secondary
Tuberculous Pleurisy Hospitalization 8/23/2005 Female 2/6/2006 Physician Japan
Primary
Concomitant
Cellulitis Staphylococcal Hospitalization 6/25/2005 Female 2/10/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 4/21/2005 Female 137 lb 2/13/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/10/2005 67 Male 143 lb 2/24/2006 Physician Japan
Primary
Secondary
Vomiting Other Serious 10/27/2005 74 Female 3/15/2006 Other Health Professional France
Primary
Concomitant
Bronchitis Acute Hospitalization 12/30/2005 Female 137 lb 3/15/2006 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 2/4/2006 69 Female 117 lb 3/16/2006 Physician Japan
Primary
Secondary
Concomitant
Retinal Haemorrhage Life Threatening 2/4/2006 Female 3/21/2006 Physician Japan
Primary
Concomitant
Wheezing Death 3/1/2006 86 Female 3/28/2006 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 3/1/2006 86 Female 3/29/2006 Physician Japan
Primary
Secondary
Concomitant
Tuberculous Pleurisy Hospitalization 6/22/2005 Female 4/3/2006 Physician Japan
Primary
Concomitant
Visual Disturbance Disability 5/23/2005 78 Female 4/3/2006 Physician Japan
Primary
Concomitant
Wheezing Death 3/1/2006 86 Female 4/4/2006 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 3/1/2006 86 Female 4/7/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Inflammation Death 4/15/2005 83 Male 3/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Bronchitis Acute Hospitalization 12/30/2005 Female 137 lb 4/11/2006 Physician Japan
Primary
Secondary
Concomitant
Urticaria Other Serious 11/27/2003 Female 95 lb 4/20/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 4/23/2006 73 Female 128 lb 5/22/2006 Physician Japan
Primary
Concomitant
Osteoporosis Disability 11/1/2003 68 Male 5/25/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/23/2006 73 Female 128 lb 6/9/2006 Physician Japan
Primary
Concomitant
Bronchitis Acute Hospitalization 12/30/2005 Female 137 lb 6/28/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/16/2004 53 Male 122 lb 6/28/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/23/2006 73 Female 128 lb 7/12/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 4/23/2006 73 Female 128 lb 7/13/2006 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 6/9/2006 68 Male 7/17/2006 Physician France
Primary
Concomitant
Tuberculous Pleurisy Hospitalization 6/22/2005 Female 163 lb 7/24/2006 Physician Japan
Primary
Concomitant
Haemodialysis Hospitalization 7/9/2006 72 Female 7/24/2006 Physician Japan
Primary
Concomitant
Liver Abscess Hospitalization 6/24/2004 35 Male 121 lb 7/31/2006 Physician Japan
Primary
Concomitant
Hallucination Hospitalization 7/9/2006 72 Female 8/4/2006 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 7/12/2006 78 Female 157 lb 8/8/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 7/14/2006 Male 8/10/2006 Pharmacist Japan
Primary
Concomitant
Hallucination Hospitalization 7/9/2006 72 Female 8/11/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Disability 7/1/2003 52 Male 8/18/2006 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 7/12/2006 78 Female 157 lb 8/23/2006 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 7/16/2006 73 Male 121 lb 9/8/2006 Physician Japan
Primary
Secondary
Concomitant
Blood Potassium Decreased Other Serious 94 Female 9/11/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 7/16/2006 73 Male 121 lb 9/14/2006 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 7/6/2006 82 Female 86 lb 10/9/2006 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 7/6/2006 82 Female 86 lb 10/18/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/6/2006 82 Female 86 lb 10/26/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased 5/29/2006 Male 10/31/2006 Pharmacist Japan
Primary
Concomitant
Tuberculous Pleurisy Hospitalization 6/22/2005 Female 163 lb 11/7/2006 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 8/2/2006 Male 150 lb 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 5/26/2003 52 Male 12/15/2006 Physician Japan
Primary
Secondary
Concomitant
Wheezing Death 11/17/2006 57 Male 143 lb 12/22/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 11/3/2006 57 Male 143 lb 1/2/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 12/29/2006 Male 88 lb 2/12/2007 Other Health Professional Japan
Primary
Concomitant
Sarcoidosis Hospitalization 1/9/2007 Female 95 lb 3/1/2007 Physician Japan
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/22/2007 86 Female 3/2/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 2/13/2007 65 Female 132 lb 3/3/2007 Pharmacist Japan
Primary
Concomitant
Sarcoidosis Hospitalization 1/9/2007 Female 95 lb 3/26/2007 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 56 Male 4/6/2007 Pharmacist Japan
Primary
Concomitant
Weight Increased Other Serious Female 4/12/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2002 68 Male 104 lb 5/7/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 6/3/2007 80 Male 6/18/2007 Physician Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/22/2007 86 Female 6/25/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 6/3/2007 80 Male 6/26/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/13/2007 68 Female 6/29/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/13/2007 68 Female 141 lb 7/13/2007 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 6/3/2007 80 Male 7/13/2007 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemic Coma Life Threatening 7/7/2007 78 Female 7/20/2007 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/13/2007 68 Female 141 lb 7/23/2007 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemic Coma Life Threatening 7/7/2007 78 Female 7/24/2007 Physician Japan
Primary
Concomitant
Hypoglycaemic Coma Life Threatening 7/7/2007 78 Female 115 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 78 Female 8/16/2007 Pharmacist Japan
Primary
Concomitant
Anaphylactic Shock Other Serious 7/19/2007 Female 154 lb 8/17/2007 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 2/7/2005 73 Male 9/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 8/1/1996 47 Male 9/10/2007 Physician Japan
Primary
Secondary
Concomitant
Serratia Infection Other Serious 11/26/2003 Female 157 lb 10/16/2007 Physician Japan
Primary
Concomitant
Leukoencephalopathy Life Threatening 10/16/2007 Female 11/2/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Other Serious 9/17/2007 Male 145 lb 11/20/2007 Physician Japan
Primary
Concomitant
Renal Failure Life Threatening 10/16/2007 Female 11/28/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 3/1/2006 86 Female 12/19/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/29/2007 75 Male 12/20/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Other Serious 9/17/2007 Male 145 lb 12/20/2007 Physician Japan
Primary
Concomitant
Large Intestine Perforation Death 10/23/2007 Female 12/27/2007 Physician Japan
Primary
Concomitant
Nephritis Interstitial Disability 3/19/2007 66 Male 119 lb 1/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Postoperative Abscess Hospitalization 8/9/2007 Female 2/19/2008 Physician Japan
Primary
Concomitant
Swelling Face Other Serious 2/15/2008 Female 97 lb 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Swelling Face Other Serious 2/15/2008 Female 97 lb 3/27/2008 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 6/14/2005 37 Female 4/2/2008 Consumer Japan
Primary
Secondary
Concomitant
Large Intestine Perforation Death 8/9/2007 Female 4/7/2008 Physician Japan
Primary
Concomitant
Superinfection Other Serious 1/30/2007 75 Male 4/8/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/24/2005 39 Female 106 lb 4/15/2008 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 6/14/2005 37 Female 4/29/2008 Consumer Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/9/2004 36 Male 5/3/2008 Consumer United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 8/9/2007 Female 5/22/2008 Physician Japan
Primary
Secondary
Hepatic Function Abnormal Hospitalization 4/25/2008 Female 85 lb 5/30/2008 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 4/25/2008 Female 85 lb 6/9/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 6/3/2008 77 Male 146 lb 6/20/2008 Physician Japan
Primary
Concomitant
Cardiac Failure Other Serious 5/23/2008 44 Male 6/20/2008 Other Health Professional Japan
Primary
Concomitant
Jaundice Other Serious 5/14/2008 Male 144 lb 6/30/2008 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 5/14/2008 68 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 5/14/2008 68 Male 7/10/2008 Physician Japan
Primary
Secondary
Concomitant
Jaundice Other Serious 5/14/2008 Male 144 lb 7/15/2008 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 5/23/2008 Male 121 lb 7/18/2008 Other Health Professional Japan
Primary
Concomitant
Rash Death 4/25/2008 78 Male 121 lb 8/18/2008 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 3/31/2008 Male 164 lb 9/5/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 3/17/2008 Male 95 lb 9/23/2008 Physician Japan
Primary
Concomitant
Pneumonia Aspiration Life Threatening 3/17/2008 Male 95 lb 10/3/2008 Physician Japan
Primary
Concomitant
Respiratory Disorder Life Threatening 9/4/2008 Female 101 lb 10/10/2008 Physician Japan
Primary
Concomitant
Stasis Dermatitis 8/2/2008 Male 123 lb 10/15/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 3/17/2008 Male 95 lb 10/27/2008 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 6/30/2007 82 Female 88 lb 10/29/2008 Other Health Professional Japan
Primary
Concomitant
Hepatic Encephalopathy Death 77 Male 11/7/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2008 Male 162 lb 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 8/26/2008 Male 11/17/2008 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Death 4/4/2008 Male 11/21/2008 Physician Japan
Primary
Concomitant
Hepatitis Fulminant Death 9/1/2008 Male 11/21/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 10/16/2008 59 Male 106 lb 12/5/2008 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2008 Male 162 lb 12/16/2008 Physician Japan
Primary
Secondary
Concomitant
Syncope Other Serious 10/14/2008 61 Male 12/17/2008 Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 8/26/2008 Male 1/14/2009 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 6/30/2007 82 Female 88 lb 1/23/2009 Other Health Professional Japan
Primary
Concomitant
Leukoencephalopathy Other Serious 4/3/2008 Male 2/12/2009 Consumer Japan
Primary
Concomitant
Syncope Other Serious 10/14/2008 61 Male 12/17/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/30/2008 Male 132 lb 2/25/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/2/2008 56 Female 117 lb 2/26/2009 Physician Japan
Primary
Concomitant
Pyothorax Hospitalization 6/27/2007 82 Female 88 lb 2/27/2009 Other Health Professional Japan
Primary
Concomitant
Pneumonia Aspiration Death 12/18/2008 Male 3/2/2009 Physician Japan
Primary
Concomitant
Anaemia Hospitalization 1/16/2009 3/11/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Hypercalcaemia Life Threatening 2/18/2009 Female 84 lb 3/13/2009 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 1/3/2009 3/13/2009 Physician Japan
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 3/1/2009 65 Male 141 lb 3/20/2009 Physician Japan
Primary
Concomitant
Shock Death 9/20/2008 Male 3/23/2009 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 1/3/2009 3/24/2009 Physician Japan
Primary
Secondary
Concomitant
Concomitant Disease Aggravated Other Serious 2/18/2009 Female 84 lb 3/26/2009 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 1/3/2009 3/30/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/24/2008 4/1/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Death 3/5/2009 Male 137 lb 4/3/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 5/23/2008 Male 121 lb 4/3/2009 Other Health Professional France
Primary
Concomitant
Renal Impairment Hospitalization 4/2/2008 56 Female 117 lb 4/9/2009 Physician Japan
Primary
Concomitant
Osteomyelitis Other Serious 9/7/2008 71 Male 4/15/2009 Physician Japan
Primary
Concomitant
Delirium Other Serious 77 Male 5/14/2009 Pharmacist Japan
Primary
Concomitant
Renal Cell Carcinoma Life Threatening 3/1/2009 65 Male 141 lb 5/20/2009 Physician Japan
Primary
Concomitant
Death Death 4/13/2009 60 5/21/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/31/2009 77 Female 5/26/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 4/2/2008 56 Female 117 lb 5/27/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Death 3/5/2009 Male 137 lb 5/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Prostate Cancer Recurrent Other Serious 9/7/2008 Male 6/5/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 6/1/2007 54 Female 6/8/2009 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/1/2007 55 Female 6/12/2009 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 10/16/2008 59 Male 106 lb 6/16/2009 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/24/2008 62 6/16/2009 Physician Japan
Primary
Concomitant
Malaise Hospitalization 10/16/2008 59 Male 106 lb 6/17/2009 Physician Germany
Primary
Secondary
Concomitant
Death Death 48 6/24/2009 Physician Japan
Primary
Concomitant

Drug Data