Lasix combined with Leucovorin Calcium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 9/19/2005 81 Female 1/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Perforation Hospitalization 7/5/2005 68 Female 245 lb 6/5/2006 Physician Canada
Primary
Secondary
Concomitant
Weight Decreased 2/9/2006 Male 4/17/2006 Consumer United States
Primary
Concomitant
Coma Other Serious 5/1/2005 75 Male 7/19/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 7/18/2006 78 Female 8/25/2006 Pharmacist United States
Primary
Concomitant
Disease Progression Death 12/7/2004 Male 116 lb 7/24/2006 Physician United States
Primary
Concomitant
Fatigue Hospitalization 10/5/2006 Male 206 lb 10/11/2006 Consumer United States
Primary
Secondary
Concomitant
Urticaria Other Serious 9/1/2006 Female 10/18/2006 Consumer United States
Primary
Concomitant
Skin Infection Hospitalization 5/1/2005 Female 305 lb 10/19/2006 Physician United States
Primary
Concomitant
Performance Status Decreased Hospitalization 10/5/2006 74 Male 10/23/2006 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 10/28/2006 Male 11/8/2006 Physician Canada
Primary
Concomitant
Malnutrition Hospitalization 10/10/2006 Female 11/8/2006 Physician United States
Primary
Secondary
Concomitant
Pitting Oedema Hospitalization 10/22/2006 74 Male 206 lb 11/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/2/2006 Male 150 lb 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Hypotension Hospitalization 11/11/2006 Female 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Urine Bilirubin Increased Hospitalization 10/22/2006 74 Male 206 lb 11/28/2006 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/2/2006 Female 51 lb 11/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 10/22/2006 Male 206 lb 12/11/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/21/2006 Male 112 lb 12/12/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Death 5/4/2005 Female 155 lb 12/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 50 Female 1/4/2007 Pharmacist Canada
Primary
Concomitant
Respiratory Arrest Death 12/26/2006 75 Male 2/8/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 1/19/2007 73 Male 2/16/2007 Other Health Professional United States
Primary
Concomitant
Hypomagnesaemia 9/12/2006 68 Male 258 lb 2/28/2007 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/9/2007 Female 273 lb 3/12/2007 United States
Primary
Secondary
Concomitant
Pre-existing Condition Improved 1/1/2007 50 Female 201 lb 3/27/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2005 48 Male 4/2/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 10/28/2006 Male 4/20/2007 Physician Canada
Primary
Concomitant
Drug Interaction Other Serious 2/22/2007 14 Male 62 lb 4/12/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Interaction Other Serious 2/22/2007 14 Male 62 lb 5/2/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 10/28/2006 Male 5/14/2007 Physician Canada
Primary
Concomitant
Renal Failure Acute Other Serious 7/18/2006 Female 5/17/2007 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/9/2007 Female 7/6/2007 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 1/25/2005 41 Female 244 lb 7/16/2007 United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 6/4/2007 Male 7/24/2007 Physician United States
Primary
Secondary
Concomitant
Hyperammonaemia Life Threatening 10/5/2006 Female 154 lb 7/25/2007 Physician Japan
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 47 Female 9/10/2007 Other Health Professional Canada
Primary
Concomitant
Systemic Candida Life Threatening 8/1/2005 62 Male 130 lb 10/15/2007 Physician Japan
Primary
Secondary
Concomitant
Wound Treatment Hospitalization 1/25/2005 41 Female 220 lb 11/14/2007 United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 10/28/2007 Female 11/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 1/23/2006 Female 203 lb 11/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 2/22/2007 14 Male 62 lb 11/29/2007 Physician Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/6/2007 Male 1/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 2/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 2/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Petechiae Other Serious 7/23/2007 Female 179 lb 3/10/2008 Physician Germany
Primary
Concomitant
Generalised Erythema Other Serious 11/14/2007 Female 132 lb 3/10/2008 Physician Germany
Primary
Concomitant
Shock Haemorrhagic Life Threatening 3/28/2008 Male 134 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 10/29/2007 Male 4/28/2008 Pharmacist United States
Primary
Concomitant
Dehydration Hospitalization 6/22/2008 Male 141 lb 7/7/2008 United States
Primary
Secondary
Concomitant
Tunnel Vision Other Serious 1/1/2006 75 Male 7/10/2008 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 7/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Hospitalization 3/28/2008 Male 134 lb 7/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 5/25/2008 Male 151 lb 7/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 3/31/2008 Male 134 lb 7/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 5/25/2008 Male 151 lb 7/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 10/30/1999 Male 175 lb 8/4/2008 Physician United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 3/28/2008 Male 134 lb 8/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/29/2008 Female 114 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 8/15/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 8/15/2008 Other Health Professional Brazil
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 10/29/2007 Female 124 lb 8/20/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2005 61 Female 199 lb 8/21/2008 United States
Primary
Concomitant
Anaphylactic Shock Hospitalization 7/9/2008 Male 138 lb 8/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 6/22/2008 Male 141 lb 8/29/2008 United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 5/25/2008 Male 151 lb 9/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Anaphylactic Shock Hospitalization 7/9/2008 Male 138 lb 9/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 9/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Colitis Hospitalization 8/31/2008 Male 170 lb 10/1/2008 Physician United States
Primary
Concomitant
Colitis Hospitalization 8/31/2008 Male 170 lb 10/8/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 5/29/2008 Female 114 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 12/9/2007 Female 88 lb 10/17/2008 Consumer Japan
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 10/16/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 10/16/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 8/27/2008 68 Female 141 lb 10/21/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 4/18/2008 Male 57 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Other Serious 5/21/2008 Male 194 lb 11/4/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Drug Eruption Hospitalization 6/16/2008 Female 11/4/2008 Consumer Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 166 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 Female 138 lb 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 3/28/2008 Male 134 lb 12/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 11/18/2008 53 Male 12/17/2008 Other Health Professional United States
Primary
Concomitant
Shock Haemorrhagic Other Serious 3/31/2008 Male 134 lb 12/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 9/26/2008 61 Female 111 lb 1/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 10 Male 2/10/2009
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 3/31/2008 Male 134 lb 3/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 12/28/2007 Male 165 lb 5/4/2009 Physician Japan
Primary
Secondary
Concomitant
Scrotal Oedema Hospitalization 5/26/2008 68 Male 5/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 10/10/2008 56 Male 121 lb 5/20/2009 Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 10/10/2008 56 Male 121 lb 5/21/2009 Japan
Primary
Secondary
Concomitant
Stomatitis Life Threatening 3/16/2009 75 Male 5/21/2009 Physician Germany
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 3/28/2008 78 Male 150 lb 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/7/2008 69 Female 109 lb 7/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 3/28/2008 78 Male 150 lb 8/11/2009 Physician United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 3/28/2008 78 Male 150 lb 8/17/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 10/3/2008 56 Male 121 lb 9/15/2009 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/7/2009 Female 126 lb 10/15/2009 United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Hospitalization 10/20/2009 Female 126 lb 11/11/2009 United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 7/22/2009 Male 224 lb 12/3/2009 Consumer United States
Primary
Concomitant
Shock Haemorrhagic Hospitalization 3/28/2008 78 Male 134 lb 1/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/7/2008 69 Female 109 lb 1/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 3/28/2008 Male 134 lb 1/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 3/28/2008 79 Male 134 lb 2/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/28/2008 Male 134 lb 2/2/2010 Other Health Professional France
Primary
Secondary
Concomitant
Wound Infection Other Serious 7/22/2009 Male 224 lb 2/5/2010 Consumer United States
Primary
Concomitant
Shock Haemorrhagic Hospitalization 3/28/2008 78 Male 134 lb 2/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Hospitalization 3/28/2008 78 Male 134 lb 2/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Hospitalization 3/28/2008 78 Male 134 lb 2/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 3/28/2008 Male 134 lb 2/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetic Foot Hospitalization 1/5/2010 Female 148 lb 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Stomatitis Life Threatening 3/16/2009 75 Male 161 lb 4/28/2010 Physician Germany
Primary
Secondary
Concomitant
Shock Haemorrhagic Hospitalization 3/28/2008 78 Male 134 lb 4/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Death 1/18/2008 70 Female 185 lb 5/7/2010 Lawyer United States
Primary
Concomitant
Respiratory Failure Life Threatening 4/12/2010 66 Female 264 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization Female 275 lb 6/8/2010 Consumer United States
Primary
Concomitant
Small Intestinal Perforation Other Serious 11/1/2008 60 Male 119 lb 6/8/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 4/12/2010 66 Female 264 lb 7/16/2010 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 51 Female 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 4/12/2010 66 Female 264 lb 8/12/2010 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/6/2010 69 Male 172 lb 8/13/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 4/12/2010 66 Female 264 lb 9/1/2010 Physician United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 9/8/2010 69 Male 160 lb 10/8/2010 Physician United States
Primary
Secondary
Concomitant
Pyothorax Other Serious 6/18/2010 74 Female 121 lb 10/28/2010 Physician Japan
Primary
Concomitant
Respiratory Syncytial Virus Test Positive Life Threatening 11/16/2010 14 Female 130 lb 11/24/2010 Physician United States
Primary
Secondary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/16/2010 14 Female 130 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Carotid Arteriosclerosis Hospitalization 12/30/2010 72 Male 5/6/2011 Other Health Professional France
Primary
Secondary
Concomitant
Diarrhoea Life Threatening 12/30/2010 72 Male 5/10/2011 Other Health Professional France
Primary
Secondary
Concomitant
Pruritus Hospitalization 10/11/2010 78 Male 130 lb 5/17/2011 Physician Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 3/24/2011 74 Male 139 lb 5/19/2011 Consumer Germany
Primary
Concomitant
Psychomotor Hyperactivity Hospitalization 3/22/2011 79 Male 5/17/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 12/30/2010 72 Male 5/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 11/24/2010 62 Female 95 lb 6/1/2011 Physician Japan
Primary
Concomitant
Pain Other Serious 8/18/2010 66 Male 159 lb 6/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 6/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Eczema Death 12/1/2010 60 Male 148 lb 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/30/2010 75 Female 117 lb 6/13/2011 Other Health Professional Japan
Primary
Concomitant
Colorectal Cancer Other Serious 8/18/2010 66 Male 159 lb 7/1/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Death 1/21/2011 73 Female 137 lb 7/1/2011 Physician Japan
Primary
Secondary
Concomitant
Paronychia Other Serious 9/13/2010 67 Female 95 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Death 12/1/2010 60 Male 148 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 11/24/2010 62 Female 95 lb 7/18/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Death 6/19/2011 71 Male 123 lb 7/22/2011 Other Health Professional Japan
Primary
Concomitant

Drug Data