Lantus combined with Sodium Bicarbonate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 5/11/2005 60 Male 3/24/2006 United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 5/25/2006 Male 164 lb 7/28/2006 Physician United States
Primary
Concomitant
Anaemia 9/2/2005 Female 213 lb 8/9/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Death 6/8/2006 53 Male 8/9/2006 Physician United States
Primary
Secondary
Concomitant
Blood Erythropoietin Increased Hospitalization 5/25/2006 Male 164 lb 9/6/2006 Physician United States
Primary
Concomitant
Pitting Oedema Other Serious 37 Female 229 lb 5/8/2007 Physician United States
Primary
Concomitant
Medication Error 1/1/2006 69 Male 230 lb 1/25/2007 United States
Primary
Secondary
Concomitant
Medication Error 1/1/2006 69 Male 230 lb 4/23/2007 United States
Primary
Secondary
Concomitant
Pitting Oedema Other Serious 37 Female 229 lb 6/20/2007 Physician United States
Primary
Concomitant
Ileus Paralytic Hospitalization 1/23/2005 Female 6/28/2007 Physician United States
Primary
Secondary
Concomitant
Anaemia Other Serious 1/16/2007 Male 7/2/2007 Physician Germany
Primary
Concomitant
Anaemia Other Serious 1/16/2007 Male 7/16/2007 Physician Germany
Primary
Concomitant
Anaemia Other Serious 1/16/2007 Male 8/1/2007 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/17/2007 60 Male 208 lb 8/21/2007 United States
Primary
Secondary
Concomitant
Anaemia Other Serious 1/16/2007 Male 9/7/2007 Physician Germany
Primary
Secondary
Concomitant
Metabolic Encephalopathy Other Serious 2/20/2005 Male 162 lb 10/29/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/1/2007 Female 11/27/2007 Physician United States
Primary
Concomitant
Rash Erythematous Hospitalization 64 Male 178 lb 1/10/2008 Physician United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 1/23/2005 Female 1/25/2008 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 1/10/2008 Male 179 lb 2/15/2008 Netherlands
Primary
Concomitant
Feeling Abnormal 1/3/2008 Female 2/17/2008 United States
Primary
Concomitant
Rash Erythematous Hospitalization 12/24/2007 64 Male 2/24/2008 United States
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 64 Male 178 lb 2/26/2008 Other Health Professional United States
Primary
Concomitant
Feeling Abnormal 1/3/2008 Female 2/27/2008 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 12/28/2007 59 Male 3/3/2008 Other Health Professional United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 1/10/2008 Male 179 lb 4/24/2008 Netherlands
Primary
Concomitant
Hypoglycaemia Other Serious 2/15/2007 59 Female 174 lb 4/30/2008 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 41 8/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Renal Failure Hospitalization 3/1/2008 Female 9/3/2008 Other Health Professional France
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 4/24/2007 10/1/2008 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Renal Cancer Other Serious Male 12/4/2008 Consumer United States
Primary
Secondary
Concomitant
Anaemia Other Serious Male 12/31/2008 Physician United States
Primary
Concomitant
Renal Cancer Other Serious Male 1/20/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Male 1/26/2009 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 2/2/2009 Pharmacist United States
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 6/1/2007 Male 219 lb 2/4/2009 Physician United States
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 6/1/2007 Male 219 lb 2/11/2009 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 4/24/2007 2/19/2009 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 4/24/2007 2/19/2009 Physician United States
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 6/1/2007 Male 219 lb 3/4/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/10/2005 66 Female 199 lb 4/20/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/12/2009 58 Male 225 lb 4/27/2009 Other Health Professional United States
Primary
Concomitant
Rash Pruritic 3/27/2009 Male 6/30/2009 United States
Primary
Concomitant
Off Label Use Other Serious 2/5/2004 7/7/2009 Physician United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 2/5/2004 7/30/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2009 Male 8/24/2009 Physician United States
Primary
Concomitant
Dementia Hospitalization 9/1/2009 68 Male 12/23/2009 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/13/2009 62 Male 12/24/2009 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 10/1/2007 63 Female 1/11/2010 Lawyer United States
Primary
Concomitant
Tremor Disability 8/1/2008 43 Female 165 lb 2/10/2010 Physician Germany
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 9/1/2007 61 Male 3/17/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 69 Male 3/5/2010 Lawyer United States
Primary
Concomitant
Zinc Deficiency Other Serious 2/5/2004 3/18/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2009 63 Male 3/30/2010 Consumer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 10/22/2007 63 Female 4/7/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/23/2006 56 Female 5/12/2010 Physician United States
Primary
Concomitant
Coronary Artery Disease Other Serious 50 Male 309 lb 5/20/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/23/2006 56 Female 6/2/2010 Physician United States
Primary
Concomitant
Status Epilepticus Other Serious 9/1/2007 61 Male 165 lb 6/17/2010 Lawyer United States
Primary
Concomitant
Metastatic Bronchial Carcinoma Hospitalization 9/28/2009 67 Male 6/29/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/3/2010 65 Female 7/6/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2008 45 Male 170 lb 8/4/2010 Lawyer United States
Primary
Concomitant
Status Epilepticus Other Serious 9/1/2007 61 Male 165 lb 9/22/2010 Lawyer United States
Primary
Concomitant
Renal Failure Acute Other Serious 5/3/2010 65 Female 9/30/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 45 Male 170 lb 9/30/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 42 Female 183 lb 10/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 42 Female 183 lb 10/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 9/2/2010 45 Female 132 lb 11/18/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 2/20/2007 69 Female 139 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Hospitalization 10/3/2010 90 Female 12/3/2010 Physician Italy
Primary
Concomitant
Creatinine Urine Increased Hospitalization 1/1/2010 80 Female 128 lb 12/15/2010 Consumer Brazil
Primary
Concomitant
Sepsis Life Threatening 12/18/2010 55 Female 164 lb 12/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 10/3/2010 90 Female 12/30/2010 Physician Italy
Primary
Concomitant
Angiogram Other Serious 5/1/2010 1/13/2011 Other Health Professional United States
Primary
Concomitant
Chest Pain Hospitalization 7/7/2010 70 Female 1/26/2011 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Death 5/18/2010 2/11/2011 Consumer United States
Primary
Concomitant
Chest Pain Other Serious 7/7/2010 70 Female 2/14/2011 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Death 5/18/2010 2/15/2011 Physician United States
Primary
Concomitant
Portal Vein Thrombosis Hospitalization 7/7/2010 70 Female 2/22/2011 Physician United States
Primary
Concomitant
Splenomegaly Other Serious 7/7/2010 70 Female 3/4/2011 Physician United States
Primary
Concomitant
Pneumonia Other Serious Female 3/15/2011 Consumer United States
Primary
Concomitant
Postrenal Failure Hospitalization 3/1/2011 68 Male 163 lb 3/18/2011 Physician France
Primary
Secondary
Concomitant
Sudden Death Other Serious 3/1/2011 68 Male 3/23/2011 Physician France
Primary
Secondary
Concomitant
Pain Hospitalization 8/5/2006 69 Male 205 lb 3/23/2011 Lawyer United States
Primary
Concomitant
Postrenal Failure Death 3/1/2011 68 Male 163 lb 3/24/2011 Physician France
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 12/7/2010 68 Female 3/25/2011 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2011 68 Male 3/29/2011 Physician France
Primary
Concomitant
Spontaneous Haematoma Hospitalization 12/7/2010 68 Female 4/1/2011 Consumer France
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 1/27/2011 69 Female 130 lb 4/4/2011 Physician France
Primary
Secondary
Concomitant
Emotional Distress Hospitalization 3/1/2006 48 Male 220 lb 4/6/2011 Other Health Professional United States
Primary
Concomitant
Confusional State Other Serious 11/1/2007 58 Male 137 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization Female 4/18/2011 Physician United States
Primary
Concomitant
Fear Other Serious 66 Female 4/19/2011 Other Health Professional United States
Primary
Concomitant
Walking Disability Other Serious 3/1/2007 55 Female 190 lb 5/4/2011 Other Health Professional United States
Primary
Concomitant
Sudden Death Hospitalization 3/1/2011 68 Male 163 lb 5/10/2011 Physician France
Primary
Secondary
Concomitant
Pancreatitis Hospitalization Female 199 lb 5/17/2011 Consumer United States
Primary
Concomitant
Death Other Serious 3/19/2003 67 Male 192 lb 5/18/2011 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/31/2011 90 Male 144 lb 5/20/2011 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 1/1/1997 61 Female 5/24/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 5/29/2003 68 Male 229 lb 5/26/2011 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 11/29/2003 63 Female 269 lb 5/28/2011 Other Health Professional United States
Primary
Concomitant
Death Hospitalization 10/1/2006 70 Male 295 lb 5/28/2011 Consumer United States
Primary
Concomitant
Fear Other Serious 3/25/2006 64 Female 220 lb 6/2/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 4/26/2003 67 Male 201 lb 6/1/2011 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization Female 5/26/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 12/11/2009 56 Male 236 lb 6/3/2011 Physician United States
Primary
Secondary
Concomitant
Uterine Cancer Other Serious Female 249 lb 6/8/2011 Pharmacist United States
Primary
Concomitant
Pain Other Serious 10/15/2005 70 Female 174 lb 6/13/2011 Consumer United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2006 49 Male 170 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Anaemia Other Serious 4/29/2011 69 Male 133 lb 6/24/2011 Physician United States
Primary
Concomitant
Anxiety Other Serious 5/29/2003 68 Male 229 lb 6/23/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/12/2011 72 Male 7/5/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/12/2011 72 Male 7/5/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Fear Other Serious 1/5/2004 59 Male 174 lb 7/11/2011 Consumer United States
Primary
Concomitant
Injury Hospitalization 8/5/2006 70 Male 205 lb 7/13/2011 Other Health Professional United States
Primary
Concomitant
Pain Death 1/5/2004 59 Male 174 lb 7/14/2011 Consumer United States
Primary
Concomitant
Renal Failure Chronic Other Serious 6/4/2004 48 Female 119 lb 7/14/2011 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/12/2011 72 Male 7/20/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/12/2011 72 Male 7/22/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Off Label Use Other Serious 2/15/1995 34 Female 130 lb 7/22/2011 Consumer United States
Primary
Concomitant
Swelling Other Serious Female 8/8/2011 Consumer United States
Primary
Concomitant
Emotional Distress Death 5/29/2003 68 Male 229 lb 8/22/2011 Lawyer United States
Primary
Concomitant
Atherectomy Death 5/1/2010 81 Male 9/6/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 5/1/2010 81 Male 9/9/2011 Other Health Professional United States
Primary
Concomitant
Death Other Serious 5/1/2010 81 Male 9/13/2011 Physician United States
Primary
Concomitant
Neutropenia Other Serious 11/24/2010 63 Male 9/15/2011 Physician Japan
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 4/1/2010 57 Male 144 lb 9/29/2011 Lawyer United States
Primary
Concomitant
Anaemia Other Serious 11/1/2007 58 Male 137 lb 10/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Splenomegaly Other Serious 7/7/2010 70 Female 10/19/2011 Physician United States
Primary
Concomitant
Hyperkalaemia Hospitalization 9/17/2011 42 Male 191 lb 10/19/2011 Physician United States
Primary
Secondary
Concomitant
Bronchitis Hospitalization 9/17/2011 42 Male 191 lb 11/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bronchitis Hospitalization 9/17/2011 42 Male 191 lb 11/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypercholesterolaemia Hospitalization 5/1/2008 41 Female 225 lb 11/9/2011 Physician United States
Primary
Concomitant
In-stent Coronary Artery Restenosis Other Serious 66 Female 12/8/2011 Other Health Professional United States
Primary
Concomitant
Pancreatic Disorder Hospitalization 1/1/1995 57 Male 12/9/2011 Consumer United States
Primary
Secondary
Concomitant
Brain Injury Hospitalization 4/28/2011 70 Female 159 lb 12/13/2011 Physician United States
Primary
Secondary
Concomitant
Coronary Arterial Stent Insertion Hospitalization 1/1/1995 57 Male 12/13/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/9/2011 59 Female 162 lb 12/19/2011 Physician United States
Primary
Concomitant
Renal Failure Death 11/19/2011 80 Male 182 lb 1/6/2012 Physician United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 1/14/2012 66 Female 146 lb 2/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/9/2011 59 Female 162 lb 2/8/2012 Physician United States
Primary
Concomitant
Pancytopenia Hospitalization 1/14/2012 66 Female 146 lb 2/14/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Female 3/5/2012 Physician United States
Primary
Concomitant
Pneumonia Life Threatening 1/14/2012 66 Female 146 lb 3/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data