Lantus combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Foot Fracture Required Intervention 12/1/2005 62 Female 1/26/2006 Consumer United States
Primary
Concomitant
Ventricular Dysfunction Life Threatening 8/30/2005 Male 139 lb 2/8/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 1/18/2006 Female 245 lb 2/9/2006 Consumer United States
Primary
Secondary
Concomitant
Skin Exfoliation Disability 8/24/2004 72 Female 188 lb 2/13/2006 Physician Brazil
Primary
Secondary
Concomitant
Pneumonia Death 12/25/2005 57 Male 235 lb 2/14/2006 Other Health Professional United States
Primary
Concomitant
Psychotic Disorder Hospitalization 6/1/2005 59 Male 262 lb 2/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 11/23/2003 61 Male 256 lb 3/1/2006 Lawyer United States
Primary
Concomitant
Rotator Cuff Syndrome Hospitalization 11/27/2003 61 Male 256 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Psychotic Disorder Hospitalization 1/19/2006 59 Male 262 lb 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 2/2/2006 70 Male 3/3/2006 United Kingdom
Primary
Concomitant
Sinus Bradycardia Hospitalization 11/27/2003 61 Male 256 lb 3/17/2006 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 3/6/2006 72 Male 3/22/2006 Korea, Republic Of
Primary
Concomitant
Sinus Bradycardia Other Serious 11/27/2003 61 Male 256 lb 3/30/2006 Physician United States
Primary
Concomitant
Stupor Hospitalization 3/5/2006 72 Male 4/18/2006 Korea, Republic Of
Primary
Concomitant
Delusion Other Serious 11/22/2005 53 Male 210 lb 5/1/2006 Physician United States
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 4/17/2006 76 Female 7/12/2006 Other Health Professional France
Primary
Secondary
Concomitant
Stupor Hospitalization 3/5/2006 72 Male 7/18/2006 Korea, Republic Of
Primary
Concomitant
Hyperglycaemia Hospitalization 49 Female 5/8/2006 United States
Primary
Concomitant
Hyperglycaemia Hospitalization 49 Female 5/8/2006 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/16/2005 66 Female 134 lb 5/8/2006 Physician United States
Primary
Concomitant
Hyperglycaemia Other Serious 12/14/2005 79 Male 170 lb 5/8/2006 Physician United States
Primary
Secondary
Concomitant
Rash Generalised 3/22/2005 53 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Hypotension 3/8/2006 66 Male 6/28/2006 United States
Primary
Concomitant
Neutropenia Hospitalization 4/17/2006 76 Female 8/23/2006 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 4/17/2006 76 Female 8/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/30/2007 60 Male 5/14/2007 Physician United States
Primary
Concomitant
Blood Glucose Increased 8/1/2006 36 Female 4/23/2007 United States
Primary
Secondary
Concomitant
Hypoglycaemia 2/2/2007 58 Female 5/17/2007 United States
Primary
Concomitant
Cardiac Arrest Death 1/31/2007 60 Female 6/11/2007 Physician Australia
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 10/1/2006 93 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 12/29/2006 54 Female 277 lb 4/26/2007 United States
Primary
Concomitant
Hypoglycaemia Other Serious 10/1/2006 40 Male 4/26/2007 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 53 Male 216 lb 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Nervousness Hospitalization 9/20/2006 80 Male 181 lb 4/26/2007 United States
Primary
Concomitant
Weight Increased Other Serious 9/1/2006 Female 4/26/2007 United States
Primary
Concomitant
Hyperglycaemia Other Serious 5/23/2006 52 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 5/9/2006 61 Male 4/26/2007 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 5/1/2006 77 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Tremor Other Serious 3/1/2007 64 Male 263 lb 4/26/2007 United States
Primary
Concomitant
Hypoglycaemia Other Serious 1/1/2006 Male 4/26/2007 United States
Primary
Secondary
Hyperglycaemia Other Serious 1/1/2006 51 Female 226 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 4/6/2006 59 Male 179 lb 4/26/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 12/16/2006 60 Male 300 lb 4/26/2007 United States
Primary
Concomitant
Hypoglycaemia Other Serious 12/4/2006 58 Male 201 lb 4/26/2007 Physician United States
Primary
Concomitant
Hyperglycaemia Other Serious 11/28/2006 61 Female 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Injection Site Bruising Other Serious 60 Male 4/26/2007 United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 1/15/2006 61 Male 4/26/2007 United States
Primary
Secondary
Concomitant
Overdose Other Serious 3/6/2007 83 Male 4/26/2007 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 45 Female 188 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 12/28/2006 75 Female 218 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 12/14/2005 79 Male 170 lb 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 11/28/2005 59 Male 185 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 1/6/2007 51 Female 191 lb 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Throat Irritation 6/5/2007 71 Male 8/16/2007 United States
Primary
Concomitant
Eye Pruritus 3/1/2007 46 Male 7/26/2007 United States
Primary
Concomitant
Anaphylactic Reaction Other Serious 10/18/2007 Female 166 lb 11/19/2007 Physician United States
Primary
Concomitant
Overdose Other Serious 1/1/2007 Female 140 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 10/19/2007 Male 11/16/2007 Physician Germany
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 56 Male 11/16/2007 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 5/19/2006 73 Male 280 lb 11/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Incorrect Dose Administered 1/1/2007 56 Female 1/10/2008 Consumer United States
Primary
Concomitant
Protein Urine Present Other Serious 6/1/2006 56 Male 3/17/2008
Primary
Secondary
Concomitant
Proteinuria Other Serious 6/1/2006 56 Male 3/20/2008 Physician Canada
Primary
Secondary
Concomitant
Weight Increased Other Serious 56 Female 207 lb 4/4/2008 Consumer Turkey
Primary
Secondary
Concomitant
Nephritis Interstitial Other Serious 6/1/2006 56 Male 4/14/2008 Physician United States
Primary
Secondary
Concomitant
Intra-abdominal Haematoma Hospitalization 4/28/2008 77 Male 231 lb 6/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Other Serious 7/1/2007 69 Male 205 lb 4/30/2008 United States
Primary
Concomitant
Hypoglycaemia Other Serious 2/1/2008 51 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 64 Male 181 lb 4/30/2008 United States
Primary
Concomitant
Incorrect Dose Administered Other Serious 9/1/2006 60 Female 242 lb 4/30/2008 United States
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 10/1/2006 93 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 5/1/2006 77 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/30/2007 60 Male 7/10/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 56 Female 207 lb 7/15/2008 Consumer Turkey
Primary
Secondary
Concomitant
Nephritis Allergic Other Serious 6/1/2006 56 Male 7/15/2008 Physician United States
Primary
Secondary
Concomitant
Drug Intolerance Other Serious 1/1/2002 Female 212 lb 8/7/2008 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea 1/1/2008 65 Female 250 lb 7/7/2008 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization Female 179 lb 8/22/2008 Belgium
Primary
Concomitant
Myeloid Maturation Arrest Life Threatening 4/7/2008 8/28/2008 Other Health Professional France
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 9/17/2008 58 Female 210 lb 10/13/2008 United States
Primary
Secondary
Concomitant
Paralysis Hospitalization 5/1/2006 41 Male 365 lb 10/20/2008 Consumer United States
Primary
Concomitant
Pancreatitis Necrotising Hospitalization 8/7/2008 Male 172 lb 10/14/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/21/2008 71 Male 156 lb 10/21/2008 Physician United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 9/11/2008 40 Female 10/21/2008 Consumer South Africa
Primary
Concomitant
Neuroendocrine Tumour Other Serious 3/14/2008 61 Male 154 lb 10/22/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 10/2/2008 Female 10/22/2008 Pharmacist United States
Primary
Concomitant
Unintended Pregnancy Other Serious 2/1/2009 Female 216 lb 3/25/2009 Other Health Professional United States
Primary
Concomitant
Unintended Pregnancy Other Serious 2/1/2009 Female 216 lb 4/10/2009 Other Health Professional United States
Primary
Concomitant
Unintended Pregnancy Other Serious Female 216 lb 4/30/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 40 Female 166 lb 5/14/2009 United States
Primary
Concomitant
Diabetes Mellitus 12/30/2004 31 Male 160 lb 5/21/2009 Other Health Professional United States
Primary
Concomitant
Peripheral Ischaemia 9/1/2008 78 Male 171 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Pyrexia 2/25/2009 57 Female 225 lb 5/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/5/2006 61 Male 6/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/27/2009 Female 6/2/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 49 Female 6/2/2009 Spain
Primary
Secondary
Concomitant
Palpitations Other Serious 1/30/2009 61 Female 93 lb 6/5/2009 Other Health Professional Thailand
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 1/1/2007 Female 220 lb 6/5/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 12/1/2007 54 Male 168 lb 6/5/2009 Consumer United States
Primary
Concomitant
Injection Site Reaction Hospitalization 7/17/2003 50 Male 163 lb 6/8/2009 Physician Japan
Primary
Secondary
Concomitant
Tremor Hospitalization 4/23/2009 Male 550 lb 6/8/2009 Other Health Professional United States
Primary
Concomitant
Musculoskeletal Chest Pain 10/16/2008 Female 6/11/2009 United States
Primary
Concomitant
Injection Site Pain 1/1/2008 Male 289 lb 6/11/2009 Consumer United States
Primary
Concomitant
Fatigue 2/19/2009 Male 280 lb 6/12/2009 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2009 Female 178 lb 6/12/2009 Consumer United States
Primary
Concomitant
Pain Female 304 lb 6/12/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/26/2009 69 Female 159 lb 6/12/2009 Consumer Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/21/2009 Female 136 lb 6/15/2009 Physician United States
Primary
Concomitant
Paralysis Hospitalization 5/1/2006 41 Male 365 lb 6/15/2009 Other Health Professional United States
Primary
Concomitant
Abdominal Hernia Hospitalization 11/1/2008 Female 6/15/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/7/2009 60 Male 134 lb 6/30/2009 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 42 Male 222 lb 7/23/2009 United States
Primary
Concomitant
Decreased Appetite Hospitalization Male 7/30/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/1/2009 Female 8/6/2009 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 2/21/2008 Female 8/27/2009 Other Health Professional
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 6/1/2009 Female 8/27/2009 Other Health Professional
Primary
Secondary
Vision Blurred Disability 1/1/2009 65 Female 203 lb 8/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Parkinson's Disease Hospitalization Male 9/2/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Vision Blurred Disability 1/1/2009 65 Female 8/31/2009 United Kingdom
Primary
Concomitant
Purpura Other Serious 7/7/2009 75 Male 9/9/2009 Other Health Professional
Primary
Secondary
Concomitant
Weight Increased 12/1/2000 50 Male 275 lb 9/23/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 9/22/2008 75 Female 141 lb 9/28/2009 Consumer Brazil
Primary
Secondary
Concomitant
Renal Failure Acute Death 7/26/2009 82 Female 220 lb 9/28/2009 Other Health Professional Germany
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Vasculitis Other Serious 7/7/2009 75 Male 9/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 4/15/2008 60 Female 250 lb 9/24/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 62 Female 180 lb 9/28/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 60 Female 9/29/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 12/27/2006 Female 10/13/2009 Physician United States
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 8/1/2009 Male 10/14/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2000 60 Male 230 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Diarrhoea 9/1/2009 Female 10/16/2009 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2007 73 Female 180 lb 10/16/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 6/1/2009 59 Male 10/19/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Female 139 lb 11/5/2009 Physician United States
Primary
Concomitant
Asthma Other Serious 11/12/2009 Female 270 lb 12/1/2009 Physician United States
Primary
Concomitant
Hypomagnesaemia Other Serious 9/15/2009 61 Male 256 lb 12/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Female 139 lb 12/14/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/19/2009 79 Female 163 lb 1/6/2010 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Carcinoma Death 10/1/2009 65 Female 198 lb 1/11/2010 Physician Netherlands
Primary
Concomitant
Urticaria 43 Male 270 lb 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/1/2009 Female 196 lb 1/11/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 12/1/2008 Male 462 lb 1/12/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 12/28/2009 United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Female 139 lb 1/13/2010 Physician United States
Primary
Concomitant
Hypersensitivity Hospitalization 12/18/2009 79 Female 163 lb 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Femur Fracture Other Serious 5/1/2009 61 Female 250 lb 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Nausea Hospitalization 11/1/2009 44 Male 183 lb 1/22/2010 Physician Switzerland
Primary
Secondary
Concomitant
Vomiting Other Serious 8/3/2009 70 Female 154 lb 2/3/2010 Pharmacist Germany
Primary
Secondary
Concomitant

Drug Data