Lansoprazole combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urticaria Hospitalization 8/23/2005 49 Female 120 lb 1/10/2006 Physician Japan
Primary
Concomitant
Tremor Disability 9/10/2005 69 Male 1/10/2006 Physician United Kingdom
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 5/15/2005 68 Male 218 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 9/2/2005 50 Male 1/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Other Serious 1/1/1999 59 Female 161 lb 1/19/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 12/9/2004 Male 157 lb 2/9/2006 United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 9/15/2004 Male 174 lb 2/9/2006 United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 7/15/2005 Female 216 lb 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Chronic Hospitalization 11/18/2004 51 Female 2/16/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Mouth Haemorrhage Hospitalization 2/12/2006 Male 3/2/2006 Physician Japan
Primary
Concomitant
Interacting
Venous Pressure Jugular Increased Hospitalization 3/1/2000 78 Female 3/3/2006 Physician United Kingdom
Primary
Concomitant
Multi-organ Failure Life Threatening 2/14/2006 50 Female 3/7/2006 United Kingdom
Primary
Concomitant
Venous Thrombosis Other Serious 38 Female 4/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Alveolitis Hospitalization 4/1/2005 Female 231 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rash Macular Hospitalization 6/23/2006 Male 9/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Retinal Haemorrhage Other Serious 9/1/2006 60 Male 280 lb 2/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ulcer Hospitalization 3/1/2007 61 Female 5/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/1/2006 60 Male 5/13/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 86 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 1/7/2007 74 Female 8/13/2007 Other Health Professional Ireland
Primary
Secondary
Concomitant
Thrombosis Required Intervention 6/17/2007 35 Male 88 lb 6/20/2007 Pharmacist United States
Primary
Secondary
Concomitant
Liver Disorder Other Serious 4/5/2007 70 Male 9/27/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/11/2007 Female 143 lb 9/28/2007 Physician Japan
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 8/14/2007 58 Male 280 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 2/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 69 Male 181 lb 4/18/2008 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 8/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stomatitis Death 6/1/2008 80 Female 1/28/2009 Pharmacist Japan
Primary
Concomitant
Pulmonary Fibrosis Death 9/28/2008 Male 209 lb 2/10/2009 United Kingdom
Primary
Concomitant
Skin Discolouration Other Serious 1/27/2009 Female 185 lb 4/1/2009 Physician Ireland
Primary
Concomitant
Vomiting Hospitalization 1/9/2009 4/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/9/2009 4/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 10/16/2008 69 Male 226 lb 1/12/2009 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/29/2009 77 Male 5/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 5/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/9/2009 35 6/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 4/24/2009 48 Male 238 lb 5/6/2009 Pharmacist United States
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 64 Female 7/7/2009 United States
Primary
Concomitant
Interacting
Sepsis Other Serious 72 Female 8/12/2009 Physician United Kingdom
Primary
Concomitant
Pelvic Infection Required Intervention 6/23/2009 25 Female 178 lb 7/6/2009 Pharmacist United States
Primary
Concomitant
Mental Status Changes Required Intervention 5/27/2009 61 Female 192 lb 7/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Hospitalization 6/2/2009 Female 198 lb 7/5/2009 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 9/9/2009 Female 9/28/2009 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/9/2009 Female 10/5/2009 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/22/2009 70 Female 187 lb 10/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 8/13/2009 57 10/30/2009 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 12/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Hospitalization 11/20/2009 Female 130 lb 1/4/2010 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 1/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 68 Male 1/4/2010 United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 1/5/2010 Denmark
Primary
Concomitant
Tibia Fracture Other Serious 78 Female 1/15/2010
Primary
Secondary
Transient Ischaemic Attack Other Serious 2/24/2009 Female 1/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/24/2009 Female 1/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 2/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 3/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Disability 73 Female 3/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 4/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death Female 252 lb 4/22/2010 Other Health Professional United States
Primary
Concomitant
Hypotension Other Serious 85 Female 4/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Post Procedural Stroke Hospitalization 5/20/2009 65 Male 130 lb 4/28/2010 Pharmacist United States
Primary
Concomitant
Respiratory Disorder Life Threatening 2/9/2010 76 Male 93 lb 5/6/2010 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 84 Male 5/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Weight Decreased Other Serious 5/1/2000 35 Female 151 lb 5/7/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2000 35 Female 151 lb 5/11/2010 United States
Primary
Secondary
Concomitant
Enterovesical Fistula Hospitalization 1/19/2010 79 Male 150 lb 5/12/2010 Physician South Africa
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Disability 53 Male 126 lb 5/19/2010 Other Health Professional Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 4/5/2010 55 Male 123 lb 6/9/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Cirrhosis Hospitalization 9/19/2009 57 Female 117 lb 6/10/2010 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 6/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 2/1/2010 76 Female 143 lb 6/17/2010 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 10/7/2009 66 Male 241 lb 6/23/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 5/1/2000 35 Female 151 lb 6/24/2010 United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 10/7/2009 66 Male 241 lb 6/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 7/5/2010 United States
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 9/19/2009 57 Female 117 lb 7/9/2010 Physician Japan
Primary
Concomitant
Weight Decreased Life Threatening 5/10/2010 81 Male 7/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2007 53 Male 220 lb 7/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 6/4/2010 82 Male 7/15/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 11/1/2009 40 Female 252 lb 7/19/2010 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Other Serious 7/1/2006 53 Male 7/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Nephrogenic Systemic Fibrosis Disability 53 Male 126 lb 7/21/2010 Japan
Primary
Concomitant
Venous Thrombosis Other Serious 70 Female 112 lb 7/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2007 53 Male 220 lb 8/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Staphylococcal Infection Life Threatening 4/5/2010 55 Male 123 lb 8/23/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 8/25/2010 United States
Primary
Concomitant
Overdose Hospitalization 11/20/2009 79 Female 130 lb 9/8/2010 Physician Japan
Primary
Concomitant
Hypomagnesaemia Other Serious 58 Female 187 lb 9/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Immunoglobulin E Increased Death 6/15/2010 57 Male 10/12/2010 United Kingdom
Primary
Concomitant
Overdose Hospitalization 11/20/2009 79 Female 130 lb 10/21/2010 Physician Japan
Primary
Concomitant
Eyelid Oedema Other Serious 78 Female 10/25/2010 Pharmacist Canada
Primary
Concomitant
Pain In Extremity Hospitalization 8/31/2010 80 Male 148 lb 11/1/2010 Physician Japan
Primary
Concomitant
Interacting
Cardiac Arrest Death 6/14/2010 57 Male 11/1/2010 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 5/1/2000 35 Female 151 lb 11/15/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Female 11/18/2010 Pharmacist United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 9/1/2010 78 Female 236 lb 11/23/2010 Pharmacist Canada
Primary
Concomitant
Vomiting Other Serious 11/14/2010 80 Female 118 lb 12/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Other Serious 8/16/2010 69 Male 141 lb 12/6/2010 Pharmacist Japan
Primary
Concomitant
Urinary Tract Infection Other Serious Female 12/7/2010 Pharmacist United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/16/2010 77 Male 146 lb 12/13/2010 Pharmacist Japan
Primary
Concomitant
Muscle Spasms Other Serious 64 Female 12/10/2010 Pharmacist Denmark
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious 58 Female 12/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious 58 Female 12/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Other Serious 9/1/2010 78 Female 236 lb 12/30/2010 Pharmacist Canada
Primary
Concomitant
Protein-losing Gastroenteropathy Other Serious 8/16/2010 69 Male 141 lb 12/31/2010 Pharmacist Japan
Primary
Concomitant
Hypoalbuminaemia Hospitalization 8/16/2010 69 Male 141 lb 1/7/2011 Physician Japan
Primary
Concomitant
Muscle Spasms Other Serious 64 Female 1/14/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious Female 150 lb 1/20/2011 Consumer Canada
Primary
Concomitant
Abdominal Pain Other Serious 64 Female 1/10/2011 Pharmacist Denmark
Primary
Secondary
Concomitant
Anaemia Other Serious 8/1/2010 68 Female 90 lb 1/25/2011 Physician Japan
Primary
Secondary
Concomitant
Lung Abscess Death 10/8/2009 78 Female 110 lb 1/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Other Serious Female 1/31/2011 Physician Canada
Primary
Secondary
Concomitant
Pseudomembranous Colitis Hospitalization 6/16/2010 77 Male 146 lb 1/31/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/5/2011 Female 2/1/2011 Pharmacist United Kingdom
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 7/14/2010 57 Female 108 lb 2/1/2011 Physician United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 1/5/2011 Female 2/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 1/5/2011 Female 2/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Jc Virus Infection Life Threatening 4/5/2010 55 Male 123 lb 2/14/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/1/2010 54 Male 123 lb 2/17/2011 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 1/1/2011 79 Female 132 lb 2/22/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Ligament Rupture Disability 1/9/2011 45 Female 2/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Hospitalization 1/1/2011 79 Female 3/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Confusional State Disability 1/1/2011 79 Female 132 lb 3/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Organising Pneumonia Other Serious 9/1/2010 63 Female 165 lb 3/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/22/2011 79 Female 2/21/2011 Other Health Professional
Primary
Concomitant
Acidosis Death 9/1/2010 63 Female 165 lb 3/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 5/1/2000 35 Female 151 lb 3/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 7/1/2010 63 Female 165 lb 3/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Death 4/1/2010 63 Female 154 lb 3/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Hospitalization 12/1/2009 74 Female 3/30/2011 Pharmacist United States
Primary
Concomitant
Erythema Disability 5/11/2006 69 Male 202 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/13/2011 60 Female 238 lb 4/19/2011 Pharmacist United States
Primary
Concomitant
Malaise Other Serious 4/9/2011 77 Male 139 lb 5/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 7/29/2010 71 Female 84 lb 5/17/2011 Physician Japan
Primary
Concomitant
Pleural Effusion Other Serious 11/15/2010 73 Male 154 lb 5/19/2011 Pharmacist Japan
Primary
Concomitant
Sepsis Death 12/14/2010 91 Female 140 lb 5/23/2011 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 3/19/2011 61 Male 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Death Hospitalization 5/27/2010 57 Female 126 lb 5/30/2011 Physician Japan
Primary
Concomitant
Granulocyte Count Decreased Hospitalization 3/19/2011 61 Male 6/3/2011 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 7/29/2010 71 Female 84 lb 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Urticaria Other Serious 5/1/2011 68 Male 90 lb 6/30/2011 Physician Japan
Primary
Concomitant
Urticaria Other Serious 5/1/2011 68 Male 90 lb 7/10/2011 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Hospitalization 5/27/2010 57 Female 126 lb 7/21/2011 Physician Japan
Primary
Concomitant
Off Label Use Other Serious 5/1/2011 68 Male 90 lb 7/29/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 6/30/2009 68 Female 106 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Colitis Microscopic Hospitalization 68 Male 8/5/2011 Other Health Professional Japan
Primary
Secondary
Myocardial Infarction Death 4/29/2011 74 Female 8/9/2011 Physician United Kingdom
Primary
Concomitant
Infection Other Serious 6/28/2011 78 Female 99 lb 8/30/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 1/13/2011 74 Female 9/13/2011 Physician Japan
Primary
Concomitant

Drug Data