Lansoprazole combined with Valproate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Ulcer Hospitalization 2/13/2002 Female 1/4/2006 France
Primary
Concomitant
Aneurysm Death 43 Male 1/11/2006 United States
Primary
Concomitant
Fatigue Hospitalization 9/13/2005 56 Female 185 lb 12/27/2005 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 5/27/2005 76 Female 77 lb 4/24/2006 Physician Japan
Primary
Concomitant
Suicide Attempt Life Threatening 4/14/2006 47 Male 228 lb 5/22/2006 United States
Primary
Secondary
Concomitant
Vascular Calcification Hospitalization 2/11/2006 62 Female 6/6/2006 France
Primary
Concomitant
Granulocytopenia Required Intervention 1/18/2006 46 Female 3/22/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/27/2005 33 Male 3/7/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/1/2005 34 Male 2/24/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/6/2006 32 Female 254 lb 10/13/2006 Physician United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 11/1/2006 43 Female 179 lb 4/9/2007 Physician United Kingdom
Primary
Concomitant
Oxygen Saturation Decreased Life Threatening 4/16/2007 57 Male 4/27/2007 Physician Japan
Primary
Concomitant
Oxygen Saturation Decreased Life Threatening 4/16/2007 57 Male 154 lb 5/15/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/4/2007 55 Male 189 lb 5/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Internal Diameter Abnormal Hospitalization 54 Male 8/1/2007 Physician Finland
Primary
Concomitant
Diabetes Mellitus Hospitalization 6/21/2007 Male 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/24/2007 55 Male 150 lb 8/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 6/21/2007 Male 8/27/2007 Physician Japan
Primary
Secondary
Concomitant
Status Epilepticus Life Threatening 6/10/2007 19 Male 8/30/2007 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 1/8/2008 40 Male 3/20/2008 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 1/8/2008 40 Male 5/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious Male 6/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 6/2/2000 51 Female 6/18/2008 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 Female 7/11/2008 Physician United Kingdom
Primary
Concomitant
Somnolence Other Serious 7/10/2008 60 Male 7/21/2008 Physician Guatemala
Primary
Concomitant
Troponin Increased Hospitalization 8/12/2008 Male 210 lb 8/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 8/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 8/12/2008 Male 210 lb 8/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 8/12/2008 Male 210 lb 9/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 8/12/2008 Male 210 lb 9/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 9/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Hospitalization 6/1/2008 Male 10/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ultrasound Scan Abnormal Other Serious 6/24/2008 Male 10/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Scleritis Disability 89 Female 10/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Scleritis Disability 89 Female 11/11/2008 United Kingdom
Primary
Concomitant
Dysphagia Other Serious Male 11/20/2008 Pharmacist United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 6/10/2008 38 Male 278 lb 11/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Dysphagia Other Serious Male 11/24/2008 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 6/24/2008 31 Male 12/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hemiparesis Other Serious 5/1/2004 Male 12/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 31 Male 12/22/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 1/18/2009 65 Male 223 lb 2/9/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/2/2009 72 Male 2/9/2009 Israel
Primary
Secondary
Concomitant
Ammonia Increased 3/4/2009 Pharmacist United States
Primary
Concomitant
Thoracic Vertebral Fracture Other Serious 11/1/2008 Female 3/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 2/3/2009 25 Male 3/4/2009 Other Health Professional Japan
Primary
Concomitant
Vision Blurred Other Serious 11/25/2008 Male 205 lb 3/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Grand Mal Convulsion Hospitalization 3/3/2009 42 Female 223 lb 3/24/2009 United Kingdom
Primary
Concomitant
Urticaria Other Serious 1/1/1998 36 Male 4/1/2009 Consumer France
Primary
Secondary
Concomitant
Interacting
Pleural Effusion Other Serious 2/3/2009 25 Male 3/27/2009 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Life Threatening 8/27/2008 18 Male 104 lb 4/6/2009 Japan
Primary
Concomitant
Treatment Noncompliance Other Serious 4/6/2009 Male 386 lb 5/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 3/3/2009 42 Female 6/2/2009 United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 2/3/2009 25 Male 6/3/2009 Other Health Professional Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 70 Male 6/5/2009 United States
Primary
Concomitant
Pyrexia Hospitalization 1/22/2009 69 Female 6/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Life Threatening 8/27/2008 18 Male 104 lb 6/22/2009 Japan
Primary
Concomitant
Weight Increased Other Serious 5/22/2009 Female 6/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Other Serious 6/21/2009 Female 7/20/2009 Physician United Kingdom
Primary
Concomitant
Completed Suicide Death 5/21/2009 Male 7/24/2009 Physician United Kingdom
Primary
Concomitant
Burning Sensation Other Serious 7/9/2009 51 Female 227 lb 8/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 7/9/2009 51 Female 227 lb 8/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/18/2009 69 Female 105 lb 8/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 7/9/2009 51 Female 227 lb 8/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Burning Sensation Other Serious 7/9/2009 51 Female 227 lb 8/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 7/9/2009 51 Female 8/19/2009 United Kingdom
Primary
Concomitant
Hyponatraemia Other Serious 7/9/2009 51 Female 227 lb 8/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Burning Sensation Other Serious 7/9/2009 51 Female 227 lb 8/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Burning Sensation Other Serious 7/9/2009 51 Female 227 lb 9/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 8/22/2009 54 Male 9/11/2009 Physician Austria
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 4/6/2009 60 Male 386 lb 10/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/4/2009 Male 10/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/20/2008 35 Male 10/26/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/4/2009 Male 12/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/4/2009 Male 12/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 9/7/2009 Male 12/31/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 5/18/2009 69 Female 105 lb 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Flow Decreased Other Serious 3/1/2008 Male 2/4/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/21/2009 55 Female 4/22/2010 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 6/25/2009 32 Male 4/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 6/25/2009 32 Male 5/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Death 5/16/2010 65 Female 6/7/2010 Physician United Kingdom
Primary
Concomitant
Pneumonia Death 5/16/2010 65 Female 6/21/2010 Physician United Kingdom
Primary
Concomitant
Sedation Other Serious 6/14/2010 45 Female 7/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Neutropenic Sepsis Hospitalization 6/15/2010 83 Male 7/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenic Sepsis Hospitalization 6/15/2010 83 Male 7/12/2010 Other Health Professional France
Primary
Concomitant
Sedation Other Serious 6/14/2010 45 Female 7/23/2010 Physician United Kingdom
Primary
Concomitant
Interacting
Wound Secretion Hospitalization 8/12/2008 Male 210 lb 7/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Sedation Other Serious 6/14/2010 45 Female 7/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sedation Other Serious 6/14/2010 45 Female 7/29/2010 United Kingdom
Primary
Secondary
Concomitant
Sedation Other Serious 45 Female 7/30/2010 Germany
Primary
Secondary
Concomitant
Sedation Other Serious 6/14/2010 45 Female 8/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Flow Decreased Other Serious 7/1/2008 21 Male 8/12/2010 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 66 Female 9/2/2010 Consumer United Kingdom
Primary
Concomitant
Thymol Turbidity Test Increased Other Serious 6/7/2010 33 Male 9/29/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/28/2010 51 Male 243 lb 10/18/2010 Physician United Kingdom
Primary
Concomitant
Thymol Turbidity Test Increased Other Serious 6/7/2010 33 Male 11/10/2010 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 1/17/2010 Male 168 lb 11/22/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 9/12/2010 32 Female 209 lb 11/30/2010 Pharmacist United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 9/12/2010 32 Female 209 lb 12/20/2010 Pharmacist United Kingdom
Primary
Concomitant
Hyperlipidaemia Other Serious 6/7/2010 33 Male 12/16/2010 Physician Japan
Primary
Concomitant
Oesophageal Carcinoma Death 7/1/2010 62 Female 1/28/2011 Other Health Professional Ireland
Primary
Concomitant
Tachycardia Other Serious 5/25/2010 27 Male 4/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Petechiae Hospitalization 1/23/2011 59 Male 4/13/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperpyrexia Hospitalization 10/26/2010 56 Female 4/20/2011 Physician Ireland
Primary
Concomitant
Pneumonia Aspiration Hospitalization 3/31/2011 68 Female 5/6/2011 Physician Japan
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 3/31/2011 68 Female 5/6/2011 Physician Japan
Primary
Concomitant
Convulsion Hospitalization 4/17/2011 66 Male 144 lb 5/10/2011 Physician Japan
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 10/26/2010 56 Female 5/13/2011 Physician Ireland
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization Male 5/3/2011 Pharmacist Ireland
Primary
Concomitant
Drug Ineffective Other Serious 2/1/2010 62 Male 6/2/2011 Physician United Kingdom
Primary
Concomitant
Decreased Appetite Hospitalization 1/17/2010 55 Male 168 lb 6/6/2011 Consumer Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/17/2010 55 Male 168 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Epididymitis Other Serious 6/24/2008 31 Male 6/8/2011 Physician United Kingdom
Primary
Concomitant
Convulsion Life Threatening Female 6/13/2011 Pharmacist United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Life Threatening 7/12/2004 39 Female 6/14/2011 Consumer United Kingdom
Primary
Concomitant
Electrocardiogram Abnormal Hospitalization 5/10/2006 39 Female 190 lb 6/14/2011 Consumer United Kingdom
Primary
Concomitant
Kidney Infection Hospitalization Male 6/9/2011 Pharmacist Ireland
Primary
Concomitant
Hypophosphataemia Disability 10/1/2008 15 Female 6/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Other Serious 1/1/2011 47 Male 6/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diabetes Mellitus Life Threatening Female 6/29/2011 Pharmacist United Kingdom
Primary
Concomitant
Anticonvulsant Drug Level Decreased Hospitalization 58 Female 7/11/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/1/2011 47 Male 7/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/1/2011 47 Male 8/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2011 47 Male 8/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious Male 8/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Altered State Of Consciousness Life Threatening 8/13/2011 33 Male 9/7/2011 Physician Japan
Primary
Concomitant
Convulsion Hospitalization 7/1/2011 2 Male 9/12/2011 Physician Ireland
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 1/1/2011 47 Male 9/12/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 7/1/2011 2 Male 9/22/2011 Physician Ireland
Primary
Concomitant
Neutrophil Count Decreased Other Serious 7/1/2011 30 Male 9/30/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/1/2011 47 Male 9/30/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Abdominal Pain Upper Other Serious 7/1/2011 30 Male 10/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 11/4/2010 56 Male 148 lb 10/10/2011 Physician United Kingdom
Primary
Concomitant
Dehydration Other Serious 10/1/2008 15 Female 10/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Abdominal Pain Upper Other Serious 7/1/2011 30 Male 10/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/9/2011 27 Female 10/13/2011 Physician
Primary
Secondary
Concomitant
Death Death Male 10/19/2011 Physician Ireland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2011 30 Male 10/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/9/2011 27 Female 10/18/2011 Physician
Primary
Secondary
Concomitant
Muscle Rigidity Hospitalization 1/1/2011 47 Male 10/24/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hallucination Other Serious 9/21/2011 46 Female 11/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 8/1/2011 33 Male 132 lb 11/10/2011 Physician Japan
Primary
Concomitant
Interacting
Psychotic Disorder Other Serious 45 Female 11/14/2011 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing Other Serious 9/4/2011 58 Male 11/18/2011 Physician Japan
Primary
Concomitant
Mania Hospitalization 2/1/2011 47 Male 187 lb 11/21/2011 Physician Ireland
Primary
Concomitant
Hypoalbuminaemia Other Serious 5/24/2011 50 Male 128 lb 12/7/2011 Physician Japan
Primary
Concomitant
Oral Discomfort Other Serious 7/28/2011 65 Male 12/9/2011 Physician Japan
Primary
Concomitant
Neutropenia Other Serious 1/1/2011 47 Male 12/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Prerenal Failure Hospitalization 76 Male 12/19/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data