Lansoprazole combined with Sodium Bicarbonate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tonic Convulsion Hospitalization 10/6/2005 66 Male 152 lb 12/29/2005 Pharmacist Japan
Primary
Concomitant
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Extrasystoles Other Serious 12/1/2005 Male 1/20/2006 Physician Sweden
Primary
Concomitant
Tonic Convulsion Hospitalization 10/6/2005 66 Male 152 lb 1/12/2006 Pharmacist Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2005 Male 5/8/2006 Physician Sweden
Primary
Concomitant
Renal Failure Disability 12/27/2005 Male 6/1/2006 Physician Japan
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 12/1/2005 Male 6/6/2006 Physician Sweden
Primary
Concomitant
Renal Failure Hospitalization 12/27/2005 Male 6/15/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/2/2006 66 198 lb 7/11/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2006 Male 7/19/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Other Serious 7/26/2005 52 Female 7/24/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2005 Male 8/21/2006 Physician Sweden
Primary
Concomitant
Vomiting Disability 9/7/2006 77 Male 10/16/2006 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Disability 9/7/2006 77 Male 11/2/2006 Physician Japan
Primary
Secondary
Concomitant
Oedema Hospitalization 6/7/2006 58 Male 11/10/2006 United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 9/7/2006 77 Male 11/29/2006 Physician Japan
Primary
Secondary
Concomitant
Vascular Bypass Graft Other Serious 7/21/2005 Male 216 lb 12/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Vessel Disorder Other Serious 6/14/2004 52 Male 178 lb 12/6/2006 United States
Primary
Concomitant
Sputum Culture Positive Life Threatening 11/20/2006 68 Male 12/12/2006 Japan
Primary
Secondary
Concomitant
Death Other Serious 11/12/2006 Male 216 lb 12/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sputum Culture Positive Life Threatening 11/20/2006 68 Male 12/27/2006 Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious 11/12/2006 Male 216 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tenderness Other Serious 1/1/2003 19 Male 1/12/2007 Physician United States
Primary
Concomitant
Mycobacterium Avium Complex Infection Death 1/13/2007 Male 121 lb 2/21/2007 United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 2/19/2007 Physician Japan
Primary
Concomitant
Peripheral Ischaemia Other Serious 7/21/2005 Male 216 lb 2/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/5/2007 Physician Japan
Primary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/16/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious Male 216 lb 4/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 4/2/2007 63 Male 6/11/2007 Physician Japan
Primary
Concomitant
Troponin I Increased Other Serious 2/25/2007 61 Female 148 lb 6/8/2007 Pharmacist United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 9/20/2005 59 Male 143 lb 7/13/2007 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 5/23/2007 Male 110 lb 7/18/2007 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Disability 2/14/2007 67 Female 121 lb 7/13/2007 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 5/23/2007 Male 110 lb 8/6/2007 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 2/14/2007 67 Female 121 lb 8/6/2007 Physician Japan
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 5/15/2007 Male 165 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 12/7/2004 Male 178 lb 3/3/2008 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 9/10/2007 58 Male 126 lb 3/28/2008 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 2/20/2007 63 Male 3/31/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/4/2007 71 Female 126 lb 6/23/2008 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious 1/4/2007 71 Female 126 lb 7/9/2008 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Other Serious 5/19/2008 Female 110 lb 7/16/2008 Physician Denmark
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 41 8/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 8/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 41 8/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Toxicity Life Threatening 1/3/2006 58 Male 8/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Maculo-papular Hospitalization 7/26/2008 9/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Other Serious 5/19/2008 Female 110 lb 9/8/2008 Physician Denmark
Primary
Concomitant
Proteinuria Other Serious 8/22/2008 Female 132 lb 10/20/2008 Physician United Kingdom
Primary
Concomitant
Shock Other Serious 11/23/2008 76 Male 185 lb 1/9/2009 Other Health Professional Canada
Primary
Concomitant
Renal Impairment Life Threatening 6/26/2008 49 4/6/2009 Physician Japan
Primary
Secondary
Concomitant
Haemolysis Hospitalization 2/4/2009 Female 115 lb 4/21/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/14/2009 69 Male 5/29/2009 Physician Japan
Primary
Concomitant
Transmission Of An Infectious Agent Via A Medicinal Product Hospitalization 1/1/2005 87 Female 5/27/2009 United Kingdom
Primary
Secondary
Concomitant
Arthritis Disability 2/1/2009 40 Female 6/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/14/2009 69 Male 6/4/2009 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 5/29/2009 67 6/8/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 87 Female 6/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Hospitalization 87 Female 6/8/2009
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 5/29/2009 67 6/12/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2005 6/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 87 Female 6/10/2009 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2005 78 6/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 5/29/2009 67 6/19/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 5/29/2009 67 7/6/2009 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/14/2009 68 Male 7/16/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/14/2009 68 Male 7/30/2009 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2005 78 Female 8/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 5/29/2009 67 Male 126 lb 12/16/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Schizophrenia, Catatonic Type Other Serious 2/1/2008 57 Male 12/16/2009 United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 11/27/2007 58 Female 123 lb 2/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 3/5/2010 Male 3/18/2010 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Somnambulism Life Threatening 5/1/2010 Female 140 lb 6/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Convulsion Hospitalization 3/5/2010 2 Male 7/9/2010 Pharmacist United States
Primary
Concomitant
Renal Transplant Hospitalization 6/6/2010 47 Female 7/23/2010 United States
Primary
Concomitant
Renal Failure Other Serious 4/30/2008 15 Female 88 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/16/2008 41 Male 225 lb 8/23/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 1/16/2008 41 Male 225 lb 9/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 12/3/2009 35 Female 9/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Dermatitis Exfoliative Hospitalization 10/1/2010 60 Female 10/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dermatitis Exfoliative Hospitalization 10/1/2010 60 Female 10/25/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 11/10/2010 79 Female 11/18/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 11/22/2010 Lawyer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 48 Female 115 lb 1/6/2011 Physician Japan
Primary
Concomitant
Blood Pressure Increased Other Serious 8/9/2009 48 Female 115 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 11/1/2010 63 Female 1/10/2011 Other Health Professional Norway
Primary
Concomitant
Cerebral Infarction Hospitalization 5/29/2009 67 Male 126 lb 1/31/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 11/1/2010 63 Female 3/3/2011 Other Health Professional Norway
Primary
Concomitant
Hyperuricaemia Death 11/10/2010 79 Female 97 lb 3/9/2011 Physician Japan
Primary
Concomitant
Screaming Other Serious 12/21/2010 1 Female 3/2/2011 Consumer United States
Primary
Secondary
Hyponatraemia Death 11/10/2010 79 Female 97 lb 4/5/2011 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 4/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Emotional Distress Other Serious 9/18/2002 77 Male 135 lb 5/10/2011 Lawyer United States
Primary
Concomitant
Pneumonia Aspiration Death 3/20/2010 73 Female 5/18/2011 Physician Japan
Primary
Concomitant
Renal Failure Disability 5/25/2008 4 Male 37 lb 5/19/2011 Physician Japan
Primary
Secondary
Concomitant
Anxiety Death 3/27/2001 76 Male 203 lb 5/25/2011 Other Health Professional United States
Primary
Concomitant
C-reactive Protein Increased Hospitalization 12/20/2010 60 Female 6/10/2011 Physician Japan
Primary
Concomitant
Tibia Fracture Other Serious 3/20/2010 73 Female 6/22/2011 Other Health Professional Japan
Primary
Concomitant
Arthralgia Hospitalization 4/22/2011 27 Female 6/24/2011 Consumer France
Primary
Secondary
Concomitant
Death Death Male 245 lb 6/29/2011 Other Health Professional United States
Primary
Concomitant
Sepsis Disability 3/19/2011 75 Male 6/29/2011 Other Health Professional Japan
Primary
Concomitant
Erythema Hospitalization 4/22/2011 27 Female 7/12/2011 Physician France
Primary
Secondary
Concomitant
Hyperuricaemia Hospitalization 2/14/2009 68 Male 7/13/2011 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 1/24/2011 67 Male 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/2/2009 73 Female 192 lb 7/20/2011 Consumer United Kingdom
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 6/18/2010 61 Female 97 lb 7/26/2011 Other Health Professional Japan
Primary
Concomitant
Hyperkalaemia Death 5/27/2009 74 Female 106 lb 7/28/2011 Physician Japan
Primary
Concomitant
Encephalitis Fungal Death Male 139 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Fungaemia Death 6/22/2005 46 Male 126 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Death Death 5/6/2011 38 Female 8/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Cryptococcosis Other Serious 9/10/2008 58 Female 134 lb 8/5/2011 Physician Japan
Primary
Secondary
Concomitant
Congestive Cardiomyopathy Disability 5/25/2008 4 Male 37 lb 8/26/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 11/24/2010 63 Male 9/15/2011 Physician Japan
Primary
Secondary
Concomitant
Haemorrhagic Cerebral Infarction Death 3/18/2011 75 Male 9/19/2011 Other Health Professional Japan
Primary
Concomitant
Graft Versus Host Disease Disability 6/6/2011 13 Female 88 lb 9/20/2011 Physician Japan
Primary
Concomitant
Retroperitoneal Haemorrhage Death 5/6/2011 38 Female 10/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 6/22/2010 10/26/2011 Physician Japan
Primary
Concomitant
Visual Impairment Death 6/6/2011 13 Female 88 lb 11/8/2011 Physician Japan
Primary
Concomitant
Skin Ulcer Hospitalization 12/1/2010 32 Female 84 lb 11/8/2011 Physician Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 2/11/2011 55 Female 123 lb 11/11/2011 Physician Japan
Primary
Concomitant
Anaemia Haemolytic Autoimmune Hospitalization 4/8/2011 80 Male 112 lb 11/14/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchiolitis Hospitalization 9/23/2011 79 Male 126 lb 11/16/2011 Physician Japan
Primary
Secondary
Concomitant
Melaena Other Serious 5/21/2011 54 Male 12/2/2011 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 7/2/2010 71 Female 104 lb 12/6/2011 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 6/22/2010 12/8/2011 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening Female 12/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 1/24/2011 67 Male 12/12/2011 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 2/7/2009 57 Male 139 lb 12/14/2011 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 11/12/2011 79 Male 121 lb 12/28/2011 Physician Japan
Primary
Concomitant
Anaemia Death 5/9/2011 74 Female 99 lb 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 1/24/2011 67 Male 1/13/2012 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 5/1/2011 64 Male 108 lb 1/13/2012 Physician Japan
Primary
Secondary
Concomitant
Hypertensive Encephalopathy Hospitalization 12/3/2011 74 Female 95 lb 1/19/2012 Physician Japan
Primary
Concomitant

Drug Data