Lansoprazole combined with Sennoside

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Subcutaneous Nodule 11/25/2005 53 Male 2/6/2006 Japan
Primary
Concomitant
Subcutaneous Nodule 11/25/2005 53 Male 2/22/2006 Japan
Primary
Concomitant
Restlessness Hospitalization 10/1/2006 63 Male 11/6/2006 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 10/16/2006 54 Female 77 lb 1/5/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/16/2006 54 Female 100 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/16/2006 54 Female 100 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 5/2/2007 43 Female 6/4/2007 Consumer Canada
Primary
Concomitant
Myocardial Infarction Other Serious 5/2/2007 43 Female 6/11/2007 Consumer Canada
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2007 43 Female 6/20/2007 Consumer Canada
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2007 43 Female 6/20/2007 Consumer Canada
Primary
Concomitant
Completed Suicide Death 5/8/2007 84 Female 95 lb 7/13/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/23/2007 Male 110 lb 7/18/2007 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 9/23/2006 70 Male 7/20/2007 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/18/2006 70 Male 7/18/2007 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 9/1/2006 70 Male 7/24/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 9/1/2006 70 Male 7/26/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Completed Suicide Death 5/8/2007 84 Female 95 lb 7/27/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 3/20/2007 79 Male 104 lb 7/27/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Completed Suicide Death 5/8/2007 84 Female 95 lb 7/30/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 9/23/2006 70 Male 132 lb 7/31/2007 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 9/23/2006 70 Male 7/31/2007 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/18/2006 70 Male 7/24/2007 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 9/23/2006 70 Male 132 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/23/2007 Male 110 lb 8/6/2007 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 9/23/2006 70 Male 8/6/2007 Physician Japan
Primary
Secondary
Stevens-johnson Syndrome Death 9/23/2006 70 Male 8/7/2007 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/18/2006 70 Male 8/21/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2007 70 Male 9/17/2007 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/31/2007 70 Male 119 lb 9/28/2007 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/31/2007 70 Male 119 lb 10/2/2007 Physician Japan
Primary
Concomitant
Mouth Haemorrhage Hospitalization 10/23/2007 85 Male 11/26/2007 Japan
Primary
Concomitant
Renal Failure Hospitalization 10/23/2007 85 Male 12/11/2007 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2007 56 Male 137 lb 3/27/2008 Physician Japan
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 6/1/2006 44 Male 6/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 6/8/2004 42 Male 10/20/2008 Physician Japan
Primary
Secondary
Concomitant
Abnormal Behaviour Other Serious 8/1/2008 Male 112 lb 10/27/2008 Physician Japan
Primary
Concomitant
Thrombosis Other Serious 11/15/2008 Female 1/6/2009 Physician Canada
Primary
Concomitant
Renal Failure Acute Other Serious 9/16/2008 85 Female 12/29/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 9/16/2008 85 Female 2/17/2009 Physician Japan
Primary
Secondary
Concomitant
Myalgia Other Serious 11/13/2008 Female 3/12/2009 Physician Canada
Primary
Concomitant
Deep Vein Thrombosis Other Serious 3/31/2009 62 Female 4/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 3/31/2009 62 Female 5/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 3/26/2009 62 Female 5/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 3/26/2009 62 Female 6/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Life Threatening 2/17/2009 60 Female 6/8/2009 Other Health Professional Japan
Primary
Concomitant
Wheezing Other Serious 3/26/2009 62 Female 7/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 9/16/2008 86 Female 7/28/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/1/2009 Male 8/12/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 9/10/2008 Female 134 lb 11/3/2009 Physician Japan
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 9/16/2009 57 Male 130 lb 1/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Death 9/16/2009 Male 1/19/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/10/2009 Female 104 lb 3/4/2010 Physician Japan
Primary
Concomitant
Rib Fracture Hospitalization 5/7/2009 Male 3/15/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Other Serious 2/3/2009 Male 3/16/2010 Physician Japan
Primary
Concomitant
Metastases To Liver Life Threatening 11/25/2009 70 Female 4/9/2010 Japan
Primary
Concomitant
Tremor Hospitalization 3/22/2010 82 Female 4/15/2010 Physician Japan
Primary
Concomitant
Metastases To Liver Life Threatening 11/25/2009 70 Female 4/23/2010 Japan
Primary
Concomitant
Tremor Hospitalization 3/22/2010 82 Female 4/29/2010 Physician Japan
Primary
Concomitant
Metastases To Liver Life Threatening 11/25/2009 70 Female 5/7/2010 Japan
Primary
Concomitant
Metastases To Liver Life Threatening 11/25/2009 70 Female 6/18/2010 Physician Japan
Primary
Concomitant
Tremor Hospitalization 3/22/2010 82 Female 6/18/2010 Physician Japan
Primary
Concomitant
Parkinsonism Other Serious 2/2/2010 75 Female 7/6/2010 Physician Japan
Primary
Concomitant
Metastases To Liver Life Threatening 11/25/2009 70 Female 8/17/2010 Physician Japan
Primary
Concomitant
Gastric Cancer Hospitalization 6/22/2010 70 Female 8/26/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/22/2010 65 Female 8/30/2010 Physician Japan
Primary
Concomitant
Visual Impairment Hospitalization 7/22/2010 65 Female 9/20/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/10/2009 74 Female 104 lb 9/24/2010 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 4/28/2010 19 Female 115 lb 11/8/2010 Physician Japan
Primary
Concomitant
Urine Output Decreased Other Serious 10/5/2010 86 Male 11/19/2010 Japan
Primary
Concomitant
Urine Output Decreased Other Serious 10/5/2010 86 Male 12/16/2010 Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/29/2009 53 Female 159 lb 1/10/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Other Serious 10/5/2010 86 Male 1/24/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Death 11/28/2010 81 Female 1/25/2011 Physician Japan
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/11/2011 70 Male 132 lb 2/14/2011 Consumer Germany
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 1/11/2011 70 Male 132 lb 3/4/2011 Consumer Germany
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 9/20/2010 77 Female 101 lb 4/7/2011 Physician Japan
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 1/11/2011 70 Male 132 lb 4/8/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/3/2011 61 Male 121 lb 4/13/2011 Physician Japan
Primary
Concomitant
Streptococcus Test Positive Other Serious 12/1/2010 78 Female 88 lb 4/15/2011 Physician Japan
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/11/2011 70 Male 132 lb 4/27/2011 Consumer Germany
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 1/11/2011 70 Male 132 lb 4/28/2011 Consumer Germany
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 1/11/2011 70 Male 132 lb 5/17/2011 Consumer Germany
Primary
Secondary
Concomitant
Anaemia Hospitalization 9/9/2010 77 Male 103 lb 5/17/2011 Physician Japan
Primary
Secondary
Concomitant
Phlebitis Hospitalization 5/1/2011 5/19/2011 Consumer Canada
Primary
Concomitant
Hypophagia Hospitalization 12/1/2010 78 Female 88 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Dementia Alzheimer's Type Hospitalization 6/21/2010 70 Female 5/25/2011 Physician Japan
Primary
Concomitant
Thrombosis In Device Hospitalization 4/21/2011 74 Male 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 6/21/2010 70 Female 6/7/2011 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Hospitalization 12/20/2010 60 Female 6/10/2011 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/21/2010 70 Female 6/15/2011 Physician Japan
Primary
Concomitant
Serum Sickness Death 7/16/2010 68 Male 121 lb 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 2/10/2011 75 Female 6/17/2011 Physician Japan
Primary
Concomitant
Oesophageal Candidiasis Hospitalization 3/16/2011 69 Male 121 lb 6/17/2011 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/21/2010 70 Female 6/20/2011 Physician Japan
Primary
Concomitant
Drug Eruption Hospitalization 1/3/2011 61 Male 121 lb 6/22/2011 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/21/2010 70 Female 7/6/2011 Physician Japan
Primary
Concomitant
Asthenia Hospitalization 1/28/2011 78 Male 132 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 3/16/2011 69 Male 121 lb 7/14/2011 Physician Japan
Primary
Concomitant
Dehydration Hospitalization 1/28/2011 78 Male 132 lb 7/27/2011 Physician Japan
Primary
Secondary
Concomitant
Dementia Hospitalization 6/21/2010 70 Female 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Cryptococcosis Other Serious 9/10/2008 58 Female 134 lb 8/5/2011 Physician Japan
Primary
Secondary
Concomitant
Pruritus 3/1/2011 65 Male 8/9/2011 Pharmacist Japan
Primary
Concomitant
Hypoglycaemia Hospitalization 2/10/2011 75 Female 8/10/2011 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 7/6/2011 86 Female 8/12/2011 Physician Japan
Primary
Concomitant
Melaena Other Serious 7/17/2011 Female 8/19/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 6/26/2011 93 Male 8/22/2011 Other Health Professional Japan
Primary
Concomitant
Melaena Hospitalization 7/16/2011 92 Female 8/29/2011 Physician Japan
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 9/20/2010 77 Female 101 lb 8/30/2011 Physician Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 8/17/2011 82 Female 8/31/2011 Pharmacist Japan
Primary
Concomitant
Abdominal Pain Upper Other Serious 1/11/2007 65 Male 112 lb 9/7/2011 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 7/6/2011 86 Female 88 lb 9/7/2011 Physician Japan
Primary
Concomitant
Sepsis Death 6/26/2011 93 Male 9/20/2011 Other Health Professional Japan
Primary
Concomitant
Blood Potassium Increased Life Threatening 8/26/2011 75 Male 77 lb 9/20/2011 Pharmacist Japan
Primary
Concomitant
Blood Potassium Increased Life Threatening 8/26/2011 75 Male 77 lb 9/22/2011 Physician Japan
Primary
Concomitant
Palpitations Other Serious 8/26/2011 73 Female 9/30/2011 Physician Japan
Primary
Concomitant
Urticaria Hospitalization 6/3/2011 72 Female 10/7/2011 Physician Japan
Primary
Concomitant
Asthenia Other Serious 8/26/2011 73 Female 10/13/2011 Japan
Primary
Concomitant
Dementia Hospitalization 6/21/2010 70 Female 10/19/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Hospitalization 6/3/2011 72 Female 10/19/2011 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/6/2011 86 Female 88 lb 10/28/2011 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/6/2011 86 Female 88 lb 11/4/2011 Physician Japan
Primary
Concomitant
Gastric Cancer Hospitalization 6/22/2010 70 Female 11/8/2011 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 6/3/2011 72 Female 11/10/2011 Physician Japan
Primary
Concomitant
Dementia Hospitalization 6/21/2010 70 Female 11/17/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/7/2011 64 Male 176 lb 11/18/2011 Physician Denmark
Primary
Secondary
Concomitant
Abdominal Pain Upper Other Serious 58 Male 250 lb 11/17/2011 Consumer Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/6/2011 86 Female 88 lb 11/28/2011 Physician Japan
Primary
Concomitant
Infection Disability 4/28/2010 19 Female 115 lb 11/29/2011 Physician Japan
Primary
Concomitant
Blood Magnesium Increased Other Serious 1/1/2011 47 Female 11/18/2011 Other Health Professional Japan
Primary
Concomitant
Muscle Rupture Hospitalization 5/7/2011 64 Male 179 lb 12/1/2011 Physician Denmark
Primary
Secondary
Concomitant
Hypoalbuminaemia Other Serious 5/24/2011 50 Male 128 lb 12/7/2011 Physician Japan
Primary
Concomitant
Muscle Rupture Hospitalization 5/7/2011 64 Male 179 lb 12/14/2011 Physician Denmark
Primary
Secondary
Concomitant
Muscle Atrophy Other Serious 58 Male 250 lb 12/19/2011 Consumer Canada
Primary
Concomitant
Swelling Hospitalization 10/4/2011 70 Male 119 lb 1/2/2012 Pharmacist Japan
Primary
Concomitant
Pneumonia Hospitalization 5/7/2011 64 Male 179 lb 1/3/2012 Physician Denmark
Primary
Secondary
Concomitant
Death Death 12/24/2011 79 Male 91 lb 1/9/2012 Physician Japan
Primary
Concomitant
Death Death 12/26/2011 77 Female 115 lb 1/10/2012 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/18/2010 81 Male 117 lb 1/23/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Hospitalization 9/16/2011 78 Male 121 lb 1/25/2012 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/6/2011 86 Female 88 lb 1/31/2012 Physician Japan
Primary
Concomitant
Lymph Node Pain Hospitalization 10/4/2011 70 Male 119 lb 2/3/2012 Pharmacist Japan
Primary
Concomitant
Pneumonia Death 12/24/2011 79 Male 91 lb 2/8/2012 Physician Japan
Primary
Concomitant
Pneumonia Death 1/1/2011 77 Female 115 lb 2/9/2012 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 12/25/2011 77 Female 115 lb 2/16/2012 Physician Japan
Primary
Concomitant
Blood Cholesterol Decreased Other Serious 6/18/2010 81 Male 117 lb 2/22/2012 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 5/7/2009 70 Male 3/19/2012 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Disability 4/28/2010 19 Female 115 lb 3/21/2012 Physician Japan
Primary
Concomitant
Hypoalbuminaemia Other Serious 8/19/2009 65 Female 121 lb 3/23/2012 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 8/19/2009 65 Female 121 lb 3/26/2012 Physician Japan
Primary
Concomitant
Bursitis Death 5/7/2009 70 Male 3/27/2012 Japan
Primary
Concomitant

Drug Data