Lansoprazole combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 75 Female 2/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 32 Female 132 lb 3/6/2006 United States
Primary
Secondary
Concomitant
Electrocardiogram Qrs Complex Abnormal Other Serious 2/2/2006 58 Male 209 lb 3/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Potassium Increased Life Threatening 2/21/2006 62 Female 223 lb 2/24/2006 United States
Primary
Concomitant
Tremor Hospitalization 5/16/2006 54 Male 7/14/2006 Denmark
Primary
Secondary
Concomitant
Tremor Hospitalization 5/16/2006 54 Male 7/17/2006 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 8/7/2005 64 Male 7/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 9/1/2006 54 Male 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2005 77 Male 161 lb 1/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 5/19/2006 40 Male 203 lb 3/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Retrograde Amnesia Other Serious 12 Male 100 lb 4/13/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Life Threatening 4/3/2005 54 Male 5/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 167 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 9/26/2006 56 Male 7/30/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Required Intervention 60 Male 119 lb 9/11/2007 Physician Japan
Primary
Concomitant
Ulcer Other Serious 75 Female 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2002 75 Female 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Ulcer Other Serious 75 Female 1/28/2008
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 9/3/2007 54 Male 286 lb 3/7/2008 Pharmacist United States
Primary
Concomitant
Overdose Other Serious 3/24/2008 52 Female 3/27/2008 Physician United Kingdom
Primary
Concomitant
Tracheal Haemorrhage Hospitalization 3/27/2008 79 Female 167 lb 4/3/2008 Pharmacist United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 3/27/2008 79 Female 165 lb 6/13/2008 Pharmacist United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 3/27/2008 79 Female 167 lb 10/10/2008 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 10/10/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 8/18/2008 Male 10/20/2008 Other Health Professional Japan
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 5/15/2007 60 Male 119 lb 11/13/2008 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 8/27/2007 85 Male 119 lb 11/20/2008 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 9/3/2007 63 Female 82 lb 11/26/2008 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 8/27/2007 71 Male 165 lb 12/23/2008 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 8/27/2007 71 Male 165 lb 1/9/2009 Physician Japan
Primary
Concomitant
Shock Other Serious 11/23/2008 76 Male 185 lb 1/9/2009 Other Health Professional Canada
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 2/17/2009 34 Male 300 lb 2/18/2009 Pharmacist United States
Primary
Concomitant
Hypotension Life Threatening 3/16/2009 78 Male 5/4/2009 United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 9/16/2009 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 9/16/2009 United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 9/14/2009 Male 11/12/2009 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 11/17/2009 70 Male 12/11/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/17/2009 70 Male 12/21/2009 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 11/27/2007 58 Female 123 lb 2/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/17/2009 70 Male 2/25/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 3/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachypnoea Other Serious 3/4/2010 67 Male 154 lb 3/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 3/9/2010 76 Male 4/27/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 3/9/2010 76 Male 6/9/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 5/11/2010 71 Male 6/24/2010 Physician Japan
Primary
Concomitant
Coagulation Time Prolonged 8/22/2008 60 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2008 68 Male 6/25/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 7/28/2010 Other Health Professional United States
Primary
Concomitant
Interstitial Lung Disease Life Threatening 5/12/2010 71 Male 8/19/2010 Physician Japan
Primary
Concomitant
Wound Secretion Other Serious 1/1/2008 68 Male 8/20/2010 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 8/23/2010 Other Health Professional United States
Primary
Concomitant
Interstitial Lung Disease Life Threatening 5/12/2010 71 Male 9/3/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 22 Female 78 lb 9/13/2010 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/22/2009 22 Female 77 lb 9/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 10/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 10/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2002 75 Female 10/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/31/2010 19 Male 198 lb 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 10/11/2010 United States
Primary
Concomitant
Ulcer Other Serious 1/1/2002 75 Female 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Other Serious 1/1/2002 75 Female 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 10/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 10/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/31/2010 19 Male 198 lb 10/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 10/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/31/2010 19 Male 198 lb 10/9/2010 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/31/2010 10/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Hepatic Failure Other Serious 1/1/2002 75 Female 10/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 139 lb 10/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 10/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 10/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 139 lb 10/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 11/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2002 75 Female 11/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Hepatic Failure Other Serious 1/1/2002 75 Female 11/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 139 lb 11/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 4/28/2010 19 Female 115 lb 11/8/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 11/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 1/1/2002 75 Female 11/5/2010 United Kingdom
Primary
Secondary
Upper Gastrointestinal Haemorrhage Other Serious 4/15/2002 75 Female 11/5/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 1/1/2002 75 Female 138 lb 11/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 11/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 11/22/2010 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 4/15/2002 75 Female 11/15/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 137 lb 12/2/2010 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 12/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 12/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 12/23/2010 United States
Primary
Concomitant
Dyspnoea Other Serious 1/1/2007 65 Male 1/17/2011 United States
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2007 65 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Chills Life Threatening 1/1/2008 70 Male 256 lb 1/31/2011 Lawyer United States
Primary
Secondary
Concomitant
Coagulation Time Prolonged 8/22/2008 60 Female 3/10/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Upper Hospitalization 1/1/2002 75 Female 138 lb 3/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 4/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 4/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 6/22/2009 22 Female 77 lb 4/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Emotional Distress Other Serious 9/18/2002 77 Male 135 lb 5/10/2011 Lawyer United States
Primary
Concomitant
Cerebral Infarction Hospitalization 8/2/2009 62 Male 165 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Anxiety Death 3/27/2001 76 Male 203 lb 5/25/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/25/2007 59 Female 166 lb 5/25/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/2/2005 77 Male 5/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oedema Other Serious 1/1/2007 65 Male 5/27/2011 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2005 77 Male 5/27/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2005 77 Male 161 lb 5/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2005 77 Male 5/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 1/2/2005 77 Male 6/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 1/2/2005 77 Male 6/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 5/1/2007 54 Female 154 lb 6/16/2011 Consumer United States
Primary
Concomitant
Anaphylactic Reaction Life Threatening 5/27/2011 42 Male 134 lb 6/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Injury Death 3/25/2007 59 Female 166 lb 6/24/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/25/2007 59 Female 166 lb 7/6/2011 Consumer United States
Primary
Concomitant
Sepsis Death 7/14/2009 66 Male 139 lb 7/8/2011 Consumer Japan
Primary
Concomitant
Anaphylactic Reaction Hospitalization 6/20/2011 57 Male 7/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Life Threatening 6/20/2011 57 Male 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 6/20/2011 57 Male 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 6/20/2011 57 Male 7/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 6/20/2011 57 Male 7/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Hospitalization 6/20/2011 57 Male 7/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 6/20/2011 57 Male 7/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 38 Male 8/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Bacteriuria Hospitalization 1/1/2011 63 Female 8/31/2011 Other Health Professional France
Primary
Concomitant
Interacting
Renal Artery Stenosis Hospitalization 1/1/2011 63 Female 9/1/2011 Other Health Professional France
Primary
Concomitant
Interacting
Abdominal Pain Upper Hospitalization 1/1/2002 75 Female 138 lb 9/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 38 Male 9/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting

Drug Data