Lansoprazole combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Platelet Count Decreased Life Threatening 10/10/2005 Female 10/18/2005 United States
Primary
Concomitant
Tooth Extraction Other Serious 1/7/2005 58 Female 1/27/2006 Norway
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 1/7/2005 58 Female 4/5/2006 Norway
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 4/3/2006 69 Male 5/2/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Chest Pain Other Serious 4/25/2006 51 Male 135 lb 5/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rash Maculo-papular Required Intervention 9/24/2005 76 Female 159 lb United States
Primary
Concomitant
Tooth Fracture Other Serious 1/7/2005 58 Female 5/17/2006 Norway
Primary
Secondary
Concomitant
Respiratory Arrest Death 4/1/2006 77 Male 5/16/2006 Physician Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 4/25/2006 51 Male 135 lb 5/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tooth Fracture Other Serious 1/7/2005 58 Female 5/23/2006 Norway
Primary
Secondary
Concomitant
Respiratory Rate Increased Death 4/1/2006 77 Male 6/19/2006 Physician Japan
Primary
Secondary
Concomitant
Tracheal Disorder Death 4/1/2006 77 Male 7/5/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 9/19/2006 90 Male 10/11/2006 United States
Primary
Concomitant
Visual Acuity Reduced Disability 8/1/2006 49 Female 82 lb 10/24/2006 Physician Japan
Primary
Secondary
Concomitant
Death Death 12/16/2006 Male 167 lb 12/29/2006 Canada
Primary
Concomitant
Rectal Haemorrhage Required Intervention 7/12/2006 40 Female 7/16/2006 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Required Intervention 8/15/2006 Female 160 lb 8/23/2006 Pharmacist United States
Primary
Concomitant
Occult Blood Positive Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Haemorrhage Required Intervention 8/16/2006 78 Female 150 lb 10/2/2006 United States
Primary
Concomitant
Subclavian Vein Thrombosis Life Threatening 10/17/2006 43 Female 155 lb 10/22/2006 United States
Primary
Concomitant
Respiratory Rate Decreased 10/19/2006 40 Female 295 lb 10/20/2006 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 4/14/2006 Male 228 lb 1/18/2007 Physician United States
Primary
Secondary
Renal Cell Carcinoma Stage Unspecified Death 12/16/2006 Male 167 lb 2/21/2007 Canada
Primary
Concomitant
Renal Failure Acute Other Serious 11/10/2006 60 Female 146 lb 2/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 3/8/2007 11 Female 53 lb 3/30/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 10/7/2006 79 Female 4/25/2007 Physician Ireland
Primary
Concomitant
Neutropenia Hospitalization 2/16/2007 76 Female 4/26/2007 Other Health Professional France
Primary
Secondary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 5/30/2007 Female 31 lb 6/28/2007 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 5/23/2007 Male 110 lb 7/18/2007 Physician Japan
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 9/26/2006 56 Male 7/30/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/23/2007 Male 110 lb 8/6/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2003 60 Male 428 lb 8/9/2007 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 7/5/2007 74 Male 106 lb 8/17/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 56 Female 8/24/2007
Primary
Secondary
Thrombosis Required Intervention 6/17/2007 35 Male 88 lb 6/20/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 6/8/2007 Male 107 lb 6/11/2007 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 60 Male 119 lb 9/11/2007 Physician Japan
Primary
Concomitant
Pancreatitis Other Serious 5/30/2007 Female 31 lb 9/17/2007 Pharmacist
Primary
Concomitant
Sepsis Life Threatening 7/26/2007 69 Male 198 lb 9/19/2007 Physician Germany
Primary
Secondary
Concomitant
Infection Life Threatening 7/8/2007 19 Male 164 lb 10/4/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 12/1/2005 77 Female 11/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 4/30/2007 76 Female 119 lb 12/6/2007 Physician Japan
Primary
Secondary
Concomitant
Chest Pain 9/19/2007 Female 190 lb 12/14/2007 United States
Primary
Concomitant
Transplant Failure Hospitalization 12/13/2007 53 Male 225 lb 12/13/2007 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 11/6/2007 Female 115 lb 11/15/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Required Intervention 11/14/2007 70 Female 146 lb 12/3/2007 Pharmacist United States
Primary
Concomitant
Sepsis Life Threatening 7/26/2007 69 Male 198 lb 1/2/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/26/2007 69 Male 198 lb 1/8/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pancreatitis Life Threatening 11/29/2007 63 Male 238 lb 2/6/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 11/21/2006 2/14/2008 Physician Canada
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 4/30/2007 76 Female 119 lb 2/14/2008 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 4/30/2007 76 Female 119 lb 3/17/2008 Physician Japan
Primary
Secondary
Concomitant
Mental Status Changes Required Intervention 2/17/2008 80 Female 141 lb 2/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 9/3/2007 54 Male 286 lb 3/7/2008 Pharmacist United States
Primary
Concomitant
Stomatitis Other Serious 2/20/2007 63 Male 3/31/2008 Physician Japan
Primary
Concomitant
Death Death 4/2/2007 Male 4/23/2008 Physician Denmark
Primary
Secondary
Concomitant
Injection Site Warmth 4/27/2008 Female 137 lb 6/13/2008 Consumer United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 3/27/2008 79 Female 165 lb 6/13/2008 Pharmacist United States
Primary
Concomitant
Skin Exfoliation Life Threatening 3/9/2008 Female 143 lb 3/18/2008 Pharmacist United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/12/2008 59 Male 6/17/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pain Hospitalization 11/15/2006 51 Male 88 lb 7/8/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 5/1/2007 Female 7/28/2008 Physician Canada
Primary
Secondary
Concomitant
Sepsis Death 22 Male 8/28/2008 Pharmacist United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/12/2008 Male 135 lb 9/9/2008 Japan
Primary
Secondary
Concomitant
Memory Impairment Hospitalization 68 Female 9/12/2008 Consumer Australia
Primary
Concomitant
Leukopenia Death 9/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Hospitalization 3/27/2008 79 Female 167 lb 10/10/2008 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/30/2003 67 Female 298 lb 2/21/2007 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Required Intervention 5/15/2007 60 Male 119 lb 11/13/2008 Physician Japan
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 7/2/2008 62 Male 183 lb 7/17/2008 Pharmacist United States
Primary
Concomitant
Blood Potassium Increased Life Threatening 6/24/2008 Male 167 lb 7/2/2008 United States
Primary
Concomitant
Blood Creatinine Increased Required Intervention 5/31/2008 51 Male 150 lb 6/24/2008 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 5/10/2008 86 Male 12/11/2008 Pharmacist Ireland
Primary
Secondary
Concomitant
Gastritis Hospitalization 61 Female 12/9/2008 United States
Primary
Secondary
Concomitant
Tooth Loss Disability 10/1/2008 78 Female 12/29/2008 Other Health Professional Switzerland
Primary
Concomitant
Intestinal Obstruction Hospitalization 8/13/2007 Male 1/6/2009 United Kingdom
Primary
Secondary
Concomitant
Angina Unstable Other Serious 7/9/2001 Male 194 lb 1/8/2009 Physician United States
Primary
Concomitant
Angina Unstable Other Serious 7/9/2001 Male 194 lb 1/24/2009 Physician United States
Primary
Concomitant
Oropharyngeal Pain Other Serious 81 Female 1/29/2009 Consumer United Kingdom
Primary
Secondary
Myocardial Infarction Life Threatening 1/18/2009 65 Male 223 lb 2/9/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 Male 194 lb 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Pseudomonal Other Serious 1/1/1991 45 Female 270 lb 2/12/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 Male 194 lb 2/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 1/24/2009 66 Male 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 12/16/2008 79 Male 2/23/2009 Physician United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Death 1/24/2009 66 Male 3/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Injury Hospitalization 1/1/2009 Female 4/3/2009 Consumer United Kingdom
Primary
Secondary
Right Ventricular Failure Hospitalization 3/10/2009 62 Female 66 lb 4/21/2009 United Kingdom
Primary
Concomitant
Right Ventricular Failure Hospitalization 3/10/2009 62 Female 66 lb 4/21/2009 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 Male 194 lb 4/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 3/10/2009 62 Female 66 lb 4/24/2009 United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 3/24/2003 45 Female 138 lb 5/18/2009 United States
Primary
Concomitant
Joint Swelling Disability 4/23/2009 63 Female 5/26/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/22/2009 69 Female 6/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophil Count Abnormal Other Serious 7/8/2007 19 Male 164 lb 6/17/2009 Physician United States
Primary
Secondary
Concomitant
Streptococcal Infection Other Serious 7/8/2007 19 Male 164 lb 6/30/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/11/2005 58 Female 171 lb 7/21/2009 United States
Primary
Concomitant
Chest Pain Hospitalization 4/25/2006 51 7/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 5/24/2009 Male 150 lb 9/1/2009 Physician United Kingdom
Primary
Concomitant
Road Traffic Accident Hospitalization 2/23/2001 59 Male 190 lb 9/23/2009 Other Health Professional United States
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 6/10/2009 74 Female 131 lb 6/10/2009 Pharmacist United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Tenderness Other Serious 8/9/2009 65 Female 154 lb 10/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Death 3/7/2008 74 Female 10/8/2009 United Kingdom
Primary
Concomitant
Platelet Count Decreased Required Intervention 9/5/2009 88 Female 163 lb 9/14/2009 Pharmacist United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 9/23/2009 75 Male 209 lb 9/25/2009 Pharmacist United States
Primary
Concomitant
Wound Infection Staphylococcal Required Intervention 9/15/2009 17 Male 161 lb 10/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 9/8/2009 53 Female 11/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Thinking Abnormal Other Serious 9/27/2009 67 Male 203 lb 11/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Personality Change Other Serious 9/27/2009 67 Male 203 lb 11/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Thinking Abnormal Other Serious 9/27/2009 67 Male 203 lb 11/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cerebral Infarction Death 10/5/2009 83 Female 11/25/2009 Physician Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 3/9/2009 Male 154 lb 11/25/2009 United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 9/6/2009 11/3/2009 United Kingdom
Primary
Concomitant
Thinking Abnormal Other Serious 9/27/2009 67 Male 11/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Other Serious 8/24/2007 Female 157 lb 12/17/2009 Pharmacist United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 10/22/2009 65 Male 116 lb 11/17/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 1/22/2009 69 Female 12/18/2009 United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 11/24/2009 57 Female 12/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cerebral Infarction Death 10/5/2009 83 Female 1/7/2010 Physician Canada
Primary
Concomitant
Respiratory Failure Other Serious 11/14/2009 56 Female 136 lb 1/21/2010 United States
Primary
Secondary
Concomitant
Cerebral Infarction Death 10/5/2009 83 Female 2/17/2010 Physician Canada
Primary
Concomitant
Weight Decreased Other Serious 5/1/2000 Female 151 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 2/23/2010 Other Health Professional United States
Primary
Concomitant
Vith Nerve Paralysis Required Intervention 9/15/2009 17 Male 161 lb 2/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 3/8/2010 Other Health Professional United States
Primary
Concomitant
Vith Nerve Paralysis Required Intervention 9/15/2009 17 Male 161 lb 3/5/2010 Physician United States
Primary
Secondary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 3/18/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2000 Female 151 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Ideation Disability 11/18/2009 38 Female 3/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Other Serious 3/14/2010 75 Male 4/2/2010 Physician Switzerland
Primary
Concomitant
Vith Nerve Paralysis Required Intervention 9/15/2009 17 Male 161 lb 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Required Intervention 12/13/2009 76 Female 130 lb 12/14/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2000 35 Female 151 lb 4/15/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2000 35 Female 151 lb 4/26/2010 United States
Primary
Secondary
Concomitant
Hypotension Other Serious 85 Female 4/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Prostate Cancer Death Male 5/4/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2000 35 Female 151 lb 5/5/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2000 35 Female 151 lb 5/7/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2000 35 Female 151 lb 5/11/2010 United States
Primary
Secondary
Concomitant
Tooth Infection Other Serious 3/4/1996 25 Female 5/27/2010 Pharmacist United States
Primary
Secondary
Concomitant

Drug Data