Lansoprazole combined with Metronidazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 198 lb 2/8/2006
Primary
Concomitant
Osteoarthritis Other Serious 2/5/2003 62 Male 251 lb 2/16/2006 Physician United States
Primary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 2/10/2006 United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 80 Female 2/21/2006 Physician United States
Primary
Concomitant
Sinus Bradycardia Other Serious 1/1/2004 68 Female 2/3/2006 Physician United States
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 2/5/2003 62 Male 251 lb 2/24/2006 Physician United States
Primary
Concomitant
Serotonin Syndrome Other Serious 45 Male 3/27/2006 United States
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 1/8/2005 69 Female 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 45 Male 4/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Mesenteric Vein Thrombosis Life Threatening 12/28/2005 Female 94 lb United States
Primary
Concomitant
Vision Blurred Other Serious 11/18/2005 59 Female 5/15/2006 Physician Norway
Primary
Concomitant
Osteoarthritis Other Serious 2/5/2003 62 Male 251 lb 5/16/2006 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 11/18/2005 59 Female 5/22/2006 Physician Norway
Primary
Concomitant
Vomiting Other Serious 11/30/2005 68 Male 5/12/2006 Physician Japan
Primary
Concomitant
Nausea Hospitalization 5/8/2006 45 Female 104 lb 5/25/2006
Primary
Secondary
Concomitant
Gastritis Other Serious 5/8/2006 45 Female 104 lb 5/30/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 65 Female 5/30/2006 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 65 Female 6/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 65 Female 6/14/2006
Primary
Secondary
Concomitant
Weight Decreased Other Serious 65 Female 6/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 65 Female 6/12/2006 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 65 Female 6/15/2006 United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 43 Female 7/5/2006
Primary
Secondary
Concomitant
Rash Disability 43 Female 7/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 43 Female 7/7/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 65 Female 7/14/2006 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 65 Female 7/17/2006 United Kingdom
Primary
Concomitant
Tachycardia Death 8/7/2006 18 Male 109 lb 8/7/2006 Pharmacist United States
Primary
Concomitant
Urticaria Required Intervention 1/14/2006 Male 163 lb 9/8/2006 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 65 Female 10/12/2006 United Kingdom
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Tachycardia Required Intervention 8/1/2006 Male 8/7/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Required Intervention 7/23/2006 68 Female 148 lb 7/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 25 Male 1/19/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Psychiatric Symptom Other Serious 62 Male 198 lb 1/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria Hospitalization 12/4/2006 Male 2/2/2007 Consumer Germany
Primary
Secondary
Concomitant
Urticaria Hospitalization 12/4/2006 Male 2/16/2007 Physician Germany
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 25 Male 2/14/2007 United Kingdom
Primary
Secondary
Sepsis Other Serious 9/1/2006 73 Male 2/26/2007 Physician Ireland
Primary
Concomitant
Interacting
Swollen Tongue Other Serious 25 Male 2/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Purpura Life Threatening 10/19/2006 72 Male 3/23/2007
Primary
Concomitant
Myocardial Infarction Death 2/24/2007 61 Female 148 lb 3/22/2007 United Kingdom
Primary
Concomitant
Swollen Tongue Other Serious 25 Male 3/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Meningitis Aseptic Other Serious 7/1/2004 42 Male 3/30/2007 United Kingdom
Primary
Concomitant
Meningitis Aseptic Other Serious 42 Male 3/26/2007 United Kingdom
Primary
Concomitant
Sinus Tachycardia Other Serious 3/8/2007 11 Female 53 lb 3/30/2007 Physician United States
Primary
Concomitant
Meningitis Aseptic Hospitalization 7/1/2004 42 Male 4/12/2007 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Meningitis Aseptic Hospitalization 7/1/2004 42 Male 5/2/2007 Physician United Kingdom
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Anaemia Haemolytic Autoimmune Other Serious 5/17/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/4/2007 55 Male 189 lb 5/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Meningitis Aseptic Other Serious 7/1/2004 42 Male 6/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Vein Disorder Death 4/16/2007 65 Female 154 lb 6/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Troponin I Increased Other Serious 2/25/2007 61 Female 148 lb 6/8/2007 Pharmacist United Kingdom
Primary
Concomitant
Septic Shock Other Serious 2/25/2007 61 Female 148 lb 6/21/2007 Pharmacist United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 7/3/2007 60 Male 254 lb 7/24/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/30/2007 Female 153 lb 8/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 7/3/2007 60 Male 254 lb 8/9/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2003 60 Male 428 lb 8/9/2007 Pharmacist United States
Primary
Concomitant
Disease Progression Death 8/9/2007 66 Female 153 lb 8/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Hospitalization 4/19/2007 Female 165 lb 4/24/2007 Pharmacist United States
Primary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Acute Death 9/4/2007 84 Female 121 lb 10/1/2007
Primary
Concomitant
Toxic Epidermal Necrolysis 6/18/2007 61 Male 10/19/2007 Other Health Professional Ireland
Primary
Secondary
Concomitant
Respiratory Failure Required Intervention 7/10/2007 69 Male 7/13/2007 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/18/2007 10/22/2007 Consumer Ireland
Primary
Secondary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 4/17/2007 Female 185 lb 10/26/2007 United States
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/23/2007 Male 139 lb 11/7/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/23/2007 Male 139 lb 11/28/2007 United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 10/25/2007 12/6/2007 Consumer United Kingdom
Primary
Concomitant
Meningitis Aseptic Hospitalization 42 Male 12/18/2007 United Kingdom
Primary
Concomitant
Somnolence Other Serious 8/15/2007 53 Male 1/24/2008 Consumer United Kingdom
Primary
Concomitant
Meningitis Aseptic Hospitalization 7/1/2004 42 Male 3/12/2008 United Kingdom
Primary
Concomitant
Musculoskeletal Stiffness Hospitalization 7/1/2004 42 Male 3/12/2008 Physician United Kingdom
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 16 Male 4/12/2008 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Required Intervention 16 Male 108 lb 4/16/2008 Consumer United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 16 Male 108 lb 4/23/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Death 2/24/2007 61 Female 148 lb 5/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 16 Male 6/2/2008 Pharmacist United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 16 Male 6/2/2008 United States
Primary
Concomitant
Petechiae Required Intervention 3/24/2008 85 Female 137 lb 3/26/2008 Pharmacist United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 4/22/2008 82 Female 172 lb 5/2/2008 United States
Primary
Concomitant
Platelet Count Decreased Required Intervention 4/15/2008 54 Male 5/5/2008 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 33 Male 8/13/2008 Italy
Primary
Secondary
Concomitant
Disseminated Tuberculosis Other Serious 6/1/2008 41 Female 8/28/2008 Physician Slovenia
Primary
Concomitant
Sepsis Death 22 Male 8/28/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 33 Male 9/4/2008 Consumer Italy
Primary
Secondary
Rash Maculo-papular Hospitalization 7/26/2008 9/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 33 Male 9/5/2008 Italy
Primary
Secondary
Accidental Exposure 7/10/2008 Female 150 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Nodule 7/24/2008 Female 145 lb 9/12/2008 United States
Primary
Concomitant
Leukopenia Death 9/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 7/14/2008 Female 26 lb 9/17/2008 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Hospitalization 9/15/2008 Female 143 lb 10/1/2008 Physician United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 4/29/2007 Male 10/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 10/2/2005 51 Female 10/10/2008 United Kingdom
Primary
Concomitant
Nausea Hospitalization 67 Male 10/27/2008 Other Health Professional Japan
Primary
Concomitant
Enterocolitis Haemorrhagic Hospitalization 1/31/2008 67 Male 11/5/2008 Japan
Primary
Secondary
Blood Potassium Increased Life Threatening 6/24/2008 Male 167 lb 7/2/2008 United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 10/1/2008 44 Female 10/24/2008 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Required Intervention 8/21/2008 44 Female 150 lb 10/1/2008 United States
Primary
Secondary
Concomitant
Platelet Count Increased Required Intervention 8/30/2008 66 Female 287 lb 10/3/2008 Pharmacist United States
Primary
Concomitant
Pulse Absent Required Intervention 7/31/2008 77 Male 148 lb 8/12/2008 Pharmacist United States
Primary
Concomitant
Dyspnoea Hospitalization 71 Female 11/24/2008 Pharmacist United Kingdom
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 11/13/2008 Male 12/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 11/13/2008 Male 12/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Meningitis Aseptic Hospitalization 7/1/2004 42 Male 1/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Death 36 Female 3/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Death 36 Female 3/26/2009 United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 1/27/2009 Female 185 lb 4/1/2009 Physician Ireland
Primary
Concomitant
Vomiting Other Serious 4/29/2007 Male 4/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Poisoning Death 36 Female 4/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 36 Female 4/2/2009 United States
Primary
Secondary
Convulsion 2/8/2009 Female 2/12/2009 Pharmacist United States
Primary
Concomitant
Feeling Cold Required Intervention 2/6/2009 46 Male 190 lb 3/18/2009 Pharmacist United States
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 3/31/2009 Female 5/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 9/1/2006 73 6/17/2009 Other Health Professional Ireland
Primary
Concomitant
Interacting
Sepsis Other Serious 9/1/2006 73 6/18/2009 Other Health Professional Ireland
Primary
Concomitant
Interacting
Peritonitis Hospitalization 11/1/2004 Male 141 lb 6/23/2009 Physician Turkey
Primary
Secondary
Concomitant
Sepsis Other Serious 8/4/2004 Male 132 lb 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Required Intervention 3/26/2009 49 Male 170 lb 5/8/2009 Pharmacist United States
Primary
Concomitant
Postoperative Thrombosis Required Intervention 4/7/2009 47 Male 218 lb 4/10/2009 Pharmacist United States
Primary
Concomitant
Depressed Level Of Consciousness Required Intervention 4/16/2009 49 Female 130 lb 4/17/2009 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Required Intervention 5/12/2009 81 Female 125 lb 5/13/2009 United States
Primary
Concomitant
No Adverse Event Other Serious 8/4/2004 65 Male 7/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypoxia Hospitalization 7/16/2009 74 Female 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 86 Female 8/26/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 86 Female 8/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Death 86 Female 8/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Other Serious 86 Female 8/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Dysuria Other Serious 8/27/2009 Male 158 lb 9/4/2009 Canada
Primary
Concomitant
Wrong Technique In Drug Usage Process 4/18/2008 Male 117 lb 9/12/2009 Consumer United States
Primary
Concomitant
Accidental Needle Stick 7/10/2008 Female 150 lb 9/12/2009 United States
Primary
Concomitant
Injection Site Nodule 7/24/2008 Female 145 lb 9/12/2009 United States
Primary
Concomitant
Pyrexia Required Intervention 6/21/2009 55 Male 202 lb 7/14/2009 Pharmacist United States
Primary
Concomitant
Pulmonary Haemorrhage Life Threatening 3/25/2009 Female 9/28/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Oral Other Serious 2/9/2009 Female 136 lb 10/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Haemorrhage Life Threatening 3/25/2009 Female 10/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Life Threatening 3/25/2009 Female 10/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant

Drug Data