Lansoprazole combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatitis Hospitalization 2/9/2005 69 Male 4/4/2005 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 11/3/2005 61 Female 1/18/2006 Consumer Singapore
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/1999 59 Female 161 lb 1/19/2006 Physician United States
Primary
Concomitant
Vomiting Death 3/1/2005 88 Male 176 lb 1/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Disorder Hospitalization 1/1/2000 64 Male 227 lb 1/20/2006 Physician United States
Primary
Concomitant
Skin Discolouration Required Intervention 8/23/2005 Female 9/2/2005 United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 8/22/2005 Male 8/31/2005 United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 10/10/2005 Female 10/18/2005 United States
Primary
Concomitant
Pulmonary Hypertension Death 10/19/2005 Male 1/31/2006 United States
Primary
Concomitant
Breast Cancer Other Serious 11/3/2005 61 Female 2/9/2006 Consumer Singapore
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/27/2005 72 Female 161 lb 2/14/2006 Consumer United States
Primary
Concomitant
Sleep Disorder Hospitalization 1/1/2000 64 Male 227 lb 2/27/2006 Physician United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 12/1/2003 Male 146 lb 2/27/2006 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 10/12/2005 Female 2/28/2006 Physician United States
Primary
Secondary
Concomitant
Intestinal Haemorrhage Other Serious 1/1/2002 89 Female 120 lb 12/29/2005 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2003 62 Female 209 lb 3/28/2006 Lawyer Australia
Primary
Concomitant
Staphylococcal Infection Hospitalization 49 Male 3/20/2006 United States
Primary
Secondary
Concomitant
Hallucination Other Serious 62 Female 3/31/2006 Pharmacist United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/2001 62 Female 209 lb 4/3/2006 Lawyer Australia
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/2001 62 Female 209 lb 4/4/2006 Physician Australia
Primary
Concomitant
Pancreatitis Hospitalization 10/1/2005 31 Male 11/4/2005 Physician United States
Primary
Concomitant
Hallucination Other Serious 62 Female 4/14/2006 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 8/1/2004 78 Male 4/21/2006 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Death 11/28/2005 69 Male 5/12/2006 France
Primary
Secondary
Concomitant
Rhabdomyolysis Required Intervention 3/7/2006 57 Male 320 lb 3/23/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/16/2006 63 Male 164 lb 5/25/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/2/2006 66 198 lb 7/11/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2006 Male 7/19/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 11/25/2005 Female 326 lb 7/28/2006 Physician United States
Primary
Concomitant
Rectal Haemorrhage Life Threatening 8/20/2006 85 Male 141 lb 9/8/2006 United Kingdom
Primary
Secondary
Concomitant
Occult Blood Positive Required Intervention 1/14/2006 74 Female 109 lb 6/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/20/2006 85 Male 141 lb 10/10/2006 United Kingdom
Primary
Secondary
Concomitant
Pemphigoid Other Serious 70 Male 10/23/2006 United States
Primary
Concomitant
Stress Other Serious 11/1/2003 Female 187 lb 11/22/2006 Physician United States
Primary
Concomitant
Electrocardiogram T Wave Inversion Hospitalization 9/25/2007 Female 10/18/2007 Physician Italy
Primary
Concomitant
Somnolence Required Intervention 9/12/2007 51 Male 179 lb 10/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Medication Error Death 9/5/2006 78 Female 201 lb 11/21/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Lethargy Required Intervention 10/24/2007 93 Male 179 lb 10/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Loss Of Consciousness Death 11/16/2007 48 Male 331 lb 11/26/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Required Intervention 11/14/2007 70 Female 146 lb 12/3/2007 Pharmacist United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 4/22/2008 82 Female 172 lb 5/2/2008 United States
Primary
Concomitant
Platelet Count Decreased Required Intervention 4/15/2008 54 Male 5/5/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 3/19/2008 3/26/2008 Pharmacist United States
Primary
Concomitant
Heart Rate Decreased Life Threatening 4/22/2008 Male 111 lb 4/24/2008 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 41 8/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 22 Male 8/28/2008 Pharmacist United States
Primary
Concomitant
Lethargy Hospitalization 10/20/2008 48 Female 10/20/2008 Pharmacist United States
Primary
Concomitant
Thrombosis Hospitalization 35 Female 11/20/2008 United States
Primary
Secondary
Thrombosis Hospitalization 35 Female 183 lb 12/11/2008 United States
Primary
Secondary
Platelet Count Decreased Death 3/18/2008 Male 190 lb 12/24/2008 Other Health Professional Turkey
Primary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Pyrexia Other Serious 53 Female 2/10/2009 Other Health Professional United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 78 Female 3/26/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Required Intervention 10/16/2008 69 Male 226 lb 1/12/2009 Pharmacist United States
Primary
Concomitant
Mental Status Changes Required Intervention 2/24/2009 80 Male 207 lb 2/24/2009 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 2/6/2009 75 Male 3/4/2009 Pharmacist United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 3/24/2009 49 Male 278 lb 3/30/2009 Pharmacist United States
Primary
Concomitant
Serotonin Syndrome 3/1/2009 55 Female 156 lb 3/30/2009 Pharmacist United States
Primary
Concomitant
Lethargy Required Intervention 2/17/2009 45 Female 138 lb 2/17/2009 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Required Intervention 3/24/2009 50 Female 198 lb 3/25/2009 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 3/24/2003 45 Female 138 lb 5/18/2009 United States
Primary
Concomitant
Cerebral Haemorrhage Required Intervention 4/13/2009 Male 193 lb 4/14/2009 Pharmacist United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 4/24/2009 89 Female 151 lb 4/27/2009 Pharmacist United States
Primary
Concomitant
Respiratory Distress Hospitalization 4/20/2009 59 Male 196 lb 4/22/2009 Pharmacist United States
Primary
Concomitant
Pain In Extremity Hospitalization 54 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Peripheral Ischaemia Hospitalization 6/23/2009 Female 168 lb 8/11/2009 United Kingdom
Primary
Concomitant
Flushing 7/1/2008 Male 8/21/2009 United States
Primary
Concomitant
Flushing 8/18/2008 Male 8/21/2009 United States
Primary
Concomitant
Palpitations 7/1/2008 55 Male 165 lb 8/21/2009 Consumer United States
Primary
Concomitant
Paraesthesia Male 8/22/2009 United States
Primary
Concomitant
Flushing Male 8/22/2009 United States
Primary
Concomitant
Troponin Increased Hospitalization 54 Female 8/26/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 8/15/2002 54 Male 205 lb 9/3/2009 United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 5/15/2009 76 Female 192 lb 5/29/2009 Pharmacist United States
Primary
Concomitant
Vomiting Required Intervention 11/4/2008 39 Male 11/6/2008 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/20/2009 67 Female 135 lb 7/17/2009 Pharmacist United States
Primary
Concomitant
Confusional State Required Intervention 11/17/2008 82 Female 134 lb 11/19/2008 Pharmacist United States
Primary
Secondary
Concomitant
Hepatitis Cholestatic Hospitalization 6/1/2009 72 Female 9/28/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/17/2007 68 Male 9/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7 Female 10/17/2009 Other Health Professional United States
Primary
Concomitant
Mental Status Changes Required Intervention 8/29/2009 53 Female 115 lb 8/31/2009 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/30/2009 Male 187 lb 9/11/2009 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased Life Threatening 9/23/2009 75 Male 209 lb 9/25/2009 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 54 Female 10/22/2009 United States
Primary
Concomitant
Pemphigoid Other Serious 11/12/2009 Physician United States
Primary
Secondary
Jaundice Hospitalization 7/27/2009 Female 143 lb 11/25/2009 Physician Italy
Primary
Concomitant
Jaundice Cholestatic Other Serious 78 Female 12/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/11/2008 57 Female 165 lb 12/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Jaundice Cholestatic Other Serious 78 Female 1/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Life Threatening 8/15/2005 75 Male 1/20/2010 Consumer United Kingdom
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 12/23/2008 78 Female 1/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Oral Hospitalization 57 Male 1/26/2010 Norway
Primary
Concomitant
Treatment Noncompliance Death Male 3/11/2010 Pharmacist Canada
Primary
Concomitant
Treatment Noncompliance Death Male 3/11/2010 Pharmacist Canada
Primary
Concomitant
Sensory Disturbance Other Serious 10/7/2008 Male 205 lb 3/25/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/1/2008 Female 176 lb 3/29/2010 Consumer Netherlands
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/12/2010 46 Female 124 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Post Procedural Stroke Hospitalization 5/20/2009 65 Male 130 lb 4/28/2010 Pharmacist United States
Primary
Concomitant
Dysphagia Other Serious Male 5/3/2010 Other Health Professional United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 12/27/2008 54 Male 216 lb 5/28/2010 Physician Canada
Primary
Secondary
Concomitant
Osteopenia Other Serious 2/1/2010 47 Female 128 lb 5/28/2010 Other Health Professional United States
Primary
Concomitant
Osteopenia Other Serious 2/1/2010 47 Female 128 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Lung Cancer Metastatic Death 3/28/2007 66 Female 7/15/2010 Lawyer United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 65 Male 7/21/2010 Pharmacist Canada
Primary
Concomitant
Interacting
Thrombocytopenia Other Serious 6/1/2010 71 Male 8/2/2010 Physician United States
Primary
Concomitant
Idiopathic Pulmonary Fibrosis Other Serious 10/4/2007 58 Male 266 lb 8/2/2010 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 6/26/2010 58 Female 8/4/2010 Physician France
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 7/28/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 8/23/2010 Other Health Professional United States
Primary
Concomitant
Urine Flow Decreased 8/28/2009 75 Male 210 lb 8/27/2010 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 150 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 150 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Eyelid Oedema Other Serious 78 Female 10/25/2010 Pharmacist Canada
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 65 Male 10/28/2010 Other Health Professional France
Primary
Concomitant
Interacting
Vision Blurred Other Serious 9/1/2010 78 Female 236 lb 11/23/2010 Pharmacist Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2009 65 Female 11/24/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Disease Progression Death Male 12/7/2010 Physician Canada
Primary
Concomitant
Pancreatic Carcinoma Other Serious 12/14/2010 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/15/2008 60 Male 12/15/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 3/12/2010 46 Female 124 lb 12/16/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 66 Female 243 lb 11/29/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 9/1/2010 78 Female 236 lb 12/30/2010 Pharmacist Canada
Primary
Concomitant
Blood Pressure Increased 65 Male 1/3/2011 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 1/1/2007 65 Male 1/17/2011 United States
Primary
Concomitant
Cardiomyopathy Other Serious Male 1/25/2011 Physician Canada
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 6/21/2010 63 Female 101 lb 1/26/2011 Physician Italy
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/1/2007 65 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Sinus Congestion 2/1/2010 60 Female 192 lb 1/28/2011 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 1/18/2011 81 Female 138 lb 1/31/2011 Physician United Kingdom
Primary
Concomitant
Wrong Drug Administered Other Serious 6/21/2010 63 Female 101 lb 2/21/2011 Physician Italy
Primary
Secondary
Concomitant
Dry Mouth 1/1/2010 80 Male 3/8/2011 Consumer United States
Primary
Concomitant
Gastrooesophageal Reflux Disease 1/26/2011 64 Female 3/10/2011 Consumer United States
Primary
Concomitant
Electrocardiogram St-t Segment Elevation Death 36 Male 3/15/2011 Physician United States
Primary
Concomitant
Interacting
Syncope Other Serious 36 Male 3/21/2011 Physician United States
Primary
Concomitant
Interacting
Insomnia Death 36 Male 3/21/2011 Physician United States
Primary
Concomitant
Interacting
Syncope Other Serious 36 Male 4/1/2011 Physician United States
Primary
Concomitant
Interacting
Drug Interaction Death 36 Male 4/5/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Convulsion Death 36 Male 4/19/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Muscular Weakness 1/1/2011 75 Female 4/21/2011 Consumer United States
Primary
Concomitant
Drug Interaction Other Serious 36 Male 4/26/2011 Physician United States
Primary
Concomitant
Interacting
Malaise Other Serious 1/1/2010 50 Female 165 lb 4/26/2011 Consumer United States
Primary
Concomitant
Anxiety Death 3/27/2001 76 Male 203 lb 5/25/2011 Other Health Professional United States
Primary
Concomitant
Electrocardiogram St Segment Elevation Death 36 Male 7/14/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Excoriation Other Serious 36 Male 7/14/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Interaction Death 36 Male 7/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting

Drug Data