Lansoprazole combined with Lorazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Personality Change Other Serious 10/6/2005 Female 141 lb 1/18/2006 Pharmacist Ireland
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/11/2005 Female 1/18/2006 United Kingdom
Primary
Concomitant
Verbal Abuse Other Serious 10/6/2005 Female 141 lb 1/19/2006 Pharmacist Ireland
Primary
Concomitant
Cardiac Arrest Death 1/3/2006 64 Female 1/19/2006 United States
Primary
Concomitant
Sudden Death Death 12/22/2005 53 Male 1/12/2006 Physician Ireland
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/5/2001 34 Male 2/8/2006 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 6/1/2003 58 Female 141 lb 2/24/2006 Lawyer Canada
Primary
Concomitant
Myocardial Infarction Death 4/1/2005 64 Male 3/7/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Pruritus Generalised Other Serious 12/1/2005 37 Female 160 lb 3/8/2006 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 4/1/2005 64 Male 3/10/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Contusion Hospitalization 3/17/2004 53 Female 190 lb 12/27/2005 Consumer United States
Primary
Concomitant
Pruritus Generalised Other Serious 12/1/2005 37 Female 160 lb 4/5/2006 Consumer United States
Primary
Secondary
Concomitant
Stomach Discomfort Hospitalization 6/1/2003 58 Female 141 lb 4/7/2006 Physician Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
Restless Legs Syndrome Hospitalization 11/11/2005 70 Female 4/27/2006 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2001 55 Male 5/9/2006 Other Health Professional United States
Primary
Concomitant
Injection Site Haemorrhage Required Intervention 9/23/2005 42 Female 183 lb 2/28/2006 United States
Primary
Secondary
Concomitant
Superior Sagittal Sinus Thrombosis Other Serious 3/1/2006 33 Female 132 lb 5/25/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 12/22/2004 57 Male 210 lb 5/26/2006 Consumer Canada
Primary
Concomitant
Death Death 1/1/2006 55 Female 6/14/2006 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Death 5/30/2006 55 Female 7/6/2006 United States
Primary
Concomitant
Drug Dependence Other Serious 7/3/2006 Female 7/12/2006 United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 4/2/2006 72 Female 7/14/2006 Other Health Professional France
Primary
Secondary
Tumour Invasion Death 12/22/2005 53 Male 8/4/2006 Physician Ireland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2006 44 Female 8/4/2006 Pharmacist Canada
Primary
Concomitant
Leukopenia Other Serious 5/1/2006 44 Female 8/9/2006 Pharmacist Canada
Primary
Concomitant
Urinary Retention Hospitalization 4/2/2006 72 Female 8/10/2006 Other Health Professional France
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Death 4/13/2006 42 Female 95 lb 8/9/2006 Physician Japan
Primary
Concomitant
Granulocytopenia Required Intervention 1/15/2006 43 Female 202 lb 4/17/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 6/4/2006 59 Male 7/21/2006 Pharmacist United States
Primary
Concomitant
Superior Sagittal Sinus Thrombosis Other Serious 3/1/2006 33 Female 132 lb 9/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Death 4/13/2006 42 Female 95 lb 9/6/2006 Physician Japan
Primary
Concomitant
Pupil Fixed Required Intervention 6/21/2006 Male 157 lb 6/22/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Death 9/18/2006 53 Male 10/9/2006 Physician Japan
Primary
Secondary
Concomitant
Lipase Increased Other Serious 4/1/2006 68 Female 10/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 9/18/2006 52 Male 10/17/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 9/18/2006 52 Male 10/17/2006 Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 39 Male 10/19/2006 Other Health Professional France
Primary
Secondary
Concomitant
Surgery Other Serious 72 Female 11/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypogammaglobulinaemia Other Serious 4/18/2005 59 Female 11/17/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 11/15/2006 62 Male 12/8/2006 Physician United Kingdom
Primary
Concomitant
Rash Hospitalization 11/15/2006 62 Male 12/22/2006 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Tendonitis Hospitalization 7/8/2005 36 Male 153 lb 3/13/2006 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Lipase Increased Other Serious 4/1/2006 68 Female 1/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Required Intervention 8/15/2006 Female 160 lb 8/23/2006 Pharmacist United States
Primary
Concomitant
Occult Blood Positive Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 12/13/2005 43 Female 133 lb 11/8/2006 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 9/1/2006 54 Male 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/31/2006 39 Male 2/2/2007 Other Health Professional France
Primary
Secondary
Concomitant
Malaise Other Serious 1/12/2007 66 Female 2/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/17/2006 76 Female 3/7/2007 Consumer Italy
Primary
Concomitant
Somnolence Hospitalization 1/26/2007 81 Female 3/16/2007 Other Health Professional France
Primary
Concomitant
Sinus Tachycardia Other Serious 3/8/2007 11 Female 53 lb 3/30/2007 Physician United States
Primary
Concomitant
Refusal Of Treatment By Patient Required Intervention 11/3/2006 Female 93 lb 11/14/2006 Pharmacist United States
Primary
Concomitant
Blood Creatine Increased Required Intervention 4/24/2006 39 Male 237 lb 1/3/2007 United States
Primary
Concomitant
Somnolence Hospitalization 1/26/2007 81 Female 4/12/2007 Other Health Professional France
Primary
Concomitant
Pyrexia Hospitalization 2/9/2007 74 Male 4/14/2007 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Death 4/13/2006 42 Female 95 lb 5/7/2007 Physician Japan
Primary
Concomitant
Weight Increased Hospitalization 9/1/2006 Male 185 lb 6/15/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 167 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Intracardiac Thrombus Life Threatening 67 Female 117 lb 6/26/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 5/30/2007 Female 31 lb 6/28/2007 Pharmacist United States
Primary
Concomitant
Small Bowel Angioedema Hospitalization 6/12/2005 Male 174 lb 7/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Constipation Hospitalization 6/12/2005 Male 174 lb 7/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/11/2005 Female 7/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2003 60 Male 428 lb 8/9/2007 Pharmacist United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/20/2006 70 Male 8/15/2007 United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/9/2007 Male 249 lb 6/7/2007 United States
Primary
Concomitant
Syncope Hospitalization 2/3/2007 76 Female 8/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/1/2006 Male 199 lb 9/11/2007 Lawyer United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 5/30/2007 Female 31 lb 9/17/2007 Pharmacist
Primary
Concomitant
Staphylococcal Infection Other Serious 7/11/2007 Male 243 lb 9/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 9/18/2006 52 Male 9/29/2007 Japan
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 57 Male 10/2/2007
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 9/18/2006 52 Male 10/9/2007 Japan
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 4/1/2007 Female 10/18/2007 Physician France
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 8/25/2007 42 Female 123 lb 10/19/2007 Physician Japan
Primary
Concomitant
Quadriplegia Hospitalization 4/1/2007 Female 170 lb 10/22/2007 Physician France
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 8/25/2007 42 Female 123 lb 10/26/2007 Physician Japan
Primary
Secondary
Concomitant
Infection Life Threatening 7/8/2007 19 Male 164 lb 10/4/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/1/2006 Male 199 lb 12/4/2007 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 73 Male 12/7/2007 United Kingdom
Primary
Concomitant
Transplant Failure Hospitalization 12/13/2007 53 Male 225 lb 12/13/2007 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Life Threatening 7/15/2007 Male 12/20/2007 Physician United States
Primary
Secondary
Concomitant
Gastric Disorder Other Serious 1/1/2006 46 Male 198 lb 1/9/2008 Physician United Kingdom
Primary
Concomitant
Deafness Disability 10/25/2007 70 Female 234 lb 12/27/2007 Pharmacist United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 11/21/2006 2/14/2008 Physician Canada
Primary
Concomitant
Tremor Life Threatening 7/15/2007 Male 2/15/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 8/24/2007 43 Male 2/20/2008 Physician United States
Primary
Concomitant
Visual Field Defect Other Serious 12/13/2007 Female 2/22/2008 Physician France
Primary
Concomitant
Stevens-johnson Syndrome Required Intervention 11/6/2007 48 Female 265 lb 2/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Metastatic Malignant Melanoma Hospitalization 12/27/2007 49 Male 3/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/18/2008 Male 99 lb 2/19/2008 Physician United States
Primary
Concomitant
Neutropenia Other Serious 2/18/2008 86 Female 3/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Retinoic Acid Syndrome Required Intervention 1/4/2008 57 Female 206 lb 2/20/2008 United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 9/3/2007 54 Male 286 lb 3/7/2008 Pharmacist United States
Primary
Concomitant
Psychomotor Hyperactivity Other Serious 1/1/2003 Female 160 lb 5/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 4/18/2008 61 Female 5/14/2008 Physician
Primary
Concomitant
Vomiting Life Threatening 7/1/2006 Male 199 lb 6/12/2008 Lawyer United States
Primary
Secondary
Concomitant
Heart Rate Decreased Life Threatening 4/22/2008 Male 111 lb 4/24/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/22/2008 Male 6/18/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 7/3/2008 Physician United Kingdom
Primary
Concomitant
Metastatic Malignant Melanoma Hospitalization 12/27/2007 49 Male 7/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 7/21/2006 62 Female 190 lb 7/9/2008 Physician United Kingdom
Primary
Concomitant
Wheezing Other Serious 6/1/2008 58 Female 7/25/2008 Consumer United Kingdom
Primary
Concomitant
Tuberculous Pleurisy Hospitalization 4/1/2007 Female 130 lb 8/1/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/1/2006 Male 199 lb 8/4/2008 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 4/1/2008 Female 275 lb 8/7/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/1/2006 Male 199 lb 8/8/2008 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 70 Female 8/8/2008 Physician Israel
Primary
Concomitant
Vomiting Life Threatening 7/1/2006 Male 199 lb 8/13/2008 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 4/1/2008 Female 275 lb 8/14/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/1/2006 Male 199 lb 8/22/2008 Lawyer United States
Primary
Secondary
Concomitant
Paraesthesia 7/1/2008 Male 185 lb 8/27/2008 United States
Primary
Concomitant
Pruritus 5/1/2008 Female 222 lb 8/29/2008 Consumer United States
Primary
Concomitant
Fatigue 1/1/2006 Male 140 lb 9/2/2008 Consumer United States
Primary
Concomitant
Sepsis Death 22 Male 8/28/2008 Pharmacist United States
Primary
Concomitant
Death Death 8/22/2008 Male 174 lb 9/12/2008 Canada
Primary
Concomitant
Leukopenia Death 9/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 7/31/2008 Female 9/17/2008 Physician United Kingdom
Primary
Concomitant
Suture Removal Other Serious 8/11/2006 10 Female 57 lb 9/29/2008 United States
Primary
Concomitant
Vomiting Life Threatening 7/1/2006 Male 199 lb 9/30/2008 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/1/2006 Male 199 lb 10/1/2008 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/1/2006 Male 199 lb 10/6/2008 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/1/2006 Male 199 lb 10/7/2008 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 10/10/2008 Physician United States
Primary
Secondary
Concomitant
Scleral Haemorrhage Life Threatening 9/25/2008 66 Female 10/28/2008 Physician Japan
Primary
Secondary
Concomitant
Haemolytic Uraemic Syndrome Hospitalization 9/11/2006 Female 154 lb 10/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Scleral Haemorrhage Life Threatening 9/21/2008 66 Female 11/4/2008 Physician Japan
Primary
Secondary
Concomitant

Drug Data