Lansoprazole combined with Levofloxacin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Skin Discolouration Required Intervention 8/23/2005 Female 9/2/2005 United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 12/6/2005 69 Female 148 lb 1/27/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 12/29/2001 79 Male 10/11/2005 Physician United States
Primary
Secondary
Concomitant
Delirium Hospitalization 6/25/2005 Female 3/17/2006 Physician Japan
Primary
Concomitant
Neutropenic Sepsis Hospitalization 12/6/2005 69 Female 148 lb 3/15/2006 United Kingdom
Primary
Secondary
Concomitant
Hallucination Other Serious 62 Female 3/31/2006 Pharmacist United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 12/6/2005 69 Female 148 lb 3/29/2006 United Kingdom
Primary
Secondary
Concomitant
Hallucination Other Serious 62 Female 4/14/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Required Intervention 12/2/2005 60 Male 161 lb 12/29/2005 United States
Primary
Concomitant
Tachypnoea 5/4/2006 16 Female 144 lb 5/12/2006 Pharmacist United States
Primary
Concomitant
Tachypnoea Required Intervention 5/4/2006 16 Female 144 lb 5/18/2006 Physician United States
Primary
Concomitant
Tachypnoea Required Intervention 5/4/2006 16 Female 144 lb 6/12/2006 Physician United States
Primary
Concomitant
Therapeutic Product Contamination Required Intervention 5/4/2006 16 Female 144 lb 6/23/2006 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 5/29/2006 76 Female 7/26/2006 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 6/25/2006 50 Female 117 lb 8/11/2006 Physician Japan
Primary
Concomitant
Malaise Hospitalization 6/25/2006 50 Female 117 lb 8/17/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/16/2006 37 Male 9/21/2006 Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/26/2005 67 Female 10/11/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 12/6/2005 70 Female 148 lb 10/20/2006 Physician United States
Primary
Secondary
Concomitant
Tendonitis Other Serious 8/7/2006 55 Female 10/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/21/2005 37 Male 11/22/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/1/2006 61 Female 121 lb 12/14/2006 Physician Japan
Primary
Concomitant
Pneumonia Required Intervention 7/23/2006 68 Female 148 lb 7/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/26/2005 67 Female 2/12/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/26/2005 67 Female 2/16/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 74 Female 2/16/2007 Pharmacist Japan
Primary
Concomitant
Leukopenia Other Serious 7/27/2005 50 Female 160 lb 10/23/2006 Pharmacist United States
Primary
Secondary
Concomitant
Reiter's Syndrome Other Serious 1/12/2007 69 Male 3/27/2007 Other Health Professional Japan
Primary
Concomitant
Reiter's Syndrome Other Serious 1/12/2007 69 Male 4/12/2007 Other Health Professional Japan
Primary
Concomitant
Urinary Tract Infection Death 1/4/2007 92 Female 4/3/2007 Japan
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/4/2007 92 Female 5/24/2007 Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/4/2007 92 Female 6/1/2007 Japan
Primary
Secondary
Concomitant
Bursitis Hospitalization 5/14/2007 Female 121 lb 6/27/2007 Italy
Primary
Concomitant
Bursitis Hospitalization 5/14/2007 Female 121 lb 7/12/2007 Italy
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/1/2007 70 Male 154 lb 7/13/2007 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Disability 2/14/2007 67 Female 121 lb 7/13/2007 Physician Japan
Primary
Concomitant
Bursitis Infective Hospitalization 5/14/2007 Female 121 lb 8/10/2007 Italy
Primary
Concomitant
Urine Output Decreased Other Serious 2/14/2007 67 Female 121 lb 8/6/2007 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 2/24/2007 Female 88 lb 8/22/2007 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/25/2007 86 Female 77 lb 8/22/2007 Pharmacist Japan
Primary
Concomitant
Sinus Bradycardia Life Threatening 4/12/2007 Female 127 lb 4/16/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 7/25/2007 86 Female 77 lb 8/29/2007 Pharmacist Japan
Primary
Concomitant
Leukoencephalopathy Other Serious 12/5/2006 70 Female 9/3/2007 Pharmacist Japan
Primary
Secondary
Interstitial Lung Disease Hospitalization 5/1/2007 70 Male 9/5/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/16/2007 59 Female 10/16/2007 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 8/16/2007 Female 10/17/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 9/2/2007 77 Male 132 lb 10/22/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 8/16/2007 Female 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Varicella Life Threatening 8/16/2007 59 Female 10/26/2007 Japan
Primary
Secondary
Ventricular Fibrillation Hospitalization 10/4/2007 71 Female 157 lb 10/5/2007 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/16/2007 59 Female 11/30/2007 Japan
Primary
Secondary
Parvovirus Infection Hospitalization 10/20/2003 Male 176 lb 2/8/2008 United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/4/2008 63 Female 90 lb 2/4/2008 Physician Japan
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 12/6/2005 70 Female 148 lb 3/31/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/6/2007 66 Male 139 lb 4/7/2008 Physician Japan
Primary
Concomitant
Parvovirus Infection Hospitalization 10/20/2003 Male 176 lb 4/18/2008 United States
Primary
Concomitant
Pyrexia Hospitalization 4/6/2008 77 Male 4/23/2008 Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/11/2008 61 Male 211 lb 5/14/2008 Other Health Professional United States
Primary
Concomitant
Wheezing Hospitalization 5/13/2008 61 Male 211 lb 5/23/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/21/2007 25 Male 112 lb 6/4/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/6/2008 77 Male 6/1/2008 Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 2/19/2007 Male 117 lb 6/17/2008 Physician Japan
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 4/22/2008 82 Female 172 lb 5/2/2008 United States
Primary
Concomitant
Tremor Life Threatening 5/15/2008 Male 207 lb 5/23/2008 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 8/16/2007 Female 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 3/30/2008 76 Male 6/23/2008 Japan
Primary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 112 lb 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/22/2008 71 Female 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Tumour Flare Hospitalization 5/13/2008 61 Male 211 lb 6/17/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/21/2007 25 Male 112 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 2/1/2008 86 Female 118 lb 7/24/2008 United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 112 lb 7/28/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 22 Male 8/28/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 7/9/2008 81 Female 101 lb 8/29/2008 Physician Japan
Primary
Concomitant
Leukopenia Death 9/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Death 11/7/2007 42 Male 142 lb 9/22/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 7/9/2007 66 Male 139 lb 9/29/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/9/2008 81 Female 101 lb 10/1/2008 Physician Japan
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 10/1/2008 44 Female 10/24/2008 Pharmacist United States
Primary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 10/20/2008 49 Male 198 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 8/18/2008 54 Male 8/25/2008 Pharmacist United States
Primary
Concomitant
Rash Other Serious 2/25/2006 69 Female 137 lb 12/3/2008 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Death 3/18/2008 Male 190 lb 12/24/2008 Other Health Professional Turkey
Primary
Concomitant
Vomiting Other Serious 7/9/2007 66 Male 139 lb 12/23/2008 Physician Japan
Primary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Hypoglycaemia Other Serious 8/15/2008 Male 4/3/2009 Physician Japan
Primary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 4/14/2009 United States
Primary
Concomitant
Cachexia Death 3/13/2009 Male 5/13/2009 Other Health Professional Italy
Primary
Concomitant
Hypoaesthesia Facial Hospitalization 3/3/2009 63 7/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/20/2009 39 Female 119 lb 7/7/2009 Other Health Professional Japan
Primary
Concomitant
Lethargy Hospitalization 3/3/2009 Male 7/15/2009 Consumer United States
Primary
Secondary
Concomitant
Sepsis Other Serious 7/9/2007 66 Male 139 lb 7/10/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/27/2009 39 Female 119 lb 7/17/2009 Other Health Professional Japan
Primary
Concomitant
Hypoaesthesia Facial Hospitalization 3/2/2009 Male 8/18/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 66 Male 207 lb 9/1/2009 Physician Italy
Primary
Concomitant
Palmar Erythema Life Threatening 6/4/2009 23 Female 230 lb 6/5/2009 Pharmacist United States
Primary
Concomitant
Hypoaesthesia Facial Hospitalization 3/2/2009 Male 10/23/2009 Consumer United States
Primary
Secondary
Concomitant
Lethargy Hospitalization 3/2/2009 Male 10/23/2009 Consumer United States
Primary
Secondary
Concomitant
Hypoaesthesia Facial Hospitalization 3/2/2009 Male 10/28/2009 Consumer United States
Primary
Secondary
Concomitant
Lethargy Hospitalization 3/2/2009 Male 10/28/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 66 Male 207 lb 11/4/2009 Physician Italy
Primary
Concomitant
Retroperitoneal Haemorrhage Life Threatening 8/19/2009 Female 88 lb 12/8/2009 Physician Japan
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 11/3/2009 24 Female 108 lb 11/17/2009 Pharmacist United States
Primary
Concomitant
Somnolence Required Intervention 10/20/2009 25 Female 206 lb 10/21/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 8/19/2009 81 Female 88 lb 1/4/2010 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Death 10/1/2009 52 Male 12/22/2009 Physician Japan
Primary
Concomitant
No Therapeutic Response Death 7/31/2009 76 Male 121 lb 12/14/2009 Physician Japan
Primary
Concomitant
Stress Other Serious 10/11/2007 56 Female 98 lb 12/31/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/11/2007 56 Female 98 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 8/19/2009 81 Female 88 lb 2/18/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/10/2009 Female 104 lb 3/4/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/27/2009 39 Female 119 lb 4/8/2010 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/27/2009 39 Female 119 lb 5/11/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 8/25/2009 79 Male 5/4/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/27/2009 39 Female 119 lb 5/19/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/6/2010 39 Male 143 lb 5/25/2010 Consumer Japan
Primary
Concomitant
Pyrexia Other Serious 4/6/2010 39 Male 143 lb 6/11/2010 Consumer Japan
Primary
Concomitant
Wheezing Other Serious 5/26/2010 79 Female 7/2/2010 Other Health Professional Japan
Primary
Concomitant
Respiratory Disorder Death 7/31/2009 76 Male 121 lb 6/28/2010 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/19/2010 United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/16/2009 76 Male 176 lb 7/21/2010 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 8/6/2010 United States
Primary
Secondary
Concomitant
Gingival Bleeding Hospitalization 7/19/2010 76 Male 8/11/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 9/16/2007 49 Male 303 lb 8/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/16/2008 41 Male 225 lb 8/23/2010 Lawyer United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 8/4/2010 59 Male 9/1/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/26/2009 39 Female 119 lb 9/9/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 9/17/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/16/2008 41 Male 225 lb 9/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/10/2009 74 Female 104 lb 9/24/2010 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 6/16/2009 76 Male 176 lb 9/20/2010 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/2/2009 39 Female 119 lb 10/21/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 7/12/2010 72 Male 11/3/2010 Physician Switzerland
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Life Threatening 10/4/2010 46 Male 11/3/2010 Physician Japan
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 8/4/2010 59 Male 11/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 76 Female 11/9/2010 Italy
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Life Threatening 10/4/2010 46 Male 11/18/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/17/2010 Male 168 lb 11/22/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 11/22/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/12/2010 12/1/2010 Consumer Japan
Primary
Concomitant
Vomiting Hospitalization 76 Female 11/23/2010 Italy
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/15/2008 60 Male 12/15/2010 Other Health Professional United States
Primary
Concomitant

Drug Data