Lansoprazole combined with Leflunomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteoarthritis Other Serious 8/1/2005 Female 135 lb 1/27/2006 United States
Primary
Concomitant
Vasculitis Death 32 Female 176 lb 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/27/2006 57 Female 2/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 5/9/2005 58 Female 150 lb 12/27/2005 Other Health Professional United States
Primary
Concomitant
Renal Colic Hospitalization 10/28/2005 Male 209 lb 6/2/2006 Italy
Primary
Concomitant
Tachycardia Other Serious 7/24/2006 Female 106 lb 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cerebral Infarction Other Serious Male 170 lb 10/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Disease Hospitalization 11/25/2005 Female 146 lb 11/13/2006 Physician United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/6/2006 Female 11/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Death 9/13/2006 Female 163 lb 12/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 4/15/2006 Female 143 lb 12/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Fibrillation Hospitalization Male 12/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 12/27/2006 Germany
Primary
Concomitant
Syncope Hospitalization 4/29/2005 Female 104 lb 1/17/2007 Consumer United Kingdom
Primary
Concomitant
Rectal Haemorrhage Death 9/13/2006 Female 163 lb 1/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Psoriasis Other Serious 9/30/2006 40 Female 2/13/2007
Primary
Concomitant
Psoriasis Other Serious 9/30/2006 40 Female 2/27/2007
Primary
Concomitant
Lymphocytosis Hospitalization 11/17/2005 Female 3/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 6/17/2006 Female 161 lb 4/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Blistering Other Serious Female 6/4/2007 Physician United Kingdom
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 5/15/2007 Female 108 lb 6/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious 9/1/2004 Female 238 lb 7/5/2007 Consumer United Kingdom
Primary
Concomitant
Joint Dislocation Hospitalization 7/9/2007 Female 146 lb 7/19/2007 United Kingdom
Primary
Concomitant
Rheumatoid Nodule Hospitalization 10/28/2004 Male 168 lb 7/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Anaemia Hospitalization 8/23/2006 Female 93 lb 8/3/2007 United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 8/15/2007 Female 170 lb 9/6/2007 United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 5/15/2007 Female 108 lb 9/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 63 Female 150 lb 10/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tinnitus Disability 1/1/2007 Female 267 lb 11/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Psoriasis Hospitalization 2/20/2007 Male 148 lb 11/13/2007 United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 8/15/2007 Female 170 lb 11/29/2007 United Kingdom
Primary
Concomitant
Viral Infection Hospitalization 12/20/2006 Male 146 lb 12/7/2007 United Kingdom
Primary
Concomitant
Swelling 1/1/2005 Female 163 lb 12/14/2007 Other Health Professional United States
Primary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 12/19/2007 Germany
Primary
Concomitant
Interstitial Lung Disease Death 9/23/2007 80 1/16/2008
Primary
Concomitant
Renal Ischaemia Death 10/3/2007 Female 104 lb 2/25/2008 United Kingdom
Primary
Concomitant
Accidental Exposure 12/20/2007 Female 120 lb 3/14/2008 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Death 9/23/2007 80 4/4/2008
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/29/2007 Female 187 lb 4/25/2008 United Kingdom
Primary
Concomitant
Respiratory Disorder Hospitalization 12/19/2007 Female 137 lb 6/6/2008 United Kingdom
Primary
Concomitant
Injection Site Warmth 4/27/2008 Female 137 lb 6/13/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 5/16/2006 Female 121 lb 6/23/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 9/12/2005 53 Female 7/10/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/15/2007 Female 187 lb 7/11/2008 United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 11/1/2007 80 Female 187 lb 7/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Leg Amputation Hospitalization 6/11/2007 Female 196 lb 7/16/2008 United Kingdom
Primary
Concomitant
Skin Cancer Other Serious 6/19/2006 Male 161 lb 7/21/2008 United Kingdom
Primary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 7/25/2008 Germany
Primary
Concomitant
Pneumonia Other Serious 54 Female 146 lb 8/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pericarditis Other Serious 10/1/2007 Female 144 lb 9/12/2008 United States
Primary
Concomitant
Vomiting Hospitalization 7/23/2008 Female 9/12/2008 United States
Primary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 9/18/2008 Germany
Primary
Concomitant
Skin Cancer Hospitalization 8/31/2007 Female 132 lb 10/7/2008
Primary
Concomitant
Encephalitis Hospitalization 5/13/2008 Female 170 lb 10/8/2008 United Kingdom
Primary
Concomitant
Renal Failure Other Serious 5/7/2008 54 Female 146 lb 10/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious Male 152 lb 10/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Hospitalization 12/19/2007 Female 137 lb 10/17/2008 United Kingdom
Primary
Concomitant
Rectal Haemorrhage Death 9/13/2006 Female 163 lb 10/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Death 9/13/2006 Female 163 lb 10/20/2008 United Kingdom
Primary
Concomitant
Pneumonia Death 7/14/2008 Female 154 lb 10/27/2008 United Kingdom
Primary
Concomitant
Surgery Hospitalization 2/22/2008 Female 163 lb 10/29/2008 United Kingdom
Primary
Concomitant
Vascular Operation Hospitalization 2/22/2008 Female 163 lb 10/31/2008 United Kingdom
Primary
Concomitant
Ovarian Cancer Other Serious 1/30/2007 Female 154 lb 12/9/2008 United Kingdom
Primary
Concomitant
Erythema Multiforme Disability 11/1/2008 Female 154 lb 12/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/30/2008 Female 170 lb 1/12/2009 United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 10/1/2008 Male 152 lb 1/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 6/30/2008 Female 155 lb 1/23/2009 United Kingdom
Primary
Concomitant
Erythema Multiforme Disability 52 Female 154 lb 1/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ulcer Other Serious 1/9/2009 Female 194 lb 1/29/2009 Physician South Africa
Primary
Secondary
Concomitant
Ulcer Other Serious 1/9/2009 Female 194 lb 2/4/2009 Physician South Africa
Primary
Secondary
Concomitant
Sepsis Death 10/24/2008 Female 2/10/2009 United Kingdom
Primary
Concomitant
Pneumonia Death 9/2/2008 Male 132 lb 2/12/2009 United Kingdom
Primary
Concomitant
Ulcer Other Serious 1/9/2009 Female 194 lb 2/13/2009 Physician South Africa
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious Male 152 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 10/24/2008 Female 2/16/2009 United Kingdom
Primary
Concomitant
Vulvovaginal Candidiasis Other Serious 1/9/2009 Female 194 lb 2/17/2009 Physician South Africa
Primary
Secondary
Concomitant
Vulvovaginal Candidiasis Other Serious 1/9/2009 Female 194 lb 2/25/2009 Physician South Africa
Primary
Secondary
Concomitant
Atrial Flutter Other Serious 1/22/2009 66 Female 3/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Injection Site Swelling Other Serious 12/1/2008 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Other Serious 9/15/2004 Female 134 lb 3/26/2009 Germany
Primary
Concomitant
Hypertension Other Serious 9/15/2004 Female 134 lb 3/27/2009 Germany
Primary
Concomitant
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 4/3/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization 9/15/2004 Female 134 lb 4/14/2009 Germany
Primary
Concomitant
Myocardial Infarction Death 3/1/2009 112 lb 4/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Breast Cancer In Situ Other Serious 12/12/2007 Female 115 lb 5/20/2009 United Kingdom
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 38 Female 6/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Hypertension Hospitalization 9/15/2004 Female 134 lb 6/5/2009 Germany
Primary
Concomitant
Abortion Spontaneous Other Serious 38 Female 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Skin Ulcer Other Serious Female 196 lb 6/26/2009 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/1/2009 Female 7/1/2009 Physician United Kingdom
Primary
Concomitant
Urosepsis Hospitalization Female 187 lb 7/1/2009 United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 4/1/2009 Female 240 lb 7/17/2009 United Kingdom
Primary
Concomitant
Breast Cancer In Situ Other Serious 12/12/2007 Female 115 lb 8/3/2009 United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/20/2009
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 60 Female 8/20/2009 United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 8/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/28/2009 Other Health Professional United Arab Emirates
Primary
Secondary
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 8/25/2009 United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 60 Female 9/3/2009 United Kingdom
Primary
Secondary
Concomitant
Incorrect Dose Administered 4/23/2007 Female 98 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 12/20/2007 Female 120 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Warmth 4/27/2008 Female 137 lb 9/12/2009 Consumer United States
Primary
Concomitant
Hypertensive Crisis Hospitalization 9/15/2004 Female 134 lb 9/16/2009 Germany
Primary
Concomitant
Skin Cancer Hospitalization 8/7/2009 Female 10/22/2009 Physician United Kingdom
Primary
Concomitant
Alopecia Totalis Other Serious 6/1/2009 39 Female 154 lb 11/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 63 Female 12/8/2009 United Kingdom
Primary
Secondary
Concomitant
Refractory Anaemia With Ringed Sideroblasts Other Serious 5/25/2006 Male 12/10/2009 Other Health Professional Spain
Primary
Concomitant
Myocardial Infarction Life Threatening 12/11/2008 57 Female 165 lb 12/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Atrial Flutter Other Serious 1/22/2009 66 Female 1/7/2010 Other Health Professional United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Hospitalization 8/7/2009 Female 1/26/2010 Physician United Kingdom
Primary
Concomitant
Hypertensive Crisis Hospitalization 9/15/2004 Female 134 lb 2/25/2010 Germany
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/15/2009 72 Female 5/31/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Tardive Dyskinesia Hospitalization 12/15/2009 72 Female 6/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Tardive Dyskinesia Other Serious 2/15/2009 72 Female 6/3/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 12/15/2009 72 Female 6/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Sudden Death Death 6/23/2010 51 Female 269 lb 6/29/2010 Physician Egypt
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 10/1/2009 68 Female 7/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Impaired Healing Other Serious Female 200 lb 9/22/2010 Consumer Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/1/2009 68 Female 9/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Post Procedural Infection Hospitalization 6/3/2007 69 Female 146 lb 9/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Impaired Healing Other Serious Female 200 lb 10/6/2010 Physician Canada
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 10/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 10/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 139 lb 10/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 10/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 139 lb 10/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 139 lb 11/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 8/1/2010 64 Female 128 lb 11/10/2010 Physician United Kingdom
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 11/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 1/1/2002 75 Female 138 lb 11/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Impaired Healing Other Serious Female 200 lb 11/22/2010 Physician Canada
Primary
Concomitant
Rheumatoid Arthritis 6/26/2010 12/23/2010 Physician United States
Primary
Concomitant
Abscess Jaw Death 9/28/2010 64 Female 1/26/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Lung Abscess Death 10/8/2009 78 Female 110 lb 1/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Of Jaw Hospitalization 9/28/2010 64 Female 2/15/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Blood Creatine Increased Other Serious 9/1/2008 60 Female 117 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Death 4/1/2010 63 Female 154 lb 3/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bronchiectasis Other Serious 2/22/2011 73 Female 5/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 4/20/2011 78 Female 115 lb 5/6/2011 Physician Italy
Primary
Concomitant
Dyspnoea Hospitalization 2/22/2011 73 Female 99 lb 5/6/2011 Other Health Professional United Kingdom
Primary
Concomitant
Bronchiectasis Hospitalization 2/22/2011 73 Female 5/9/2011 United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 4/20/2011 78 Female 115 lb 5/20/2011 Physician Italy
Primary
Concomitant
Vasculitic Rash Hospitalization 1/26/2011 16 Female 121 lb 7/13/2011 Physician France
Primary
Secondary
Concomitant

Drug Data