Lanirapid combined with Lasix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Life Threatening 92 Female 1/20/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2000 73 Female 3/10/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Ulcer Life Threatening 1/1/2000 72 Female 3/10/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Inflammation Death 4/15/2005 83 Male 3/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Postoperative Wound Infection Life Threatening 6/2/2006 74 Male 6/16/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 6/5/2006 83 Male 101 lb 6/26/2006 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 5/29/2006 Female 64 lb 7/7/2006 Physician Japan
Primary
Concomitant
Drug Eruption Hospitalization 6/23/2006 79 Male 7/10/2006 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemic Coma Life Threatening 6/2/2006 74 Male 7/10/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/29/2006 Female 64 lb 7/19/2006 Physician Japan
Primary
Concomitant
Drug Eruption Hospitalization 6/23/2006 79 Male 7/31/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/29/2006 Female 64 lb 8/3/2006 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 5/29/2006 Female 64 lb 8/3/2006 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 9/16/2004 81 Female 8/9/2006 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Other Serious 6/22/2006 45 Male 203 lb 8/9/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 5/29/2006 Female 64 lb 8/14/2006 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 5/29/2006 Female 64 lb 8/16/2006 Physician Japan
Primary
Concomitant
Tremor Other Serious 7/1/2006 74 Female 8/23/2006 Pharmacist Japan
Primary
Concomitant
Hypoglycaemia Life Threatening 8/14/2006 82 Female 90 lb 9/11/2006 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Other Serious 5/1/2006 45 Male 203 lb 9/14/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/24/2006 67 Female 99 lb 9/21/2006 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/22/2006 67 Female 9/28/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/29/2006 Female 64 lb 10/3/2006 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 6/5/2006 83 Male 101 lb 10/5/2006 Physician Japan
Primary
Concomitant
Atrioventricular Block Third Degree Life Threatening 6/15/2006 63 Male 104 lb 9/29/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 4/23/1999 7 Female 33 lb 10/9/2006 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/24/2006 67 Female 99 lb 10/18/2006 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 8/10/2006 70 Male 115 lb 10/25/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/24/2006 67 Female 99 lb 11/3/2006 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/24/2006 67 Female 11/6/2006 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 8/30/2006 62 Male 11/8/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 8/30/2006 62 Male 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/24/2006 67 Female 11/22/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/24/2006 67 Female 12/22/2006 Pharmacist Japan
Primary
Concomitant
Cardiac Failure Hospitalization 7/30/2005 68 Female 1/8/2007 Physician Japan
Primary
Concomitant
Hypoglycaemia Hospitalization 12/18/2006 69 Male 1/22/2007 Other Health Professional Japan
Primary
Concomitant
Oedema Other Serious 3/29/2001 Male 4/23/2007 Physician Japan
Primary
Concomitant
Hypoglycaemic Coma Life Threatening 3/26/2007 93 Female 5/16/2007 Physician Japan
Primary
Concomitant
Hypoglycaemic Coma Life Threatening 3/26/2007 93 Female 5/21/2007 Physician Japan
Primary
Concomitant
Embolism Other Serious 2/22/2002 65 Female 6/3/2007 Physician Japan
Primary
Concomitant
Embolism Other Serious 2/22/2002 65 Female 6/15/2007 Physician Japan
Primary
Concomitant
Cardiac Failure Acute Hospitalization 6/15/2007 Female 101 lb 6/27/2007 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemic Coma Life Threatening 3/26/2007 93 Female 7/5/2007 Physician Japan
Primary
Concomitant
Pulmonary Congestion Life Threatening 6/20/2007 78 Female 154 lb 7/30/2007 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/15/2007 Female 101 lb 7/31/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Congestion Life Threatening 6/20/2007 78 Female 154 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 9/14/2006 78 Male 8/16/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Life Threatening 8/17/2007 94 Female 8/23/2007 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 9/14/2006 78 Male 8/30/2007 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 9/14/2006 78 Male 9/7/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 9/14/2006 78 Male 9/10/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 9/14/2006 78 Male 9/12/2007 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 3/12/2007 83 Male 82 lb 9/13/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 1/1/2007 86 Male 128 lb 9/17/2007 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/28/2007 95 Female 79 lb 9/26/2007 Physician Japan
Primary
Concomitant
Floppy Iris Syndrome Other Serious 9/4/2007 71 Male 10/1/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/26/2007 58 Male 10/12/2007 Physician Japan
Primary
Concomitant
Floppy Iris Syndrome Other Serious 9/4/2007 Male 10/15/2007 Physician Japan
Primary
Secondary
Concomitant
Iris Atrophy Other Serious 9/1/2007 Male 10/29/2007 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Life Threatening 8/3/2007 58 Female 108 lb 11/20/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 11/6/2006 74 Female 128 lb 11/26/2007 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Death 11/6/2006 74 Female 128 lb 12/12/2007 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 5/10/2007 Male 102 lb 12/28/2007 Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 95 Female 79 lb 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 5/10/2007 Male 102 lb 3/17/2008 Japan
Primary
Concomitant
Renal Failure Death 8/2/2007 57 Female 3/21/2008 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/28/2007 95 Female 79 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
Sudden Death Hospitalization 5/1/2007 Female 4/17/2008 Japan
Primary
Concomitant
Cardiac Failure Hospitalization 5/10/2007 Male 102 lb 4/18/2008 Japan
Primary
Concomitant
Sudden Death Hospitalization 5/1/2007 Female 4/23/2008 Japan
Primary
Concomitant
Hypoglycaemic Encephalopathy Other Serious 93 Female 4/25/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 4/19/2008 72 Female 119 lb 4/29/2008 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 4/19/2008 72 Female 119 lb 5/22/2008 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 4/4/2008 Female 5/30/2008 Consumer Japan
Primary
Concomitant
Renal Failure Chronic Hospitalization 5/10/2007 Male 102 lb 6/3/2008 Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 4/19/2008 72 Female 119 lb 6/5/2008 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Death 78 Male 6/12/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 5/1/2007 Female 6/16/2008 Japan
Primary
Concomitant
Cardiac Failure Other Serious 5/23/2008 44 Male 6/20/2008 Other Health Professional Japan
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Male 6/24/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 6/16/2008 96 Female 7/1/2008 Physician Japan
Primary
Concomitant
Sudden Death Death 4/2/2007 78 Male 7/7/2008 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/7/2006 Male 161 lb 7/15/2008 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Death 5/23/2008 Male 121 lb 7/18/2008 Other Health Professional Japan
Primary
Concomitant
Cardiac Failure Life Threatening 10/6/2007 81 Male 132 lb 7/29/2008 Other Health Professional Japan
Primary
Concomitant
Cardiac Failure Life Threatening 10/6/2007 81 Male 132 lb 8/13/2008 Other Health Professional Japan
Primary
Concomitant
Sudden Death Death 4/2/2007 78 Male 8/25/2008 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 6/26/2008 Male 8/27/2008 Physician Japan
Primary
Concomitant
Cardiac Failure Life Threatening 10/6/2007 81 Male 132 lb 9/3/2008 Other Health Professional Japan
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 1/13/2007 Male 9/9/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/16/2008 Male 129 lb 10/3/2008 Physician Japan
Primary
Concomitant
Shock Life Threatening 8/18/2008 Female 10/7/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/10/2004 59 Male 123 lb 10/17/2008 Japan
Primary
Concomitant
Cardiac Failure Hospitalization 6/30/2007 82 Female 88 lb 10/29/2008 Other Health Professional Japan
Primary
Concomitant
Renal Failure Life Threatening 11/15/2007 86 Male 123 lb 11/5/2008 Other Health Professional Japan
Primary
Concomitant
Hyponatraemia Hospitalization 10/20/2008 66 Female 11/7/2008 Other Health Professional Japan
Primary
Concomitant
Hyponatraemia Hospitalization 10/19/2008 66 Female 11/12/2008 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/16/2008 Male 129 lb 11/12/2008 Physician Japan
Primary
Concomitant
Myocardial Infarction Hospitalization 3/31/2007 Female 11/12/2008
Primary
Concomitant
Interstitial Lung Disease Other Serious 7/7/2008 81 Female 73 lb 11/21/2008 Physician Japan
Primary
Concomitant
Hyponatraemia Hospitalization 10/19/2008 66 Female 11/28/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/19/2008 66 Female 12/1/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 1/22/2008 86 Male 123 lb 12/1/2008 Other Health Professional Japan
Primary
Concomitant
Portal Venous Gas Life Threatening 11/13/2008 12/11/2008 Other Health Professional Japan
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 4/5/2000 Female 86 lb 12/17/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 12/4/2008 12/31/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 7/7/2008 81 Female 73 lb 1/19/2009 Physician Japan
Primary
Concomitant
Myocardial Infarction Death 68 Male 99 lb 1/19/2009 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 12/4/2008 1/22/2009 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 6/30/2007 82 Female 88 lb 1/23/2009 Other Health Professional Japan
Primary
Concomitant
Respiratory Failure Death 11/17/2008 2/3/2009 Physician Japan
Primary
Concomitant
Tricuspid Valve Incompetence Life Threatening 9/15/2007 Female 86 lb 2/13/2009 Physician Japan
Primary
Secondary
Concomitant
Haemorrhagic Disorder Other Serious 11/6/2008 Female 2/26/2009 Physician Japan
Primary
Secondary
Concomitant
Pyothorax Hospitalization 6/27/2007 82 Female 88 lb 2/27/2009 Other Health Professional Japan
Primary
Concomitant
Ventricular Fibrillation Death 5/23/2008 Male 121 lb 4/3/2009 Other Health Professional France
Primary
Concomitant
Mental Disorder Other Serious 11/6/2008 Female 4/27/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/28/2008 66 5/18/2009 Physician Japan
Primary
Concomitant
Shock Other Serious 79 Male 5/29/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Death Death 4/28/2009 Male 141 lb 6/17/2009 Other Health Professional Japan
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 3/5/2009 84 Male 6/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 5/20/2009 79 Female 6/27/2009 Physician Japan
Primary
Secondary
Concomitant
Hyperuricaemia Hospitalization 4/7/2009 90 Male 7/7/2009 Other Health Professional Japan
Primary
Concomitant
Pulmonary Hypertension Other Serious 4/5/2007 Female 106 lb 8/26/2009 Physician Japan
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 3/5/2009 84 Male 8/25/2009 United States
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 3/9/2008 77 Male 10/2/2009 Japan
Primary
Concomitant
Cardiac Arrest Other Serious 9/10/2009 90 10/13/2009 Japan
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 3/9/2008 77 Male 11/6/2009 Japan
Primary
Concomitant
Liver Disorder Other Serious 8/12/2009 96 Female 84 lb 11/19/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 8/12/2009 96 Female 84 lb 12/28/2009 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 2/4/2010 Male 2/28/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 2/24/2010 65 Male 3/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 12/26/2008 Male 128 lb 3/11/2010 Physician Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 12/3/2009 85 Female 3/11/2010 Other Health Professional Japan
Primary
Concomitant
Anaphylactic Shock Other Serious 2/22/2010 82 Female 3/16/2010 Japan
Primary
Concomitant
Anaphylactic Shock Other Serious 2/22/2010 82 Female 3/25/2010 Japan
Primary
Concomitant
Pneumonia Hospitalization 7/31/2009 Female 3/30/2010 Physician Japan
Primary
Concomitant
Hyponatraemia Hospitalization 10/19/2008 66 Female 4/1/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 12/26/2008 80 Male 128 lb 4/9/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/1/2009 85 Female 5/25/2010 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 2/24/2010 65 Male 6/4/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Shock Hospitalization 7/31/2009 90 Female 6/8/2010 Physician Japan
Primary
Concomitant
Stent Placement Other Serious 12/14/2007 82 Male 130 lb 6/14/2010 Physician Japan
Primary
Concomitant
Oedema Other Serious 6/4/2010 86 Female 6/22/2010 Consumer Japan
Primary
Secondary
Oedema Other Serious 6/4/2010 86 Female 6/24/2010 Consumer Japan
Primary
Secondary
Rash Generalised Other Serious 3/1/2010 81 Male 6/30/2010 Physician Japan
Primary
Concomitant
Heart Rate Decreased Other Serious 80 Female 7/15/2010 Pharmacist Japan
Primary
Secondary
Subarachnoid Haemorrhage Death 1/28/2010 81 Male 7/15/2010 Physician Japan
Primary
Secondary
Concomitant
Stent Placement Other Serious 12/14/2007 82 Male 130 lb 8/4/2010 Physician Japan
Primary
Concomitant
Sciatica Other Serious 7/3/2010 96 Female 8/11/2010 Pharmacist Japan
Primary
Concomitant
Pyrexia Hospitalization 3/9/2010 49 Male 152 lb 8/26/2010 Physician Japan
Primary
Secondary
Concomitant

Drug Data