Lamotrigine combined with Zonisamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Treatment Noncompliance Hospitalization 8/8/2006 Male 8/15/2006 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 3/23/2007 34 Male 4/25/2007 Physician Korea, Republic Of
Primary
Concomitant
Drug Ineffective Male 250 lb 4/11/2008 Consumer United States
Primary
Concomitant
Drug Interaction Hospitalization 8/7/2008 25 Female 8/25/2008 Consumer United Kingdom
Primary
Secondary
Drug Interaction Hospitalization 8/7/2008 25 Female 8/26/2008 Other Health Professional United Kingdom
Primary
Interacting
Drug Interaction Hospitalization 8/7/2008 25 Female 8/28/2008 Other Health Professional United Kingdom
Primary
Interacting
Drug Interaction Other Serious 25 Female 9/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Convulsion Hospitalization 8/7/2008 25 Female 8/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Suicidal Ideation Hospitalization 8/10/2008 Male 209 lb 9/10/2008 Germany
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2008 48 Male 205 lb 12/19/2008 Pharmacist United States
Primary
Secondary
Concomitant
Temperature Intolerance Hospitalization 9/1/2008 50 Female 119 lb 2/12/2009 United Kingdom
Primary
Concomitant
Sudden Unexplained Death In Epilepsy Death 3/9/2009 Female 3/23/2009 Germany
Primary
Concomitant
Vomiting Other Serious 16 Male 106 lb 3/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 16 Male 3/30/2009 United Kingdom
Primary
Concomitant
Suicide Attempt Life Threatening 5/8/2009 17 Male 150 lb 5/12/2009 Physician United States
Primary
Secondary
Personality Change Disability 4/30/2009 Male 5/28/2009 Germany
Primary
Concomitant
Peritoneal Dialysis Hospitalization Male 152 lb 6/5/2009 Other Health Professional United States
Primary
Concomitant
Convulsion Male 6/11/2009 Physician United States
Primary
Secondary
Headache Other Serious 6/14/2009 47 Male 214 lb 6/24/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2004 35 Female 8/6/2009 Consumer United States
Primary
Secondary
Concomitant
Convulsion Other Serious Female 10/20/2009 Consumer United States
Primary
Secondary
Myocardial Infarction Life Threatening 12/8/2009 Female 161 lb 12/11/2009 United States
Primary
Concomitant
Drug Exposure During Pregnancy Female 12/17/2009 United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Female 12/18/2009 United Kingdom
Primary
Secondary
Completed Suicide Death 58 Male 2/2/2010 United States
Primary
Secondary
Myocardial Infarction Life Threatening 12/8/2009 Female 161 lb 2/24/2010 United States
Primary
Concomitant
Sunburn Required Intervention 14 Male 150 lb 1/19/2010 Pharmacist United States
Primary
Secondary
Concomitant
Completed Suicide Death 58 Male 3/5/2010 Other Health Professional United States
Primary
Secondary
Psychomotor Hyperactivity Other Serious 3 Male 3/23/2010 United States
Primary
Concomitant
Stillbirth Death 4/2/2010 United Kingdom
Primary
Secondary
Psychomotor Hyperactivity Other Serious 4 Male 4/9/2010
Primary
Concomitant
Psychomotor Hyperactivity Other Serious 3 Male 4/9/2010
Primary
Secondary
Knee Arthroplasty Hospitalization 3/15/2010 47 Female 4/6/2010 Consumer United States
Primary
Concomitant
Psychomotor Hyperactivity Other Serious 4 Female 4/12/2010
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 4/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Vertigo Other Serious 39 Female 4/27/2010 Austria
Primary
Concomitant
Nausea Hospitalization 3/15/2010 47 Female 6/9/2010 Consumer United States
Primary
Concomitant
Completed Suicide Death 58 Male 3/19/2010 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 27 Female 7/14/2010 Ireland
Primary
Secondary
Concomitant
Myoclonus Other Serious 11 Male 8/6/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 3/15/2010 47 Female 8/17/2010 Consumer United States
Primary
Concomitant
Phobia Hospitalization 8/1/2010 20 Male 8/18/2010 Physician Italy
Primary
Concomitant
Myoclonus Other Serious 11 Male 8/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyperammonaemic Encephalopathy Other Serious 5 Male 9/9/2010
Primary
Secondary
Phobia Hospitalization 8/1/2010 20 Male 9/14/2010 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 27 Female 9/29/2010 Ireland
Primary
Secondary
Concomitant
Pallor 8/9/2010 5 Male 9/8/2010 United States
Primary
Concomitant
Paranoia Other Serious 22 Female 10/21/2010 Other Health Professional Japan
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 3/15/2010 47 Female 11/5/2010 Physician United States
Primary
Concomitant
Paranoia Other Serious 22 Female 11/8/2010 Other Health Professional Japan
Primary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 11/12/2010 Norway
Primary
Secondary
Weight Bearing Difficulty Hospitalization 3/15/2010 47 Female 12/6/2010 Physician United States
Primary
Concomitant
Convulsion Other Serious 11/1/2010 20 Female 130 lb 1/4/2011 Consumer United States
Primary
Concomitant
Drug Interaction Other Serious 11/1/2010 3 Female 29 lb 2/8/2011 Physician Germany
Primary
Concomitant
Interacting
Speech Disorder Other Serious 21 Female 2/2/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 21 Female 2/4/2011 United Kingdom
Primary
Secondary
Concomitant
Depression Disability 5/1/2007 22 Female 2/25/2011 Physician Germany
Primary
Secondary
Dysarthria Hospitalization 22 Female 2/23/2011 Germany
Primary
Secondary
Rash Other Serious 2/1/2011 27 Female 3/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 1/1/2009 39 Male 3/7/2011 Physician Germany
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 10/1/2009 49 Male 3/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Malignant Melanoma Other Serious 10/1/2009 49 Male 3/30/2011 Consumer United Kingdom
Primary
Secondary
Balance Disorder Other Serious 37 Female 3/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 10/1/2009 49 Male 4/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Malignant Melanoma Other Serious 10/1/2009 49 Male 4/4/2011 Consumer United Kingdom
Primary
Secondary
Malignant Melanoma Other Serious 10/1/2009 49 Male 4/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Malignant Melanoma Other Serious 10/1/2009 49 Male 4/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Diplopia Other Serious 37 Female 3/28/2011 United Kingdom
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 10/1/2009 49 Male 3/22/2011 United States
Primary
Secondary
Malignant Melanoma Other Serious 10/1/2009 49 Male 3/30/2011 Consumer United Kingdom
Primary
Secondary
Malignant Melanoma Other Serious 10/1/2009 49 Male 4/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Malignant Melanoma Other Serious 10/1/2009 49 Male 4/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Abortion Spontaneous Other Serious Female 4/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 27 Female 5/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Brain Herniation Other Serious 27 Female 4/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Encephalocele Other Serious 27 Female 4/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Ineffective Other Serious 27 Female 4/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Encephalocele Other Serious 27 Female 5/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 27 Female 5/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective 27 Female 5/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Communication Disorder Other Serious 15 Male 8/15/2011 Physician Germany
Primary
Secondary
Concomitant
Convulsion Other Serious 67 Male 8/24/2011 Other Health Professional Japan
Primary
Concomitant
Thirst Other Serious 60 Female 9/2/2011 Consumer Japan
Primary
Concomitant
Malaise Other Serious 1/1/2008 67 Male 9/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Polydipsia Other Serious 60 Female 9/7/2011 Consumer Japan
Primary
Secondary
Concomitant
Convulsion Other Serious 1/30/2011 34 Male 9/9/2011 Pharmacist United Kingdom
Primary
Concomitant
Major Depression Hospitalization 11/10/2008 46 Female 8/8/2011 Consumer United States
Primary
Secondary
Concomitant
Psychomotor Retardation Other Serious Male 10/24/2011 Other Health Professional India
Primary
Secondary
Concomitant
Single Photon Emission Computerised Tomogram Abnormal Hospitalization 1 Female 11/8/2011 Other Health Professional Japan
Primary
Secondary
Somnolence Other Serious 2/14/2009 42 Female 11/23/2011 Consumer United States
Primary
Concomitant
Cognitive Disorder Hospitalization 1/1/2011 37 Male 11/28/2011 Physician France
Primary
Concomitant
Product Substitution Issue Other Serious 12/21/2011 35 Male 12/21/2011 Physician United States
Primary
Concomitant
Partial Seizures Other Serious 15 Male 2/9/2012 Other Health Professional Japan
Primary
Concomitant
Convulsion Other Serious 21 Female 2/7/2012 Other Health Professional United States
Primary
Secondary
Epilepsy Other Serious 15 Male 2/16/2012 Other Health Professional Japan
Primary
Secondary
Memory Impairment Hospitalization 1/10/2000 15 Female 12/13/2011 Consumer United States
Primary
Concomitant
Malaise Other Serious 29 Female 220 lb 12/13/2011 Consumer United States
Primary
Concomitant
Myoclonic Epilepsy Hospitalization 4/23/2011 6 Male 12/13/2011 United States
Primary
Concomitant
Oral Pain Other Serious 1/21/2012 2 Female 3/8/2012 Consumer United States
Primary
Concomitant
Pain Female 3/14/2012 Other Health Professional United States
Primary
Concomitant
Somnambulism Other Serious 15 Male 3/23/2012 Other Health Professional Japan
Primary
Concomitant
Brain Operation Hospitalization 56 Female 4/9/2012 Consumer United States
Primary
Concomitant
Partial Seizures Other Serious 31 Female 6/20/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Protrusion Tongue Other Serious 31 Female 7/9/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 31 Female 7/13/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Withdrawal Convulsions Other Serious 6/1/2012 7/17/2012 Physician United States
Primary
Concomitant
Drug Withdrawal Convulsions Other Serious 6/1/2012 19 Male 150 lb 7/2/2012 Consumer United States
Primary
Concomitant
Drug Withdrawal Convulsions Other Serious 6/1/2012 19 Male 150 lb 7/10/2012 Physician United States
Primary
Concomitant
Partial Seizures Other Serious 31 Female 7/10/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Movement Disorder Other Serious 31 Female 7/10/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 31 Female 7/10/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 31 Female 7/10/2012 Other Health Professional
Primary
Secondary
Concomitant
Convulsion Other Serious 24 Male 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Convulsion Other Serious 3 Female 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 17 Female 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Convulsion Other Serious 7 Male 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 20 Male 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Fall Other Serious 5 Male 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Fall Other Serious 6 Female 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 6 Female 8/16/2012 Physician Japan
Primary
Secondary
Concomitant
Atonic Seizures Other Serious 3 Female 8/16/2012 Physician Japan
Primary
Secondary
Concomitant
Atonic Seizures Other Serious 17 Female 8/16/2012 Physician Japan
Primary
Secondary
Concomitant
Atonic Seizures Other Serious 7 Male 8/16/2012 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 20 Male 8/16/2012 Physician Japan
Primary
Secondary
Concomitant
Atonic Seizures Other Serious 5 Male 8/16/2012 Physician Japan
Primary
Secondary
Concomitant
Atonic Seizures Other Serious 24 Male 8/16/2012 Physician Japan
Primary
Secondary
Concomitant
Thinking Abnormal Other Serious 6/1/2012 72 Male 8/3/2012 Consumer United States
Primary
Concomitant
Convulsion Other Serious Male 8/6/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Convulsion Other Serious Male 8/6/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Drop Attacks Other Serious Male 8/6/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Fall Other Serious Female 8/6/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Drop Attacks Other Serious Female 8/6/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 31 Female 7/31/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 24 Male 10/16/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 3 Female 10/16/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 17 Female 10/16/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 7 Male 10/16/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 20 Male 10/16/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 5 Male 10/16/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 6 Female 10/16/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Thinking Abnormal Other Serious 6/2012 72 Male 8/10/2012 Consumer Us
Primary
Concomitant
Injury Other Serious Male 8/16/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Male 8/16/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Head Injury Other Serious Male 8/16/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Head Injury Other Serious Female 8/16/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Head Injury Other Serious Female 8/16/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Orthostatic Hypotension Other Serious 9/4/2012 Physician Jp
Primary
Concomitant
Petit Mal Epilepsy Other Serious 2006 4 Male 9/14/2012 Consumer Us
Primary
Secondary
Concomitant
Eosinophilic Colitis Other Serious 58 Male 10/9/2012 Country Not Specified
Primary
Secondary
Inappropriate Affect Hospitalization 15 Male 10/23/2012 Jp
Primary
Concomitant

Drug Data