Lamotrigine combined with Valproic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thoracic Vertebral Fracture Other Serious 1/1/2005 39 Female 1/13/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 39 Female 159 lb 1/23/2006 Netherlands
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 3/17/2006 Other Health Professional Australia
Primary
Secondary
Tachycardia Other Serious 57 Female 4/5/2006 Consumer United Kingdom
Primary
Secondary
Tachycardia Other Serious 57 Female 5/10/2006 Consumer United Kingdom
Primary
Secondary
Interstitial Lung Disease Other Serious 57 Female 5/19/2006 Other Health Professional France
Primary
Interacting
Treatment Noncompliance Other Serious 10/29/2004 32 Female 5/18/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Tachycardia Other Serious 4/26/2006 57 Female 5/31/2006 Consumer United Kingdom
Primary
Concomitant
Tachycardia Other Serious 57 Female 7/3/2006 Consumer United Kingdom
Primary
Secondary
Tachycardia Other Serious 57 Female 7/3/2006 Consumer United Kingdom
Primary
Secondary
Pleural Effusion Hospitalization Female 7/5/2006 Pharmacist Canada
Primary
Secondary
Pleural Effusion Hospitalization 50 Female 7/7/2006 Pharmacist Canada
Primary
Concomitant
Rash Morbilliform Life Threatening 6/20/2006 16 Female 110 lb 7/11/2006 Pharmacist United States
Primary
Secondary
Lethargy Hospitalization 5/16/2006 56 Male 157 lb 7/16/2006 Pharmacist United States
Primary
Concomitant
Priapism 6/23/2006 Male 182 lb 9/8/2006 Pharmacist United States
Primary
Concomitant
Intentional Overdose Death 7/25/2006 23 Female 150 lb 10/26/2006 Physician Russian Federation
Primary
Concomitant
Viral Infection Required Intervention 8/11/2006 Male 8/18/2006 Pharmacist United States
Primary
Concomitant
Unevaluable Event Other Serious 11/5/2006 Male 156 lb 2/12/2007 Physician France
Primary
Concomitant
Irritability Other Serious Male 2/14/2007 Physician Belgium
Primary
Concomitant
Spina Bifida Congenital Anomaly Female 3/9/2007 United Kingdom
Primary
Secondary
Epilepsy Other Serious 16 Male 3/27/2007 Other Health Professional Brazil
Primary
Concomitant
Convulsion Other Serious 7/1/2005 48 Female 4/6/2007 Netherlands
Primary
Concomitant
Rash Other Serious 9/20/2006 10 Male 61 lb 3/5/2007 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 23 Female 6/7/2007 Turkey
Primary
Secondary
Urinary Tract Infection Hospitalization 23 Female 6/11/2007 Turkey
Primary
Secondary
Concomitant
Superinfection Hospitalization 11 Female 7/6/2007 Physician Saudi Arabia
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 10/1/2006 44 Female 7/27/2007 Physician Germany
Primary
Concomitant
Psychotic Disorder Hospitalization 52 Female 8/31/2007 Germany
Primary
Secondary
Concomitant
Ventricular Septal Defect Congenital Anomaly Male 5 lb 9/4/2007 Germany
Primary
Secondary
Hypospadias Congenital Anomaly Male 7 lb 9/4/2007 Germany
Primary
Secondary
Transaminases Increased Hospitalization 2 Female 9/22/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4 Male 10/17/2007 Consumer Turkey
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4 Male 10/19/2007 Consumer Turkey
Primary
Concomitant
Mood Swings Other Serious 44 Female 11/16/2007 France
Primary
Concomitant
Histiocytosis Haematophagic Other Serious 4 Male 11/30/2007 Turkey
Primary
Concomitant
Interacting
Histiocytosis Haematophagic Other Serious 4 Male 12/6/2007 France
Primary
Concomitant
Interacting
Weight Decreased Other Serious 45 Female 108 lb 12/11/2007 Consumer Brazil
Primary
Concomitant
Urethral Cancer Metastatic Other Serious 66 Male 12/14/2007 Physician Canada
Primary
Concomitant
Urethral Cancer Metastatic Death 5/7/2007 65 Male 12/18/2007 Physician Canada
Primary
Concomitant
Respiratory Rate Increased Hospitalization 36 Female 12/13/2007 Physician France
Primary
Concomitant
Hepatotoxicity Hospitalization 2 Female 1/8/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Drug Toxicity Death 42 Male 1/15/2008 Physician United States
Primary
Secondary
Drug Toxicity Death 42 Male 1/16/2008 Physician United States
Primary
Secondary
Unresponsive To Stimuli Hospitalization 36 Male 1/22/2008 Physician United States
Primary
Secondary
Pancreatitis Acute Hospitalization 12/26/2007 Male 163 lb 1/29/2008 Physician Germany
Primary
Secondary
Concomitant
Completed Suicide Death 42 Male 2/8/2008 United States
Primary
Secondary
Poisoning Death 42 Male 2/6/2008 Physician United States
Primary
Secondary
Death Death 1/1/2006 42 Male 2/11/2008 Physician United States
Primary
Secondary
Thrombocytopenic Purpura Other Serious 7/1/2006 19 Male 3/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Shock Syndrome Staphylococcal Other Serious 10/1/2007 11 Female 79 lb 3/13/2008 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 5/9/2007 Male 105 lb 4/11/2008 Consumer United States
Primary
Secondary
Interacting
Vision Blurred Hospitalization 3/1/2007 23 Female 4/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 49 Female 4/30/2008 Physician Spain
Primary
Secondary
Concomitant
Postictal State Hospitalization 11/25/2007 32 Male 150 lb 5/1/2008 Physician Germany
Primary
Concomitant
Abortion Spontaneous Other Serious 1/1/2001 Female 5/12/2008 Physician France
Primary
Concomitant
Grand Mal Convulsion Other Serious 6/10/1998 Female 5/15/2008 Other Health Professional France
Primary
Concomitant
Inhibitory Drug Interaction Other Serious 1/1/2008 2 Female 5/12/2008 Netherlands
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 1/1/2001 Female 5/19/2008 Lawyer France
Primary
Concomitant
Aggression Hospitalization 11/25/2007 32 Male 150 lb 5/8/2008 Physician Germany
Primary
Concomitant
Viral Infection Other Serious 7/19/2000 Male 7 lb 5/22/2008 Physician France
Primary
Concomitant
Drug Toxicity Hospitalization 36 Male 5/22/2008 Consumer Brazil
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 3/1/1984 Female 5/30/2008 Physician France
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 2 Female 6/2/2008 Other Health Professional Netherlands
Primary
Concomitant
Staring Other Serious 14 Female 6/19/2008 United States
Primary
Secondary
Concomitant
Talipes Congenital Anomaly 10/1/2006 7/9/2008 Other Health Professional Serbia
Primary
Secondary
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Hypospadias Congenital Anomaly Male 6 lb 9/3/2008 United Kingdom
Primary
Secondary
Myoclonic Epilepsy Hospitalization 2 Female 9/3/2008 Physician Netherlands
Primary
Concomitant
Convulsion Hospitalization 8/1/2008 5 Male 44 lb 9/5/2008 Other Health Professional Germany
Primary
Concomitant
Status Epilepticus Other Serious 4 Female 9/19/2008 United States
Primary
Secondary
Hepatotoxicity Other Serious 4 9/23/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3 Female 9/29/2008 United States
Primary
Secondary
Concomitant
Psoriasis Hospitalization 7/1/2008 14 Female 10/13/2008 Other Health Professional France
Primary
Concomitant
Completed Suicide Death 42 Male 10/30/2008 Physician United States
Primary
Secondary
Tremor Other Serious 72 Female 11/7/2008 Taiwan, Province Of China
Primary
Secondary
Concomitant
Peripheral Coldness Other Serious 11/4/2008 3 Female 24 lb 11/24/2008 Physician Mexico
Primary
Concomitant
Vision Blurred Hospitalization 3/1/2007 23 Female 12/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Autism Other Serious 12/16/2008 United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Other Serious 12/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psoriasis Hospitalization 7/1/2008 14 Female 12/22/2008 Other Health Professional France
Primary
Concomitant
Completed Suicide Death 18 Female 12/31/2008 Pharmacist United States
Primary
Secondary
Drug Exposure During Pregnancy Required Intervention 12/29/2008 United Kingdom
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 1/8/2009 Consumer United Kingdom
Primary
Secondary
Intentional Drug Misuse Death 1/1/2007 18 Female 1/6/2009 United States
Primary
Secondary
Completed Suicide Death 18 Female 1/15/2009 United States
Primary
Secondary
Completed Suicide Death 28 Female 1/16/2009 United States
Primary
Secondary
Urticaria Other Serious 11/25/2008 19 Female 101 lb 1/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Poisoning Death 18 Female 1/16/2009 Physician United States
Primary
Secondary
Poisoning Deliberate Death 28 Female 1/15/2009 Physician United States
Primary
Secondary
Completed Suicide Death 28 Female 1/21/2009 Physician United States
Primary
Secondary
Completed Suicide Death 18 Female 1/30/2009 Other Health Professional United States
Primary
Secondary
Vision Blurred Hospitalization 3/1/2007 23 Female 1/30/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Poisoning Deliberate Death 18 Female 1/26/2009 Physician United States
Primary
Secondary
Poisoning Deliberate Death 28 Female 1/26/2009 Physician United States
Primary
Secondary
Sweat Gland Disorder Hospitalization 9 Male 1/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 1/1/2007 28 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Death Death 1/1/2007 18 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Tinnitus Other Serious 1/15/2007 Male 2/6/2009 Consumer Mexico
Primary
Concomitant
Renal Failure Male 2/3/2009 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 20 Female 2/16/2009 Consumer Argentina
Primary
Concomitant
Vision Blurred Other Serious 3/1/2007 23 Female 2/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sweat Gland Disorder Hospitalization 9 Male 2/12/2009 United Kingdom
Primary
Secondary
Sweat Gland Disorder Hospitalization 2/23/2009 Other Health Professional United Kingdom
Primary
Interacting
Sweat Gland Disorder Hospitalization 9 Male 2/24/2009 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4 Female 2/19/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4 Female 2/24/2009 United States
Primary
Secondary
Concomitant
Sweat Gland Disorder Hospitalization 9 Male 2/21/2009 United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 2/27/2009 Consumer United Kingdom
Primary
Secondary
Sweat Gland Disorder Hospitalization 9 Male 2/27/2009 Consumer United Kingdom
Primary
Secondary
Urticaria Hospitalization 9 Male 2/17/2009 United Kingdom
Primary
Secondary
Sweat Gland Disorder Hospitalization 9 Male 3/6/2009 Consumer United Kingdom
Primary
Secondary
Thinking Abnormal Hospitalization 36 Male 3/5/2009 Other Health Professional Brazil
Primary
Secondary
Concomitant
Therapy Regimen Changed Other Serious 36 Male 3/16/2009 Other Health Professional Brazil
Primary
Secondary
Concomitant
Vision Blurred Other Serious 23 Female 4/3/2009 United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Other Serious 23 Female 4/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyskinesia Other Serious 1/26/2009 14 Male 4/4/2009 Canada
Primary
Concomitant
Speech Disorder Hospitalization 1/1/2005 Male 4/17/2009 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 4 Male 4/14/2009 Physician Turkey
Primary
Secondary
Speech Disorder Hospitalization 1/1/2005 Male 4/28/2009 Physician Germany
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2007 18 Female 5/7/2009 Physician United States
Primary
Secondary
Urticaria Hospitalization 38 Male 5/21/2009 Physician Germany
Primary
Secondary
Troponin T Increased Life Threatening 11 Female 5/19/2009 United Kingdom
Primary
Secondary
Somnolence Life Threatening 11 Female 5/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Somnolence Life Threatening 11 Female 5/22/2009 United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 5 Female 6/1/2009 Consumer Turkey
Primary
Secondary
Vomiting Death 36 Male 6/4/2009 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 11 Female 6/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 11 Female 6/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data