Lamotrigine combined with Topiramate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Torsade De Pointes Other Serious 7/7/2004 44 Male 122 lb 2/7/2006 Physician Spain
Primary
Secondary
Concomitant
Pyloric Stenosis Congenital Anomaly 5 lb 2/2/2006 United Kingdom
Primary
Secondary
Pneumonia Hospitalization 1/7/2006 13 Female 28 lb 2/17/2006 Physician Mexico
Primary
Concomitant
Onychoclasis Other Serious 11/1/2005 60 Female 5/16/2006 Consumer Australia
Primary
Concomitant
Speech Disorder Other Serious 3/24/2006 52 Male 292 lb 3/27/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 4/1/2005 15 Male 55 lb 5/25/2006 Physician Spain
Primary
Concomitant
Petit Mal Epilepsy Other Serious 15 Male 6/15/2006 Consumer United Kingdom
Primary
Secondary
Vomiting Hospitalization 1/1/2006 Female 6/1/2006 Physician Denmark
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 1/25/2006 43 Male 150 lb 3/21/2006 United States
Primary
Secondary
Concomitant
Tonic Convulsion 29 Male 212 lb 1/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 3/9/2006 22 Male 5/9/2006 Consumer United States
Primary
Concomitant
Abortion Spontaneous Other Serious 2/1/2006 36 Female 9/15/2006 Other Health Professional France
Primary
Concomitant
Fatigue Other Serious 9/14/2006 40 Female 10/19/2006 Physician Sweden
Primary
Concomitant
Fatigue Other Serious 9/14/2006 40 Female 10/27/2006 Other Health Professional Sweden
Primary
Concomitant
Drug Interaction Other Serious Female 157 lb 11/27/2006 Pharmacist Germany
Primary
Concomitant
Interacting
Weight Increased Other Serious 4/1/2005 37 265 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Petit Mal Epilepsy Other Serious 15 Male 1/29/2007 Other Health Professional France
Primary
Secondary
Pyloric Stenosis Congenital Anomaly Male 5 lb 1/22/2007 United Kingdom
Primary
Secondary
Psychiatric Symptom Other Serious 9/22/2006 Female 137 lb 2/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 Female 140 lb 2/21/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2005 37 Male 265 lb 2/21/2007 Consumer United States
Primary
Concomitant
Small For Dates Baby Congenital Anomaly Male 6 lb 3/5/2007 Consumer United Kingdom
Primary
Secondary
Small For Dates Baby Congenital Anomaly Male 5 lb 3/8/2007 Other Health Professional United Kingdom
Primary
Secondary
Small For Dates Baby Congenital Anomaly Male 3/12/2007 United Kingdom
Primary
Secondary
No Therapeutic Response Other Serious 7/1/2006 19 Male 3/21/2007 Physician United Kingdom
Primary
Secondary
Choanal Atresia Congenital Anomaly 5/1/2007 Physician Australia
Primary
Concomitant
Drug Exposure During Pregnancy Death 5/3/2005 Female 5/2/2007 Physician Australia
Primary
Concomitant
Suicidal Ideation Hospitalization 35 Female 5/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 1/27/2007 67 Male 229 lb 4/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 35 Female 6/1/2007 United States
Primary
Secondary
Concomitant
Postictal State Hospitalization 46 Male 6/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Other Serious Female 6/21/2007 Physician United Kingdom
Primary
Concomitant
Superinfection Hospitalization 11 Female 7/6/2007 Physician Saudi Arabia
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia Other Serious 12/25/2005 12 Female 8/2/2007 Physician Thailand
Primary
Secondary
Electroencephalogram Abnormal Other Serious 16 Male 9/6/2007 Belgium
Primary
Concomitant
Interacting
Transaminases Increased Hospitalization 2 Female 9/22/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Convulsion Other Serious 11/1/2006 6 Male 42 lb 10/1/2007 United States
Primary
Concomitant
Spinal Column Stenosis Other Serious 8/1/2005 Female 11/9/2007 Consumer United States
Primary
Concomitant
Hallucination, Visual Other Serious 9/28/2007 34 Male 11/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Hospitalization 10/12/2007 74 Male 95 lb 11/15/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Convulsion Other Serious 11/21/2007 Female 117 lb 11/23/2007 Pharmacist United States
Primary
Concomitant
Hepatotoxicity Hospitalization 2 Female 1/8/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Petit Mal Epilepsy Other Serious 39 Female 1/10/2008 Other Health Professional France
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 7/1/2006 19 Male 3/3/2008 Consumer United Kingdom
Primary
Secondary
Thrombocytopenic Purpura Other Serious 7/1/2006 19 Male 3/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenic Purpura Other Serious 7/1/2006 19 Male 3/7/2008 Physician United Kingdom
Primary
Secondary
Thrombocytopenic Purpura Other Serious 7/1/2006 19 Male 3/14/2008 Other Health Professional France
Primary
Secondary
Liver Injury Other Serious 3/25/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Epilepsy Other Serious 12/15/2007 29 Male 3/28/2008 Other Health Professional France
Primary
Concomitant
Interacting
Hemiplegia Other Serious 11 Female 3/31/2008 Other Health Professional United States
Primary
Secondary
Stevens-johnson Syndrome Other Serious 3/23/2007 Male 30 lb 4/11/2008 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 4/15/2008 Consumer United States
Primary
Secondary
Concomitant
Myopia Other Serious 25 Female 4/22/2008 Physician Australia
Primary
Concomitant
Visual Acuity Reduced Disability 46 5/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 52 Female 123 lb 5/8/2008 Physician France
Primary
Concomitant
Visual Acuity Reduced Hospitalization 46 5/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Inhibitory Drug Interaction Other Serious 1/1/2008 2 Female 5/12/2008 Netherlands
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 5/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 5/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Visual Acuity Reduced Disability 46 5/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 5/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 6/2/2008 Consumer United Kingdom
Primary
Concomitant
No Adverse Event 46 6/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 6/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 2 Female 6/2/2008 Other Health Professional Netherlands
Primary
Concomitant
Premature Labour Other Serious 10/31/2007 Female 157 lb 6/9/2008 United States
Primary
Concomitant
Drug Eruption Hospitalization 12/1/2007 36 Male 187 lb 6/3/2008 Physician Switzerland
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 6/12/2008 Other Health Professional United States
Primary
Concomitant
Skin Atrophy 1/1/2007 Female 165 lb 6/13/2008 Consumer United States
Primary
Concomitant
Torticollis Congenital Anomaly 4/1/2004 7/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 7/9/2008 Physician United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 7/9/2008 Other Health Professional Australia
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 7/9/2008 Physician United Kingdom
Primary
Secondary
Talipes Congenital Anomaly 10/1/2006 7/9/2008 Other Health Professional Serbia
Primary
Secondary
Stillbirth Other Serious Female 7/10/2008 Other Health Professional Serbia
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 7/10/2008 Other Health Professional United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 7/10/2008 Other Health Professional Denmark
Primary
Secondary
Multiple Drug Overdose Death 1/1/2006 50 Male 7/7/2008 Canada
Primary
Secondary
Concomitant
Hemiplegia Other Serious 11 Female 7/23/2008 Physician Netherlands
Primary
Secondary
Coronary Artery Occlusion Hospitalization 1/1/2006 Female 150 lb 8/11/2008 Consumer United States
Primary
Concomitant
Simple Partial Seizures Other Serious 7/25/2008 26 Female 8/22/2008 Other Health Professional South Africa
Primary
Concomitant
Anal Atresia Congenital Anomaly Female 8/28/2008 United Kingdom
Primary
Secondary
Dysmorphism Congenital Anomaly Female 8/28/2008 United Kingdom
Primary
Secondary
Hip Dysplasia Congenital Anomaly Female 7 lb 8/28/2008 Physician United Kingdom
Primary
Secondary
Pyloric Stenosis Congenital Anomaly Male 5 lb 9/2/2008 United Kingdom
Primary
Secondary
Congenital Hydronephrosis Congenital Anomaly Male 5 lb 9/2/2008 United Kingdom
Primary
Secondary
Penis Disorder Congenital Anomaly Male 5 lb 9/2/2008 United Kingdom
Primary
Secondary
Hydrocele Congenital Anomaly Female 9/3/2008 United Kingdom
Primary
Secondary
Joint Dislocation Congenital Anomaly Female 7 lb 9/3/2008 United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Congenital Anomaly Female 8 lb 9/3/2008 United Kingdom
Primary
Secondary
Talipes Congenital Anomaly Male 7 lb 9/3/2008 United Kingdom
Primary
Secondary
Hypospadias Congenital Anomaly Male 6 lb 9/3/2008 United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Congenital Anomaly Female 9/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Neonatal Disorder Congenital Anomaly Female 9/2/2008 United Kingdom
Primary
Secondary
Hip Dysplasia Congenital Anomaly Female 7 lb 9/10/2008 Physician United Kingdom
Primary
Secondary
Myoclonic Epilepsy Hospitalization 2 Female 9/3/2008 Physician Netherlands
Primary
Concomitant
Cleft Lip And Palate Congenital Anomaly Male 8 lb 9/18/2008 United Kingdom
Primary
Secondary
Spermatozoa Progressive Motility Decreased Other Serious Male 176 lb 9/19/2008 Consumer France
Primary
Concomitant
Vomiting 11/1/2006 Female 69 lb 10/8/2008 Physician United States
Primary
Secondary
Concomitant
Hydrocele Congenital Anomaly Female 10/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Talipes Congenital Anomaly Male 7 lb 10/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Talipes Congenital Anomaly Male 10/20/2008 United Kingdom
Primary
Secondary
Pregnancy With Implant Contraceptive 1/1/2007 36 Female 11/5/2008 Australia
Primary
Secondary
Concomitant
Pregnancy With Implant Contraceptive 1/1/2007 36 Female 11/7/2008 Australia
Primary
Secondary
Visual Acuity Reduced Disability 46 11/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 11/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2008 51 Female 12/8/2008 Consumer United States
Primary
Concomitant
Underdose 1/1/2006 Female 138 lb 12/12/2008 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Disability 46 12/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Visual Acuity Reduced Disability 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 26 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Petit Mal Epilepsy Other Serious Female 1/12/2009 Consumer Canada
Primary
Concomitant
Completed Suicide Death 1/1/2007 26 Male 1/15/2009 Other Health Professional Germany
Primary
Secondary
Rash Disability 6/1/2008 73 Female 1/13/2009 Physician United States
Primary
Concomitant
Petit Mal Epilepsy Other Serious 23 Female 1/26/2009 Consumer Canada
Primary
Concomitant
Completed Suicide Death 26 Male 1/21/2009 Physician United States
Primary
Secondary
Death Death 1/1/2007 26 Male 2/2/2009 Pharmacist United States
Primary
Secondary
Weight Decreased Other Serious 8/1/2008 51 Female 169 lb 2/17/2009 Consumer United States
Primary
Concomitant
Completed Suicide Death 26 Male 2/13/2009 Physician United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 3/10/2009 Other Health Professional Denmark
Primary
Secondary
Syndactyly Congenital Anomaly 6/5/1999 Male 8 lb 3/12/2009 United States
Primary
Secondary
Bipolar Disorder Hospitalization 3/2/2009 34 Female 190 lb 4/20/2009 Other Health Professional United States
Primary
Concomitant
Bipolar Disorder Hospitalization 3/2/2009 34 Female 190 lb 5/11/2009 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 5/3/2005 Female 121 lb 6/5/2009 Physician Australia
Primary
Concomitant
Choanal Atresia Congenital Anomaly Male 5 lb 6/5/2009 Physician Australia
Primary
Secondary
Lower Respiratory Tract Infection Other Serious Female 209 lb 6/10/2009 Physician Australia
Primary
Concomitant
Premature Baby Hospitalization Female 5 lb 6/10/2009 Physician Australia
Primary
Concomitant
Premature Baby Hospitalization 11/10/2005 Male 4 lb 6/12/2009 Physician Australia
Primary
Concomitant
Premature Baby Hospitalization Female 5 lb 6/12/2009 Physician Australia
Primary
Concomitant
Grand Mal Convulsion Hospitalization 4/12/2009 Male 154 lb 6/5/2009 Germany
Primary
Concomitant
Weight Decreased Other Serious 28 Female 6/16/2009 United Kingdom
Primary
Secondary
Weight Decreased Other Serious 28 Female 6/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Other Serious 28 Female 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Status Epilepticus Other Serious 5/28/2009 Female 6/24/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Retention Disability 4/1/2009 21 Female 7/21/2009 Consumer United Kingdom
Primary
Concomitant
Pneumonia Other Serious 19 Female 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Pneumonia Other Serious 2 Female 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Swelling Face Other Serious Female 8/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Speech Disorder Other Serious Male 8/17/2009 Consumer United Kingdom
Primary
Concomitant
Swelling Face Other Serious Female 8/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Required Intervention 6/1/2008 46 Female 8/13/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 28 Female 8/28/2009 United Kingdom
Primary
Secondary
Swelling Face Other Serious Female 8/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Unexplained Death In Epilepsy Death 15 Male 9/18/2009 Other Health Professional Brazil
Primary
Concomitant
Torticollis Congenital Anomaly 9/14/2009 Other Health Professional Denmark
Primary
Concomitant
Treatment Failure Other Serious 0 Male 9/21/2009
Primary
Secondary
Maternal Drugs Affecting Foetus Other Serious Female 9/18/2009 United Kingdom
Primary
Concomitant
Product Substitution Issue Other Serious 9/15/2009 Female 9/17/2009 Other Health Professional United States
Primary
Secondary
Simple Partial Seizures Other Serious 7/23/2009 Male 174 lb 9/30/2009 Consumer Portugal
Primary
Concomitant

Drug Data