Lamotrigine combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Partial Seizures With Secondary Generalisation Death 1/1/2006 Female 1/13/2006 Physician United Kingdom
Primary
Concomitant
Hypospadias Other Serious 1/19/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Rash 10/5/2005 58 Female 160 lb 1/5/2006 Consumer United States
Primary
Concomitant
Status Epilepticus Life Threatening 3/4/2005 Male 26 lb 3/24/2006 Physician Macedonia, The Former Yugoslav Republic Of
Primary
Secondary
Concomitant
Purpura Other Serious 46 Female 211 lb 4/14/2006 Other Health Professional United States
Primary
Concomitant
Purpura Other Serious 46 Female 211 lb 4/14/2006 Other Health Professional United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 23 Female 5/19/2006 Other Health Professional United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 23 Female 6/29/2006 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 23 Female 7/6/2006 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 7/27/2005 44 Female 8/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/27/2006 44 Female 8/29/2006 United States
Primary
Secondary
Concomitant
Uterine Contractions During Pregnancy Other Serious Female 9/29/2006 Pharmacist Germany
Primary
Concomitant
Anaemia Hospitalization 11/1/2005 43 Female 222 lb 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ectopic Pregnancy Other Serious 37 Female 10/10/2006 Other Health Professional United States
Primary
Concomitant
Osteoporotic Fracture Hospitalization 3/1/2006 29 Male 137 lb 8/18/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2004 21 Male 180 lb 8/18/2006 Physician United States
Primary
Concomitant
Petit Mal Epilepsy Other Serious 15 Male 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Other Serious 1/1/2005 17 Male 2/2/2007 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 106 lb 2/7/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 47 Male 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hyperhidrosis 12/6/2006 36 Male 175 lb 1/12/2007 Consumer United States
Primary
Concomitant
Ventricular Septal Defect Congenital Anomaly 5/22/2007 Other Health Professional United States
Primary
Concomitant
Polydactyly Congenital Anomaly Female 7 lb 5/30/2007 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/31/2007 Female 60 lb 6/20/2007 Physician Germany
Primary
Secondary
Concomitant
Somnolence Other Serious 2/1/2007 Female 6/29/2007 Pharmacist Canada
Primary
Concomitant
Premature Baby Hospitalization Female 7 lb 8/3/2007 Other Health Professional United States
Primary
Concomitant
Intraventricular Haemorrhage Neonatal Other Serious Male 5 lb 8/7/2007 Physician Serbia And Montenegro
Primary
Concomitant
Ventricular Septal Defect Other Serious Female 9/24/2007 Physician Belgium
Primary
Secondary
Visual Acuity Reduced Other Serious Male 159 lb 9/26/2007 Physician Germany
Primary
Concomitant
Visual Acuity Reduced Other Serious Male 159 lb 10/18/2007 Physician Germany
Primary
Concomitant
Uterine Infection Other Serious 34 Female 12/5/2007 Other Health Professional United States
Primary
Concomitant
Premature Baby Hospitalization Female 7 lb 12/5/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 45 Female 108 lb 1/30/2008 Consumer Brazil
Primary
Secondary
Concomitant
Vomiting Other Serious 40 Female 3/4/2008 Physician Brazil
Primary
Concomitant
Vomiting Other Serious 12 Female 3/4/2008 Physician Brazil
Primary
Concomitant
Joint Effusion Other Serious Male 172 lb 3/10/2008 Pharmacist United Kingdom
Primary
Concomitant
Visual Acuity Reduced Disability 46 4/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hip Dysplasia Congenital Anomaly 4/1/2002 7/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Talipes Congenital Anomaly 1/1/2005 7/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 7/10/2008 Physician Czech Republic
Primary
Secondary
Talipes Congenital Anomaly Male 7 lb 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Pyloric Stenosis Congenital Anomaly Male 5 lb 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Congenital Genital Malformation Male Congenital Anomaly Male 5 lb 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Hip Dysplasia Congenital Anomaly Male 5 lb 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Hypospadias Congenital Anomaly Male 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Abdominal Wall Anomaly Congenital Anomaly Female 8 lb 8/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Dysmorphism Congenital Anomaly Female 9 lb 8/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Pyloric Stenosis Other Serious 9/2/2008 Consumer United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Congenital Anomaly Male 6 lb 9/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Congenital Anomaly Male 6 lb 9/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Pyloric Stenosis Congenital Anomaly Male 5 lb 9/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Congenital Genital Malformation Male Congenital Anomaly Male 5 lb 9/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Hip Dysplasia Congenital Anomaly Male 5 lb 9/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Talipes Congenital Anomaly Male 7 lb 9/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Abdominal Wall Anomaly Congenital Anomaly Female 8 lb 9/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Dysmorphism Congenital Anomaly Female 9 lb 9/15/2008 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 3/1/2007 43 Male 9/15/2008 Consumer United States
Primary
Secondary
Concomitant
Cleft Lip And Palate Congenital Anomaly Male 8 lb 9/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Dysmorphism Congenital Anomaly Female 9/24/2008 Consumer United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Other Serious Male 9/22/2008 United Kingdom
Primary
Secondary
Grand Mal Convulsion Other Serious 7/2/2008 Male 231 lb 11/6/2008 Physician Germany
Primary
Concomitant
Visual Acuity Reduced Disability 46 11/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting 4/1/2008 Female 143 lb 12/2/2008 Consumer United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 12/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 12/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 12/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 12/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 46 12/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 8/1/2008 Female 77 lb 1/14/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Required Intervention 2/6/2009 44 Female 150 lb 2/26/2009 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious Male 9 lb 3/25/2009 Other Health Professional United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 38 Female 3/26/2009 Consumer United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 2/6/2009 38 Female 3/27/2009 Consumer United States
Primary
Secondary
Vision Blurred Required Intervention 11/1/2008 Female 4/22/2009 Other Health Professional United States
Primary
Concomitant
Product Substitution Issue Required Intervention 4/9/2009 Female 5/12/2009 Other Health Professional United States
Primary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly Female 5/27/2009 Other Health Professional United States
Primary
Concomitant
Small For Dates Baby Hospitalization 11/14/2004 Female 4 lb 6/5/2009 Physician Australia
Primary
Concomitant
Small For Dates Baby Hospitalization 11/14/2004 Male 5 lb 6/5/2009 Physician Australia
Primary
Concomitant
Somnolence Hospitalization Male 7 lb 6/9/2009 Physician Australia
Primary
Concomitant
Urine Uric Acid Other Serious Male 49 lb 6/15/2009 Physician Egypt
Primary
Concomitant
Suicidal Ideation Female 207 lb 6/25/2009 Other Health Professional United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 24 Female 7/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 4/20/2009 35 Female 7/16/2009 Consumer United States
Primary
Concomitant
Weight Gain Poor Other Serious 1/1/2006 15 Male 65 lb 8/19/2009 Physician Germany
Primary
Concomitant
Diabetes Mellitus Hospitalization 4/7/2003 38 Female 197 lb 9/23/2009 United States
Primary
Concomitant
Rash 9/2/2009 41 Female 177 lb 9/16/2009 United States
Primary
Concomitant
Tremor Hospitalization 36 Female 10/6/2009 Other Health Professional Canada
Primary
Concomitant
Intentional Overdose Life Threatening 10/14/2009 52 Female 10/20/2009 Consumer United States
Primary
Concomitant
Premature Baby Congenital Anomaly Female 7 lb 12/8/2009 Consumer United States
Primary
Concomitant
Urosepsis Other Serious 10/16/2009 24 Male 12/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rash 1/1/2008 73 Female 12/9/2009 Physician United States
Primary
Concomitant
Cleft Lip And Palate Other Serious Male 8 lb 12/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Hydrocele Congenital Anomaly Female 12/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Croup Infectious Hospitalization 49 Female 1/12/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 12 Male 1/13/2010 Consumer France
Primary
Concomitant
Talipes Congenital Anomaly 2/8/2010 Consumer United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Congenital Anomaly 2/8/2010 Consumer United Kingdom
Primary
Secondary
Suicide Attempt Hospitalization 35 Female 2/8/2010 Consumer United Kingdom
Primary
Concomitant
Vomiting In Pregnancy Other Serious 10/1/2009 34 Female 2/9/2010 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 35 Female 2/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 35 Female 2/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Glossitis 12/1/2008 47 Female 170 lb 2/26/2010 Consumer United States
Primary
Concomitant
Palpitations 11/1/2008 14 Female 2/26/2010 Consumer United States
Primary
Concomitant
Feeling Abnormal 3/1/2009 30 Female 2/26/2010 Consumer United States
Primary
Concomitant
Bipolar Disorder 1/1/2008 Female 2/26/2010 Consumer United States
Primary
Concomitant
Rash 47 Female 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Tinea Infection 4/29/2009 32 Male 2/26/2010 Consumer United States
Primary
Concomitant
Rash 8/4/2009 41 Female 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/5/2010 Female 140 lb 3/4/2010 Consumer United States
Primary
Secondary
Concomitant
Priapism Other Serious 3/1/2010 14 Male 4/5/2010 Physician Lebanon
Primary
Concomitant
Respiratory Distress Other Serious 42 Female 4/30/2010 Physician Germany
Primary
Concomitant
Nodule Other Serious 31 Female 6/2/2010 Physician Brazil
Primary
Concomitant
Drug Effect Decreased 4/1/2008 45 Male 182 lb 6/29/2010 Consumer United States
Primary
Concomitant
Sudden Death Death Female 7/13/2010 Physician Sweden
Primary
Secondary
Concomitant
Dysarthria Other Serious 14 Female 7/21/2010 Consumer United Kingdom
Primary
Secondary
Multi-organ Failure Life Threatening 7/27/2006 34 Male 163 lb 8/2/2010 Physician Germany
Primary
Concomitant
Drug Ineffective 5/1/2010 65 Female 8/5/2010 United States
Primary
Secondary
Dysarthria Other Serious 14 Female 8/11/2010 Consumer United Kingdom
Primary
Secondary
Drug Ineffective Other Serious 5/1/2010 65 Female 8/19/2010 United States
Primary
Secondary
Anaphylactic Reaction Life Threatening 12/1/2009 23 Female 8/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myalgia Male 278 lb 8/28/2010 United States
Primary
Concomitant
Oesophageal Ulcer Other Serious 7/1/2010 14 Female 9/1/2010 Pharmacist United Kingdom
Primary
Concomitant
Unevaluable Event 4/9/2009 42 Female 139 lb 9/9/2010 Consumer United States
Primary
Concomitant
Sudden Death Death Female 9/13/2010 Physician Sweden
Primary
Secondary
Concomitant
Vision Blurred 7/30/2009 62 Female 9/17/2010 Consumer United States
Primary
Concomitant
Sinusitis 25 Female 301 lb 9/20/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 38 Female 9/20/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 5/1/2010 14 Female 9/24/2010 Consumer United Kingdom
Primary
Secondary
Weight Increased Other Serious 9/1/2010 55 Male 165 lb 9/30/2010 Consumer United States
Primary
Concomitant
Convulsion Other Serious 21 Female 10/6/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 5/1/2010 14 Female 10/7/2010 Physician United Kingdom
Primary
Secondary
Vision Blurred Other Serious 5/1/2010 14 Female 10/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Vision Blurred Other Serious 5/1/2010 14 Female 10/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Vision Blurred Other Serious 5/1/2010 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Pancreatitis Hospitalization 8/3/2010 35 Female 333 lb 10/12/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 5/1/2010 14 Female 10/8/2010 United Kingdom
Primary
Secondary
Vision Blurred Other Serious 5/1/2010 14 Female 10/11/2010
Primary
Secondary
Multi-organ Failure Life Threatening 7/27/2006 34 Male 163 lb 10/20/2010 Physician Germany
Primary
Concomitant
Vision Blurred Other Serious 5/1/2010 14 Female 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Multi-organ Failure Life Threatening 7/27/2006 34 Male 163 lb 10/21/2010 Physician Germany
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 1/1/2005 15 Female 11/12/2010 Consumer United States
Primary
Interacting
Cleft Lip And Palate Congenital Anomaly 37 Male 8 lb 11/15/2010 Physician United Kingdom
Primary
Secondary
Weight Decreased Congenital Anomaly 21 Male 5 lb 11/15/2010 Physician United Kingdom
Primary
Secondary
Talipes Congenital Anomaly 27 Male 7 lb 11/15/2010 Physician United Kingdom
Primary
Secondary
Hip Dysplasia Congenital Anomaly Male 5 lb 11/15/2010 Physician United Kingdom
Primary
Secondary
Vision Blurred Other Serious 5/1/2010 14 Female 11/18/2010 Consumer United Kingdom
Primary
Secondary
Pyloric Stenosis Congenital Anomaly Male 5 lb 11/24/2010 Consumer United Kingdom
Primary
Secondary
Talipes Other Serious Male 7 lb 11/24/2010 Consumer United Kingdom
Primary
Secondary
Mental Disorder Hospitalization 45 Female 11/8/2010 United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 12/1/2010 Other Health Professional United States
Primary
Secondary

Drug Data