Lamotrigine combined with Sertraline

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased Hospitalization 11/7/2005 64 Male 144 lb 12/14/2005 Pharmacist United States
Primary
Concomitant
Neutropenia Other Serious 3/15/2006 38 Female 176 lb 4/11/2006 Physician Australia
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/15/2006 38 Female 176 lb 6/1/2006 Physician Australia
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 3/1/2006 17 Male 183 lb 6/13/2006 Physician United Kingdom
Primary
Concomitant
Multiple Drug Overdose Intentional Death 38 Female 9/14/2006 Physician United States
Primary
Secondary
Pulmonary Congestion Other Serious 38 Female 9/22/2006 Physician United States
Primary
Secondary
Completed Suicide Death 38 11/8/2006 Physician United States
Primary
Secondary
Substance Abuse Death 38 Unknown 11/15/2006 Physician United States
Primary
Secondary
Pulmonary Congestion Other Serious 1/1/2005 38 Female 11/21/2006 Physician United States
Primary
Secondary
Death Death 1/1/2005 41 11/22/2006 Physician United States
Primary
Secondary
Dysgeusia 1/1/2006 31 Female 140 lb 10/11/2006 United States
Primary
Concomitant
Status Epilepticus Life Threatening 12/26/2006 51 Male 1/8/2007 Pharmacist United States
Primary
Concomitant
Pain Other Serious 12/1/2006 60 Female 150 lb 3/6/2007 Physician Belgium
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 12/26/2006 51 Male 3/30/2007 Pharmacist United States
Primary
Concomitant
Epilepsy Other Serious 16 Male 3/27/2007 Other Health Professional Brazil
Primary
Concomitant
Thrombocytopenia Life Threatening 11/8/2006 Male 152 lb 4/20/2007 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 2/14/2007 9 Female 4/25/2007 Pharmacist United States
Primary
Concomitant
Thrombocythaemia Other Serious 47 Female 5/21/2007 Consumer Brazil
Primary
Concomitant
Transplant 3/23/2007 65 Male 5/29/2007 United States
Primary
Concomitant
Skin Odour Abnormal 10/16/2007 Male 255 lb 12/14/2007 Consumer United States
Primary
Concomitant
Myalgia Other Serious 8/1/2007 40 Female 12/19/2007 Consumer United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 37 Female 1/10/2008 Canada
Primary
Secondary
Concomitant
Drug Interaction Other Serious Male 3/14/2008 Other Health Professional United Kingdom
Primary
Interacting
Pharyngolaryngeal Pain 12/11/2007 Female 124 lb 3/14/2008
Primary
Concomitant
Neonatal Hypoxia Other Serious Female 3/28/2008 Physician Hungary
Primary
Concomitant
Drug Interaction Other Serious Male 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Drug Interaction Other Serious Male 4/4/2008 Physician United Kingdom
Primary
Interacting
Drug Interaction Other Serious Male 4/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Drug Interaction Other Serious Male 4/7/2008 United Kingdom
Primary
Secondary
Drug Interaction Other Serious Male 4/9/2008 Physician United Kingdom
Primary
Secondary
Pyrexia 4/24/2008 Female 137 lb 6/13/2008 United States
Primary
Concomitant
Contusion 5/1/2008 Female 6/13/2008 United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 53 Female 7/15/2008 Consumer Hungary
Primary
Secondary
Concomitant
Neonatal Hypoxia Other Serious Female 7/22/2008 Physician Hungary
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 53 Female 8/1/2008 Hungary
Primary
Secondary
Concomitant
Pruritus 5/1/2008 Female 222 lb 8/29/2008 Consumer United States
Primary
Concomitant
Blood Triglycerides Abnormal Male 152 lb 9/2/2008 Consumer United States
Primary
Concomitant
Vascular Calcification Other Serious 1/1/2006 41 Female 165 lb 9/12/2008 Consumer Brazil
Primary
Concomitant
Drug Ineffective 8/1/2007 Female 240 lb 9/12/2008 United States
Primary
Concomitant
Pain 4/25/2008 Female 9/12/2008 United States
Primary
Secondary
Concomitant
Injection Site Swelling Male 9/12/2008
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 10/1/2008 19 Female 137 lb 11/20/2008 United States
Primary
Secondary
Concomitant
Tachypnoea Other Serious 10/5/2008 Female 225 lb 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 18 Female 12/31/2008 Pharmacist United States
Primary
Secondary
Intentional Drug Misuse Death 1/1/2007 18 Female 1/6/2009 United States
Primary
Secondary
Tachypnoea Other Serious 47 Female 1/9/2009 United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 18 Female 1/15/2009 United States
Primary
Secondary
Urticaria Other Serious 11/25/2008 19 Female 101 lb 1/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Poisoning Death 18 Female 1/16/2009 Physician United States
Primary
Secondary
Poisoning Deliberate Death 18 Female 1/26/2009 Physician United States
Primary
Secondary
Tardive Dyskinesia Other Serious 43 Female 3/20/2009
Primary
Secondary
Concomitant
Suicide Attempt Life Threatening 5/8/2009 17 Male 150 lb 5/12/2009 Physician United States
Primary
Secondary
Skin Ulcer Other Serious 4/15/2009 33 Female 182 lb 6/15/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Necrotising Other Serious 1/11/2009 56 Female 6/26/2009 United Kingdom
Primary
Concomitant
Pancreatitis Necrotising Other Serious 1/1/2009 56 Female 157 lb 7/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Necrotising Other Serious 1/1/2009 56 Female 157 lb 7/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Stomatitis Other Serious 62 Female 7/16/2009 Consumer Germany
Primary
Secondary
Pancreatitis Necrotising Required Intervention 1/11/2009 56 Female 157 lb 7/10/2009
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 62 Female 161 lb 8/10/2009 Other Health Professional Germany
Primary
Secondary
Stevens-johnson Syndrome Life Threatening 62 Female 161 lb 8/5/2009 Other Health Professional Germany
Primary
Secondary
Skin Burning Sensation 11/4/2008 Male 8/22/2009 United States
Primary
Concomitant
Transaminases Increased Other Serious 1/1/2009 38 Female 11/11/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Respiratory Arrest Death 21 Female 1/8/2010 Other Health Professional United States
Primary
Secondary
Transaminases Increased Other Serious 1/1/2009 38 Female 1/28/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious Female 7/9/2010 Physician Germany
Primary
Concomitant
Transaminases Increased Other Serious 1/1/2009 38 Female 8/23/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 1/1/2009 38 Female 9/16/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/1/2010 55 Male 165 lb 9/30/2010 Consumer United States
Primary
Concomitant
Transaminases Increased Other Serious 1/1/2009 38 Female 8/23/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Completed Suicide Death 59 Female 1/7/2011 Physician United States
Primary
Secondary
Drug Ineffective 12/22/2010 54 Male 1/14/2011 Consumer
Primary
Concomitant
Completed Suicide Death 59 Female 1/14/2011 Other Health Professional
Primary
Secondary
Urinary Tract Infection Hospitalization 7/15/2010 74 Male 1/20/2011 Pharmacist Ireland
Primary
Concomitant
Toxicity To Various Agents Death 20 Male 1/20/2011 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 59 Female 1/21/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 59 Female 1/14/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 20 Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Poisoning Death 1/1/2009 59 Female 1/24/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2009 59 Female 1/25/2011 Physician United States
Primary
Secondary
Multiple Drug Overdose Intentional Death 59 Female 2/5/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2009 59 Female 2/24/2011 Physician United States
Primary
Secondary
Drug Ineffective 12/22/2010 54 Male 3/2/2011 Consumer United States
Primary
Concomitant
Hepatotoxicity Other Serious 48 Male 3/4/2011 Physician Chile
Primary
Secondary
Completed Suicide Death 59 Female 3/7/2011 Physician United States
Primary
Secondary
Cholestasis Other Serious 48 Male 4/13/2011 Physician Chile
Primary
Secondary
Cholesterosis Other Serious 6/1/2008 36 Female 4/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Cholecystectomy Other Serious 6/1/2008 36 Female 4/18/2011 Consumer United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 53 Female 4/22/2011 Consumer United States
Primary
Secondary
Toxicity To Various Agents Death 53 Female 4/26/2011 Other Health Professional United States
Primary
Secondary
Alcohol Poisoning Death 53 Female 4/29/2011 Consumer United States
Primary
Secondary
Toxicity To Various Agents Death 53 Female 5/4/2011 Consumer United States
Primary
Secondary
Suicide Attempt Life Threatening 10/4/2010 34 Female 253 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Petit Mal Epilepsy Other Serious 6/15/2011 6/30/2011 Pharmacist Germany
Primary
Concomitant
Abdominal Distension Other Serious 10/1/2011 39 Female 201 lb 10/27/2011 Consumer Brazil
Primary
Concomitant
Constipation Other Serious 10/1/2011 39 Female 201 lb 11/1/2011 Consumer Brazil
Primary
Concomitant
Abdominal Pain Other Serious 10/1/2011 39 Female 201 lb 11/10/2011 Physician Brazil
Primary
Concomitant
Memory Impairment Other Serious 1/1/2012 52 Male 249 lb 2/2/2012 Consumer United States
Primary
Concomitant
Interacting
Vein Pain Other Serious 1/1/2012 49 Female 115 lb 7/2/2012 Consumer Brazil
Primary
Concomitant
Toxicity To Various Agents Hospitalization 4/24/2012 71 Male 161 lb 4/26/2012 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/31/2009 47 Female 8/23/2013 Pharmacist Gb
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/11/2009 30 Female 372 lb 9/13/2012 Consumer Us
Primary
Secondary
Concomitant
Cerebrovascular Accident Death Female 178 lb 10/23/2012 Physician Country Not Specified
Primary
Concomitant
Vomiting 6/12/2012 56 Female 9/6/2012 Consumer Us
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 36 Female 8/29/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 5/2012 Female 9/21/2012 Pharmacist Us
Primary
Secondary
Vomiting Other Serious 2012 Male 270 lb 11/8/2012 Other Health Professional Us
Primary
Concomitant
Completed Suicide Death 2005 38 9/28/2012 Other Health Professional Country Not Specified
Primary
Secondary
Death Death 2005 41 9/28/2012 Other Health Professional Country Not Specified
Primary
Secondary
Intestinal Obstruction Hospitalization 5/2012 Female 9/26/2012 Pharmacist Us
Primary
Secondary
Tachycardia Hospitalization 8/16/2012 42 Female 9/30/2012 Physician Gb
Primary
Secondary
Concomitant
Drug Interaction Other Serious 33 Female 10/9/2012 Physician Us
Primary
Concomitant
Interacting
Toxicity To Various Agents Other Serious 10/19/2012 Physician Us
Primary
Concomitant
Interacting
Intentional Drug Misuse Other Serious 33 Female 11/14/2012 Physician Us
Primary
Secondary
Weight Increased Other Serious 33 Female 12/6/2012 Other Health Professional Country Not Specified
Primary
Secondary
Ocular Hyperaemia 10/2012 58 Female 12/13/2012 Physician Country Not Specified
Primary
Concomitant
Circulatory Collapse Life Threatening 12/17/2012 34 Female 1/8/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Atrioventricular Block Hospitalization 12/17/2012 34 Female 1/10/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Atrioventricular Block Hospitalization 12/17/2012 34 Female 1/15/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Rash Other Serious 2010 57 Female 200 lb 1/25/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Vomiting 8/9/2012 53 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Local Swelling 7/17/2012 52 Female 1/31/2013 Physician Country Not Specified
Primary
Concomitant
Fatigue Other Serious 34 Female 2/14/2013 Other Health Professional De
Primary
Concomitant
Interacting
Vomiting 2012 35 Female 123 lb 2/27/2013 Consumer Us
Primary
Concomitant
Malaise 8/10/2012 59 Female 2/27/2013 Consumer Us
Primary
Concomitant
Syncope Hospitalization 12/17/2012 34 Female 1/6/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Drug Dose Omission 3/6/2013 54 Male 4/5/2013 Pharmacist Us
Primary
Concomitant
Somnolence Other Serious 84 Male 4/24/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/16/2013 23 Female 4/29/2013 Consumer Se
Primary
Secondary
Parkinsonism Other Serious 84 Male 5/15/2013 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 3/3/2013 47 Male 8/15/2013 Physician Us
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Hospitalization 11/10/2012 19 Female 6/13/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Restlessness Other Serious 24 Male 7/11/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Weight Increased Other Serious 24 Male 6/25/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Leukopenia Other Serious 9/12/2012 62 Male 6/27/2013 Pharmacist Us
Primary
Concomitant
Granulocytopenia Other Serious 8/1/2012 25 Female 6/27/2013 Pharmacist Us
Primary
Concomitant
Skin Disorder Other Serious 6/9/2013 44 Female 218 lb 6/27/2013 Other Health Professional Gb
Primary
Concomitant
Skin Disorder Other Serious 6/9/2013 44 Female 218 lb 7/5/2013 Other Health Professional Gb
Primary
Concomitant
Weight Increased Other Serious 0 Male 185 lb 7/8/2013 Other Health Professional Country Not Specified
Primary
Secondary
Weight Increased Other Serious 0 Male 185 lb 7/8/2013 Other Health Professional Country Not Specified
Primary
Secondary
Neuroleptic Malignant Syndrome Other Serious 54 Male 7/6/2013 Physician Jp
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 18 Female 7/19/2013 Other Health Professional Se
Primary
Secondary
Death Death 7/18/2013 43 Male 9/24/2013 Other Health Professional Us
Primary
Secondary
Neuroleptic Malignant Syndrome Other Serious 54 Male 8/16/2013 Physician Jp
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 54 Male 8/25/2013 Physician Jp
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 54 Male 8/25/2013 Physician Jp
Primary
Concomitant
Therapeutic Response Unexpected Male 205 lb 8/28/2013 Consumer Us
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious NotSpecified 9/4/2013 Physician Jp
Primary
Concomitant
Tremor Other Serious 54 Male 8/22/2013 Other Health Professional Jp
Primary
Concomitant
Neonatal Respiratory Distress Syndrome Hospitalization 9/9/2013 1 Female 7 lb 9/20/2013 Other Health Professional Au
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 76 Male 9/11/2013 Other Health Professional Jp
Primary
Concomitant

Drug Data