Lamotrigine combined with Lorazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Rash Vesicular 4/5/2004 82 Female 2/28/2006 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 7/3/2005 Female 195 lb 3/3/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 2/23/2005 56 Female 208 lb 4/4/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 11/15/2005 48 Female 88 lb 2/24/2006 United States
Primary
Concomitant
Sudden Cardiac Death Hospitalization 11/25/2005 69 Female 11/21/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Somnolence Hospitalization 9/12/2006 74 Male 209 lb 12/6/2006 Other Health Professional France
Primary
Concomitant
Somnolence Other Serious Female 1/4/2007 Consumer Ireland
Primary
Secondary
Posture Abnormal Other Serious 52 Female 1/19/2007 Other Health Professional Spain
Primary
Secondary
Weight Increased Other Serious 1/1/2001 Female 350 lb 10/10/2006 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2007 63 Female 2/1/2007 Pharmacist Canada
Primary
Concomitant
Serotonin Syndrome Hospitalization 10/1/2006 51 Female 228 lb 2/14/2007 Physician United States
Primary
Concomitant
Poisoning Deliberate Other Serious 0 Male 2/19/2007 Consumer United Kingdom
Primary
Secondary
Serotonin Syndrome Hospitalization 10/1/2006 51 Female 224 lb 4/23/2007 Physician United States
Primary
Concomitant
Dysphasia Hospitalization 2/28/2007 Female 5/7/2007 Physician France
Primary
Concomitant
Rash Other Serious 9/20/2006 10 Male 61 lb 3/5/2007 Other Health Professional United States
Primary
Concomitant
Poisoning Deliberate Other Serious 0 Male 5/31/2007 Consumer United Kingdom
Primary
Secondary
Medication Error Hospitalization 3/29/2007 Male 7/6/2007 United States
Primary
Secondary
Concomitant
Premature Baby Hospitalization Female 7 lb 8/3/2007 Other Health Professional United States
Primary
Concomitant
Dizziness 6/28/2007 70 Female 123 lb 10/5/2007 Consumer United States
Primary
Concomitant
Insomnia 42 Female 119 lb 10/5/2007 Consumer United States
Primary
Secondary
Concomitant
Hallucination, Visual Hospitalization 6/26/2007 65 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Uterine Infection Other Serious 34 Female 12/5/2007 Other Health Professional United States
Primary
Concomitant
Premature Baby Hospitalization Female 7 lb 12/5/2007 Other Health Professional United States
Primary
Concomitant
Epistaxis 5/10/2007 21 Male 170 lb 5/10/2007 Pharmacist United States
Primary
Concomitant
Suicide Attempt Hospitalization 12/31/2007 Male 1/14/2008 Other Health Professional Germany
Primary
Secondary
Thinking Abnormal Hospitalization 4/24/2005 51 Male 206 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 1/1/2008 37 Female 231 lb 2/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 35 Male 1/28/2008 Physician Germany
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 12/31/2007 Male 2/6/2008 Other Health Professional Germany
Primary
Secondary
Rhabdomyolysis Life Threatening 1/1/2008 37 Female 231 lb 2/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Status Epilepticus Life Threatening 1/1/2008 37 Female 231 lb 2/19/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/20/2008 Female 2/22/2008 Other Health Professional Germany
Primary
Secondary
Rhabdomyolysis Life Threatening 1/1/2008 37 Female 231 lb 3/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Hospitalization 81 Female 3/4/2008 United States
Primary
Concomitant
Convulsion Other Serious 4/12/2008 50 Female 4/16/2008 Physician United States
Primary
Concomitant
Suicide Attempt Other Serious 62 Male 4/24/2008 Consumer Germany
Primary
Concomitant
Convulsion Other Serious 4/12/2008 Female 191 lb 6/6/2008 Physician United States
Primary
Concomitant
Drug Eruption Hospitalization 12/1/2007 36 Male 187 lb 6/3/2008 Physician Switzerland
Primary
Concomitant
Malaise Other Serious Male 6/25/2008 Physician United Kingdom
Primary
Concomitant
Pickwickian Syndrome Death 4/15/2008 Male 7/21/2008 Physician United States
Primary
Concomitant
Thinking Abnormal Life Threatening 1/1/2002 Male 215 lb 7/31/2008 Consumer United States
Primary
Secondary
Concomitant
Thinking Abnormal Life Threatening 1/1/2002 Male 215 lb 8/1/2008 Consumer United States
Primary
Secondary
Concomitant
Pruritus 5/1/2008 Female 222 lb 8/29/2008 Consumer United States
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 75 Male 8/27/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 52 Male 9/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thinking Abnormal Life Threatening 1/1/2002 Male 215 lb 9/15/2008 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 7/31/2008 Female 9/17/2008 Physician United Kingdom
Primary
Concomitant
Hepatotoxicity Other Serious 4 9/23/2008 Consumer United States
Primary
Secondary
Concomitant
Delirium Hospitalization 41 Female 9/23/2008 Physician United States
Primary
Secondary
White Blood Cell Count Increased Other Serious Female 143 lb 11/4/2008 Consumer Argentina
Primary
Concomitant
White Blood Cell Count Increased Other Serious Female 143 lb 11/30/2008 Consumer Argentina
Primary
Concomitant
Syncope Hospitalization 11/16/2008 Female 160 lb 12/16/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/16/2008 Consumer Argentina
Primary
Concomitant
Priapism Other Serious 3/1/2008 40 Male 12/18/2008 Physician Chile
Primary
Concomitant
Drug Toxicity Death 56 Female 12/24/2008 Physician United States
Primary
Secondary
Completed Suicide Death 44 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 56 Female 12/31/2008 Pharmacist United States
Primary
Secondary
Drug Toxicity Death 44 Male 1/5/2009 Other Health Professional United States
Primary
Secondary
Multiple Drug Overdose Intentional Death 56 Female 1/7/2009 United States
Primary
Secondary
Completed Suicide Death 1/1/2007 56 Female 1/15/2009 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 56 Female 1/15/2009 Physician United States
Primary
Secondary
Poisoning Death Male 1/15/2009 Physician United States
Primary
Secondary
Status Epilepticus Other Serious 11/21/2008 15 Female 1/15/2009 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Death 44 Male 1/26/2009 Other Health Professional United States
Primary
Secondary
Multiple Drug Overdose Intentional Death 56 Female 1/21/2009 Physician United States
Primary
Secondary
Completed Suicide Death 44 Male 1/21/2009 Physician United States
Primary
Secondary
Completed Suicide Death 56 Female 1/21/2009 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/30/2009 Other Health Professional United States
Primary
Secondary
Priapism Other Serious 3/1/2008 40 Male 2/5/2009 Other Health Professional Chile
Primary
Concomitant
Death Death 1/1/2007 56 Female 2/4/2009 Pharmacist United States
Primary
Secondary
Transaminases Increased Other Serious 53 Male 2/20/2009
Primary
Secondary
Respiratory Arrest Death 56 Female 2/27/2009 Physician United States
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 42 Female 3/9/2009 Other Health Professional Germany
Primary
Secondary
Hallucination Other Serious 5/1/2006 60 Male 3/11/2009 France
Primary
Interacting
Convulsion Other Serious Female 150 lb 3/12/2009 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2008 44 Female 3/16/2009 Physician Israel
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2008 44 Female 3/17/2009 Physician Israel
Primary
Concomitant
Hallucination Other Serious 5/1/2006 60 Male 3/26/2009 France
Primary
Interacting
Panic Reaction Other Serious 5/1/2006 Male 3/27/2009 Consumer Germany
Primary
Concomitant
Completed Suicide Death 44 Male 3/31/2009 Physician United States
Primary
Secondary
Dysmenorrhoea 10/1/2008 Female 4/2/2009 Other Health Professional United States
Primary
Concomitant
Erythema Nodosum Other Serious 1/1/2007 Female 4/6/2009 Physician United States
Primary
Concomitant
Headache Other Serious 3/20/2009 Male 3/24/2009 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 10/7/2008 50 Male 233 lb 2/25/2009 Physician United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 39 Female 4/22/2009 Other Health Professional United States
Primary
Concomitant
Turner's Syndrome Congenital Anomaly 4/22/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 4/23/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 4/29/2009 Other Health Professional United States
Primary
Concomitant
Completed Suicide Other Serious 5/1/2009 Other Health Professional United States
Primary
Secondary
Product Substitution Issue Required Intervention 8/1/2008 Female 5/7/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Life Threatening 1/1/2008 44 Female 5/13/2009 Physician Israel
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 5/13/2009 Other Health Professional United States
Primary
Concomitant
Subdural Haematoma Other Serious 7/1/2005 59 Male 5/14/2009
Primary
Secondary
Respiratory Failure Other Serious 4/5/2009 Male 183 lb 5/25/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 4/5/2009 Male 183 lb 6/8/2009 Other Health Professional United States
Primary
Concomitant
Peritoneal Dialysis Hospitalization Male 152 lb 6/5/2009 Other Health Professional United States
Primary
Concomitant
Sudden Death Other Serious 1/1/2007 33 Male 6/12/2009 Physician Canada
Primary
Concomitant
Weight Increased Life Threatening 1/1/2008 44 Female 6/24/2009 Physician Israel
Primary
Concomitant
Skin Warm 6/21/2009 34 Female 221 lb 6/24/2009 Other Health Professional United States
Primary
Concomitant
Purpura Other Serious 6/7/2009 48 Male 7/6/2009 Germany
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 1/28/2009 Male 6/23/2009 United States
Primary
Concomitant
Restless Legs Syndrome Other Serious 7/1/2009 Female 8/4/2009 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2004 35 Female 8/6/2009 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 6/29/2009 Male 189 lb 8/18/2009 United States
Primary
Secondary
Concomitant
Thinking Abnormal Other Serious 7/6/2005 51 Male 181 lb 8/20/2009 United States
Primary
Concomitant
Restless Legs Syndrome Other Serious 7/1/2009 36 Female 8/21/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 Male 129 lb 9/16/2009 United States
Primary
Concomitant
Restless Legs Syndrome Other Serious 7/1/2009 36 Female 9/23/2009 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 34 10/1/2009
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 1/1/2005 35 Female 235 lb 10/14/2009 United States
Primary
Concomitant
Vomiting Hospitalization 8/25/2009 48 Female 10/22/2009 Pharmacist United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 34 11/5/2009 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 5/6/2009 57 Female 11/17/2009 Consumer Germany
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 5/6/2009 57 Female 11/20/2009 Consumer Germany
Primary
Secondary
Concomitant
Hyperreflexia Other Serious 57 Female 11/16/2009 Physician Germany
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 34 11/10/2009 Other Health Professional United States
Primary
Concomitant
Withdrawal Syndrome Required Intervention 34 11/20/2009 United States
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 75 Male 11/30/2009 Physician United States
Primary
Secondary
Concomitant
Extensor Plantar Response Hospitalization 5/6/2009 57 Female 11/24/2009 Physician
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/8/2009 Female 161 lb 12/11/2009 United States
Primary
Concomitant
Speech Disorder Hospitalization 10/10/2009 Male 251 lb 10/12/2009 United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 1/1/2009 40 Female 12/18/2009 Physician Spain
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 43 Male 1/8/2010 Physician Austria
Primary
Secondary
Concomitant
Completed Suicide Death 49 Female 1/19/2010 United States
Primary
Secondary
Concomitant
Completed Suicide Death 21 Female 1/20/2010 United States
Primary
Secondary
Concomitant
Completed Suicide Death 50 Male 1/18/2010 United States
Primary
Secondary
Concomitant
Convulsion Other Serious 1/27/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 43 Male 1/26/2010 Austria
Primary
Secondary
Concomitant
Swelling Face Hospitalization 1/16/2010 75 Female 102 lb 2/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 12/30/2005 41 Male 154 lb 2/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Depression Hospitalization 10/3/2009 Female 143 lb 2/12/2010 Physician United States
Primary
Concomitant
Pyrexia Other Serious 12/30/2005 41 Male 154 lb 2/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/16/2010 75 Female 102 lb 2/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/16/2010 75 Female 102 lb 2/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/8/2009 Female 161 lb 2/24/2010 United States
Primary
Concomitant
Vomiting Female 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Insomnia 57 Female 2/26/2010 Consumer United States
Primary
Concomitant
Troponin Increased 4/13/2009 72 Male 160 lb 4/21/2009 Pharmacist United States
Primary
Concomitant
Death Death 1/1/2008 29 Male 2/23/2010 Physician United States
Primary
Concomitant
Swelling Face Hospitalization 1/16/2010 75 Female 102 lb 3/2/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 6/1/2009 Female 3/2/2010 Physician United Kingdom
Primary
Concomitant
Death Death 29 Male 3/5/2010 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Hospitalization 12/28/2009 66 Male 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Hepatic Failure Other Serious 1/17/2010 57 Male 195 lb 3/25/2010 Pharmacist Canada
Primary
Concomitant
Pyrexia Other Serious 7/31/2008 47 Female 3/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Other Serious Male 4/5/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased 19 Male 4/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/28/2009 66 Male 4/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 43 Male 5/25/2010 Other Health Professional Austria
Primary
Secondary
Concomitant

Drug Data