Lamotrigine combined with Levothyroxine Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Somnolence Other Serious 36 Male 2/15/2006 United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Other Serious 7/3/2005 Female 195 lb 3/3/2006 Physician United States
Primary
Concomitant
Urticaria Disability 1/1/2004 Female 140 lb 3/7/2006 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/23/2005 56 Female 208 lb 4/4/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 12/18/2005 71 Male 3/13/2006 Physician United States
Primary
Concomitant
Insomnia 53 Female 170 lb 4/3/2006 Consumer United States
Primary
Concomitant
Intention Tremor Hospitalization Female 6/22/2006 Pharmacist France
Primary
Concomitant
Intention Tremor Hospitalization 57 Female 6/30/2006 Pharmacist France
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 12/31/2005 Female 152 lb 6/26/2006 Pharmacist United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 10/31/2005 40 Male 2/6/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 6/12/2006 17 Female 259 lb 8/9/2006 Pharmacist United States
Primary
Concomitant
Leukopenia Required Intervention 1/31/2006 36 Male 4/19/2006 Consumer United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 54 Female 8/29/2006 United Kingdom
Primary
Secondary
Concomitant
Cholestasis Other Serious 9/1/2006 Female 10/18/2006 Physician France
Primary
Concomitant
Sudden Cardiac Death Hospitalization 11/25/2005 69 Female 11/21/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Parathyroid Tumour Benign Other Serious 1/1/1995 45 Female 11/23/2006 Physician United States
Primary
Concomitant
Urine Ketone Body Present Other Serious 12/1/2005 Female 12/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Intentional Overdose Other Serious 65 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Weight Increased Other Serious 1/1/2001 Female 350 lb 10/10/2006 Consumer United States
Primary
Concomitant
Mania Other Serious 12/29/2006 69 Female 1/29/2007 Physician United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 2/4/2006 69 Female 140 lb 1/29/2007 Physician United Kingdom
Primary
Concomitant
Drug Ineffective Female 11/21/2006 United States
Primary
Concomitant
Unevaluable Event Other Serious 11/5/2006 Male 156 lb 2/12/2007 Physician France
Primary
Concomitant
Renal Impairment Other Serious 69 Female 140 lb 2/5/2007 Physician United Kingdom
Primary
Concomitant
Medication Error 3/14/2007 Pharmacist United States
Primary
Secondary
Suicidal Ideation Hospitalization 35 Female 5/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neoplasm Recurrence Other Serious 3/27/2007 47 Female 5/14/2007 United Kingdom
Primary
Concomitant
Skin Exfoliation Other Serious 5/10/2007 52 Female 5/25/2007 Physician Argentina
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 35 Female 6/1/2007 United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 8/3/2007 36 Female 116 lb 9/4/2007 Consumer United States
Primary
Concomitant
Hypersensitivity Hospitalization 8/3/2007 36 Female 116 lb 9/4/2007 Consumer United States
Primary
Concomitant
Pelvic Venous Thrombosis Life Threatening 9/13/2007 Female 209 lb 9/27/2007 Germany
Primary
Secondary
Concomitant
Pelvic Venous Thrombosis Life Threatening 9/13/2007 Female 209 lb 10/2/2007 Germany
Primary
Secondary
Concomitant
Pelvic Venous Thrombosis Life Threatening 9/10/2007 Female 209 lb 10/8/2007 Germany
Primary
Secondary
Concomitant
Pelvic Venous Thrombosis Life Threatening 9/10/2007 Female 209 lb 10/23/2007 Germany
Primary
Secondary
Concomitant
Tremor Other Serious 10/9/2007 Female 11/16/2007 Pharmacist United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 10/24/2007 53 Female 11/19/2007 Consumer United Kingdom
Primary
Concomitant
Paraesthesia Oral Other Serious 10/26/2006 53 Female 103 lb 11/17/2007 Physician Canada
Primary
Concomitant
Weight Increased Other Serious 49 Female 11/27/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 10/9/2007 Female 11/28/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Tremor Other Serious 10/9/2007 Female 12/7/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Urethral Cancer Metastatic Other Serious 66 Male 12/14/2007 Physician Canada
Primary
Concomitant
Rash Generalised Other Serious 10/23/2007 67 Female 12/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urethral Cancer Metastatic Death 5/7/2007 65 Male 12/18/2007 Physician Canada
Primary
Concomitant
Dystonia Other Serious 61 Female 1/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stomach Discomfort Other Serious 8/7/2007 37 Female 122 lb 12/11/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 46 Female 1/31/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/14/2007 56 Female 154 lb 1/28/2008 Physician Austria
Primary
Concomitant
Neoplasm Recurrence Other Serious 7/12/2005 Male 19 lb 3/5/2008 France
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Hospitalization 81 Female 3/4/2008 United States
Primary
Concomitant
Vomiting Hospitalization 3/26/2008 35 Female 132 lb 4/1/2008 Pharmacist United States
Primary
Concomitant
Vision Blurred 7/1/2007 Female 182 lb 4/11/2008 Consumer United States
Primary
Concomitant
Convulsion Other Serious 4/12/2008 50 Female 4/16/2008 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 5/1/2001 Female 4/22/2008 Physician United Kingdom
Primary
Concomitant
Sensory Loss Hospitalization 3/10/2008 Male 448 lb 4/29/2008 Consumer United Kingdom
Primary
Concomitant
Meningitis Aseptic Hospitalization 36 Female 5/9/2008 United States
Primary
Secondary
Concomitant
Convulsion Other Serious 4/12/2008 Female 191 lb 6/6/2008 Physician United States
Primary
Concomitant
Dysarthria Other Serious 5/21/2008 60 Male 205 lb 6/9/2008 Consumer United States
Primary
Concomitant
Oligohydramnios Other Serious 7/23/2007 Female 7/9/2008 Consumer France
Primary
Concomitant
Uterine Leiomyoma Hospitalization 1/1/2008 39 Female 8/5/2008 Chile
Primary
Concomitant
Liver Function Test Abnormal Other Serious 5/7/2008 58 Female 141 lb 8/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Immobile Other Serious 11/15/2007 Female 8/15/2008 Physician France
Primary
Concomitant
Dystonia Other Serious 12/1/2007 61 Female 8/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus 5/1/2008 Female 222 lb 8/29/2008 Consumer United States
Primary
Concomitant
Headache Female 8/29/2008 United States
Primary
Concomitant
Blood Triglycerides Abnormal Male 152 lb 9/2/2008 Consumer United States
Primary
Concomitant
Visual Field Defect Other Serious 6/1/2008 Female 10/7/2008 Physician United States
Primary
Secondary
Concomitant
Interacting
Therapeutic Response Unexpected With Drug Substitution Hospitalization 10/29/2008 32 Female 130 lb 11/9/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2008 51 Female 12/8/2008 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 11/21/2008 Female 210 lb 12/12/2008 Consumer United States
Primary
Concomitant
Limb Malformation Congenital Anomaly 10/3/2008 32 12/19/2008 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2008 48 Male 205 lb 12/19/2008 Pharmacist United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2007 37 Male 1/15/2009 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 37 Male 1/16/2009 United States
Primary
Secondary
Rash Disability 6/1/2008 73 Female 1/13/2009 Physician United States
Primary
Concomitant
Respiratory Arrest Death 37 Male 1/19/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 37 Male 1/19/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 37 Male 1/22/2009 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2007 37 Male 2/3/2009 Pharmacist United States
Primary
Secondary
Multiple Sclerosis Other Serious 1/1/2008 60 Female 125 lb 2/2/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2008 51 Female 169 lb 2/17/2009 Consumer United States
Primary
Concomitant
Benign Hepatic Neoplasm 1/1/1994 Female 190 lb 3/12/2009 Consumer United States
Primary
Concomitant
Sudden Unexplained Death In Epilepsy Death 3/9/2009 Female 3/23/2009 Germany
Primary
Concomitant
Somnolence Life Threatening 11/10/2008 52 Male 234 lb 3/16/2009 Other Health Professional United States
Primary
Concomitant
Tachyphrenia Hospitalization 7/1/2008 47 Male 3/16/2009 United States
Primary
Secondary
Concomitant
Dyskinesia Other Serious 1/26/2009 14 Male 4/4/2009 Canada
Primary
Concomitant
Vulvovaginal Candidiasis Hospitalization 1/19/2001 33 Female 295 lb 4/15/2009 Other Health Professional United States
Primary
Concomitant
Tonic Convulsion Other Serious 54 Female 4/7/2009 United Kingdom
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 54 Female 4/7/2009 United States
Primary
Secondary
Concomitant
Delirium Hospitalization 12/2/2008 58 Female 4/23/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Epilepsy Other Serious 1/1/2008 83 Female 4/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Product Substitution Issue Other Serious 1/1/2008 83 Female 5/5/2009 United Kingdom
Primary
Secondary
Concomitant
Epilepsy Other Serious 1/1/2008 83 Female 5/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Epilepsy Hospitalization 1/1/2008 83 Female 5/21/2009 United Kingdom
Primary
Secondary
Concomitant
Epilepsy Other Serious 1/1/2008 83 Female 6/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Product Substitution Issue Hospitalization 1/1/2008 83 Female 6/8/2009 United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 50 Female 6/19/2009 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 50 Female 7/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Meningitis Aseptic Hospitalization 50 Female 7/15/2009 United States
Primary
Concomitant
Suicidal Ideation Hospitalization 50 Female 7/15/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 50 Female 7/16/2009 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 50 Female 7/27/2009
Primary
Secondary
Concomitant
Feeling Hot 6/1/2009 Female 8/22/2009 United States
Primary
Concomitant
Dyskinesia Other Serious 1/26/2009 14 Male 8/18/2009 Canada
Primary
Concomitant
Incorrect Dose Administered 4/18/2007 Female 158 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 7/19/2007 Female 138 lb 9/11/2009 Consumer United States
Primary
Concomitant
Rash 9/2/2009 41 Female 177 lb 9/16/2009 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 34 10/1/2009
Primary
Secondary
Withdrawal Syndrome Other Serious 42 10/1/2009
Primary
Secondary
Weight Increased Hospitalization 1/1/2007 49 Female 215 lb 10/2/2009 Consumer United States
Primary
Concomitant
Drug Level Decreased Hospitalization 72 Female 10/2/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious Female 10/7/2009 Consumer Germany
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 34 11/5/2009 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 42 11/5/2009 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 34 11/10/2009 Other Health Professional United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 42 11/10/2009 Other Health Professional United States
Primary
Concomitant
Withdrawal Syndrome Required Intervention 34 11/20/2009 United States
Primary
Concomitant
Irritability Required Intervention 42 11/20/2009 United States
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 12/1/2009 78 Female 1/27/2010 Other Health Professional France
Primary
Concomitant
Urine Leukocyte Esterase Positive Hospitalization 50 Female 1/25/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 Male 1/29/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 48 Female 2/2/2010 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 1/19/2010 48 Female 2/9/2010 Canada
Primary
Concomitant
Social Avoidant Behaviour 1/1/2007 54 Female 2/26/2010 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 12/1/2009 42 Female 2/26/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 Male 2/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hypoaesthesia Oral 10/22/2009 49 Female 3/2/2010 Pharmacist United States
Primary
Concomitant
Hypoaesthesia Oral Female 3/2/2010 Pharmacist United States
Primary
Concomitant
Vulvovaginal Candidiasis Hospitalization 2/1/2010 46 Female 280 lb 3/24/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 41 Male 5/19/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 2/1/2010 Female 5/28/2010 Germany
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/29/2010 80 Female 194 lb 6/4/2010 Pharmacist United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 4/14/2010 58 Female 6/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 4/14/2010 58 Female 6/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting 6/22/2010 66 Female 130 lb 7/6/2010 Consumer United States
Primary
Concomitant
Platelet Count Increased Other Serious 4/14/2010 58 Female 7/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious Female 200 lb 5/17/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 41 Male 8/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 50 Female 8/20/2010 Consumer United States
Primary
Concomitant
Treatment Noncompliance Other Serious Female 8/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Paraesthesia Female 169 lb 8/29/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 41 Male 9/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Pressure Increased 1/1/2009 67 Female 9/20/2010 Consumer United States
Primary
Concomitant
Dyskinesia 1/1/2010 42 Female 150 lb 9/20/2010 Physician United States
Primary
Concomitant
Post-traumatic Stress Disorder Other Serious 8/1/2010 63 Male 190 lb 9/23/2010 Consumer United States
Primary
Concomitant
Road Traffic Accident Life Threatening 3/30/2010 55 Male 250 lb 9/27/2010 Physician United States
Primary
Concomitant
Road Traffic Accident Life Threatening 3/30/2010 55 Male 250 lb 10/5/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2010 53 Female 10/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity 9/10/2010 57 Female 220 lb 11/9/2010 Consumer United States
Primary
Concomitant

Drug Data