Lamotrigine combined with Lansoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Menorrhagia Hospitalization 10/2/2005 47 Female 2/15/2006 United States
Primary
Concomitant
Macrocytosis Other Serious 5/1/2006 Female 251 lb 7/28/2006 Consumer United Kingdom
Primary
Concomitant
Granulocytopenia Required Intervention 3/9/2006 22 Male 5/9/2006 Consumer United States
Primary
Concomitant
Haemorrhage Hospitalization 3/27/2006 Female 130 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 11/8/2006 Male 152 lb 4/20/2007 Pharmacist United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 1/27/2007 67 Male 229 lb 4/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 5/6/2007 35 Female 223 lb 6/19/2007 Consumer United Kingdom
Primary
Concomitant
Sepsis Other Serious 3/27/2006 Female 130 lb 7/20/2007 Consumer United Kingdom
Primary
Concomitant
Sepsis Other Serious 3/27/2006 Female 130 lb 7/30/2007 Consumer United Kingdom
Primary
Concomitant
Status Epilepticus Life Threatening 6/10/2007 19 Male 8/30/2007 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 10/24/2007 53 Female 11/19/2007 Consumer United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 12/9/2007 38 Male 1/3/2008 United Kingdom
Primary
Concomitant
Dystonia Other Serious 61 Female 1/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 12/9/2007 38 Male 2/7/2008 United Kingdom
Primary
Concomitant
Pulse Absent Hospitalization 2/1/2007 87 Male 2/25/2008 France
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 42 Male 3/19/2008 United Kingdom
Primary
Concomitant
Sinus Bradycardia Other Serious 42 Male 3/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Personality Change Hospitalization 2/22/2003 54 Male 8/8/2008 Consumer Denmark
Primary
Secondary
Concomitant
Personality Change Hospitalization 2/22/2003 54 Male 8/13/2008 Consumer Denmark
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 8/12/2008 Male 210 lb 8/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Dystonia Other Serious 12/1/2007 61 Female 8/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus 5/1/2008 Female 222 lb 8/29/2008 Consumer United States
Primary
Concomitant
Headache Female 8/29/2008 United States
Primary
Concomitant
Troponin Increased Hospitalization 8/12/2008 Male 210 lb 8/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Disability 7/31/2008 47 Female 9/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Personality Change Hospitalization 2/22/2003 54 Male 9/4/2008 Consumer Denmark
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 8/12/2008 Male 210 lb 9/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 8/12/2008 Male 210 lb 9/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 10/2/2004 50 Male 9/10/2008 Denmark
Primary
Concomitant
Rash Other Serious 7/31/2008 Female 9/17/2008 Physician United Kingdom
Primary
Concomitant
Hypogammaglobulinaemia Disability 3/5/2009 53 Female 4/10/2009 Consumer United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Disability 3/5/2009 53 Female 4/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypogammaglobulinaemia Disability 3/5/2009 53 Female 4/17/2009 United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/25/2009 75 Female 168 lb 4/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypogammaglobulinaemia Hospitalization 3/5/2009 53 Female 4/24/2009 United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/25/2009 75 Female 168 lb 4/29/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Liver Function Test Abnormal Other Serious 3/25/2009 75 Female 168 lb 4/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/25/2009 75 Female 168 lb 5/6/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Lower Respiratory Tract Infection Other Serious 3/25/2009 75 Female 168 lb 5/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/25/2009 75 Female 168 lb 5/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/25/2009 75 Female 168 lb 5/15/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Liver Function Test Abnormal Other Serious 3/25/2009 75 Female 168 lb 5/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/25/2009 75 Female 168 lb 5/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ocular Icterus Hospitalization 3/25/2009 75 Female 5/27/2009 United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 3/3/2009 42 Female 6/2/2009 United Kingdom
Primary
Concomitant
General Physical Health Deterioration Hospitalization 2/1/2009 Female 9/4/2009 Other Health Professional France
Primary
Concomitant
Hypogammaglobulinaemia Disability 5/3/2009 53 Female 9/15/2009 United Kingdom
Primary
Concomitant
Road Traffic Accident Hospitalization 2/23/2001 59 Male 190 lb 9/23/2009 Other Health Professional United States
Primary
Concomitant
Hemiparesis Hospitalization 12/8/2009 60 Female 12/22/2009 Physician United Kingdom
Primary
Concomitant
Partial Seizures Hospitalization 12/8/2009 60 Female 12/24/2009 Physician United Kingdom
Primary
Concomitant
Partial Seizures Hospitalization 12/8/2009 60 Female 1/19/2010 Physician United Kingdom
Primary
Concomitant
Pancytopenia Other Serious 12/30/2005 41 Male 154 lb 2/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/30/2005 41 Male 154 lb 2/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tinnitus Hospitalization 8/31/2009 34 Female 2/19/2010 Physician Austria
Primary
Concomitant
Partial Seizures Hospitalization 12/8/2009 60 Female 2/26/2010 Physician United Kingdom
Primary
Concomitant
Pyrexia Other Serious 7/31/2008 47 Female 3/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tinnitus Hospitalization 8/31/2009 34 Female 3/29/2010 Physician Austria
Primary
Concomitant
Oesophageal Carcinoma Death Male 4/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization Male 5/6/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/29/2010 80 Female 194 lb 6/4/2010 Pharmacist United Kingdom
Primary
Concomitant
Myoclonus Hospitalization 6/18/2010 97 Male 7/15/2010 Physician United Kingdom
Primary
Concomitant
Myoclonus Hospitalization 6/18/2010 97 Male 7/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Wound Secretion Hospitalization 8/12/2008 Male 210 lb 7/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 6/18/2010 97 Male 7/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Encephalopathy Hospitalization 6/18/2010 97 Male 7/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Myoclonus Hospitalization 6/18/2010 97 Male 7/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Myoclonus Hospitalization 6/18/2010 97 Male 7/31/2010 United Kingdom
Primary
Concomitant
Urine Flow Decreased Other Serious 7/1/2008 21 Male 8/12/2010 Physician United Kingdom
Primary
Concomitant
Myoclonus Hospitalization 6/18/2010 97 Male 8/11/2010 United Kingdom
Primary
Concomitant
Rash Papular Other Serious 8/2/2010 51 Female 8/25/2010 Pharmacist United Kingdom
Primary
Concomitant
Ventricular Septal Defect Other Serious 0 Male 6 lb 9/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Premature Labour Hospitalization 1/22/2010 Female 9/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Premature Labour Other Serious 1/22/2010 36 Female 119 lb 9/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Septal Defect Hospitalization 0 Male 9/16/2010 Physician United Kingdom
Primary
Secondary
Ventricular Septal Defect Hospitalization Male 6 lb 9/14/2010 Physician Denmark
Primary
Secondary
Sexually Transmitted Disease Other Serious 36 Female 119 lb 9/21/2010 Physician United Kingdom
Primary
Concomitant
Ventricular Septal Defect Other Serious 9/21/2010 Physician United Kingdom
Primary
Concomitant
Premature Labour Other Serious 36 Female 9/17/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Ventricular Septal Defect Other Serious 0 Male 6 lb 9/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Premature Labour Hospitalization 1/22/2010 Female 9/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Septal Defect Other Serious 10/4/2010 United Kingdom
Primary
Concomitant
Ventricular Septal Defect Other Serious 36 10/7/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Septal Defect Other Serious 36 10/7/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Septal Defect Other Serious 10/7/2010 United Kingdom
Primary
Concomitant
Sexually Transmitted Disease Other Serious 6/1/2010 36 Female 10/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Sexually Transmitted Disease Other Serious 6/1/2010 36 Female 10/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Septal Defect Other Serious 10/5/2010 Physician
Primary
Concomitant
Sexually Transmitted Disease Other Serious 36 Female 10/11/2010 United Kingdom
Primary
Concomitant
Sexually Transmitted Disease Other Serious 36 Female 119 lb 10/12/2010 Physician
Primary
Concomitant
Sexually Transmitted Disease Other Serious 6/1/2010 36 Female 119 lb 10/15/2010 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/15/2010 74 Male 11/16/2010 Pharmacist Ireland
Primary
Concomitant
Parkinsonism Hospitalization 5/1/2010 69 Female 163 lb 11/29/2010 Physician United Kingdom
Primary
Concomitant
Premature Labour Hospitalization 1/22/2010 36 Female 119 lb 12/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Septal Defect Other Serious 36 Male 16 lb 12/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Parkinsonism Hospitalization 5/1/2010 69 Female 163 lb 12/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Parkinsonism Hospitalization 5/1/2010 69 Female 163 lb 12/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Parkinsonism Hospitalization 5/1/2010 69 Female 163 lb 12/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Septal Defect Hospitalization 5/3/2010 0 Male 16 lb 11/24/2010 Physician Denmark
Primary
Secondary
Parkinsonism Hospitalization 5/1/2010 69 Female 163 lb 12/3/2010
Primary
Concomitant
Parkinsonism Hospitalization 5/1/2010 69 Female 12/2/2010 United Kingdom
Primary
Concomitant
Ocular Icterus Other Serious 3/25/2009 75 Female 12/29/2010 Other Health Professional
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/15/2010 74 Male 1/20/2011 Pharmacist Ireland
Primary
Concomitant
Drug Exposure During Pregnancy Hospitalization 2/24/2011 Physician United Kingdom
Primary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 36 3/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Osteoporosis 1/1/2011 58 Female 1/28/2012 Consumer United States
Primary
Concomitant
Tenderness Other Serious 2/11/2012 55 Male 2/28/2012 Physician Ireland
Primary
Concomitant
Dizziness Other Serious 2/1/2012 60 Male 3/15/2012 Physician Israel
Primary
Concomitant
Vomiting Other Serious 60 Male 3/19/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Oropharyngeal Pain Other Serious 3/1/2012 45 Male 3/23/2012 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 60 Male 4/4/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 1/1/2012 58 Male 6/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 4/13/2012 58 Male 6/6/2012 Other Health Professional
Primary
Secondary
Concomitant
Myocardial Infarction Death Male 7/2/2012 Pharmacist United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Disability 1/2012 51 Female 9/5/2012 Physician Gb
Primary
Concomitant
Stevens-johnson Syndrome Disability 1/2012 51 Female 9/3/2012 Other Health Professional Gb
Primary
Concomitant
Stevens-johnson Syndrome Disability 1/2012 51 Female 9/7/2012 Physician Gb
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/19/2011 47 Male 3/20/2013 Other Health Professional Gb
Primary
Concomitant
Overweight Other Serious 2003 Male 10/31/2012 Consumer Gb
Primary
Concomitant
Prescribed Overdose Other Serious Female 1/29/2013 Physician Us
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 2009 Male 1/28/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 2011 64 Female 1/8/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 64 Female 1/8/2013 Physician Us
Primary
Secondary
Completed Suicide Death 2011 64 Female 2/7/2013 Physician Us
Primary
Secondary
Completed Suicide Other Serious 64 Female 1/19/2013 Physician Us
Primary
Secondary
Completed Suicide Death 2011 64 Female 2/15/2013 Other Health Professional Us
Primary
Secondary
Completed Suicide Death 64 Female 1/18/2013 Physician Country Not Specified
Primary
Secondary
Completed Suicide Death 2011 64 Female 1/18/2013 Physician Us
Primary
Secondary
Completed Suicide Death 64 Female 1/25/2013 Other Health Professional Us
Primary
Secondary
White Blood Cell Count Increased Hospitalization 2009 30 Male 2/8/2013 Physician Gb
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2009 30 Male 2/12/2013 Physician Gb
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 2009 30 Male 2/12/2013 Physician Gb
Primary
Secondary
Concomitant
Rash 2/3/2013 Female 2/6/2013 Pharmacist Us
Primary
Concomitant
Completed Suicide Death 64 Female 2/15/2013 Physician Us
Primary
Secondary
Completed Suicide Death 2011 64 Female 1/14/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 2011 64 Female 1/29/2013 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Death 2011 64 Female 1/22/2013 Other Health Professional Us
Primary
Secondary
Completed Suicide Death 64 Female 2/18/2013 Physician Us
Primary
Secondary
Completed Suicide Death 64 Female 2/8/2013 Other Health Professional Us
Primary
Secondary
Completed Suicide Death 64 Female 2/8/2013 Other Health Professional Us
Primary
Secondary
Urinary Tract Infection Hospitalization 8/2012 28 Male 187 lb 8/17/2013 Physician Gb
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 64 Female 2/27/2013 Physician Country Not Specified
Primary
Secondary
Death Death 64 Female 1/16/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 64 Female 1/25/2013 Country Not Specified
Primary
Secondary
Completed Suicide Death 64 Female 3/5/2013 Physician Us
Primary
Secondary
Concomitant
Poisoning Death 2011 64 Female 2/5/2013 Physician Us
Primary
Secondary
Vomiting Disability 3/5/2013 35 Female 3/22/2013 Other Health Professional Gb
Primary
Concomitant
Urticaria Hospitalization 2/22/2013 57 Female 117 lb 3/19/2013 Physician Gb
Primary
Concomitant
Hyponatraemia Hospitalization 66 Female 9/4/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 66 Female 9/26/2013 Physician Gb
Primary
Secondary
Concomitant

Drug Data