Lamivudine combined with Tenofovir

Reports:

---

Reaction	Outcome	Event Date	Age	Sex	Weight	Reported	Reporter	Country	Treatment
									Role	Name
Nephropathy Toxic	Other Serious		29	Male		1/3/2006	Consumer	Italy	Primary Secondary Concomitant
Renal Tubular Necrosis	Hospitalization		61	Male		1/5/2006	Other Health Professional	United States	Primary Secondary Concomitant
Cephalhaematoma	Congenital Anomaly	10/19/2005		Female	5 lb	1/6/2006		United States	Primary Secondary
Septic Shock	Hospitalization	10/1/2005	48	Male	165 lb	1/6/2006	Other Health Professional	Portugal	Primary Concomitant
Thinking Abnormal	Other Serious	10/1/2005	48	Male	163 lb	1/9/2006	Physician	Portugal	Primary Concomitant
Renal Tubular Necrosis	Other Serious		51	Male		1/11/2006	Other Health Professional	Germany	Primary Secondary
Weight Decreased	Hospitalization	10/19/2005		Male	130 lb	1/12/2006		Switzerland	Primary Concomitant
Vomiting	Life Threatening	12/23/2003		Male		1/12/2006		United Kingdom	Primary Secondary Concomitant
Nephropathy Toxic	Other Serious		29	Male		1/13/2006		Italy	Primary Concomitant Interacting
Liver Disorder	Death	9/10/2005		Female		1/17/2006		Spain	Primary Concomitant
Synovitis	Disability	6/1/2003	39	Male		1/18/2006	Consumer	United States	Primary Secondary
Subdural Haematoma	Other Serious	12/23/2003		Male		1/19/2006		United States	Primary Secondary Concomitant
White Blood Cell Count Decreased	Hospitalization	4/15/2004		Male		1/19/2006		Japan	Primary Secondary Concomitant
Vomiting	Life Threatening	12/23/2003		Male		1/19/2006		United Kingdom	Primary Secondary Concomitant
Drug Withdrawal Syndrome	Hospitalization		51	Male		1/19/2006		Australia	Primary Secondary Concomitant Interacting
Synovitis	Disability	6/1/2003	39	Male		1/20/2006	Consumer	United States	Primary Secondary
Thrombocytopenia	Life Threatening	10/5/2004		Male		1/20/2006		Japan	Primary Secondary Concomitant
Herpes Zoster	Hospitalization	4/21/2004		Male		1/20/2006		Japan	Primary Concomitant
Oral Neoplasm	Hospitalization	5/4/2005	61	Male		1/20/2006		France	Primary Secondary
Staphylococcal Infection	Other Serious	7/9/2004		Male		1/23/2006		Japan	Primary Secondary Concomitant
Respiratory Tract Infection	Hospitalization		51	Male		1/27/2006		Australia	Primary Secondary Concomitant Interacting
Liver Disorder	Hospitalization	4/13/2004		Male		1/27/2006		Japan	Primary Secondary Concomitant
Drug Exposure During Pregnancy	Other Serious			Female		1/27/2006		Spain	Primary Secondary
Vomiting	Hospitalization	2/8/2001		Male		1/27/2006		Japan	Primary Secondary Concomitant
Thinking Abnormal	Other Serious	10/1/2005	48	Male	163 lb	1/31/2006	Physician	Portugal	Primary Concomitant
Isosporiasis	Life Threatening	10/11/2004		Male	115 lb	2/3/2006		Brazil	Primary Secondary Concomitant
Cephalhaematoma	Congenital Anomaly	10/19/2005		Female	5 lb	2/2/2006		United States	Primary Secondary
Isosporiasis	Life Threatening	10/11/2004		Male	115 lb	2/7/2006		Brazil	Primary Secondary Concomitant
Suicide Attempt	Life Threatening	1/4/2005	49	Male	176 lb	2/8/2006	Physician	Australia	Primary Secondary Concomitant
Pulmonary Hypertension	Hospitalization	2/21/2005		Female		2/9/2006		France	Primary Concomitant
Subdural Haematoma	Other Serious	12/23/2003		Male		2/9/2006		United States	Primary Secondary Concomitant
Cholecystitis	Hospitalization	1/30/2006	66	Male	192 lb	2/10/2006	Other Health Professional	Belgium	Primary Concomitant
Bone Tuberculosis	Hospitalization	1/31/2006		Male		2/10/2006		Belgium	Primary Concomitant
Renal Impairment	Hospitalization	7/1/2004		Male		2/10/2006		Japan	Primary Secondary Concomitant
Isosporiasis	Life Threatening	10/11/2004		Male		2/10/2006		Brazil	Primary Concomitant
Vertigo	Disability	4/30/2004	40	Female	119 lb	2/14/2006	Physician	Belgium	Primary Concomitant
Renal Failure	Hospitalization	11/18/2003		Female		2/15/2006	Other Health Professional	United States	Primary Secondary Concomitant
Cephalhaematoma	Other Serious	10/19/2005		Female	5 lb	2/16/2006	Consumer	United States	Primary Secondary
Vertigo	Disability	4/30/2004	40	Female	119 lb	2/20/2006	Physician	Belgium	Primary Concomitant
Pain In Extremity	Other Serious	1/18/2006	34	Male		2/23/2006	Other Health Professional	United Kingdom	Primary Concomitant
Weight Decreased	Other Serious	9/1/2004	44	Male		2/24/2006		United States	Primary Secondary
Rhabdomyolysis	Other Serious	9/1/2003		Male		2/24/2006	Physician	Japan	Primary Secondary Concomitant
Splenic Infarction	Hospitalization		41	Male		2/27/2006		United States	Primary Secondary
Vomiting	Other Serious	9/2/2004		Male		3/3/2006	Other Health Professional	Mexico	Primary Concomitant
Therapeutic Agent Toxicity	Other Serious	2/1/1999	41	Male		3/6/2006	Physician	Germany	Primary Secondary Concomitant
Ventricular Dysfunction	Other Serious	1/1/2005	38	Female	110 lb	3/6/2006	Other Health Professional	France	Primary Secondary Concomitant
Hypomania	Hospitalization	1/11/2006	45	Male		3/7/2006	Pharmacist	United Kingdom	Primary Concomitant
Orchitis	Hospitalization	9/15/2005	38	Male	121 lb	3/9/2006	Physician	Belgium	Primary Concomitant
Liver Disorder	Hospitalization	10/19/2005		Male	130 lb	3/16/2006		Switzerland	Primary Concomitant
Neutropenia	Hospitalization	1/1/2004	48	Male		3/16/2006	Other Health Professional	United Kingdom	Primary Concomitant
Tuberculosis	Hospitalization	4/1/2005		Male		3/17/2006	Physician	Belgium	Primary Concomitant
Weight Decreased	Hospitalization	7/1/2005	51	Female	108 lb	3/20/2006	Other Health Professional	France	Primary Secondary
Viral Mutation Identified	Other Serious					3/21/2006			Primary Secondary
Vomiting	Other Serious		36	Male		3/22/2006	Consumer	United Kingdom	Primary Secondary
Weight Decreased	Other Serious		55	Male		3/22/2006	Consumer	France	Primary Secondary Concomitant
Viral Load Increased	Hospitalization	1/30/2002	44	Male	110 lb	3/22/2006	Physician	Germany	Primary Secondary Concomitant
Toxoplasmosis	Disability		37	Male	143 lb	3/22/2006	Physician	Germany	Primary Secondary Concomitant
Renal Tubular Disorder	Hospitalization	1/30/2006	37	Male		3/23/2006	Other Health Professional	France	Primary Secondary Concomitant
Wound Secretion	Hospitalization	1/1/2004	48	Male	154 lb	3/27/2006	Physician	Germany	Primary Secondary Concomitant
Pyrexia	Other Serious	4/1/2002		Male	139 lb	3/27/2006	Physician	Germany	Primary Secondary Concomitant
Weight Decreased	Other Serious	1/1/1998	42	Male	143 lb	3/27/2006	Physician	Germany	Primary Secondary Concomitant
Weight Decreased	Other Serious		55	Male		3/27/2006	Consumer	France	Primary Secondary Concomitant
Transaminases Increased	Other Serious	1/30/2003	40	Male		3/27/2006	Physician	Germany	Primary Secondary Concomitant
Vomiting	Other Serious	1/1/1996	40	Male	161 lb	3/27/2006	Physician	Germany	Primary Secondary Concomitant
Weight Gain Poor	Other Serious	1/1/2001		Male	181 lb	3/27/2006	Physician	Germany	Primary Secondary Concomitant
Weight Decreased	Other Serious	1/1/2002	38	Male	141 lb	3/28/2006	Physician	Germany	Primary Secondary Concomitant
Transaminases Increased	Other Serious	8/14/2000	52	Male	154 lb	3/28/2006	Physician	Germany	Primary Secondary
Vomiting	Hospitalization	3/31/2005		Male	97 lb	3/28/2006		France	Primary Concomitant
Toxoplasmosis	Disability		37	Male		3/29/2006	Physician	Germany	Primary Secondary Concomitant
Pyrexia	Other Serious	4/1/2002		Male		3/29/2006	Physician	Germany	Primary Secondary Concomitant
Vomiting	Other Serious	1/1/1996	40	Male		3/29/2006	Physician	Germany	Primary Secondary Concomitant
Infection	Death	3/19/2005		Male		3/31/2006		Germany	Primary Concomitant
Renal Failure	Hospitalization	3/20/2006		Male		4/3/2006	Physician	Japan	Primary Secondary Concomitant
Renal Impairment	Hospitalization	7/1/2004		Male		4/6/2006	Physician	Japan	Primary Secondary Concomitant
Lipoma	Other Serious	5/23/2005	33	Male		4/6/2006	Physician	Spain	Primary Concomitant
Somnolence	Hospitalization	9/1/2005	29	Female		4/7/2006	Other Health Professional	France	Primary Secondary Concomitant
Renal Impairment	Other Serious		29	Male	154 lb	3/30/2006	Physician	Italy	Primary Secondary
Vomiting	Hospitalization	3/31/2005		Male	97 lb	4/13/2006		France	Primary Concomitant
Weight Decreased	Hospitalization	10/19/2005		Male	130 lb	4/13/2006		Switzerland	Primary Concomitant
Thrombocytopenia	Life Threatening	10/5/2004		Male		4/13/2006	Physician	Japan	Primary Secondary Concomitant
Vomiting	Hospitalization		33	Female		4/14/2006			Primary Secondary Concomitant
Pyelonephritis Acute	Hospitalization	3/1/2006		Female		4/14/2006	Other Health Professional	Austria	Primary Concomitant
Syncope	Other Serious	1/6/2004		Male		4/17/2006	Other Health Professional	Germany	Primary Secondary
Pyrexia	Other Serious	1/1/1998		Male	154 lb	4/17/2006	Physician	Germany	Primary Secondary Concomitant
Vertigo	Other Serious	7/1/2003		Male	163 lb	4/17/2006	Physician	Germany	Primary Secondary Concomitant
Nephritis	Other Serious	9/1/1997	19	Male	68 lb	4/17/2006	Physician	Germany	Primary Secondary Concomitant
Rales	Hospitalization	1/1/2003		Male	196 lb	4/17/2006	Other Health Professional	Germany	Primary Secondary Concomitant
Renal Failure Acute	Death	7/5/2005		Male	167 lb	4/18/2006		United States	Primary Concomitant
Unevaluable Event	Other Serious	8/1/2005		Male	119 lb	4/20/2006	Physician	France	Primary Concomitant
Tumour Haemorrhage	Hospitalization	1/27/2006	43	Male	141 lb	5/4/2006	Physician	Belgium	Primary Concomitant
Vomiting	Other Serious	9/2/2004		Male		5/4/2006	Other Health Professional	Mexico	Primary Concomitant
Weight Decreased	Other Serious	4/1/1998		Male	139 lb	5/8/2006	Other Health Professional	Germany	Primary Secondary Concomitant
Tuberculosis	Other Serious	1/1/2001		Male	176 lb	5/8/2006	Physician	Germany	Primary Secondary Concomitant
Transaminases Increased	Other Serious	1/1/1996	35	Female	174 lb	5/8/2006	Physician	Germany	Primary Secondary Concomitant
Viral Load Increased	Other Serious	4/1/1999		Male	110 lb	5/8/2006	Physician	Germany	Primary Secondary Concomitant
Weight Decreased	Other Serious	1/1/1999	50	Male	128 lb	5/8/2006	Physician	Germany	Primary Secondary Concomitant
Weight Increased	Other Serious	1/1/1999		Male	134 lb	5/8/2006	Physician	Germany	Primary Secondary Concomitant
Death	Death	7/5/2005		Male	167 lb	5/10/2006		United States	Primary Concomitant
Death	Death	6/30/2005		Male	215 lb	5/10/2006		United States	Primary Concomitant
Melanocytic Naevus	Hospitalization	10/19/2005		Male	130 lb	5/11/2006		Switzerland	Primary Concomitant
Dyspnoea	Life Threatening	2/1/2006		Female	168 lb	5/11/2006	Physician	United States	Primary Secondary Concomitant
Angina Unstable	Life Threatening	2/1/2006	53	Female	168 lb	5/17/2006	Other Health Professional	Canada	Primary Secondary Concomitant
Viral Mutation Identified	Other Serious					5/17/2006			Primary Secondary
Infection	Death	3/19/2005		Male		5/18/2006		Germany	Primary Concomitant
Weight Decreased	Other Serious	4/1/1998		Male	139 lb	5/18/2006	Other Health Professional	Germany	Primary Secondary Concomitant
Death	Death	6/30/2005		Male		5/18/2006		United States	Primary Concomitant
Tuberculosis	Other Serious	1/1/2005	43	Female		5/22/2006	Physician	United Kingdom	Primary Concomitant
Transaminases Increased	Other Serious	8/14/2000	52	Male	154 lb	5/23/2006	Physician	Germany	Primary Secondary
Staphylococcal Infection	Other Serious	7/9/2004		Male		5/26/2006	Physician	Japan	Primary Secondary Concomitant
Mitochondrial Cytopathy	Life Threatening	1/1/2006	47	Male	160 lb	6/1/2006	Pharmacist	Canada	Primary Concomitant
Liver Disorder	Hospitalization	4/13/2004		Male		6/1/2006		Japan	Primary Secondary Concomitant
Somnolence	Hospitalization	9/1/2005	29	Female		6/2/2006	Other Health Professional	United Kingdom	Primary Secondary Concomitant
Thrombocytopenia	Life Threatening	10/5/2004		Male		6/2/2006	Physician	Japan	Primary Secondary Concomitant
Rash Pruritic	Other Serious		50	Male		6/2/2006		Canada	Primary Concomitant Interacting
Mitochondrial Cytopathy	Life Threatening	1/1/2006	47	Male	160 lb	6/6/2006	Pharmacist	Canada	Primary Concomitant
Lipohypertrophy	Other Serious	4/24/2006	42		160 lb	6/6/2006	Physician	Canada	Primary Concomitant
Neutrophil Count Decreased	Disability	11/10/1999		Male		6/7/2006	Physician	Japan	Primary Secondary
Meningitis	Hospitalization	1/2/2003		Male		6/9/2006			Primary Concomitant
Nasopharyngeal Cancer	Death	8/1/2005	73	Male		6/13/2006	Physician	Japan	Primary Concomitant
Thrombocytopenia	Life Threatening	10/5/2004		Male		6/14/2006	Physician	Japan	Primary Secondary Concomitant
Drug Interaction	Hospitalization		36	Male	192 lb	6/16/2006	Other Health Professional	France	Primary Concomitant Interacting
Dyspnoea	Life Threatening	2/1/2006		Female	168 lb	6/16/2006	Physician	United States	Primary Secondary Concomitant
Pyrexia	Other Serious	2/20/2003	39	Female		6/16/2006	Consumer	Canada	Primary Secondary Concomitant
Pancreatitis	Other Serious		51	Male		6/19/2006	Other Health Professional	Denmark	Primary Secondary
Pancreatitis	Other Serious		38	Male		6/19/2006	Other Health Professional	Denmark	Primary Secondary
Pancreatitis	Other Serious		37	Male		6/19/2006	Other Health Professional	Denmark	Primary Secondary
Pancreatitis	Other Serious		30	Male		6/19/2006	Other Health Professional	Denmark	Primary Secondary
Pancreatitis	Other Serious		59	Male		6/20/2006	Other Health Professional	Denmark	Primary Secondary
Pancreatitis	Other Serious		51	Male		6/20/2006	Other Health Professional	Denmark	Primary Secondary
Viral Mutation Identified	Death	11/1/2001	39	Male		6/20/2006			Primary Secondary
Death	Death	9/3/2004		Male		6/22/2006		United States	Primary Concomitant
Pyrexia	Other Serious		52	Male		6/23/2006	Consumer	United Kingdom	Primary Secondary Concomitant
Liver Disorder	Hospitalization	4/13/2004		Male		6/30/2006		Japan	Primary Secondary Concomitant
Drug Ineffective	Death	4/27/2004		Male		6/30/2006		United States	Primary Concomitant
Renal Tubular Necrosis	Hospitalization	3/20/2006		Male		7/5/2006	Physician	Japan	Primary Secondary Concomitant
Weight Decreased	Other Serious			Female		7/6/2006			Primary Secondary
Urine Uric Acid Decreased	Hospitalization	1/30/2006	37	Male		7/7/2006	Other Health Professional	France	Primary Secondary Concomitant
Premature Baby	Other Serious					7/7/2006			Primary Secondary
Pancreatitis	Other Serious		51	Male		7/11/2006	Other Health Professional	France	Primary Secondary
Premature Labour	Other Serious	2/1/2006	25	Female	154 lb	7/13/2006	Physician	United Kingdom	Primary Concomitant
Premature Baby	Other Serious			Female		7/14/2006		Germany	Primary Secondary
Weight Decreased	Other Serious		33	Female		7/14/2006		Germany	Primary Secondary Concomitant
White Blood Cell Count Decreased	Hospitalization		50	Male		7/14/2006		Canada	Primary Secondary Concomitant
Nasopharyngeal Cancer	Death	8/1/2005	73	Male		7/21/2006	Physician	Japan	Primary Concomitant
Treatment Noncompliance	Hospitalization		50	Male		7/20/2006	Pharmacist	Canada	Primary Secondary Concomitant
Thrombocytopenia	Other Serious	9/27/2004		Male		7/27/2006	Physician	Japan	Primary Secondary Concomitant
Thrombocytopenia	Other Serious	9/27/2004		Male		8/4/2006	Physician	Japan	Primary Secondary Concomitant
Tuberculosis	Other Serious	1/1/2005	43	Female	99 lb	8/7/2006	Physician	United Kingdom	Primary Secondary Concomitant
Pancreatitis Acute	Hospitalization	8/21/2002		Male	117 lb	8/11/2006	Physician	Japan	Primary Secondary Concomitant
Viral Mutation Identified	Other Serious			Male		8/15/2006			Primary Secondary