Lamictal combined with Valproate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Other Serious 9/19/2005 54 Female 150 lb 1/17/2006 Consumer Portugal
Primary
Concomitant
Death Death 60 Female 2/14/2006 Physician South Africa
Primary
Concomitant
Swelling Face Other Serious Male 2/28/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral Female 2/28/2006 Consumer United States
Primary
Concomitant
Rash Generalised 1/1/2004 Male 2/28/2006 Consumer United States
Primary
Concomitant
Fall Hospitalization 1/1/2005 Male 2/28/2006 Consumer United States
Primary
Concomitant
Pruritus 1/1/2005 Male 2/28/2006 Consumer United States
Primary
Secondary
Concomitant
Muscle Tightness Male 2/28/2006 Consumer United States
Primary
Concomitant
Rash Pruritic 5/17/2005 60 Female 2/28/2006 Consumer United States
Primary
Concomitant
Rash Male 2/28/2006 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/26/2005 30 Female 2/28/2006 Consumer United States
Primary
Concomitant
Rash 1/1/2005 2/28/2006 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 1/1/2005 36 Female 3/21/2006 Physician Denmark
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 3/12/2006 11 Male 3/27/2006 Physician Romania
Primary
Concomitant
Somnolence Other Serious 1/1/1994 32 Female 121 lb 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Hypospadias Other Serious Male 3/31/2006 Consumer Australia
Primary
Secondary
Hirsutism Other Serious 6/4/1998 3/31/2006 Consumer Australia
Primary
Secondary
Refusal Of Treatment By Patient Other Serious 8/25/2005 44 Male 4/11/2006 Physician Germany
Primary
Concomitant
Drug Level Decreased Other Serious 3/1/2006 10 Female 5/3/2006 Consumer United States
Primary
Concomitant
Drug Level Decreased Other Serious 3/1/2006 10 Female 53 lb 5/31/2006 Other Health Professional United States
Primary
Concomitant
Tonic Convulsion Other Serious 15 Male 6/15/2006 United Kingdom
Primary
Secondary
Tremor Hospitalization Male 6 lb 7/6/2006 Other Health Professional Argentina
Primary
Concomitant
Tonic Convulsion 29 Male 212 lb 1/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Uveitis Hospitalization 8/1/2006 63 Female 9/26/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious Female 11/9/2006 Physician United Kingdom
Primary
Concomitant
Hepatotoxicity Hospitalization 11/9/2006 Physician Switzerland
Primary
Concomitant
Weight Decreased Other Serious 35 Female 11/15/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Pregnancy Other Serious 2/13/2006 0 Male 12/23/2006 Physician Norway
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 5/31/2006 28 Male 214 lb 1/23/2007 Physician Germany
Primary
Secondary
Concomitant
Gilbert's Syndrome Other Serious 1/1/2007 14 Male 1/25/2007 Physician Germany
Primary
Concomitant
Psychomotor Hyperactivity Hospitalization 12/29/2006 32 Male 1/29/2007 Consumer Italy
Primary
Concomitant
Parkinson's Disease Other Serious 48 Male 2/5/2007 Belgium
Primary
Secondary
Concomitant
Overdose Hospitalization 2/5/2007 Male 2/21/2007 Physician China
Primary
Concomitant
Tremor 2/28/2007 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 7/1/2006 15 Male 2/28/2007 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 11/1/2006 Female 3/1/2007 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 2 Female 3/2/2007 Czech Republic
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2007 45 Female 4/4/2007 Consumer United Kingdom
Primary
Concomitant
Personality Change Hospitalization 1/1/2007 8 Female 43 lb 5/21/2007 Pharmacist United Kingdom
Primary
Concomitant
Vision Blurred Hospitalization 6/18/2007 23 Female 7/16/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 6/18/2007 23 Female 7/30/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Transplant Failure Required Intervention 2/7/2007 28 Female 8/20/2007 United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 3 Male 8/31/2007 Consumer Brazil
Primary
Concomitant
Status Epilepticus Life Threatening 6/10/2007 19 Male 8/30/2007 Physician United Kingdom
Primary
Concomitant
Convulsion Other Serious 9/20/2007 Consumer United States
Primary
Concomitant
Insomnia Hospitalization 4/1/2006 42 Male 9/21/2007 Physician Czech Republic
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 4/1/2006 42 Male 10/1/2007 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Pregnancy Other Serious Female 11/9/2007 Other Health Professional Sweden
Primary
Concomitant
Tremor Hospitalization 10/9/2007 Female 11/15/2007 United Kingdom
Primary
Secondary
Concomitant
Polydipsia Other Serious 11/25/2007 14 Male 12/5/2007 Physician Australia
Primary
Concomitant
Spina Bifida Congenital Anomaly Female 6 lb 1/9/2008 United Kingdom
Primary
Secondary
Toxic Shock Syndrome Staphylococcal Hospitalization 10/1/2007 11 Female 1/18/2008 Pharmacist United Kingdom
Primary
Concomitant
Urticaria Hospitalization 3/4/2007 31 Female 1/18/2008 Consumer Sweden
Primary
Concomitant
Toxic Shock Syndrome Staphylococcal Other Serious 10/1/2007 11 Female 79 lb 2/15/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Epilepsy Death 8/10/1995 25 Female 3/3/2008 Consumer Norway
Primary
Concomitant
Somnolence Hospitalization 2/11/2008 2 Male 31 lb 3/7/2008 Physician Australia
Primary
Concomitant
Somnolence Hospitalization 2/11/2008 2 Male 31 lb 3/19/2008 Physician Australia
Primary
Concomitant
Thyroiditis Other Serious 2/1/2008 37 Female 207 lb 3/17/2008 Physician Denmark
Primary
Secondary
International Normalised Ratio Increased Other Serious 1/8/2008 40 Male 3/20/2008 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Required Intervention 2/7/2007 28 Female 143 lb 3/27/2008 United Kingdom
Primary
Concomitant
Thyroiditis Death 2/17/2007 36 Female 4/25/2008 Denmark
Primary
Secondary
International Normalised Ratio Increased Other Serious 1/8/2008 40 Male 5/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Epilepsy Death 8/10/1995 25 Female 5/23/2008 Consumer Norway
Primary
Concomitant
Epilepsy Death 8/10/1995 25 Female 5/29/2008 Consumer Norway
Primary
Concomitant
Serum Ferritin Increased Other Serious 26 Female 6/9/2008 Greece
Primary
Secondary
Thyroxine Free Decreased Other Serious 7/4/2007 5 Female 8/15/2008 Consumer Germany
Primary
Concomitant
Epilepsy Other Serious 72 Female 8/21/2008 Physician Germany
Primary
Concomitant
Maternal Drugs Affecting Foetus Required Intervention Male 9/2/2008 United Kingdom
Primary
Secondary
Ecg Signs Of Myocardial Ischaemia Hospitalization 22 Male 10/2/2008 Physician Germany
Primary
Concomitant
Toxic Shock Syndrome Staphylococcal Life Threatening 10/1/2007 11 Female 79 lb 10/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 43 Female 1/14/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious Female 2/13/2009 Physician United States
Primary
Secondary
Stevens-johnson Syndrome Life Threatening 2/1/2009 7 Female 2/27/2009 Consumer France
Primary
Secondary
Stevens-johnson Syndrome Life Threatening 2/1/2009 7 Female 3/10/2009 Consumer France
Primary
Secondary
Stevens-johnson Syndrome Life Threatening 2/1/2009 7 Female 66 lb 3/19/2009 Consumer France
Primary
Secondary
Tremor Death 8/10/1995 25 Female 3/16/2009 Norway
Primary
Concomitant
Somnolence Hospitalization 9/10/2008 Female 238 lb 3/27/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Somnolence Hospitalization 9/10/2008 78 Female 220 lb 3/30/2009 Physician Germany
Primary
Concomitant
Interacting
Grand Mal Convulsion Hospitalization 3/3/2009 42 Female 223 lb 3/24/2009 United Kingdom
Primary
Concomitant
Skin Disorder Hospitalization Female 4/17/2009 Physician Japan
Primary
Concomitant
Contusion Other Serious Male 5/14/2009 Pharmacist Australia
Primary
Concomitant
Viral Infection Hospitalization 5/1/2009 43 Male 5/15/2009 Physician Japan
Primary
Secondary
Concomitant
Toxic Shock Syndrome Staphylococcal Life Threatening 10/1/2007 11 Female 5/22/2009 France
Primary
Concomitant
Interacting
Skin Disorder Hospitalization Male 5/27/2009 Physician Japan
Primary
Concomitant
Skin Disorder Hospitalization Male 5/29/2009 Physician Japan
Primary
Concomitant
Vulvovaginal Dryness Life Threatening 1/1/2008 Female 6/9/2009 Physician France
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 3/3/2009 Female 6/11/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/23/2009 Male 6/26/2009 Physician Japan
Primary
Concomitant
Skin Disorder Hospitalization 3/3/2009 Female 7/1/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/23/2009 Male 7/8/2009 Physician Japan
Primary
Concomitant
Unevaluable Event Hospitalization 12/23/2007 16 Male 7/7/2009 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/23/2009 Male 7/16/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/23/2009 Male 7/20/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 3/3/2009 Female 7/24/2009 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 7/1/2009 31 Male 8/5/2009 Physician China
Primary
Concomitant
Restlessness Other Serious Male 121 lb 8/25/2009 Physician Germany
Primary
Secondary
Stevens-johnson Syndrome Life Threatening 7/1/2009 31 Male 9/8/2009 Physician China
Primary
Concomitant
Convulsion Hospitalization 6/16/2009 Male 12/1/2009 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2009 16 Male 12/30/2009 Physician China
Primary
Concomitant
Thyroiditis Life Threatening 2/1/2007 36 Female 12/22/2009 Other Health Professional Denmark
Primary
Secondary
Thyroiditis Life Threatening 2/1/2007 36 Female 1/5/2010 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Hospitalization Female 1/21/2010 Physician Germany
Primary
Secondary
Myoclonic Epilepsy Other Serious Female 2/1/2010 Pharmacist United Kingdom
Primary
Concomitant
Toxic Encephalopathy Hospitalization 11/1/2009 60 Female 3/10/2010 Physician Switzerland
Primary
Secondary
Tremor Other Serious 49 Male 5/10/2010 Physician Australia
Primary
Secondary
Concomitant
Sudden Death Death 5/24/2010 43 Female 180 lb 6/7/2010 Physician United States
Primary
Concomitant
Oedema Peripheral Life Threatening 1/1/2009 43 Male 6/11/2010 Physician Germany
Primary
Concomitant
Restlessness Other Serious 1/1/2010 Male 11 lb 6/11/2010 Physician Germany
Primary
Secondary
Restlessness Other Serious 1/1/2010 Male 11 lb 6/18/2010 Physician Germany
Primary
Secondary
Restlessness Other Serious 1/1/2010 Male 11 lb 6/23/2010 Physician Germany
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 6/7/2010 54 Female 6/25/2010 Physician Japan
Primary
Concomitant
Product Substitution Issue Other Serious 1/1/2010 22 Male 6/30/2010 Pharmacist France
Primary
Concomitant
Nausea 7/1/2007 51 Female 212 lb 7/14/2010 Consumer United States
Primary
Concomitant
Tooth Disorder Other Serious Female 121 lb 7/19/2010 Physician Norway
Primary
Concomitant
Tremor Other Serious 5/5/2010 33 Male 7/12/2010 France
Primary
Concomitant
Weight Increased Other Serious 1/1/1990 25 Female 121 lb 7/28/2010 Physician Norway
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 59 Male 143 lb 8/12/2010 Physician Switzerland
Primary
Secondary
Weight Increased Other Serious 1/1/1990 25 Female 8/12/2010 Other Health Professional Norway
Primary
Secondary
Concomitant
Neutropenia 7/1/2010 43 Female 8/16/2010 Physician Norway
Primary
Concomitant
Product Quality Issue Other Serious Male 9/17/2010 Consumer Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 73 Female 10/4/2010 Consumer United States
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 1/1/2009 37 Male 11/10/2010 Pharmacist Japan
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 23 Female 11/18/2010 Consumer Israel
Primary
Concomitant
Accidental Exposure Other Serious 11/11/2010 21 Male 11/23/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/3/2011 Pharmacist Japan
Primary
Concomitant
Coma Hospitalization 10 Female 55 lb 1/3/2011 Consumer China
Primary
Concomitant
Oculomucocutaneous Syndrome Hospitalization 1/5/2011 Physician Japan
Primary
Concomitant
Tonic Convulsion Death 1/1/2010 34 Female 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/13/2011 Physician Japan
Primary
Concomitant
Hyponatraemia Hospitalization 11/1/2010 73 Female 1/13/2011 Physician Switzerland
Primary
Secondary
Concomitant
Hallucination Hospitalization 12/1/2010 33 Female 84 lb 1/21/2011 Consumer Japan
Primary
Secondary
Tremor 45 Female 2/28/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Of Skin Hospitalization 2/19/2011 Male 187 lb 3/8/2011 Physician Japan
Primary
Concomitant
Skin Disorder Hospitalization 95 Female 3/10/2011 Physician Japan
Primary
Concomitant
Blood Lactate Dehydrogenase Increased Hospitalization 3/29/2010 50 Female 97 lb 3/17/2011 Consumer Japan
Primary
Concomitant
Hallucination Hospitalization 12/9/2010 33 Female 84 lb 3/29/2011 Physician Japan
Primary
Secondary
Lymphocyte Count Decreased Hospitalization 3/29/2010 50 Female 97 lb 4/4/2011 Physician Japan
Primary
Concomitant
Oculomucocutaneous Syndrome Hospitalization 50 Female 4/13/2011 Physician Japan
Primary
Concomitant
Hallucination Other Serious 9/1/2010 53 Male 4/15/2011 Physician Japan
Primary
Concomitant
Rash Hospitalization 3/22/2011 63 Male 4/20/2011 Pharmacist Japan
Primary
Concomitant
Oedema Peripheral Other Serious 8/12/2010 53 Male 5/3/2011 Physician Japan
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Other Serious 2/28/2011 1 Male 21 lb 5/19/2011 Consumer France
Primary
Concomitant
Thyroiditis Hospitalization 6/1/2010 7 Female 5/26/2011 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 25 Female 5/27/2011 Consumer Norway
Primary
Secondary
Red Blood Cell Count Increased Hospitalization 3/29/2011 30 Female 6/2/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 2/18/2011 33 Female 6/6/2011 Physician Japan
Primary
Concomitant
Overdose Hospitalization 6/8/2011 20 Female 143 lb 6/13/2011 Consumer Germany
Primary
Secondary
Psychotic Disorder Other Serious 1/1/2011 27 Male 6/21/2011 Pharmacist Canada
Primary
Secondary
Concomitant
Hepatic Cirrhosis Other Serious 6/22/2011 Pharmacist Canada
Primary
Concomitant
Skin Disorder Hospitalization 6/8/2011 30 Male 6/29/2011 Physician Japan
Primary
Concomitant

Drug Data